desonide and Eczema

desonide has been researched along with Eczema* in 3 studies

Trials

1 trial(s) available for desonide and Eczema

Article	Year
Control of the bioavailability of a topical steroid; comparison of desonide creams 0.05% and 0.1% by vasoconstrictor studies and clinical trials. Clinical and experimental dermatology, 1987, Volume: 12, Issue:6 Topics: Adolescent; Adult; Aged; Biological Availability; Child; Clinical Trials as Topic; Desonide; Double-Blind Method; Eczema; Humans; Middle Aged; Pregnadienetriols; Random Allocation; Skin; Vasoconstriction	1987

Article

Year

Control of the bioavailability of a topical steroid; comparison of desonide creams 0.05% and 0.1% by vasoconstrictor studies and clinical trials.

Clinical and experimental dermatology, 1987, Volume: 12, Issue:6

Topics: Adolescent; Adult; Aged; Biological Availability; Child; Clinical Trials as Topic; Desonide; Double-Blind Method; Eczema; Humans; Middle Aged; Pregnadienetriols; Random Allocation; Skin; Vasoconstriction

1987

Other Studies

2 other study(ies) available for desonide and Eczema

Article	Year
Desonide Nanoemulsion Gel for Transdermal Absorption Drug Delivery: Pharmacodynamic and Safety Evaluation. Current drug delivery, 2023, Volume: 20, Issue:10 When administered transdermally, desonide is ineffective due to its poor solubility. As a new transdermal delivery system, nanoemulsion gel has demonstrated significant advantages for drug delivery over conventional formulations. We have established desonide nanoemulsion gel (DES NE gel) for better transdermal absorption, but its efficacy and safety still need to be evaluated. This study aims to provide additional evidence demonstrating the improved pharmacodynamics and safety of transdermal delivery of Desonide via nanoemulsion gel.. Pharmacodynamics and safety of Desonide nanoemulsion gel were evaluated using Desonate. Nanoemulsion gels may facilitate transdermal penetration of drugs by influencing the skin condition. Medium and high doses of DES NE gel significantly ameliorated the inflammation and swelling of the ear caused by dermatitis/eczema in mice. In addition, compared with DES gel, skin irritation extent did not increase.. Nanoemulsion gel can be applied to improve the efficacy of drugs with low potency or poor solubility. DES NE gel provides a higher transdermal potential than other delivery systems. In this study, it was found that nanoemulsion gel is a promising percutaneous carrier of DES. DES NE-GEL has a significant curative effect on dermatitis/eczema in a mouse model and is expected to provide a new, efficient, and low toxic preparation for clinical treatment of dermatitis/eczema through the percutaneous system. Topics: Administration, Cutaneous; Animals; Desonide; Eczema; Emulsions; Gels; Mice; Rabbits; Skin; Skin Absorption	2023
Toddler-to-mother transmission of varicella-vaccine virus: how bad is that? The Journal of pediatrics, 1997, Volume: 131, Issue:1 Pt 1 Topics: Administration, Topical; Anti-Inflammatory Agents; Chickenpox; Chickenpox Vaccine; Contraindications; Desonide; Eczema; Female; Fetal Diseases; Glucocorticoids; Herpesvirus 3, Human; Humans; Infant; Infectious Disease Transmission, Vertical; Male; Pregnancy; Pregnancy Complications, Infectious; Risk Factors; Vaccination	1997

Article

Year

Desonide Nanoemulsion Gel for Transdermal Absorption Drug Delivery: Pharmacodynamic and Safety Evaluation.

Current drug delivery, 2023, Volume: 20, Issue:10

When administered transdermally, desonide is ineffective due to its poor solubility. As a new transdermal delivery system, nanoemulsion gel has demonstrated significant advantages for drug delivery over conventional formulations. We have established desonide nanoemulsion gel (DES NE gel) for better transdermal absorption, but its efficacy and safety still need to be evaluated. This study aims to provide additional evidence demonstrating the improved pharmacodynamics and safety of transdermal delivery of Desonide via nanoemulsion gel.. Pharmacodynamics and safety of Desonide nanoemulsion gel were evaluated using Desonate. Nanoemulsion gels may facilitate transdermal penetration of drugs by influencing the skin condition. Medium and high doses of DES NE gel significantly ameliorated the inflammation and swelling of the ear caused by dermatitis/eczema in mice. In addition, compared with DES gel, skin irritation extent did not increase.. Nanoemulsion gel can be applied to improve the efficacy of drugs with low potency or poor solubility. DES NE gel provides a higher transdermal potential than other delivery systems. In this study, it was found that nanoemulsion gel is a promising percutaneous carrier of DES. DES NE-GEL has a significant curative effect on dermatitis/eczema in a mouse model and is expected to provide a new, efficient, and low toxic preparation for clinical treatment of dermatitis/eczema through the percutaneous system.

Topics: Administration, Cutaneous; Animals; Desonide; Eczema; Emulsions; Gels; Mice; Rabbits; Skin; Skin Absorption

2023

Toddler-to-mother transmission of varicella-vaccine virus: how bad is that?

The Journal of pediatrics, 1997, Volume: 131, Issue:1 Pt 1

Topics: Administration, Topical; Anti-Inflammatory Agents; Chickenpox; Chickenpox Vaccine; Contraindications; Desonide; Eczema; Female; Fetal Diseases; Glucocorticoids; Herpesvirus 3, Human; Humans; Infant; Infectious Disease Transmission, Vertical; Male; Pregnancy; Pregnancy Complications, Infectious; Risk Factors; Vaccination

1997