Page last updated: 2024-08-24

dexfenfluramine and Body Weight

dexfenfluramine has been researched along with Body Weight in 16 studies

Research

Studies (16)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (6.25)	18.2507
2000's	13 (81.25)	29.6817
2010's	2 (12.50)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Ball, RG; Bateman, TJ; Chen, RZ; Debenham, JS; Fong, TM; Hale, JJ; Huo, P; Lao, J; Madsen-Duggan, CB; Reddy, VB; Shearman, LP; Shen, CP; Strack, AM; Stribling, DS; Tong, X; Tsou, N; Wang, J; Xiao, JC; Yan, L	1
Bakshi, RK; Chen, AS; Chen, HY; Dellureficio, JP; Dobbelaar, PH; Fong, TM; Franklin, CL; Guo, L; He, S; Hong, Q; Jian, T; Lai, Y; Liu, J; Macneil, T; Miller, RR; Nargund, RP; Peng, Q; Sebhat, IK; Stearns, RA; Strack, AM; Tamvakopoulos, C; Tang, R; Weinberg, DH; Wyvratt, MJ; Ye, Z	1
Brindley, DN; DeAlmeida, J; Mitani, Y; Mutlu, A; Rabinovitch, M; Russell, JC	1
Arlt, VM; De Prez, E; Debelle, F; Deschodt-Lanckman, M; Nortier, J; Phillips, DH; Salmon, I; Vanherweghem, JL; Vienne, A	1
Bush, EN; Esbenshade, TA; Faghih, R; Hancock, AA; Jacobson, PB	1
Alemany, M; Cabot, C; Fernández-López, JA; Ferrer-Lorente, R; Remesar, X	1
Elmas, C; Ercan, ZS; Erdoüan, D; Gönül, B; Ozer, C	1
Brune, ME; Bush, EN; Droz, BA; Fey, T; Jacobson, PB; Knourek-Segel, VE; Lin, E; Shapiro, R	1
Coşkun, S; Elmas, C; Erdoğan, D; Gönül, B; Ozer, C	1
Antier, D; Bonnet, P; Eder, V; Hanton, G; Hyvelin, JM; Lemaire, MC; Rochefort, GY	1
Drouin, P; Hanotin, C; Jones, SP; Leutenegger, E; Thomas, F	1
Kalia, M; Kramer, M; Miller, DB; O'Callaghan, JP	1
Herrmann, S; Riches, FM; Watts, GF	1
Christensen, HD; Gonzalez, CL; Kupiec, TC; Paulsen, AL; Rayburn, WF; Sienko, AE; Stewart, JD	1
Dib, B; Falchi, M; Ferrara, F; Gharib, C	1
Balestri, P; Berardi, R; Di Bartolo, R; Farnetani, MA; Grosso, S; Magi, L; Morgese, G	1

Trials

2 trial(s) available for dexfenfluramine and Body Weight

Article	Year
A comparison of sibutramine and dexfenfluramine in the treatment of obesity. Obesity research, 1998, Volume: 6, Issue:4 Topics: Adult; Appetite Depressants; Body Constitution; Body Mass Index; Body Weight; Cyclobutanes; Dexfenfluramine; Double-Blind Method; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Obesity; Serotonin Receptor Agonists; Treatment Outcome	1998
Effects of diet and serotonergic agonist on hepatic apolipoprotein B-100 secretion and endothelial function in obese men. QJM : monthly journal of the Association of Physicians, 2000, Volume: 93, Issue:3 Topics: Apolipoproteins B; Body Weight; Case-Control Studies; Dexfenfluramine; Diet, Reducing; Double-Blind Method; Endothelium, Vascular; Gas Chromatography-Mass Spectrometry; Humans; Insulin; Magnetic Resonance Imaging; Male; Middle Aged; Obesity; Plethysmography; Serotonin Receptor Agonists; Vasodilation	2000

Article

Year

A comparison of sibutramine and dexfenfluramine in the treatment of obesity.

Obesity research, 1998, Volume: 6, Issue:4

Topics: Adult; Appetite Depressants; Body Constitution; Body Mass Index; Body Weight; Cyclobutanes; Dexfenfluramine; Double-Blind Method; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Obesity; Serotonin Receptor Agonists; Treatment Outcome

1998

Effects of diet and serotonergic agonist on hepatic apolipoprotein B-100 secretion and endothelial function in obese men.

QJM : monthly journal of the Association of Physicians, 2000, Volume: 93, Issue:3

Topics: Apolipoproteins B; Body Weight; Case-Control Studies; Dexfenfluramine; Diet, Reducing; Double-Blind Method; Endothelium, Vascular; Gas Chromatography-Mass Spectrometry; Humans; Insulin; Magnetic Resonance Imaging; Male; Middle Aged; Obesity; Plethysmography; Serotonin Receptor Agonists; Vasodilation

2000

Other Studies

14 other study(ies) available for dexfenfluramine and Body Weight

Article	Year
Discovery of N-[(4R)-6-(4-chlorophenyl)-7-(2,4-dichlorophenyl)-2,2-dimethyl-3,4-dihydro-2H-pyrano[2,3-b]pyridin-4-yl]-5-methyl-1H-pyrazole-3-carboxamide (MK-5596) as a novel cannabinoid-1 receptor (CB1R) inverse agonist for the treatment of obesity. Journal of medicinal chemistry, 2010, May-27, Volume: 53, Issue:10 Topics: Animals; Anti-Obesity Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding, Competitive; Body Weight; Cell Line; Cricetinae; Cricetulus; Crystallography, X-Ray; Dogs; Drug Inverse Agonism; Eating; Ether-A-Go-Go Potassium Channels; Glucuronides; Haplorhini; Hepatocytes; Humans; Mice; Mice, Knockout; Models, Molecular; Molecular Conformation; Pyrans; Pyridines; Rats; Receptor, Cannabinoid, CB1; Stereoisomerism; Structure-Activity Relationship	2010
Spiroindane based amides as potent and selective MC4R agonists for the treatment of obesity. Bioorganic & medicinal chemistry letters, 2010, Aug-01, Volume: 20, Issue:15 Topics: Amides; Animals; Anti-Obesity Agents; Body Weight; Humans; Mice; Mice, Knockout; Obesity; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptor, Melanocortin, Type 4; Spiro Compounds; Structure-Activity Relationship	2010
Dexfenfluramine protects against pulmonary hypertension in rats. Journal of applied physiology (Bethesda, Md. : 1985), 2002, Volume: 93, Issue:5 Topics: Animals; Appetite Depressants; Body Weight; Dexfenfluramine; Eating; Endothelium, Vascular; Female; Hemodynamics; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Monocrotaline; Myocardium; Nitric Oxide Synthase; Obesity; Organ Size; Pancreatic Elastase; Pulmonary Artery; Rats; Rats, Mutant Strains; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Vascular Diseases	2002
Effects of dexfenfluramine on aristolochic acid nephrotoxicity in a rat model for Chinese-herb nephropathy. Archives of toxicology, 2003, Volume: 77, Issue:4 Topics: Animals; Aristolochic Acids; Autoradiography; Body Weight; Creatinine; Dexfenfluramine; Disease Models, Animal; DNA Adducts; Drug Synergism; Drugs, Chinese Herbal; Fibrosis; Injections, Subcutaneous; Kidney; Liver; Longevity; Male; Mutagens; Nephritis, Interstitial; Phosphorus Radioisotopes; Rats; Rats, Wistar; Serotonin Receptor Agonists	2003
Histamine H(3) antagonists in models of obesity. Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2004, Volume: 53 Suppl 1 Topics: Animals; Body Weight; Dexfenfluramine; Diet; Histamine Antagonists; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Obesity; Receptors, Histamine H3	2004
Effects of oleoyl-estrone with dexfenfluramine, sibutramine or phentermine on overweight rats. European journal of pharmacology, 2005, Apr-25, Volume: 513, Issue:3 Topics: Animals; Anti-Obesity Agents; Body Weight; Cyclobutanes; Dexfenfluramine; Drug Interactions; Drug Therapy, Combination; Energy Metabolism; Estrone; Insulin; Lipids; Male; Obesity; Oleic Acids; Phentermine; Rats; Rats, Wistar	2005
Effects of dexfenfluramine on serotonin levels of mice ileum, contractility, glutathione and malondialdehyde level. Molecular and cellular biochemistry, 2005, Volume: 280, Issue:1-2 Topics: Animals; Body Weight; Control Groups; Dexfenfluramine; Feeding Behavior; Glutathione; Ileum; Malondialdehyde; Mice; Muscle Contraction; Oxidation-Reduction; Serotonin	2005
Chronic treatment with either dexfenfluramine or sibutramine in diet-switched diet-induced obese mice. Endocrine, 2006, Volume: 29, Issue:2 Topics: Animals; Anti-Obesity Agents; Body Weight; Cyclobutanes; Dexfenfluramine; Diet, Fat-Restricted; Ghrelin; Growth Hormone; Male; Mice; Obesity; Peptide Hormones; Thinness; Weight Gain	2006
The effects of dexfenfluramine administration on brain serotonin immunoreactivity and lipid peroxidation in mice. Cell biology and toxicology, 2007, Volume: 23, Issue:2 Topics: Animals; Appetite Depressants; Body Weight; Brain; Dexfenfluramine; Eating; Glutathione; Immunohistochemistry; Lipid Peroxidation; Male; Mice; Nitric Oxide; Serotonin; Thiobarbituric Acid Reactive Substances	2007
Dexfenfluramine does not worsen but moderates progression of chronic hypoxia-induced pulmonary hypertension. European journal of pharmacology, 2006, Nov-21, Volume: 550, Issue:1-3 Topics: Animals; Blood Pressure; Body Weight; Chronic Disease; Dexfenfluramine; Disease Progression; Female; Heart Valve Diseases; Hypertension, Pulmonary; Hypoxia; Lung; Myocardium; Organ Size; Rats; Rats, Wistar; Serotonin Receptor Agonists; Ultrasonography, Doppler; Ventricular Function, Left; Ventricular Function, Right; Weight Gain	2006
Comparative study of fluoxetine, sibutramine, sertraline and dexfenfluramine on the morphology of serotonergic nerve terminals using serotonin immunohistochemistry. Brain research, 2000, Mar-06, Volume: 858, Issue:1 Topics: Animals; Appetite Depressants; Body Weight; Cyclobutanes; Dexfenfluramine; Eating; Fluoxetine; Immunohistochemistry; Male; N-Methyl-3,4-methylenedioxyamphetamine; Prefrontal Cortex; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Agents; Serotonin Receptor Agonists; Sertraline	2000
Impact of antenatal exposure of mice to fenfluramine on cardiac development and long-term growth of the offspring. Drug and chemical toxicology, 2000, Volume: 23, Issue:3 Topics: Abnormalities, Drug-Induced; Animals; Animals, Newborn; Aortic Valve; Body Weight; Brain; Dexfenfluramine; Embryonic and Fetal Development; Female; Fenfluramine; Fertility; Heart; Litter Size; Male; Mice; Mice, Inbred Strains; Mitral Valve; Pregnancy; Selective Serotonin Reuptake Inhibitors; Tissue Distribution	2000
Intracerebroventricular capsaicin and food intake in the rat. Drugs under experimental and clinical research, 2001, Volume: 27, Issue:2 Topics: Animals; Body Temperature; Body Weight; Brain; Capsaicin; Dexfenfluramine; Eating; Injections, Intraventricular; Male; Rats; Rats, Sprague-Dawley	2001
Dexfenfluramine effective in drug-resistant temporal lobe epilepsy. Neurology, 2001, Sep-25, Volume: 57, Issue:6 Topics: Adolescent; Anticonvulsants; Body Weight; Dexfenfluramine; Electroencephalography; Epilepsy, Temporal Lobe; Female; Humans; Recurrence; Serotonin Receptor Agonists; Substance Withdrawal Syndrome	2001