desonide and Skin-Diseases

Desonide, a nonfluorinated topical corticosteriod, was compared with fluocinonide, a potent fluorinated steroid, in identical concentrations, in the treatment of various steroid-responsive dermatologic disorders. In treatment comparisons, the group treated with desonide showed significantly (p less than 0.05) better erythema and scaling scores after the first week than did those in the fluocinonide group, but the two week scores were not significantly different. Although 5 percent of patients treated with fluocinonide had adverse reactions, no such reactions were observed in the desonide-treated group.

Topics: Adolescent; Adult; Child; Child, Preschool; Clinical Trials as Topic; Dermatitis, Contact; Desonide; Female; Fluocinolone Acetonide; Fluocinonide; Humans; Infant; Male; Middle Aged; Pregnadienetriols; Skin Diseases; Time Factors

Cutaneous sarcoidosis is challenging to diagnose due to its many nonspecific manifestations. In this report we describe a case of cutaneous sarcoidosis in a patient presenting with multiple lesions. Diagnosis of the disease involves not only clinical and pathologic findings but also multiple exclusions.

Topics: Anti-Inflammatory Agents; Black or African American; Clobetasol; Desonide; Female; Glucocorticoids; Humans; Middle Aged; Sarcoidosis; Skin Diseases; United States

Topics: Atrophy; Desonide; Humans; Pregnadienetriols; Skin Diseases