desipramine has been researched along with Stuttering in 3 studies
Desipramine: A tricyclic dibenzazepine compound that potentiates neurotransmission. Desipramine selectively blocks reuptake of norepinephrine from the neural synapse, and also appears to impair serotonin transport. This compound also possesses minor anticholinergic activity, through its affinity to muscarinic receptors.
desipramine : A dibenzoazepine consisting of 10,11-dihydro-5H-dibenzo[b,f]azepine substituted on nitrogen with a 3-(methylamino)propyl group.
Stuttering: A disturbance in the normal fluency and time patterning of speech that is inappropriate for the individual's age. This disturbance is characterized by frequent repetitions or prolongations of sounds or syllables. Various other types of speech dysfluencies may also be involved including interjections, broken words, audible or silent blocking, circumlocutions, words produced with an excess of physical tension, and monosyllabic whole word repetitions. Stuttering may occur as a developmental condition in childhood or as an acquired disorder which may be associated with BRAIN INFARCTIONS and other BRAIN DISEASES. (From DSM-IV, 1994)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Clomipramine, a serotonin reuptake blocker that has been shown to be effective in treating obsessive-compulsive disorder and other unwanted repetitive, ritualized behaviors, was hypothesized to be superior to desipramine, a tricyclic antidepressant with selective noradrenergic effects, for developmental stuttering." | 9.08 | A double-blind comparison of clomipramine and desipramine in the treatment of developmental stuttering. ( Cotelingam, GM; Gordon, CT; Hamburger, SD; Ludlow, CL; Rapoport, JL; Stager, S, 1995) |
| "This study compared fluency changes in adult developmental stuttering speakers treated with two tricyclic antidepressants, clomipramine and desipramine." | 5.08 | Fluency changes in persons who stutter following a double blind trial of clomipramine and desipramine. ( Cotelingam, M; Gordon, CT; Ludlow, CL; Rapoport, JL; Stager, SV, 1995) |
| "Clomipramine, a serotonin reuptake blocker that has been shown to be effective in treating obsessive-compulsive disorder and other unwanted repetitive, ritualized behaviors, was hypothesized to be superior to desipramine, a tricyclic antidepressant with selective noradrenergic effects, for developmental stuttering." | 5.08 | A double-blind comparison of clomipramine and desipramine in the treatment of developmental stuttering. ( Cotelingam, GM; Gordon, CT; Hamburger, SD; Ludlow, CL; Rapoport, JL; Stager, S, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Stager, SV | 1 |
| Ludlow, CL | 2 |
| Gordon, CT | 2 |
| Cotelingam, M | 1 |
| Rapoport, JL | 2 |
| Cotelingam, GM | 1 |
| Stager, S | 1 |
| Hamburger, SD | 1 |
| Masand, P | 1 |
2 trials available for desipramine and Stuttering
| Article | Year |
|---|---|
Fluency changes in persons who stutter following a double blind trial of clomipramine and desipramine.
Topics: Adolescent; Adult; Clomipramine; Cross-Over Studies; Desipramine; Double-Blind Method; Female; Human | 1995 |
A double-blind comparison of clomipramine and desipramine in the treatment of developmental stuttering.
Topics: Adolescent; Adult; Attitude to Health; Clomipramine; Cross-Over Studies; Desipramine; Double-Blind M | 1995 |
1 other study available for desipramine and Stuttering
| Article | Year |
|---|---|
Desipramine-induced oral-pharyngeal disturbances: stuttering and jaw myoclonus.
Topics: Adult; Desipramine; Humans; Jaw; Male; Myoclonus; Stuttering | 1992 |