desipramine has been researched along with Ptosis, Eyelid in 19 studies
Desipramine: A tricyclic dibenzazepine compound that potentiates neurotransmission. Desipramine selectively blocks reuptake of norepinephrine from the neural synapse, and also appears to impair serotonin transport. This compound also possesses minor anticholinergic activity, through its affinity to muscarinic receptors.
desipramine : A dibenzoazepine consisting of 10,11-dihydro-5H-dibenzo[b,f]azepine substituted on nitrogen with a 3-(methylamino)propyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Proadifen antagonized the action of IMI when investigated in reserpine hypothermia and ptosis and in the behavioral despair test." | 3.66 | Influence of proadifen, an inhibitor of the metabolism of drugs, on the action of imipramine and desipramine in rats. ( Daniel, W; Maj, J; Rogóz, Z; Skuza, G; Sowińska, H, 1981) |
| "Tramadol is a centrally acting analgesic that demonstrates opioid and monoaminergic properties." | 1.32 | Antidepressant-like effect of tramadol and its enantiomers in reserpinized mice: comparative study with desipramine, fluvoxamine, venlafaxine and opiates. ( Berrocoso, E; Gibert-Rahola, J; Micó, JA; Rojas-Corrales, MO, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (84.21) | 18.7374 |
| 1990's | 2 (10.53) | 18.2507 |
| 2000's | 1 (5.26) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Klioze, SS | 1 |
| Bauer, VJ | 1 |
| Geyer, HM | 3 |
| Maryanoff, BE | 1 |
| McComsey, DF | 1 |
| Gardocki, JF | 1 |
| Shank, RP | 1 |
| Costanzo, MJ | 1 |
| Nortey, SO | 1 |
| Schneider, CR | 1 |
| Setler, PE | 1 |
| Balsamo, A | 1 |
| Giorgi, I | 1 |
| Lapucci, A | 1 |
| Lucacchini, A | 1 |
| Macchia, B | 1 |
| Macchia, F | 1 |
| Martini, C | 1 |
| Rossi, A | 1 |
| Bonnaud, B | 1 |
| Cousse, H | 1 |
| Mouzin, G | 1 |
| Briley, M | 1 |
| Stenger, A | 1 |
| Fauran, F | 1 |
| Couzinier, JP | 1 |
| Saari, WS | 1 |
| Halczenko, W | 1 |
| Huff, JR | 1 |
| Guare, JP | 1 |
| Hunt, CA | 1 |
| Randall, WC | 1 |
| Lotti, VJ | 1 |
| Yarbrough, GG | 1 |
| Ong, HH | 2 |
| Profitt, JA | 2 |
| Fortunato, J | 1 |
| Glamkowski, EJ | 1 |
| Ellis, DB | 1 |
| Wilker, JC | 2 |
| Burghard, H | 1 |
| Kunstmann, R | 1 |
| Lerch, U | 1 |
| Gerhards, H | 1 |
| Leven, M | 1 |
| Schacht, U | 1 |
| Anderson, VB | 1 |
| Kruse, H | 1 |
| Rojas-Corrales, MO | 1 |
| Berrocoso, E | 1 |
| Gibert-Rahola, J | 1 |
| Micó, JA | 1 |
| Pendleton, RG | 2 |
| McCafferty, JP | 1 |
| Roesler, JM | 1 |
| Hieble, JP | 1 |
| Maj, J | 1 |
| Daniel, W | 1 |
| Rogóz, Z | 1 |
| Skuza, G | 1 |
| Sowińska, H | 1 |
| Miller, DA | 1 |
| Ridley, PT | 1 |
| Woods-Kettelberger, AT | 1 |
| Smith, CP | 1 |
| Corbett, R | 1 |
| Szewczak, MR | 1 |
| Roehr, JE | 1 |
| Bores, GM | 1 |
| Klein, JT | 1 |
| Kongsamut, S | 1 |
| Perrone, MH | 1 |
| Luttinger, D | 1 |
| Hamel, LT | 1 |
| Fritz, PM | 1 |
| Ferraino, R | 1 |
| Haubrich, DR | 1 |
| Cotillo, P | 1 |
| Bonaccorsi, A | 1 |
| Monkovic, I | 1 |
| Perron, YG | 1 |
| Martel, R | 1 |
| Simpson, WJ | 1 |
| Lapin, IP | 1 |
| Osipova, SV | 1 |
| Uskova, NV | 1 |
| Stabrovski, EM | 1 |
| Rohte, O | 1 |
| Avni, J | 1 |
| Edelstein, EL | 1 |
| Khazan, N | 1 |
| Sulman, FG | 1 |
19 other studies available for desipramine and Ptosis, Eyelid
| Article | Year |
|---|---|
Synthesis of spiro[isobenzofuran-1(3H),4'-piperidines] as potential central nervous system agents. 2. Compounds containing a heteroatom attached to nitrogen.
Topics: Animals; Antidepressive Agents; Benzofurans; Blepharoptosis; Methods; Mice; Piperidines; Structure-A | 1977 |
Pyrroloisoquinoline antidepressants. 2. In-depth exploration of structure-activity relationships.
Topics: Animals; Antidepressive Agents; Blepharoptosis; Brain; Catecholamines; Chemical Phenomena; Chemistry | 1987 |
3-[(2-ethoxyphenoxy)methyl]piperidine derivatives. Synthesis and antidepressant activity.
Topics: Animals; Antidepressive Agents; Blepharoptosis; Brain; Desipramine; Dopamine; Drug Evaluation, Precl | 1987 |
1-Aryl-2-(aminomethyl)cyclopropanecarboxylic acid derivatives. A new series of potential antidepressants.
Topics: Amino Acids; Animals; Antidepressive Agents; Behavior, Animal; Blepharoptosis; Cyclopropanes; Indica | 1987 |
Adrenoceptor and tetrabenazine antagonism activities of some pyridinyltetrahydropyridines.
Topics: Animals; Blepharoptosis; Cerebral Cortex; Clonidine; Male; Methoxamine; Mice; Pyridines; Rats; Recep | 1984 |
Novel tetracyclic spiropiperidines. 3. 1-arylspiro[indoline-3,4'-piperidine]s as potential antidepressants.
Topics: 5-Hydroxytryptophan; Animals; Antidepressive Agents; Biological Assay; Blepharoptosis; Drug Synergis | 1983 |
2,3,4,4a,5,9b-Hexahydro-1H-indeno[1,2-b]pyridines: potential antidepressants.
Topics: Animals; Antidepressive Agents; Biogenic Amines; Biological Transport; Blepharoptosis; Brain; Indene | 1984 |
Novel tetracyclic spiropiperidines. 1. 3-Aryl-1,3-dihydrospiro[benzo[c]thiophene-1,4'-piperidines] as potential antidepressants.
Topics: 5-Hydroxytryptophan; Animals; Antidepressive Agents, Tricyclic; Blepharoptosis; Chemical Phenomena; | 1981 |
Antidepressant-like effect of tramadol and its enantiomers in reserpinized mice: comparative study with desipramine, fluvoxamine, venlafaxine and opiates.
Topics: Analgesics, Opioid; Animals; Antidepressive Agents; Blepharoptosis; Body Temperature; Cyclohexanols; | 2004 |
Mechanism for gastric antisecretory effects of desmethylimipramine in rats.
Topics: Animals; Blepharoptosis; Desipramine; Drug Interactions; Gastric Mucosa; Guinea Pigs; In Vitro Techn | 1981 |
Influence of proadifen, an inhibitor of the metabolism of drugs, on the action of imipramine and desipramine in rats.
Topics: Animals; Blepharoptosis; Desipramine; Hypothermia; Imipramine; Male; Motor Activity; Proadifen; Rats | 1981 |
Studies on the putative anticholinergic effects of desmethylimipramine.
Topics: Animals; Atropine; Blepharoptosis; Carbachol; Defecation; Desipramine; Gastric Juice; Male; Mice; My | 1980 |
Besipirdine (HP 749) reduces schedule-induced polydipsia in rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Biogenic Amines; Blepharoptosis; Conditioning, Oper | 1996 |
In vivo assessment of napamezole, an alpha-2 adrenoceptor antagonist and monoamine re-uptake inhibitor.
Topics: Adrenergic alpha-Antagonists; Animals; Blepharoptosis; Brain; Clonidine; Conditioning, Operant; Desi | 1990 |
Observations on the interactions between desipramine and reserpine on adrenergic transmission in the rat.
Topics: Animals; Blepharoptosis; Desipramine; Electric Stimulation; Eyelids; Rats; Reserpine; Sympathetic Ne | 1972 |
Substituted tetrahydrofurfurylamines as potential antidepressants.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Blepharoptosis; Central Nervous System; Desipramin | 1973 |
Pharmacological effects of imipramine and desmethylimipramine in developing rats.
Topics: Age Factors; Animals; Animals, Newborn; Blepharoptosis; Brain Chemistry; Chlorpromazine; Desipramine | 1969 |
Observation of the grooming behaviour of reserpinized white mice as a method for investigating reserpine antagonism and synergism.
Topics: Administration, Oral; Animals; Antidepressive Agents; Blepharoptosis; Charcoal; Desipramine; Dextroa | 1970 |
Comparative study of imipramine, amitriptyline and their desmethyl analogues in the hypothyroid rat.
Topics: Amitriptyline; Animals; Blepharoptosis; Desipramine; Exploratory Behavior; Female; Hypothyroidism; I | 1967 |