desmosterol and Lesch-Nyhan-Syndrome

desmosterol has been researched along with Lesch-Nyhan-Syndrome* in 1 studies

Other Studies

1 other study(ies) available for desmosterol and Lesch-Nyhan-Syndrome

Article	Year
Restoration of the conversion of desmosterol to cholesterol in L-cells after hybridization with human fibroblasts. Proceedings of the National Academy of Sciences of the United States of America, 1974, Volume: 71, Issue:1 Hybrids between different human cells (which synthesize cholesterol) and mouse cells (whose end-product of sterol synthesis is desmosterol) were analyzed for the ability to convert desmosterol to cholesterol. Conversion of [(14)C]desmosterol to cholesterol and incorporation of [(14)C]acetate into the end-product sterol were studied in the parental and hybrid cells. Concordant segregation of the conversion of desmosterol to cholesterol and the human chromosome F-20 was observed. Topics: Acetates; Animals; Carbon Radioisotopes; Cell Line; Cell Transformation, Neoplastic; Cholesterol; Chromosome Mapping; Chromosomes, Human, 19-20; Desmosterol; Female; Fibroblasts; Genes; Humans; Hybrid Cells; Karyotyping; L Cells; Lesch-Nyhan Syndrome; Male; Mice; Sex Chromosomes; Simian virus 40; Steroid Hydroxylases	1974

Article

Year

Restoration of the conversion of desmosterol to cholesterol in L-cells after hybridization with human fibroblasts.

Proceedings of the National Academy of Sciences of the United States of America, 1974, Volume: 71, Issue:1

Hybrids between different human cells (which synthesize cholesterol) and mouse cells (whose end-product of sterol synthesis is desmosterol) were analyzed for the ability to convert desmosterol to cholesterol. Conversion of [(14)C]desmosterol to cholesterol and incorporation of [(14)C]acetate into the end-product sterol were studied in the parental and hybrid cells. Concordant segregation of the conversion of desmosterol to cholesterol and the human chromosome F-20 was observed.

Topics: Acetates; Animals; Carbon Radioisotopes; Cell Line; Cell Transformation, Neoplastic; Cholesterol; Chromosome Mapping; Chromosomes, Human, 19-20; Desmosterol; Female; Fibroblasts; Genes; Humans; Hybrid Cells; Karyotyping; L Cells; Lesch-Nyhan Syndrome; Male; Mice; Sex Chromosomes; Simian virus 40; Steroid Hydroxylases

1974