desipramine has been researched along with Pyrexia in 12 studies
Desipramine: A tricyclic dibenzazepine compound that potentiates neurotransmission. Desipramine selectively blocks reuptake of norepinephrine from the neural synapse, and also appears to impair serotonin transport. This compound also possesses minor anticholinergic activity, through its affinity to muscarinic receptors.
desipramine : A dibenzoazepine consisting of 10,11-dihydro-5H-dibenzo[b,f]azepine substituted on nitrogen with a 3-(methylamino)propyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Two schedules of imipramine (IM) administration were compared, a single intraperitoneal dose (10 mg/kg) (I) and chronic oral dosage (10 mg/kg twice a day for 14 days) (II)." | 1.26 | Different pharmacokinetic and pharmacological effects following acute and chronic treatment with imipramine. ( Daniel, W; Maj, J; Melzacka, M; Mogilnicka, E, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (83.33) | 18.7374 |
| 1990's | 1 (8.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (8.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sartori, SB | 1 |
| Whittle, N | 1 |
| Hetzenauer, A | 1 |
| Singewald, N | 1 |
| BOWEN, LW | 1 |
| Maj, J | 1 |
| Melzacka, M | 1 |
| Mogilnicka, E | 1 |
| Daniel, W | 1 |
| Gerber, SH | 1 |
| Heyer, C | 1 |
| Krüger, C | 1 |
| Hagl, S | 1 |
| Kübler, W | 1 |
| Haass, M | 1 |
| Benzi, RH | 1 |
| Shibata, M | 1 |
| Seydoux, J | 1 |
| Girardier, L | 1 |
| Loew, D | 1 |
| Taeschler, M | 1 |
| Jori, A | 3 |
| Carrara, C | 1 |
| Paglialunga, S | 2 |
| Garattini, S | 3 |
| Carrara, MC | 1 |
| Cranston, WI | 1 |
| Luff, RH | 1 |
| Schuckit, M | 1 |
| Robins, E | 1 |
| Feighner, J | 1 |
| Menon, MK | 1 |
| Dandiya, PC | 1 |
| Bapna, JS | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of One Month of Daily Consumption of Mineral Water Rich in Magnesium on Perceived Stress in Healthy Consumers.[NCT02719925] | 256 participants (Actual) | Interventional | 2016-07-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
12 other studies available for desipramine and Pyrexia
| Article | Year |
|---|---|
Magnesium deficiency induces anxiety and HPA axis dysregulation: modulation by therapeutic drug treatment.
Topics: Adrenocorticotropic Hormone; Analysis of Variance; Animals; Anxiety; Corticosterone; Corticotropin-R | 2012 |
FATAL HYPERPYREXIA WITH ANTIDEPRESSANT DRUGS.
Topics: Antidepressive Agents; Chlorpromazine; Desipramine; Fever; Mortality; Phenelzine; Toxicology | 1964 |
Different pharmacokinetic and pharmacological effects following acute and chronic treatment with imipramine.
Topics: Animals; Brain Chemistry; Desipramine; Fenfluramine; Fever; Imipramine; Male; Norepinephrine; Rats; | 1982 |
Influence of Bretschneider's cardioplegia on norepinephrine release from isolated perfused guinea-pig hearts.
Topics: Adrenergic Uptake Inhibitors; Amiloride; Animals; Desipramine; Dose-Response Relationship, Drug; Fev | 1999 |
Prepontine knife cut-induced hyperthermia in the rat. Effect of chemical sympathectomy and surgical denervation of brown adipose tissue.
Topics: Adipose Tissue, Brown; Animals; Body Temperature; Body Temperature Regulation; Colon; Denervation; D | 1988 |
[The effect of tricyclic antidepressants on rabbit 5-hydroxytryptophan hyperthermia].
Topics: Animals; Antidepressive Agents; Desipramine; Fever; Imipramine; Nortriptyline; Rabbits; Serotonin; T | 1966 |
Pharmacological studies on modaline sulphate (w 3207).
Topics: Antidepressive Agents; Desipramine; Dibenzylchlorethamine; Dihydroxyphenylalanine; Fever; Hydrazines | 1965 |
Importance of noradrenaline synthesis for the interaction between desipramine and reserpine.
Topics: Animals; Carbamates; Desipramine; Dihydroxyphenylalanine; Female; Fever; Norepinephrine; Rats; Reser | 1966 |
Effect of antidepressant and adrenergic blocking drugs on hyperthermia induced by reserpine.
Topics: Amitriptyline; Animals; Antidepressive Agents; Atropine; Body Temperature; Chlorisondamine; Chlorpro | 1967 |
The role of noradrenaline in the rabbit brain during pyrogen-induced fever.
Topics: Animals; Brain; Desipramine; Fever; Norepinephrine; Pyrogens; Rabbits | 1972 |
Tricyclic antidepressants and monoamine oxidase inhibitors.
Topics: Administration, Oral; Adolescent; Adult; Aged; Amitriptyline; Animals; Depression; Desipramine; Drug | 1971 |
Modification of the effect of some central stimulants in mice pretreated with alpha-methyl-1-tyrosine.
Topics: Animals; Body Temperature; Brain; Central Nervous System; Cocaine; Desipramine; Dextroamphetamine; E | 1967 |