Page last updated: 2024-08-24

dexfenfluramine and Heart Valve Diseases

dexfenfluramine has been researched along with Heart Valve Diseases in 43 studies

Research

Studies (43)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	17 (39.53)	18.2507
2000's	22 (51.16)	29.6817
2010's	2 (4.65)	24.3611
2020's	2 (4.65)	2.80

Authors

Authors	Studies
Donis, N; Dulgheru, R; Fillet, M; Hego, A; Hulin, A; Lancellotti, P; Maréchal, P; Nchimi, A; Nguyen, ML; Oury, C; Tridetti, J	1
Ceulemans, B; Gammaitoni, A; Keane, MG; Lagae, L; Marchau, F; Paelinck, BP; Pringsheim, M; Schoonjans, AS	1
Bruneval, P; Ennezat, PV; Malergue, MC; Ohanessian, A; Zannis, K	1
Bhattacharyya, S; Davar, J; Mikhailidis, DP; Schapira, AH	1
Golbraikh, A; Grulke, CM; Hajjo, R; Huang, XP; Roth, BL; Setola, V; Tropsha, A	1
Derry, S; Loke, YK; Pritchard-Copley, A	1
Rigolin, VH; Seghatol, FF	1
Decker, P; Gelgand, EA; Prasad, A; Roldan, CA; Shively, BK	1
Gross, SB; Lepor, NE	1
Jollis, JG; Miller, WC; Ryan, T; Sachdev, M	1
Gross, SB; Naqvi, TZ	1
Hess, MA	1
Antier, D; Bonnet, P; Eder, V; Hanton, G; Hyvelin, JM; Lemaire, MC; Rochefort, GY	1
Baird, IM	1
Cherin, P; Godeau, P; Tellier, P	1
Aurigemma, G; Douglas, PS; Erban, S; Kriegel, G; Phillips, RS; Riley, M; Wee, CC	1
Parisi, AF	1
Williamson, DF; Yanovski, SZ	1
Annegers, JF; Moyé, LA	1
Myers, MD	1
Shapiro, S	1
Pallasch, TJ	1
Adams, C; Cohen, A	1
Ellis-Pegler, RB; Hay, KD; Lang, SD; Neutze, JM; Swinburn, BA	1
Ewalenko, M; Richard, C; Vandenbossche, JL	1
SoRelle, R	1
Schultz, S	1
Foreyt, JP; Poston, WS	1
Constantine, G; Davis, KD; Gardin, JM; Leung, C; Reid, CL; Schumacher, D	1
Jick, H	1
Gross, SB	1
Alexander, RE	1
Gill, EA; Roldan, CA; Shively, BK	1
Ballmer, PE; Imoberdorf, R	1
Cheng, TO	1
Ryan, DH	1
Weissman, NJ	1
Carpenter, W; Rudin, R	1
Caccitolo, JA; Connolly, HM; Orszulak, TA; Rubenson, DS; Schaff, HV	1
Bergmann, JF	1

Reviews

13 review(s) available for dexfenfluramine and Heart Valve Diseases

Article	Year
Cardiovascular safety of low-dose fenfluramine in Dravet syndrome: a review of its benefit-risk profile in a new patient population. Current medical research and opinion, 2017, Volume: 33, Issue:10 Topics: Adult; Appetite Depressants; Dexfenfluramine; Epilepsies, Myoclonic; Fenfluramine; Heart Valve Diseases; Humans; Hypertension, Pulmonary; Incidence; Obesity; Phentermine	2017
Drug-induced fibrotic valvular heart disease. Lancet (London, England), 2009, Aug-15, Volume: 374, Issue:9689 Topics: Antiparkinson Agents; Appetite Depressants; Cabergoline; Dexfenfluramine; Dopamine Agonists; Drug Monitoring; Ergolines; Ergotamine; Fenfluramine; Fibrosis; Heart Valve Diseases; Heart Valves; Humans; Methysergide; Migraine Disorders; N-Methyl-3,4-methylenedioxyamphetamine; Patient Selection; Pergolide; Receptors, Serotonin; Serotonin Agents; Serotonin Plasma Membrane Transport Proteins; Vasoconstrictor Agents	2009
Appetite suppressants and valvular heart disease - a systematic review. BMC clinical pharmacology, 2002, Aug-23, Volume: 2 Topics: Appetite Depressants; Clinical Trials as Topic; Cohort Studies; Dexfenfluramine; Fenfluramine; Heart Valve Diseases; Humans; Phentermine	2002
Appetite suppressants and valvular heart disease. Current opinion in cardiology, 2002, Volume: 17, Issue:5 Topics: Appetite Depressants; Carcinoid Heart Disease; Dexfenfluramine; Fenfluramine; Heart Valve Diseases; Humans; Hypertension, Pulmonary; Phentermine; Ultrasonography	2002
Anorexigen-related cardiopulmonary toxicity. Reviews in cardiovascular medicine, 2000,Fall, Volume: 1, Issue:2 Topics: Aminorex; Appetite Depressants; Dexfenfluramine; Echocardiography; Fenfluramine; Heart Valve Diseases; Humans; Hypertension, Pulmonary; Phentermine	2000
Effect of fenfluramine-derivative diet pills on cardiac valves: a meta-analysis of observational studies. American heart journal, 2002, Volume: 144, Issue:6 Topics: Aortic Valve Insufficiency; Appetite Depressants; Dexfenfluramine; Fenfluramine; Heart Valve Diseases; Heart Valves; Humans; Mitral Valve Insufficiency; Phentermine; Serotonin Agents	2002
Anorexigen-induced cardiac valvulopathy and female gender. Current women's health reports, 2003, Volume: 3, Issue:2 Topics: Adult; Appetite Depressants; Dexfenfluramine; Echocardiography; Female; Fenfluramine; Heart Valve Diseases; Humans; Middle Aged; Obesity; Phentermine; Serotonin Receptor Agonists	2003
Current status of fenfluramine/dexfenfluramine-induced cardiac valvulopathy. Journal of the California Dental Association, 1999, Volume: 27, Issue:5 Topics: Antibiotic Prophylaxis; Appetite Depressants; Dental Care for Chronically Ill; Dexfenfluramine; Drug Combinations; Endocarditis, Bacterial; Female; Fenfluramine; Heart Valve Diseases; Humans; Male; Phentermine; Practice Guidelines as Topic; Prevalence	1999
Scientific and legal issues in fenfluramine/dexfenfluramine litigation. Texas medicine, 2000, Volume: 96, Issue:2 Topics: Anti-Obesity Agents; Dexfenfluramine; Fenfluramine; Heart Valve Diseases; Humans; Hypertension, Pulmonary; Legislation, Medical; Neurotoxicity Syndromes; Risk Assessment; Science; Selective Serotonin Reuptake Inhibitors; Serotonin Receptor Agonists; Weight Loss	2000
Appetite suppressants and cardiac valvulopathy. Current clinical perspectives. Advance for nurse practitioners, 1999, Volume: 7, Issue:10 Topics: Appetite Depressants; Dexfenfluramine; Fenfluramine; Heart Valve Diseases; Humans; Hypertension, Pulmonary; Nurse Practitioners; Obesity; Phentermine; Practice Guidelines as Topic; Predictive Value of Tests; Prevalence; Risk Factors; Selective Serotonin Reuptake Inhibitors; United States	1999
[Obesity: principles of drug therapy]. Therapeutische Umschau. Revue therapeutique, 2000, Volume: 57, Issue:8 Topics: Aminorex; Anti-Obesity Agents; Appetite Depressants; Chronic Disease; Combined Modality Therapy; Cyclobutanes; Dexfenfluramine; Diet, Reducing; Drug and Narcotic Control; Germany; Heart Valve Diseases; Humans; Hypertension, Pulmonary; Lactones; Obesity; Orlistat; Phentermine	2000
Use of sibutramine and other noradrenergic and serotonergic drugs in the management of obesity. Endocrine, 2000, Volume: 13, Issue:2 Topics: Adrenergic Agents; Appetite Depressants; Cyclobutanes; Dexfenfluramine; Dextroamphetamine; Fenfluramine; Heart Valve Diseases; Humans; Obesity; Phenylpropanolamine; Serotonin Agents; Weight Loss	2000
Appetite suppressants and valvular heart disease. The American journal of the medical sciences, 2001, Volume: 321, Issue:4 Topics: Age Factors; Appetite Depressants; Dexfenfluramine; Drug Therapy, Combination; Fenfluramine; Heart Valve Diseases; Humans; Multicenter Studies as Topic; Obesity; Phentermine; Randomized Controlled Trials as Topic; United States; United States Food and Drug Administration	2001

Other Studies

30 other study(ies) available for dexfenfluramine and Heart Valve Diseases

Article	Year
Dexfenfluramine and Pergolide Cause Heart Valve Disease via Valve Metabolic Reprogramming and Ongoing Matrix Remodeling. International journal of molecular sciences, 2020, Jun-03, Volume: 21, Issue:11 Topics: Administration, Oral; AMP-Activated Protein Kinases; Animals; Cell Proliferation; Cluster Analysis; Dexfenfluramine; Enzyme Activation; Extracellular Matrix; Female; Gene Expression Regulation; Heart Valve Diseases; Homeostasis; MicroRNAs; p38 Mitogen-Activated Protein Kinases; Pergolide; Rabbits; Sequence Analysis, RNA; Serotonin; Transcriptome; Transforming Growth Factor beta; Tricuspid Valve	2020
Dexfenfluramin: a forgotten cause of aortic stenosis. Acta cardiologica, 2020, Volume: 75, Issue:3 Topics: Aortic Valve Stenosis; Appetite Depressants; Chemically-Induced Disorders; Dexfenfluramine; Echocardiography, Doppler; Endocardium; Exercise Test; Female; Fibrosis; Heart Valve Diseases; Heart Valve Prosthesis Implantation; Humans; Middle Aged; Obesity; Tomography, X-Ray Computed	2020
Development, validation, and use of quantitative structure-activity relationship models of 5-hydroxytryptamine (2B) receptor ligands to identify novel receptor binders and putative valvulopathic compounds among common drugs. Journal of medicinal chemistry, 2010, Nov-11, Volume: 53, Issue:21 Topics: Algorithms; Binding, Competitive; Databases, Factual; Dexfenfluramine; Drug-Related Side Effects and Adverse Reactions; Fenfluramine; Heart Valve Diseases; Ligands; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Radioligand Assay; Receptor, Serotonin, 5-HT2B; Serotonin 5-HT2 Receptor Agonists	2010
Morphology of anorexigen-associated valve disease by transthoracic and transesophageal echocardiography. The American journal of cardiology, 2002, Dec-01, Volume: 90, Issue:11 Topics: Adult; Aortic Valve; Appetite Depressants; Body Mass Index; Dexfenfluramine; Drug Combinations; Echocardiography, Transesophageal; Female; Fenfluramine; Heart Valve Diseases; Humans; Middle Aged; Mitral Valve; Obesity; Phentermine	2002
Taking things to heart. Journal of the American Dietetic Association, 2004, Volume: 104, Issue:7 Topics: Appetite Depressants; Dexfenfluramine; Drug Combinations; Fenfluramine; Heart Valve Diseases; Humans; Obesity; Phentermine	2004
Dexfenfluramine does not worsen but moderates progression of chronic hypoxia-induced pulmonary hypertension. European journal of pharmacology, 2006, Nov-21, Volume: 550, Issue:1-3 Topics: Animals; Blood Pressure; Body Weight; Chronic Disease; Dexfenfluramine; Disease Progression; Female; Heart Valve Diseases; Hypertension, Pulmonary; Hypoxia; Lung; Myocardium; Organ Size; Rats; Rats, Wistar; Serotonin Receptor Agonists; Ultrasonography, Doppler; Ventricular Function, Left; Ventricular Function, Right; Weight Gain	2006
Risks of heart-valve abnormalities with appetite suppressants. Lancet (London, England), 1998, Oct-31, Volume: 352, Issue:9138 Topics: Appetite Depressants; Dexfenfluramine; Female; Fenfluramine; Heart Valve Diseases; Humans; Risk Factors	1998
[Pulmonary hypertension and heart valve diseases induced by fenfluramine? Hypothesis or certitude? Myth or reality?]. La Revue de medecine interne, 1998, Volume: 19, Issue:10 Topics: Animals; Aortic Valve Insufficiency; Appetite Depressants; Dexfenfluramine; Female; Fenfluramine; Heart Valve Diseases; Humans; Hypertension, Pulmonary; Male; Middle Aged; Mitral Valve Insufficiency; Phentermine; Risk Factors	1998
Risk for valvular heart disease among users of fenfluramine and dexfenfluramine who underwent echocardiography before use of medication. Annals of internal medicine, 1998, 12-01, Volume: 129, Issue:11 Pt 1 Topics: Adult; Appetite Depressants; Cohort Studies; Dexfenfluramine; Disease Progression; Echocardiography; Female; Fenfluramine; Follow-Up Studies; Heart Valve Diseases; Heart Valves; Humans; Male; Middle Aged; Retrospective Studies; Risk Factors; Single-Blind Method; Statistics, Nonparametric	1998
Diet-drug debacle. Annals of internal medicine, 1998, Dec-01, Volume: 129, Issue:11 Topics: Appetite Depressants; Dexfenfluramine; Fenfluramine; Heart Valve Diseases; Humans; Obesity; United States; United States Food and Drug Administration	1998
Studies confirm link between fen-phen and heart-valve disease. Harvard heart letter : from Harvard Medical School, 1998, Volume: 9, Issue:4 Topics: Appetite Depressants; Cyclobutanes; Dexfenfluramine; Drug Combinations; Fenfluramine; Heart Valve Diseases; Humans; Obesity; Phentermine	1998
Appetite-suppressant drugs and valvular heart disease. The New England journal of medicine, 1999, Feb-11, Volume: 340, Issue:6 Topics: Appetite Depressants; Data Interpretation, Statistical; Dexfenfluramine; Fenfluramine; Heart Valve Diseases; Humans; Prevalence; Risk	1999
Appetite-suppressant drugs and valvular heart disease. The New England journal of medicine, 1999, Feb-11, Volume: 340, Issue:6 Topics: Appetite Depressants; Confidence Intervals; Dexfenfluramine; Dose-Response Relationship, Drug; Heart Valve Diseases; Humans; Prevalence; Research Design; Risk	1999
Appetite-suppressant drugs and valvular heart disease. The New England journal of medicine, 1999, Feb-11, Volume: 340, Issue:6 Topics: Appetite Depressants; Dexfenfluramine; Heart Valve Diseases; Humans; Incidence; Obesity; Research Design	1999
Appetite-suppressant drugs and valvular heart disease. The New England journal of medicine, 1999, Feb-11, Volume: 340, Issue:6 Topics: Appetite Depressants; Bias; Dexfenfluramine; Fenfluramine; Heart Valve Diseases; Humans; Obesity; Odds Ratio; Phentermine; Prevalence	1999
[Appetite suppressants and heart valve disorders]. Archives des maladies du coeur et des vaisseaux, 1999, Volume: 92, Issue:9 Topics: Adult; Aged; Aortic Valve Insufficiency; Appetite Depressants; Dexfenfluramine; Female; Fenfluramine; Heart Valve Diseases; Humans; Hypertension, Pulmonary; Middle Aged; Mitral Valve Insufficiency; Phentermine; Pulmonary Valve Insufficiency; Serotonin Agents; Serotonin Receptor Agonists	1999
Prevention of infective endocarditis associated with dental treatment and other medical interventions. National Heart Foundation. The New Zealand dental journal, 1999, Volume: 95, Issue:421 Topics: Adult; Anti-Obesity Agents; Antibiotic Prophylaxis; Aortic Valve Insufficiency; Cefuroxime; Cephalosporins; Child; Child, Preschool; Dental Care; Dexfenfluramine; Drug Prescriptions; Endocarditis, Bacterial; Fenfluramine; Heart Diseases; Heart Valve Diseases; Humans; Mitral Valve Insufficiency; Prodrugs; Risk Factors; Serotonin Receptor Agonists	1999
[Fenfluramines and cardiac valvular lesions]. Revue medicale de Bruxelles, 1999, Volume: 20, Issue:5 Topics: Adult; Aged; Dexfenfluramine; Echocardiography, Doppler; Electrocardiography, Ambulatory; Female; Fenfluramine; Follow-Up Studies; Heart Valve Diseases; Humans; Mass Screening; Middle Aged; Risk Factors; Selective Serotonin Reuptake Inhibitors; Serotonin Receptor Agonists; Time Factors	1999
Diet drug maker agrees to $3.75 billion settlement. Circulation, 1999, Dec-21, Volume: 100, Issue:25 Topics: Dexfenfluramine; Drug Industry; Fenfluramine; Heart Valve Diseases; Humans; United States	1999
A big fat settlement. But lawyers for diet-drug users suggest that $3.75 billion is not nearly enough. U.S. news & world report, 1999, Oct-18, Volume: 127, Issue:15 Topics: Appetite Depressants; Dexfenfluramine; Drug Industry; Heart Valve Diseases; Humans; Hypertension, Pulmonary; Liability, Legal; Serotonin Receptor Agonists; United States	1999
Valvular abnormalities and cardiovascular status following exposure to dexfenfluramine or phentermine/fenfluramine. JAMA, 2000, Apr-05, Volume: 283, Issue:13 Topics: Aortic Valve Insufficiency; Appetite Depressants; Body Mass Index; Dexfenfluramine; Echocardiography, Doppler; Female; Fenfluramine; Heart Valve Diseases; Heart Valves; Humans; Logistic Models; Male; Matched-Pair Analysis; Middle Aged; Mitral Valve Insufficiency; Obesity; Phentermine; Prevalence; Risk; Serotonin Agents; Statistics, Nonparametric	2000
Heart valve disorders and appetite-suppressant drugs. JAMA, 2000, Apr-05, Volume: 283, Issue:13 Topics: Appetite Depressants; Dexfenfluramine; Fenfluramine; Heart Valve Diseases; Humans; Phentermine; Serotonin Agents	2000
More on heart disease and diet pills. Harvard heart letter : from Harvard Medical School, 2000, Volume: 10, Issue:11 Topics: Appetite Depressants; Dexfenfluramine; Fenfluramine; Heart Valve Diseases; Humans; Serotonin Agents	2000
Cardiac valvulopathy. Journal of the American Dental Association (1939), 2000, Volume: 131, Issue:7 Topics: Antibiotic Prophylaxis; Appetite Depressants; Dental Care; Dexfenfluramine; Fenfluramine; Heart Valve Diseases; Humans; Phentermine; Practice Guidelines as Topic; Risk Factors	2000
Prevalence and diagnostic value of precordial murmurs for valvular regurgitation in obese patients treated with dexfenfluramine. The American journal of cardiology, 2000, Sep-01, Volume: 86, Issue:5 Topics: Case-Control Studies; Dexfenfluramine; Echocardiography, Doppler, Color; Female; Heart Auscultation; Heart Murmurs; Heart Valve Diseases; Humans; Male; Middle Aged; Obesity; Prevalence; Serotonin Receptor Agonists	2000
Fen/Phen and valvular heart disease: the final link has now been established. Circulation, 2000, Dec-12, Volume: 102, Issue:24 Topics: Dexfenfluramine; Heart Valve Diseases; Humans; Prognosis; Serotonin Receptor Agonists	2000
Diet drugs and cardiac valvulopathy: a survey of dental patients. Journal of the California Dental Association, 2000, Volume: 28, Issue:12 Topics: Adult; Antibiotic Prophylaxis; Appetite Depressants; Dental Care; Dexfenfluramine; Endocarditis, Bacterial; Fenfluramine; Follow-Up Studies; Heart Valve Diseases; Humans; Phentermine; Prevalence; Serotonin Agents; Serotonin Receptor Agonists; Surveys and Questionnaires	2000
Valve disease due to appetite suppressants (cont'd). Prescrire international, 1999, Volume: 8, Issue:42 Topics: Aortic Valve; Appetite Depressants; Clinical Trials as Topic; Dexfenfluramine; Fenfluramine; Heart Valve Diseases; Humans; Mitral Valve; Phentermine; Selective Serotonin Reuptake Inhibitors; Treatment Outcome	1999
Operation for anorexigen-associated valvular heart disease. The Journal of thoracic and cardiovascular surgery, 2001, Volume: 122, Issue:4 Topics: Adult; Appetite Depressants; Dexfenfluramine; Female; Fenfluramine; Heart Valve Diseases; Humans; Middle Aged; Phentermine; Serotonin Agents; Serotonin Receptor Agonists; Ultrasonography	2001
[Facts, fakes and "biblio". Do internists still have something to learn about dexfenfluramine?]. Annales de medecine interne, 2001, Volume: 152, Issue:7 Topics: Dexfenfluramine; Heart Valve Diseases; Humans; Hypertension, Pulmonary; Obesity; Serotonin Antagonists	2001