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desoxycorticosterone acetate and Cardiomegaly

desoxycorticosterone acetate has been researched along with Cardiomegaly in 8 studies

Desoxycorticosterone Acetate: The 21-acetate derivative of desoxycorticosterone.

Cardiomegaly: Enlargement of the HEART, usually indicated by a cardiothoracic ratio above 0.50. Heart enlargement may involve the right, the left, or both HEART VENTRICLES or HEART ATRIA. Cardiomegaly is a nonspecific symptom seen in patients with chronic systolic heart failure (HEART FAILURE) or several forms of CARDIOMYOPATHIES.

Research Excerpts

ExcerptRelevanceReference
" Desoxycorticosterone acetate (DCA) and NaCl, in the dosage employed in normal rats, caused renal and cardiac hypertrophy, characteristic changes in the renal tubular epithelium, atrophic changes in the subcapsular zone of the adrenal cortex, and serum electrolyte changes characterized by a rise in sodium and fall in potassium."3.63DESOXYCORTICOSTERONE ACETATE : THE POTENTIATION OF ITS ACTIVITY BY SODIUM CHLORIDE. ( Knowlton, AI; Loeb, EN; Seegal, BC; Stoerk, HC, 1947)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19901 (12.50)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (50.00)24.3611
2020's3 (37.50)2.80

Authors

AuthorsStudies
Wu, H2
Tang, LX2
Wang, XM2
Li, LP2
Chen, XK2
He, YJ2
Yang, DZ2
Shi, Y2
Shou, JL2
Zhang, ZS2
Wang, L2
Lu, BJ2
An, SM2
Zeng, CY2
Wang, WE2
Samuelsson, AM1
Bartolomaeus, TUP1
Anandakumar, H1
Thowsen, I1
Nikpey, E1
Han, J1
Marko, L1
Finne, K1
Tenstad, O1
Eckstein, J1
Berndt, N1
Kühne, T1
Kedziora, S1
Sultan, I1
Skogstrand, T1
Karlsen, TV1
Nurmi, H1
Forslund, SK1
Bollano, E1
Alitalo, K1
Muller, DN1
Wiig, H1
Cao, HJ1
Fang, J1
Zhang, YL2
Zou, LX1
Han, X1
Yang, J1
Yan, X1
Li, PB1
Wang, HX2
Guo, SB1
Li, HH2
Wang, F1
Sun, Y1
Luo, R1
Lu, X1
Yang, B1
Yang, T1
Alogna, A1
Schwarzl, M1
Manninger, M1
Hamdani, N1
Zirngast, B1
Kloth, B1
Steendijk, P1
Verderber, J1
Zweiker, D1
Westermann, D1
Blankenberg, S1
Maechler, H1
Tschöpe, C1
Linke, WA1
Marsche, G1
Pieske, BM1
Post, H1
Liu, S1
Liu, LX1
Lai, S1
Xie, YP1
Li, NN1
Xia, YL1
Liu, Y1
Kee, HJ1
Bae, EH1
Park, S1
Lee, KE1
Suh, SH1
Kim, SW1
Jeong, MH1
Knowlton, AI1
Loeb, EN1
Stoerk, HC1
Seegal, BC1

Other Studies

8 other studies available for desoxycorticosterone acetate and Cardiomegaly

ArticleYear
Porcupine inhibitor CGX1321 alleviates heart failure with preserved ejection fraction in mice by blocking WNT signaling.
    Acta pharmacologica Sinica, 2023, Volume: 44, Issue:6

    Topics: Animals; Cardiomegaly; Cardiomyopathies; Desoxycorticosterone Acetate; Fibrosis; Heart Failure; Mice

2023
Porcupine inhibitor CGX1321 alleviates heart failure with preserved ejection fraction in mice by blocking WNT signaling.
    Acta pharmacologica Sinica, 2023, Volume: 44, Issue:6

    Topics: Animals; Cardiomegaly; Cardiomyopathies; Desoxycorticosterone Acetate; Fibrosis; Heart Failure; Mice

2023
Porcupine inhibitor CGX1321 alleviates heart failure with preserved ejection fraction in mice by blocking WNT signaling.
    Acta pharmacologica Sinica, 2023, Volume: 44, Issue:6

    Topics: Animals; Cardiomegaly; Cardiomyopathies; Desoxycorticosterone Acetate; Fibrosis; Heart Failure; Mice

2023
Porcupine inhibitor CGX1321 alleviates heart failure with preserved ejection fraction in mice by blocking WNT signaling.
    Acta pharmacologica Sinica, 2023, Volume: 44, Issue:6

    Topics: Animals; Cardiomegaly; Cardiomyopathies; Desoxycorticosterone Acetate; Fibrosis; Heart Failure; Mice

2023
VEGF-B hypertrophy predisposes to transition from diastolic to systolic heart failure in hypertensive rats.
    Cardiovascular research, 2023, 07-04, Volume: 119, Issue:7

    Topics: Animals; Cardiomegaly; Desoxycorticosterone Acetate; Heart Failure; Heart Failure, Systolic; Hyperte

2023
Genetic ablation and pharmacological inhibition of immunosubunit β5i attenuates cardiac remodeling in deoxycorticosterone-acetate (DOCA)-salt hypertensive mice.
    Journal of molecular and cellular cardiology, 2019, Volume: 137

    Topics: Animals; Cardiomegaly; Chymotrypsin; Desoxycorticosterone Acetate; Fibrosis; Hypertension; Inflammat

2019
COX-2-independent activation of renal (pro)renin receptor contributes to DOCA-salt hypertension in rats.
    American journal of physiology. Renal physiology, 2020, 10-01, Volume: 319, Issue:4

    Topics: Animals; Blood Pressure; Cardiomegaly; Cyclooxygenase 2; Desoxycorticosterone Acetate; Disease Model

2020
Acute stimulation of the soluble guanylate cyclase does not impact on left ventricular capacitance in normal and hypertrophied porcine hearts in vivo.
    American journal of physiology. Heart and circulatory physiology, 2018, 09-01, Volume: 315, Issue:3

    Topics: Animals; Blood Pressure; Cardiomegaly; Connectin; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases;

2018
Cardiac Ablation of SOCS3 Aggravates DOCA-Salt-Induced Hypertrophic Remodeling by Activation of Gp130-Dependent Signaling in Mice.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2018, Volume: 47, Issue:1

    Topics: Animals; Cardiomegaly; Cytokine Receptor gp130; Desoxycorticosterone Acetate; Gene Deletion; Male; M

2018
HDAC inhibition suppresses cardiac hypertrophy and fibrosis in DOCA-salt hypertensive rats via regulation of HDAC6/HDAC8 enzyme activity.
    Kidney & blood pressure research, 2013, Volume: 37, Issue:4-5

    Topics: Animals; Cardiomegaly; Desoxycorticosterone Acetate; Disease Models, Animal; Enzyme Activation; Fibr

2013
DESOXYCORTICOSTERONE ACETATE : THE POTENTIATION OF ITS ACTIVITY BY SODIUM CHLORIDE.
    The Journal of experimental medicine, 1947, Jan-31, Volume: 85, Issue:2

    Topics: Adrenal Glands; Animals; Cardiomegaly; Desoxycorticosterone; Desoxycorticosterone Acetate; Hypertens

1947