Page last updated: 2024-11-08

desoxycorticosterone acetate and Disease Models, Animal

desoxycorticosterone acetate has been researched along with Disease Models, Animal in 89 studies

Desoxycorticosterone Acetate: The 21-acetate derivative of desoxycorticosterone.

Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.

Research Excerpts

ExcerptRelevanceReference
"Our study demonstrated the protective effect of resveratrol and exercise on hypertension-induced cardiac dysfunction by modulating cellular stress responses including oxidative stress, ER stress, mitophagy, NLRP3 inflammasome-mediated inflammation, and mitogenic activation."8.12Resveratrol and regular exercise may attenuate hypertension-induced cardiac dysfunction through modulation of cellular stress responses. ( Bal, NB; Bostanci, A; Demirel-Yilmaz, E; Dönmez, MO; Sadi, G; Uludag, MO, 2022)
"Equol-treated DHRs showed a significant decrease in both the swimming distance and time required to reach the escape platform (78."5.43Effects of equol on deoxycorticosterone acetate salt-induced hypertension and associated vascular dementia in rats. ( Liu, TH; Tsai, TY, 2016)
"Our study demonstrated the protective effect of resveratrol and exercise on hypertension-induced cardiac dysfunction by modulating cellular stress responses including oxidative stress, ER stress, mitophagy, NLRP3 inflammasome-mediated inflammation, and mitogenic activation."4.12Resveratrol and regular exercise may attenuate hypertension-induced cardiac dysfunction through modulation of cellular stress responses. ( Bal, NB; Bostanci, A; Demirel-Yilmaz, E; Dönmez, MO; Sadi, G; Uludag, MO, 2022)
"Aspirin prevented aneurysm rupture in a mouse intracranial aneurysm model, while cilostazol did not."3.88Prevention Effect of Antiplatelets on Aneurysm Rupture in a Mouse Intracranial Aneurysm Model. ( Hiramatsu, H; Hokamura, K; Kamio, Y; Kimura, T; Makino, H; Namba, H; Suzuki, T; Umemura, K; Yamasaki, T, 2018)
"Chlorisondamine (CSD) has been used to assess the neurogenic contribution to blood pressure (BP) and vasomotor sympathetic tone in animal models."1.62Use of chlorisondamine to assess the neurogenic contribution to blood pressure in mice: An evaluation of method. ( Cooper, SG; Feng Earley, Y; Souza, LA; Thakore, P; Worker, CJ, 2021)
" In this study, we evaluated the efficacy of firibastat in combination with enalapril, an angiotensin I-converting enzyme inhibitor, and hydrochlorothiazide (HCTZ), in conscious hypertensive deoxycorticosterone acetate (DOCA)-salt rats, which display high plasma arginine-vasopressin levels, low circulating renin levels and resistance to treatment by systemic RAS blockers."1.62Effects of firibastat in combination with enalapril and hydrochlorothiazide on blood pressure and vasopressin release in hypertensive DOCA-salt rats. ( Balavoine, F; De Mota, N; Hmazzou, R; Llorens-Cortes, C; Marc, Y, 2021)
"Hypertension was induced in swine by subcutaneous implantation of deoxycorticosterone acetate pellets in combination with a high-salt diet."1.62Renal Denervation by Noninvasive Stereotactic Radiotherapy Induces Persistent Reduction of Sympathetic Activity in a Hypertensive Swine Model. ( Cai, J; Cai, X; Chen, T; Chen, X; Chi, R; Fei, Y; Han, Y; Jiang, M; Li, K; Li, YG; Liu, M; Liu, Y; Qian, L; Shen, Y; Wang, D; Wang, W; Wei, Z; Yang, Y; Yu, S, 2021)
"Hypertension is an important risk factor for cardiovascular diseases."1.56Reversal of deleterious effect of hypertension on the liver by inhibition of endoplasmic reticulum stress. ( Bal, NB; Demirel-Yilmaz, E; Han, S; Kiremitci, S; Uludag, MO, 2020)
"Hypertension was induced by deoxycorticosterone acetate (DOCA)-salt administration in uninephrectomized rats for 6 weeks."1.51Activation of Liver X Receptors by GW3965 Attenuated Deoxycorticosterone Acetate-Salt Hypertension-Induced Cardiac Functional and Structural Changes. ( Bal, NB; Demirel-Yilmaz, E; Han, S; Kiremitci, S; Sadi, G; Uludag, O; Usanmaz, SE, 2019)
"Hypertension was induced by deoxycorticosterone-acetate (DOCA) and salt administration in uni-nephrectomized rats for 12 weeks."1.51Hypertension-induced cardiac impairment is reversed by the inhibition of endoplasmic reticulum stress. ( Bal, NB; Demirel-Yilmaz, E; Han, S; Kiremitci, S; Sadi, G; Uludag, O, 2019)
"Aldosterone is a key factor in adverse cardiovascular remodeling by acting on the mineralocorticoid receptor (MR) in different cell types."1.51Endothelial cell mineralocorticoid receptors oppose VEGF-induced gene expression and angiogenesis. ( Bode, C; Deng, L; Esser, JS; Fürst, D; Hein, L; Huck, M; Kowalski, J; Lother, A; Moser, M, 2019)
"Hypertension has complex vascular pathogenesis and therefore the molecular etiology remains poorly elucidated."1.51Inhibition of endoplasmic reticulum stress protected DOCA-salt hypertension-induced vascular dysfunction. ( Bal, NB; Demirel-Yilmaz, E; Han, S; Sadi, G; Tuglu, MM; Uludag, MO; Usanmaz, SE, 2019)
" The aim of this study was to compare the effect of chronic administration of URB597, the FAAH (fatty acid amide hydrolase) inhibitor, to rats with primary (SHRs) and secondary (DOCA-salt hypertensive rats) hypertension on electrical and physicochemical properties of kidney cells membranes."1.51Changes in physicochemical properties of kidney cells membrane as a consequence of hypertension and treatment of hypertensive rats with FAAH inhibitor. ( Dobrzyńska, I; Figaszewski, ZA; Skrzydlewska, E; Szachowicz-Petelska, B; Weresa, J, 2019)
"Metformin-treated mice have unaltered PEVK phosphorylation but increased phosphorylation of PKA sites in the N2B element, a change which has previously been shown to lower titin's stiffness."1.51Metformin improves diastolic function in an HFpEF-like mouse model by increasing titin compliance. ( Gotthardt, M; Granzier, HL; Liss, M; Methawasin, M; Slater, RE; Strom, JG; Sweitzer, N, 2019)
"Protocatechuic acid (PCA) is a natural antioxidant with beneficial cardiovascular properties."1.48Antihypertensive and antioxidant effects of protocatechuic acid in deoxycorticosterone acetate-salt hypertensive rats. ( Emami, R; Haghighatian, Z; Hajhashemi, V; Safaeian, L, 2018)
"Hypertension was induced through unilateral nephrectomy and deoxycorticosterone-acetate (DOCA) injection (20 mg/kg, twice a week) for 6 weeks in male Wistar albino rats (8 weeks old)."1.48The effects of LXR agonist GW3965 on vascular reactivity and inflammation in hypertensive rat aorta. ( Bal, NB; Demirel-Yilmaz, E; Han, S; Sadi, G; Uludag, MO; Usanmaz, SE, 2018)
"Hypertension was promoted by subcutaneous injection of deoxycorticosterone acetate (DOCA, 25 mg/kg body weight/day, twice a week) and substitution of drinking water with 1."1.46Prevention of hypertension-induced vascular dementia by Lactobacillus paracasei subsp. paracasei NTU 101-fermented products. ( Cheng, MC; Pan, TM, 2017)
"Equol-treated DHRs showed a significant decrease in both the swimming distance and time required to reach the escape platform (78."1.43Effects of equol on deoxycorticosterone acetate salt-induced hypertension and associated vascular dementia in rats. ( Liu, TH; Tsai, TY, 2016)
"Because hypertension is characterized by arterial remodeling, we hypothesized that TG activity, expression, and functionality would be increased in the aorta, but not in the vena cava (which does not undergo remodeling), from hypertensive rats relative to normotensive rats."1.42Transglutaminase activity is decreased in large arteries from hypertensive rats compared with normotensive controls. ( Hitomi, K; Johnson, KB; Petersen-Jones, HG; Thompson, JM; Tykocki, NR; Watts, SW, 2015)
"Hypertension was induced by injection of DOCA-salt (25 mg/kg, s."1.42Supplementation of apelin increase plasma levels of nesfatin-1 in normal and DOCA-salt hypertensive rats. ( Akcilar, R; Ayada, C; Turgut, G; Turgut, S, 2015)
"This agent could be useful for the treatment of hypertension, cardiovascular and renal disorders."1.42Pharmacological profile of CS-3150, a novel, highly potent and selective non-steroidal mineralocorticoid receptor antagonist. ( Aoki, K; Arai, K; Homma, T; Ishikawa, H; Mizuno, M; Morikawa, Y; Sada, T; Tsuruoka, H; Ubukata, N, 2015)
"We induced hypertension and hyperlipidemia in landrace pigs (n = 8) by deoxycorticosteroneacetate (DOCA, 100 mg/kg, 90-day-release subcutaneous depot) and a Western diet (WD) containing high amounts of salt, fat, cholesterol, and sugar for 12 wk."1.42A porcine model of hypertensive cardiomyopathy: implications for heart failure with preserved ejection fraction. ( Alogna, A; Casadei, B; Eller, K; Eller, P; Hamdani, N; Höfler, G; Kirsch, A; Linke, WA; Maechler, H; Manninger, M; Pieske, BM; Post, H; Reilly, S; Schauer, S; Schwarzl, M; Seiler, S; Steendijk, P; Verderber, J; Zirngast, B; Zweiker, D, 2015)
" In order to identify pharmacokinetic changes (mainly non-renal clearance, CLNR) in 16-week-old SHRs due to hereditary characteristics and/or neither the hypertensive state itself, we reviewed the pharmacokinetics of drugs in 6- (blood pressure within a normotensive range) and 16-week-old SHRs and 16-week-old DOCA-salt rats compared with respective control rats."1.40Pharmacokinetics of drugs in spontaneously or secondary hypertensive rats. ( Lee, YS; Oh, E; Yang, S, 2014)
"Spironolactone treatment prevented Th17 cell activation and increased numbers of forkhead box P3-positive cells relative to DOCA-salt rats."1.40Spironolactone decreases DOCA-salt-induced organ damage by blocking the activation of T helper 17 and the downregulation of regulatory T lymphocytes. ( Alzamora, R; Amador, CA; Barrientos, V; Carrasco, L; Figueroa, F; González, M; Herrada, AA; Kalergis, AM; Michea, L; Peña, J; Valdés, S, 2014)
"Lacidipine-treated group (5) showed a significant reduction in elevated systolic blood pressure together with a great protection of ALT and SOD enzymes from the destructive effects of irradiation and hypertension."1.39Possible hepatoprotective effects of lacidipine in irradiated DOCA-salt hypertensive albino rats. ( Kamal, SM, 2013)

Research

Studies (89)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's67 (75.28)24.3611
2020's22 (24.72)2.80

Authors

AuthorsStudies
Abrams, RPM1
Yasgar, A1
Teramoto, T1
Lee, MH1
Dorjsuren, D1
Eastman, RT1
Malik, N1
Zakharov, AV1
Li, W2
Bachani, M1
Brimacombe, K1
Steiner, JP1
Hall, MD1
Balasubramanian, A1
Jadhav, A1
Padmanabhan, R1
Simeonov, A1
Nath, A1
Robles-Vera, I1
de la Visitación, N1
Toral, M1
Sánchez, M1
Romero, M1
Gómez-Guzmán, M1
Vargas, F1
Duarte, J1
Jiménez, R1
Bal, NB6
Bostanci, A1
Sadi, G5
Dönmez, MO1
Uludag, MO4
Demirel-Yilmaz, E6
Benson, LN1
Liu, Y3
Wang, X1
Xiong, Y1
Rhee, SW1
Guo, Y1
Deck, KS1
Mora, CJ1
Li, LX1
Huang, L1
Andrews, JT1
Qin, Z1
Hoover, RS1
Ko, B1
Williams, RM1
Heller, DA1
Jaimes, EA1
Mu, S1
Thowsen, IM1
Reikvam, T1
Skogstrand, T1
Samuelsson, AM1
Müller, DN1
Tenstad, O1
Alitalo, K1
Karlsen, T1
Wiig, H1
Guy, R1
Herman, S1
Benyamini, H1
Ben-Zur, T1
Kobo, H1
Pasmanik-Chor, M1
Yaacobi, D1
Barel, E1
Yagil, C1
Yagil, Y1
Offen, D1
Han, S5
Usanmaz, SE3
Kiremitci, S3
Uludag, O2
Yao, NA1
Niazi, ZR1
Najmanová, I1
Kamagaté, M1
Said, A1
Chabert, P1
Auger, C1
Die-Kakou, H1
Schini-Kerth, V1
Atchison, DK1
O'Connor, CL1
Menon, R1
Otto, EA1
Ganesh, SK1
Wiggins, RC1
Smrcka, AV1
Bitzer, M1
Lyu, B1
Wang, W2
Ji, XY1
Ritter, JK1
Li, N1
Chen, Y1
Dale, BL1
Alexander, MR1
Xiao, L1
Ao, M1
Pandey, AK1
Smart, CD1
Davis, GK1
Madhur, MS1
Wang, F1
Sun, Y1
Luo, R1
Lu, X1
Yang, B1
Yang, T1
Fan, L1
Gao, W1
Nguyen, BV1
Jefferson, JR1
Fan, F1
Roman, RJ1
Jin, X1
Kim, WB1
Kim, MN1
Jung, WW1
Kang, HK1
Hong, EH1
Kim, YS1
Shim, WJ1
Han, HC1
Colwell, CS1
Kim, YB1
Kim, YI1
Souza-Paula, E1
Polonio, LCC1
Zochio, GP1
da Silva, KP1
Kushima, H1
Dias-Junior, CA1
Zhang, J2
Zhu, M1
Zhang, S1
Xie, S1
Gao, Y1
Wang, Y1
Nwokocha, CR1
Gordon, A1
Palacios, J1
Paredes, A1
Cifuentes, F1
Francis, S1
Watson, J1
Delgoda, R1
Nwokocha, M1
Alexander-Lindo, R1
Thompson, R1
Minott-Kates, D1
Yakubu, MA1
Wu, X1
Liu, X2
Yang, H1
Chen, Q1
Zhang, N1
Li, Y2
Du, X1
Jiang, X1
Jiang, Y1
Zhou, Z1
Yang, Z1
Souza, LA1
Cooper, SG1
Worker, CJ2
Thakore, P1
Feng Earley, Y1
Hmazzou, R2
Marc, Y2
Flahault, A1
Gerbier, R1
De Mota, N2
Llorens-Cortes, C2
Balavoine, F1
Cai, X1
Shen, Y2
Yang, Y1
Qian, L1
Cai, J1
Chi, R1
Yu, S1
Li, K1
Wei, Z1
Chen, T1
Fei, Y1
Han, Y1
Chen, X1
Liu, M1
Wang, D1
Jiang, M1
Li, YG1
van Thiel, BS1
Góes Martini, A1
Te Riet, L1
Severs, D1
Uijl, E1
Garrelds, IM1
Leijten, FPJ1
van der Pluijm, I1
Essers, J1
Qadri, F1
Alenina, N1
Bader, M1
Paulis, L1
Rajkovicova, R1
Domenig, O1
Poglitsch, M1
Danser, AHJ1
Liu, S2
Gong, MC2
Guo, Z2
Polak, A1
Harasim-Symbor, E1
Malinowska, B1
Kasacka, I1
Pędzińska-Betiuk, A1
Weresa, J2
Chabowski, A1
Perrotta, M1
Lori, A1
Carnevale, L1
Fardella, S1
Cifelli, G1
Iacobucci, R1
Mastroiacovo, F1
Iodice, D1
Pallante, F1
Storto, M1
Lembo, G1
Carnevale, D1
Mui, RK1
Fernandes, RN1
Garver, HG1
Van Rooijen, N1
Galligan, JJ1
Douma, LG1
Holzworth, MR1
Solocinski, K1
Masten, SH1
Miller, AH1
Cheng, KY1
Lynch, IJ1
Cain, BD1
Wingo, CS1
Gumz, ML1
Safaeian, L1
Emami, R1
Hajhashemi, V1
Haghighatian, Z1
Lutshumba, J1
Zhong, Y1
Hou, T1
Daugherty, A1
Lu, H1
Cassinotti, LR1
Guil, MJ2
Schöller, MI1
Navarro, MP1
Bianciotti, LG2
Vatta, MS2
Suzuki, T1
Kamio, Y1
Makino, H1
Hokamura, K1
Kimura, T1
Yamasaki, T1
Hiramatsu, H1
Umemura, K1
Namba, H1
Tian, M1
Tang, L1
Wu, Y1
Beddhu, S1
Huang, Y1
Collister, JP1
Nahey, DB1
Hartson, R1
Wiedmeyer, CE1
Banek, CT3
Osborn, JW3
Biernacki, M1
Łuczaj, W1
Jarocka-Karpowicz, I1
Ambrożewicz, E1
Toczek, M1
Skrzydlewska, E2
Dash, JR1
Mishra, SK1
Parida, S1
Singh, TU1
Choudhury, S1
Muniyappa, K1
Krishnan, SM1
Ling, YH1
Huuskes, BM1
Ferens, DM1
Saini, N1
Chan, CT1
Diep, H1
Kett, MM1
Samuel, CS1
Kemp-Harper, BK1
Robertson, AAB1
Cooper, MA1
Peter, K1
Latz, E1
Mansell, AS1
Sobey, CG1
Drummond, GR1
Vinh, A1
Lother, A2
Deng, L1
Huck, M1
Fürst, D2
Kowalski, J1
Esser, JS1
Moser, M2
Bode, C2
Hein, L2
Tuglu, MM1
Dobrzyńska, I1
Szachowicz-Petelska, B1
Figaszewski, ZA1
Slater, RE1
Strom, JG1
Methawasin, M1
Liss, M1
Gotthardt, M1
Sweitzer, N1
Granzier, HL1
Bae, EH2
Kim, IJ1
Song, JH1
Choi, HS1
Kim, CS1
Eom, GH1
Kim, I1
Cha, H1
Cho, JM1
Ma, SK1
Kim, SW2
Gauthier, MM1
Van Helden, DA1
Fink, GD1
Koizumi, T1
Taguchi, K1
Mizuta, I1
Toba, H1
Ohigashi, M1
Onishi, O1
Ikoma, K1
Miyata, S1
Nakata, T1
Tanaka, M1
Foulquier, S1
Steinbusch, HWM1
Mizuno, T1
Pitra, S1
Feng, Y3
Stern, JE1
Chugh, PK1
Gupta, M1
Agarwal, M1
Tekur, U1
Blattner, SM1
Hodgin, JB1
Nishio, M1
Wylie, SA1
Saha, J1
Soofi, AA1
Vining, C1
Randolph, A1
Herbach, N1
Wanke, R1
Atkins, KB1
Gyung Kang, H1
Henger, A1
Brakebusch, C1
Holzman, LB1
Kretzler, M1
Yang, S1
Lee, YS1
Oh, E1
Kee, HJ1
Park, S1
Lee, KE1
Suh, SH1
Jeong, MH1
Xia, H3
Sriramula, S3
Chhabra, KH1
Lazartigues, E3
Wehrwein, EA1
Novotny, M1
Swain, GM1
Parker, LM1
Esfahanian, M1
Spitsbergen, JM1
Habecker, BA1
Kreulen, DL1
Rodrigues, SF1
Almeida-Paula, LD1
Granger, DN1
Amador, CA1
Barrientos, V1
Peña, J1
Herrada, AA1
González, M1
Valdés, S1
Carrasco, L1
Alzamora, R1
Figueroa, F1
Kalergis, AM1
Michea, L1
Kamal, SM1
Lin, JW1
Tsai, CC1
Chen, LJ1
Niu, HS1
Chang, CK1
Niu, CS1
Ighodaro, I1
Eric, OK1
Adebayo, O1
Hernandez, ME1
Hayward, LF1
Zhang, Q1
Tan, Y1
Xu, P1
de Queiroz, TM1
Johnson, T1
Mungrue, IN1
Grigson, PS1
Colechio, EM1
Power, ML1
Schulkin, J1
Norgren, R1
Ruan, CC1
Ge, Q1
Li, XD1
Chen, DR1
Ji, KD1
Wu, YJ1
Sheng, LJ1
Yan, C1
Zhu, DL1
Gao, PJ1
Petersen-Jones, HG1
Johnson, KB1
Hitomi, K1
Tykocki, NR1
Thompson, JM1
Watts, SW1
Akcilar, R1
Ayada, C1
Turgut, G1
Turgut, S2
Abramoff, T1
Morales, VP1
Hope, SI1
Höcht, C1
Dai, SY1
Peng, W1
Zhang, YP1
Li, JD1
Sun, XF1
Jo, F1
Jo, H1
Hilzendeger, AM2
Thompson, AP1
Cassell, MD1
Rutkowski, DT1
Davisson, RL1
Grobe, JL2
Sigmund, CD2
Liu, J1
Hammond, SL1
Tjalkens, RB1
Saifudeen, Z1
Liu, CT1
Chien, SP1
Hsu, DZ1
Periasamy, S1
Liu, MY1
Mohammed-Ali, Z1
Cruz, GL1
Lu, C1
Carlisle, RE1
Werner, KE1
Ask, K1
Dickhout, JG1
Arai, K1
Homma, T1
Morikawa, Y1
Ubukata, N1
Tsuruoka, H1
Aoki, K1
Ishikawa, H1
Mizuno, M1
Sada, T1
de Almeida, PW1
Melo, MB1
Lima, Rde F1
Gavioli, M1
Santiago, NM1
Greco, L1
Jesus, IC1
Nocchi, E1
Parreira, A1
Alves, MN1
Mitraud, L1
Resende, RR1
Campagnole-Santos, MJ1
Dos Santos, RA1
Guatimosim, S1
Sun, GQ1
Li, YB1
Du, B1
Meng, Y1
Jabaris, SS1
Sumathy, H1
Girish, R1
Narayanan, S1
Sugumar, M1
Saravana Babu, C1
Thanikachalam, S1
Thanikachalam, M1
Zhao, Q1
Wang, H1
Schwarzl, M1
Hamdani, N1
Seiler, S1
Alogna, A1
Manninger, M1
Reilly, S1
Zirngast, B1
Kirsch, A1
Steendijk, P1
Verderber, J1
Zweiker, D1
Eller, P1
Höfler, G1
Schauer, S1
Eller, K1
Maechler, H1
Pieske, BM1
Linke, WA1
Casadei, B1
Post, H1
Rathee, JS1
Patro, BS1
Brown, L1
Chattopadhyay, S1
Bergemann, S1
Gilsbach, R1
Grahammer, F1
Huber, TB1
Hilgendorf, I1
Ketsawatsomkron, P1
Keen, HL1
Davis, DR1
Lu, KT1
Stump, M1
De Silva, TM1
Faraci, FM1
Silva, GC1
Silva, JF1
Diniz, TF1
Lemos, VS1
Cortes, SF1
Batchu, N1
Hughson, A1
Wadosky, KM1
Morrell, CN1
Fowell, DJ1
Korshunov, VA1
Liu, TH1
Tsai, TY1
Knuepfer, MM1
Foss, JD1
Fiege, JK1
Asirvatham-Jeyaraj, N1
Van Helden, D1
Shimizu, Y1
Marques, FZ1
Nelson, E1
Chu, PY1
Horlock, D1
Fiedler, A1
Ziemann, M1
Tan, JK1
Kuruppu, S1
Rajapakse, NW1
El-Osta, A1
Mackay, CR1
Kaye, DM1
Cheng, MC1
Pan, TM1
Kursunluoglu-Akcilar, R1
Kilic-Toprak, E1
Kilic-Erkek, O1
Bor-Kucukatay, M1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effect of Innovative Natural Dietary Formulation on Primary Hypertension and the Underlying Mechanism of Gut Microbiome Restoration: Pilot Study[NCT04403347]Early Phase 190 participants (Anticipated)Interventional2021-07-08Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

89 other studies available for desoxycorticosterone acetate and Disease Models, Animal

ArticleYear
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
    Proceedings of the National Academy of Sciences of the United States of America, 2020, 12-08, Volume: 117, Issue:49

    Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr

2020
Changes in Gut Microbiota Induced by Doxycycline Influence in Vascular Function and Development of Hypertension in DOCA-Salt Rats.
    Nutrients, 2021, Aug-26, Volume: 13, Issue:9

    Topics: Animals; Anti-Bacterial Agents; Desoxycorticosterone Acetate; Disease Models, Animal; Doxycycline; E

2021
Resveratrol and regular exercise may attenuate hypertension-induced cardiac dysfunction through modulation of cellular stress responses.
    Life sciences, 2022, May-01, Volume: 296

    Topics: Animals; Desoxycorticosterone Acetate; Disease Models, Animal; Endoplasmic Reticulum Stress; Gene Ex

2022
The IFNγ-PDL1 Pathway Enhances CD8T-DCT Interaction to Promote Hypertension.
    Circulation research, 2022, 05-13, Volume: 130, Issue:10

    Topics: Animals; CD8-Positive T-Lymphocytes; Desoxycorticosterone Acetate; Disease Models, Animal; Hypertens

2022
Genetic Engineering of Lymphangiogenesis in Skin Does Not Affect Blood Pressure in Mouse Models of Salt-Sensitive Hypertension.
    Hypertension (Dallas, Tex. : 1979), 2022, Volume: 79, Issue:11

    Topics: Animals; Blood Pressure; Desoxycorticosterone; Desoxycorticosterone Acetate; Disease Models, Animal;

2022
Mesenchymal Stem Cell-Derived Extracellular Vesicles as Proposed Therapy in a Rat Model of Cerebral Small Vessel Disease.
    International journal of molecular sciences, 2022, Sep-23, Volume: 23, Issue:19

    Topics: Animals; Anti-Inflammatory Agents; Cerebral Small Vessel Diseases; Desoxycorticosterone Acetate; Dis

2022
Activation of Liver X Receptors by GW3965 Attenuated Deoxycorticosterone Acetate-Salt Hypertension-Induced Cardiac Functional and Structural Changes.
    Journal of cardiovascular pharmacology, 2019, Volume: 74, Issue:2

    Topics: Animals; Apoptosis; Benzoates; Benzylamines; Blood Pressure; Desoxycorticosterone Acetate; Disease M

2019
Hypertension-induced cardiac impairment is reversed by the inhibition of endoplasmic reticulum stress.
    The Journal of pharmacy and pharmacology, 2019, Volume: 71, Issue:12

    Topics: Animals; Apoptosis; Blood Pressure; Calcium; Desoxycorticosterone Acetate; Disease Models, Animal; E

2019
Reversal of deleterious effect of hypertension on the liver by inhibition of endoplasmic reticulum stress.
    Molecular biology reports, 2020, Volume: 47, Issue:3

    Topics: Animals; Blood Pressure; Desoxycorticosterone Acetate; Disease Models, Animal; Endoplasmic Reticulum

2020
Preventive Beneficial Effect of an Aqueous Extract of Phyllanthus amarus Schum. and Thonn. (Euphorbiaceae) on DOCA-Salt-Induced Hypertension, Cardiac Hypertrophy and Dysfunction, and Endothelial Dysfunction in Rats.
    Journal of cardiovascular pharmacology, 2020, Volume: 75, Issue:6

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Cyclooxygenase 2; Desoxycorticosterone Acetate; Di

2020
Hypertension induces glomerulosclerosis in phospholipase C-ε1 deficiency.
    American journal of physiology. Renal physiology, 2020, 05-01, Volume: 318, Issue:5

    Topics: Albuminuria; Animals; Blood Pressure; Desoxycorticosterone Acetate; Disease Models, Animal; Female;

2020
Detrimental role of sphingosine kinase 1 in kidney damage in DOCA-salt hypertensive model: evidence from knockout mice.
    BMC nephrology, 2020, 05-11, Volume: 21, Issue:1

    Topics: Actins; Albuminuria; Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Blotting, Wes

2020
Class switching and high-affinity immunoglobulin G production by B cells is dispensable for the development of hypertension in mice.
    Cardiovascular research, 2021, 03-21, Volume: 117, Issue:4

    Topics: Angiotensin II; Animals; Antibody Affinity; Aorta; Blood Pressure; Cells, Cultured; Cytidine Deamina

2021
COX-2-independent activation of renal (pro)renin receptor contributes to DOCA-salt hypertension in rats.
    American journal of physiology. Renal physiology, 2020, 10-01, Volume: 319, Issue:4

    Topics: Animals; Blood Pressure; Cardiomegaly; Cyclooxygenase 2; Desoxycorticosterone Acetate; Disease Model

2020
Impaired renal hemodynamics and glomerular hyperfiltration contribute to hypertension-induced renal injury.
    American journal of physiology. Renal physiology, 2020, 10-01, Volume: 319, Issue:4

    Topics: Animals; Arterioles; Blood Pressure; Calmodulin-Binding Proteins; Desoxycorticosterone Acetate; Dise

2020
Oestrogen inhibits salt-dependent hypertension by suppressing GABAergic excitation in magnocellular AVP neurons.
    Cardiovascular research, 2021, 08-29, Volume: 117, Issue:10

    Topics: Animals; Antihypertensive Agents; Arginine Vasopressin; Basal Nucleus of Meynert; Blood Pressure; De

2021
Anticontractile Effect of Perivascular Adipose Tissue But Not of Endothelium Is Enhanced by Hydrogen Sulfide Stimulation in Hypertensive Pregnant Rat Aortae.
    Journal of cardiovascular pharmacology, 2020, Volume: 76, Issue:6

    Topics: Adaptation, Physiological; Adipose Tissue; Animals; Aorta, Thoracic; Desoxycorticosterone Acetate; D

2020
Triptolide attenuates renal damage by limiting inflammatory responses in DOCA-salt hypertension.
    International immunopharmacology, 2020, Volume: 89, Issue:Pt A

    Topics: Animals; Anti-Inflammatory Agents; Cell Adhesion Molecules; Cytokines; Desoxycorticosterone Acetate;

2020
Hypotensive and antihypertensive effects of an aqueous extract from Guinep fruit (Melicoccus bijugatus Jacq) in rats.
    Scientific reports, 2020, 10-29, Volume: 10, Issue:1

    Topics: Animals; Antihypertensive Agents; Desoxycorticosterone Acetate; Disease Models, Animal; Endothelium,

2020
P-Selectin Glycoprotein Ligand-1 Deficiency Protects Against Aortic Aneurysm Formation Induced by DOCA Plus Salt.
    Cardiovascular drugs and therapy, 2022, Volume: 36, Issue:1

    Topics: Animals; Aortic Aneurysm; Cell Adhesion; Cell Movement; Cells, Cultured; Desoxycorticosterone Acetat

2022
Use of chlorisondamine to assess the neurogenic contribution to blood pressure in mice: An evaluation of method.
    Physiological reports, 2021, Volume: 9, Issue:3

    Topics: Animals; Blood Pressure; Cardiac Output; Cardiovascular System; Chlorisondamine; Desoxycorticosteron

2021
Brain ACE2 activation following brain aminopeptidase A blockade by firibastat in salt-dependent hypertension.
    Clinical science (London, England : 1979), 2021, 03-26, Volume: 135, Issue:6

    Topics: Angiotensin III; Angiotensin-Converting Enzyme 2; Animals; Antihypertensive Agents; Brain; Desoxycor

2021
Effects of firibastat in combination with enalapril and hydrochlorothiazide on blood pressure and vasopressin release in hypertensive DOCA-salt rats.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2021, Volume: 140

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Desoxycorticosterone Acetate; Dis

2021
Renal Denervation by Noninvasive Stereotactic Radiotherapy Induces Persistent Reduction of Sympathetic Activity in a Hypertensive Swine Model.
    Journal of the American Heart Association, 2021, 08-17, Volume: 10, Issue:16

    Topics: Animals; Blood Pressure; Desoxycorticosterone Acetate; Disease Models, Animal; Female; Hypertension;

2021
Brain Renin-Angiotensin System: Does It Exist?
    Hypertension (Dallas, Tex. : 1979), 2017, Volume: 69, Issue:6

    Topics: Amides; Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Blood-Brain Barrier; Brain; Desoxy

2017
A New Mouse Model for Introduction of Aortic Aneurysm by Implantation of Deoxycorticosterone Acetate Pellets or Aldosterone Infusion in the Presence of High Salt.
    Methods in molecular biology (Clifton, N.J.), 2017, Volume: 1614

    Topics: Aldosterone; Animals; Aortic Aneurysm; Blood Pressure Determination; Desoxycorticosterone Acetate; D

2017
The effects of chronic FAAH inhibition on myocardial lipid metabolism in normotensive and DOCA-salt hypertensive rats.
    Life sciences, 2017, Aug-15, Volume: 183

    Topics: Amidohydrolases; Animals; Benzamides; Blood Pressure; Carbamates; Chromatography, Gas; Chromatograph

2017
Deoxycorticosterone acetate-salt hypertension activates placental growth factor in the spleen to couple sympathetic drive and immune system activation.
    Cardiovascular research, 2018, Mar-01, Volume: 114, Issue:3

    Topics: Animals; Blood Pressure; Desoxycorticosterone Acetate; Disease Models, Animal; Ganglia, Sympathetic;

2018
Macrophage-dependent impairment of α
    American journal of physiology. Heart and circulatory physiology, 2018, 04-01, Volume: 314, Issue:4

    Topics: Adrenergic Fibers; Animals; Arterial Pressure; Calcium Channels, N-Type; Calcium Signaling; Desoxyco

2018
Renal Na-handling defect associated with PER1-dependent nondipping hypertension in male mice.
    American journal of physiology. Renal physiology, 2018, 06-01, Volume: 314, Issue:6

    Topics: Animals; Blood Pressure; Circadian Rhythm; Desoxycorticosterone Acetate; Disease Models, Animal; Epi

2018
Antihypertensive and antioxidant effects of protocatechuic acid in deoxycorticosterone acetate-salt hypertensive rats.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 100

    Topics: Animals; Antihypertensive Agents; Antioxidants; Blood Pressure; Desoxycorticosterone Acetate; Diseas

2018
Deletion of BMAL1 in Smooth Muscle Cells Protects Mice From Abdominal Aortic Aneurysms.
    Arteriosclerosis, thrombosis, and vascular biology, 2018, Volume: 38, Issue:5

    Topics: Aldosterone; Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; ARNTL Transcript

2018
Chronic Blockade of Brain Endothelin Receptor Type-A (ET
    International journal of molecular sciences, 2018, Feb-27, Volume: 19, Issue:3

    Topics: Animals; Blood Pressure; Catecholamines; Desoxycorticosterone Acetate; Disease Models, Animal; Endot

2018
Prevention Effect of Antiplatelets on Aneurysm Rupture in a Mouse Intracranial Aneurysm Model.
    Cerebrovascular diseases (Basel, Switzerland), 2018, Volume: 45, Issue:3-4

    Topics: Aneurysm, Ruptured; Animals; Aspirin; Cerebral Arteries; Cilostazol; Cyclooxygenase 2; Cyclooxygenas

2018
Adiponectin attenuates kidney injury and fibrosis in deoxycorticosterone acetate-salt and angiotensin II-induced CKD mice.
    American journal of physiology. Renal physiology, 2018, 09-01, Volume: 315, Issue:3

    Topics: Adiponectin; Angiotensin II; Animals; Cell Proliferation; Desoxycorticosterone Acetate; Disease Mode

2018
Lesion of the OVLT markedly attenuates chronic DOCA-salt hypertension in rats.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2018, 09-01, Volume: 315, Issue:3

    Topics: Animals; Arterial Pressure; Blood Pressure Monitoring, Ambulatory; Desoxycorticosterone Acetate; Dis

2018
The Effect of Long-Term Administration of Fatty Acid Amide Hydrolase Inhibitor URB597 on Oxidative Metabolism in the Heart of Rats with Primary and Secondary Hypertension.
    Molecules (Basel, Switzerland), 2018, Sep-14, Volume: 23, Issue:9

    Topics: Amidohydrolases; Animals; Benzamides; Carbamates; Desoxycorticosterone Acetate; Disease Models, Anim

2018
TRPV4 activation in rat carotid artery in DOCA hypertension involves eNOS and endothelium-derived contractile factor (EDCF).
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2019, Volume: 41, Issue:6

    Topics: Animals; Blood Pressure; Carotid Artery, Common; Desoxycorticosterone Acetate; Disease Models, Anima

2019
Pharmacological inhibition of the NLRP3 inflammasome reduces blood pressure, renal damage, and dysfunction in salt-sensitive hypertension.
    Cardiovascular research, 2019, 03-15, Volume: 115, Issue:4

    Topics: Albuminuria; Animals; Anti-Inflammatory Agents; Antihypertensive Agents; Blood Pressure; Chemotaxis,

2019
The effects of LXR agonist GW3965 on vascular reactivity and inflammation in hypertensive rat aorta.
    Life sciences, 2018, Nov-15, Volume: 213

    Topics: Animals; Aorta; Benzoates; Benzylamines; Blood Pressure; Cardiovascular Diseases; Desoxycorticostero

2018
Endothelial cell mineralocorticoid receptors oppose VEGF-induced gene expression and angiogenesis.
    The Journal of endocrinology, 2019, 01-01, Volume: 240, Issue:1

    Topics: Aldosterone; Animals; Aorta; Cells, Cultured; Desoxycorticosterone Acetate; Disease Models, Animal;

2019
Inhibition of endoplasmic reticulum stress protected DOCA-salt hypertension-induced vascular dysfunction.
    Vascular pharmacology, 2019, Volume: 113

    Topics: Animals; Antihypertensive Agents; Aorta, Thoracic; Apoptosis; Blood Pressure; Calcium; Cell Prolifer

2019
Changes in physicochemical properties of kidney cells membrane as a consequence of hypertension and treatment of hypertensive rats with FAAH inhibitor.
    Chemico-biological interactions, 2019, Feb-01, Volume: 299

    Topics: Amidohydrolases; Animals; Benzamides; Carbamates; Cell Membrane; Chromatography, High Pressure Liqui

2019
Metformin improves diastolic function in an HFpEF-like mouse model by increasing titin compliance.
    The Journal of general physiology, 2019, 01-07, Volume: 151, Issue:1

    Topics: Animals; Desoxycorticosterone Acetate; Diastole; Disease Models, Animal; Heart Failure; Heart Ventri

2019
Renoprotective Effect of the Histone Deacetylase Inhibitor CG200745 in DOCA-Salt Hypertensive Rats.
    International journal of molecular sciences, 2019, Jan-25, Volume: 20, Issue:3

    Topics: Actins; Albumins; Animals; Apoptosis; Biomarkers; Creatinine; Desoxycorticosterone Acetate; Disease

2019
Renal Inflammation in DOCA-Salt Hypertension.
    Hypertension (Dallas, Tex. : 1979), 2019, Volume: 73, Issue:5

    Topics: Animals; Blood Pressure; Cytokines; Desoxycorticosterone Acetate; Disease Models, Animal; Hypertensi

2019
Transiently proliferating perivascular microglia harbor M1 type and precede cerebrovascular changes in a chronic hypertension model.
    Journal of neuroinflammation, 2019, Apr-10, Volume: 16, Issue:1

    Topics: Animals; Antigens, CD; Blood Pressure; Brain; Calcium-Binding Proteins; Carboxymethylcellulose Sodiu

2019
Exacerbated effects of prorenin on hypothalamic magnocellular neuronal activity and vasopressin plasma levels during salt-sensitive hypertension.
    American journal of physiology. Heart and circulatory physiology, 2019, 09-01, Volume: 317, Issue:3

    Topics: Animals; Blood Pressure; Desoxycorticosterone Acetate; Disease Models, Animal; Hypertension; Hypotha

2019
Etoricoxib attenuates effect of antihypertensives in a rodent model of DOCA-salt induced hypertension.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2013, Volume: 35, Issue:8

    Topics: Animals; Antihypertensive Agents; Atenolol; Benzimidazoles; Benzoates; Blood Pressure; Cyclooxygenas

2013
Divergent functions of the Rho GTPases Rac1 and Cdc42 in podocyte injury.
    Kidney international, 2013, Volume: 84, Issue:5

    Topics: Actin Depolymerizing Factors; Acute Kidney Injury; Albuminuria; Animals; cdc42 GTP-Binding Protein;

2013
Pharmacokinetics of drugs in spontaneously or secondary hypertensive rats.
    Xenobiotica; the fate of foreign compounds in biological systems, 2014, Volume: 44, Issue:1

    Topics: Age Factors; Animals; Cytochrome P-450 Enzyme System; Desoxycorticosterone Acetate; Disease Models,

2014
HDAC inhibition suppresses cardiac hypertrophy and fibrosis in DOCA-salt hypertensive rats via regulation of HDAC6/HDAC8 enzyme activity.
    Kidney & blood pressure research, 2013, Volume: 37, Issue:4-5

    Topics: Animals; Cardiomegaly; Desoxycorticosterone Acetate; Disease Models, Animal; Enzyme Activation; Fibr

2013
Brain angiotensin-converting enzyme type 2 shedding contributes to the development of neurogenic hypertension.
    Circulation research, 2013, Oct-12, Volume: 113, Issue:9

    Topics: ADAM Proteins; ADAM17 Protein; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-

2013
Regional changes in cardiac and stellate ganglion norepinephrine transporter in DOCA-salt hypertension.
    Autonomic neuroscience : basic & clinical, 2013, Volume: 179, Issue:1-2

    Topics: Animals; Desoxycorticosterone Acetate; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; He

2013
Synergistic effects of high blood cholesterol and hypertension on leukocyte and platelet recruitment in the cerebral microcirculation.
    Hypertension (Dallas, Tex. : 1979), 2014, Volume: 63, Issue:4

    Topics: Animals; Apolipoproteins E; Blood Platelets; Cell Adhesion; Cell Movement; Cerebrovascular Circulati

2014
Spironolactone decreases DOCA-salt-induced organ damage by blocking the activation of T helper 17 and the downregulation of regulatory T lymphocytes.
    Hypertension (Dallas, Tex. : 1979), 2014, Volume: 63, Issue:4

    Topics: Animals; Antibodies; Desoxycorticosterone Acetate; Disease Models, Animal; Down-Regulation; Forkhead

2014
Possible hepatoprotective effects of lacidipine in irradiated DOCA-salt hypertensive albino rats.
    Pakistan journal of biological sciences : PJBS, 2013, Nov-01, Volume: 16, Issue:21

    Topics: Alanine Transaminase; Animals; Blood Pressure; Desoxycorticosterone Acetate; Dihydropyridines; Disea

2013
Characterization of musclin as a new target for treatment of hypertension.
    BioMed research international, 2014, Volume: 2014

    Topics: Animals; Calcium; Desoxycorticosterone Acetate; Disease Models, Animal; Gene Expression Regulation;

2014
Interactions of PPAR α and GLUT4 in DOCA/salt-induced renal injury in mice.
    Nigerian journal of physiological sciences : official publication of the Physiological Society of Nigeria, 2013, Dec-20, Volume: 28, Issue:2

    Topics: Animals; Desoxycorticosterone Acetate; Disease Models, Animal; Fenofibrate; Glucose Transporter Type

2013
Effect of DOCA/salt hypertension on CRF expression in the amygdala and the autonomic stress response in conscious rats.
    Autonomic neuroscience : basic & clinical, 2014, Volume: 185

    Topics: Amygdala; Animals; Autonomic Nervous System; Baroreflex; Blood Pressure; Consciousness; Corticotropi

2014
[Effect of inhibiting brain reactive oxygen species on sympathetic nerve activity in DOCA-salt hypertensive rats].
    Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2014, Volume: 34, Issue:11

    Topics: Animals; Antioxidants; Arterial Pressure; Blood Pressure; Brain; Cyclic N-Oxides; Desoxycorticostero

2014
Brain-targeted angiotensin-converting enzyme 2 overexpression attenuates neurogenic hypertension by inhibiting cyclooxygenase-mediated inflammation.
    Hypertension (Dallas, Tex. : 1979), 2015, Volume: 65, Issue:3

    Topics: Angiotensin-Converting Enzyme 2; Animals; Antioxidants; Brain; Cyclooxygenase 1; Cyclooxygenase 2; D

2015
Brain ACE2 overexpression reduces DOCA-salt hypertension independently of endoplasmic reticulum stress.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2015, Mar-01, Volume: 308, Issue:5

    Topics: Angiotensin-Converting Enzyme 2; Animals; Biomarkers; Blood Pressure; Brain; Desoxycorticosterone Ac

2015
Parabrachial lesions in rats disrupt sodium appetite induced by furosemide but not by calcium deprivation.
    Physiology & behavior, 2015, Mar-01, Volume: 140

    Topics: Analysis of Variance; Animals; Appetite; Calcium; Calcium Chloride; Conditioning, Psychological; Des

2015
Complement-mediated macrophage polarization in perivascular adipose tissue contributes to vascular injury in deoxycorticosterone acetate-salt mice.
    Arteriosclerosis, thrombosis, and vascular biology, 2015, Volume: 35, Issue:3

    Topics: 3T3-L1 Cells; Adipocytes; Adipose Tissue; Animals; Bone Marrow Transplantation; Cell Communication;

2015
Transglutaminase activity is decreased in large arteries from hypertensive rats compared with normotensive controls.
    American journal of physiology. Heart and circulatory physiology, 2015, Mar-15, Volume: 308, Issue:6

    Topics: Animals; Aorta, Thoracic; Cells, Cultured; Desoxycorticosterone Acetate; Disease Models, Animal; Dow

2015
Supplementation of apelin increase plasma levels of nesfatin-1 in normal and DOCA-salt hypertensive rats.
    Bratislavske lekarske listy, 2015, Volume: 116, Issue:2

    Topics: Animals; Apelin; Calcium-Binding Proteins; Desoxycorticosterone Acetate; Disease Models, Animal; DNA

2015
Involvement of endothelins in deoxycorticosterone acetate-salt hypertension through the modulation of noradrenergic transmission in the rat posterior hypothalamus.
    Experimental physiology, 2015, Volume: 100, Issue:6

    Topics: Adrenergic Neurons; Animals; Blood Pressure; Desoxycorticosterone Acetate; Disease Models, Animal; E

2015
Brain endogenous angiotensin II receptor type 2 (AT2-R) protects against DOCA/salt-induced hypertension in female rats.
    Journal of neuroinflammation, 2015, Mar-08, Volume: 12

    Topics: Analysis of Variance; Angiotensin II Type 2 Receptor Blockers; Animals; Blood Pressure; Brain; Cytok

2015
Brain endoplasmic reticulum stress mechanistically distinguishes the saline-intake and hypertensive response to deoxycorticosterone acetate-salt.
    Hypertension (Dallas, Tex. : 1979), 2015, Volume: 65, Issue:6

    Topics: Analysis of Variance; Animals; Blood Pressure; Brain; Desoxycorticosterone Acetate; Disease Models,

2015
Angiotensin II regulates brain (pro)renin receptor expression through activation of cAMP response element-binding protein.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2015, Jul-15, Volume: 309, Issue:2

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; A

2015
Curative effect of sesame oil in a rat model of chronic kidney disease.
    Nephrology (Carlton, Vic.), 2015, Volume: 20, Issue:12

    Topics: Albuminuria; Animals; Antioxidants; Collagen; Desoxycorticosterone Acetate; Disease Models, Animal;

2015
Development of a Model of Chronic Kidney Disease in the C57BL/6 Mouse with Properties of Progressive Human CKD.
    BioMed research international, 2015, Volume: 2015

    Topics: Angiotensin II; Animals; Desoxycorticosterone Acetate; Disease Models, Animal; Disease Progression;

2015
Pharmacological profile of CS-3150, a novel, highly potent and selective non-steroidal mineralocorticoid receptor antagonist.
    European journal of pharmacology, 2015, Aug-15, Volume: 761

    Topics: Administration, Oral; Adrenalectomy; Aldosterone; Animals; Antihypertensive Agents; Binding, Competi

2015
Beneficial effects of angiotensin-(1-7) against deoxycorticosterone acetate-induced diastolic dysfunction occur independently of changes in blood pressure.
    Hypertension (Dallas, Tex. : 1979), 2015, Volume: 66, Issue:2

    Topics: Angiotensin I; Animals; Blood Pressure; Calcium; Calcium Signaling; Desoxycorticosterone Acetate; Di

2015
Resveratrol via activation of AMPK lowers blood pressure in DOCA-salt hypertensive mice.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2015, Volume: 37, Issue:8

    Topics: AMP-Activated Protein Kinases; Animals; Anticarcinogenic Agents; Blood Pressure; Desoxycorticosteron

2015
Phosphodiesterase-4 inhibitors ameliorates cognitive deficits in deoxycorticosterone acetate induced hypertensive rats via cAMP/CREB signaling system.
    Brain research, 2015, Oct-05, Volume: 1622

    Topics: Adrenergic alpha-2 Receptor Agonists; Aminopyridines; Animals; Antihypertensive Agents; Benzamides;

2015
PGC-1α overexpression suppresses blood pressure elevation in DOCA-salt hypertensive mice.
    Bioscience reports, 2015, May-21, Volume: 35, Issue:3

    Topics: Animals; Aorta; Blood Pressure; Cells, Cultured; Desoxycorticosterone Acetate; Disease Models, Anima

2015
A porcine model of hypertensive cardiomyopathy: implications for heart failure with preserved ejection fraction.
    American journal of physiology. Heart and circulatory physiology, 2015, Volume: 309, Issue:9

    Topics: Animals; Cardiomyopathies; Connectin; Desoxycorticosterone Acetate; Diet, Western; Dilatation, Patho

2015
Mechanism of the anti-hypertensive property of the naturally occurring phenolic, malabaricone C in DOCA-salt rats.
    Free radical research, 2016, Volume: 50, Issue:1

    Topics: Animals; Antihypertensive Agents; Antioxidants; Aorta; Desoxycorticosterone Acetate; Disease Models,

2016
Deoxycorticosterone Acetate/Salt-Induced Cardiac But Not Renal Injury Is Mediated By Endothelial Mineralocorticoid Receptors Independently From Blood Pressure.
    Hypertension (Dallas, Tex. : 1979), 2016, Volume: 67, Issue:1

    Topics: Animals; Blood Pressure; Cells, Cultured; Desoxycorticosterone Acetate; Disease Models, Animal; Endo

2016
Protective Role for Tissue Inhibitor of Metalloproteinase-4, a Novel Peroxisome Proliferator-Activated Receptor-γ Target Gene, in Smooth Muscle in Deoxycorticosterone Acetate-Salt Hypertension.
    Hypertension (Dallas, Tex. : 1979), 2016, Volume: 67, Issue:1

    Topics: Animals; Blood Pressure; Desoxycorticosterone Acetate; Disease Models, Animal; DNA; Gene Expression

2016
Endothelial dysfunction in DOCA-salt-hypertensive mice: role of neuronal nitric oxide synthase-derived hydrogen peroxide.
    Clinical science (London, England : 1979), 2016, 06-01, Volume: 130, Issue:11

    Topics: Animals; Desoxycorticosterone Acetate; Disease Models, Animal; Endothelium, Vascular; Hydrogen Perox

2016
Role of Axl in T-Lymphocyte Survival in Salt-Dependent Hypertension.
    Arteriosclerosis, thrombosis, and vascular biology, 2016, Volume: 36, Issue:8

    Topics: Adoptive Transfer; Animals; Apoptosis; Axl Receptor Tyrosine Kinase; Blood Pressure; CD4-Positive T-

2016
Effects of equol on deoxycorticosterone acetate salt-induced hypertension and associated vascular dementia in rats.
    Food & function, 2016, Aug-10, Volume: 7, Issue:8

    Topics: Acetylcholinesterase; Animals; Blood Pressure; Body Weight; Brain; Catalase; Dementia, Vascular; Des

2016
Resting Afferent Renal Nerve Discharge and Renal Inflammation: Elucidating the Role of Afferent and Efferent Renal Nerves in Deoxycorticosterone Acetate Salt Hypertension.
    Hypertension (Dallas, Tex. : 1979), 2016, Volume: 68, Issue:6

    Topics: Animals; Desoxycorticosterone Acetate; Disease Models, Animal; Hypertension; Kidney; Male; Nephritis

2016
High-Fiber Diet and Acetate Supplementation Change the Gut Microbiota and Prevent the Development of Hypertension and Heart Failure in Hypertensive Mice.
    Circulation, 2017, Mar-07, Volume: 135, Issue:10

    Topics: Animals; Bacteria; Blood Pressure; Desoxycorticosterone Acetate; Dietary Fiber; Dietary Supplements;

2017
Prevention of hypertension-induced vascular dementia by Lactobacillus paracasei subsp. paracasei NTU 101-fermented products.
    Pharmaceutical biology, 2017, Volume: 55, Issue:1

    Topics: Animals; Aorta; Behavior, Animal; Blood Pressure; Cultured Milk Products; Cytokines; Dementia; Desox

2017
Apelin-induced hemorheological alterations in DOCA-salt hypertensive rats.
    Clinical hemorheology and microcirculation, 2014, Volume: 56, Issue:1

    Topics: Animals; Apelin; Desoxycorticosterone Acetate; Disease Models, Animal; Erythrocyte Aggregation; Eryt

2014