desipramine has been researched along with Weight Gain in 7 studies
Desipramine: A tricyclic dibenzazepine compound that potentiates neurotransmission. Desipramine selectively blocks reuptake of norepinephrine from the neural synapse, and also appears to impair serotonin transport. This compound also possesses minor anticholinergic activity, through its affinity to muscarinic receptors.
desipramine : A dibenzoazepine consisting of 10,11-dihydro-5H-dibenzo[b,f]azepine substituted on nitrogen with a 3-(methylamino)propyl group.
Weight Gain: Increase in BODY WEIGHT over existing weight.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Three tricyclic antidepressants examined (imipramine, clomipramine and desipramine) did not seem to have the side effect of pathological weight gain in the frequency distribution pattern." | 5.07 | Changes in the frequency distribution pattern of body weight in patients with major depression. ( Kato, T; Murashita, J; Shioiri, T; Takahashi, S; Yamada, N, 1993) |
| " CUS-exposed rats showed depressive-like behavior with reduced weight gain, reduced consumption of sucrose solution, increased immobility in the forced swimming test, and hypolocomotion in an open field." | 3.78 | Effect of long-term caffeine administration on depressive-like behavior in rats exposed to chronic unpredictable stress. ( Alova, LH; Nikolov, RP; Pechlivanova, DM; Petkov, VV; Tchekalarova, JD; Yakimova, KS, 2012) |
| " In this study, we examined the interaction between prolonged exposure to either repeated restraint stress or chronic mild stress with the chronic administration of the antidepressant desipramine on two spontaneous behaviours, in which an involvement of the mesolimbic dopamine system has been suggested: novelty-induced exploratory activity and grooming." | 1.31 | Exploratory behaviour and grooming after repeated restraint and chronic mild stress: effect of desipramine. ( Carboni, V; D'Aquila, PS; Peana, AT; Serra, G, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (14.29) | 18.7374 |
| 1990's | 2 (28.57) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hibicke, M | 1 |
| Graham, MA | 1 |
| Hayslett, RL | 1 |
| Pechlivanova, DM | 1 |
| Tchekalarova, JD | 1 |
| Alova, LH | 1 |
| Petkov, VV | 1 |
| Nikolov, RP | 1 |
| Yakimova, KS | 1 |
| Gobshtis, N | 1 |
| Ben-Shabat, S | 1 |
| Fride, E | 1 |
| Szarek, BL | 1 |
| Brandt, DM | 1 |
| Shioiri, T | 1 |
| Kato, T | 1 |
| Murashita, J | 1 |
| Yamada, N | 1 |
| Takahashi, S | 1 |
| D'Aquila, PS | 1 |
| Peana, AT | 1 |
| Carboni, V | 1 |
| Serra, G | 1 |
| Fernstrom, MH | 1 |
| Kupfer, DJ | 1 |
2 trials available for desipramine and Weight Gain
| Article | Year |
|---|---|
Changes in the frequency distribution pattern of body weight in patients with major depression.
Topics: Adult; Antidepressive Agents, Tricyclic; Body Weight; Clomipramine; Depressive Disorder; Desipramine | 1993 |
Antidepressant-induced weight gain: a comparison study of four medications.
Topics: Adult; Amitriptyline; Antidepressive Agents; Depressive Disorder; Desipramine; Female; Humans; Male; | 1988 |
5 other studies available for desipramine and Weight Gain
| Article | Year |
|---|---|
Adolescent chronic restraint stress (aCRS) elicits robust depressive-like behavior in freely cycling, adult female rats without increasing anxiety-like behaviors.
Topics: Age Factors; Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Depression; Depressive Dis | 2017 |
Effect of long-term caffeine administration on depressive-like behavior in rats exposed to chronic unpredictable stress.
Topics: Administration, Oral; Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Body Temperature; | 2012 |
Antidepressant-induced undesirable weight gain: prevention with rimonabant without interference with behavioral effectiveness.
Topics: Analysis of Variance; Animals; Antidepressive Agents; Anxiety; Behavior, Animal; Desipramine; Female | 2007 |
A comparison of weight changes with fluoxetine, desipramine, and amitriptyline: a retrospective study of psychiatric inpatients.
Topics: Amitriptyline; Body Weight; Desipramine; Dose-Response Relationship, Drug; Drug Therapy, Combination | 1993 |
Exploratory behaviour and grooming after repeated restraint and chronic mild stress: effect of desipramine.
Topics: Animals; Antidepressive Agents, Tricyclic; Chronic Disease; Desipramine; Exploratory Behavior; Groom | 2000 |