Compounds > desipramine
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desipramine and Psychotic Disorders

desipramine has been researched along with Psychotic Disorders in 29 studies

Desipramine: A tricyclic dibenzazepine compound that potentiates neurotransmission. Desipramine selectively blocks reuptake of norepinephrine from the neural synapse, and also appears to impair serotonin transport. This compound also possesses minor anticholinergic activity, through its affinity to muscarinic receptors.
desipramine : A dibenzoazepine consisting of 10,11-dihydro-5H-dibenzo[b,f]azepine substituted on nitrogen with a 3-(methylamino)propyl group.

Psychotic Disorders: Disorders in which there is a loss of ego boundaries or a gross impairment in reality testing with delusions or prominent hallucinations. (From DSM-IV, 1994)

Research Excerpts

ExcerptRelevanceReference
"Desipramine was given at a dose of 50-100 mg/day for 3-5 weeks."1.26Abnormal anterior pituitary responsiveness to hypothalamic hormones in primary affective disorders. Effect of desipramine therapy. ( Brambilla, F; Massironi, R; Nobile, P; Pugnetti, L; Scarone, S, 1982)

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-199025 (86.21)18.7374
1990's4 (13.79)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
KRAKOWSKI, AJ2
OLESEN, KM1
HAASE, HJ1
KOESTER, H1
KOENIG, M1
BLEKER, A1
CMYRAL, K1
HOFMANN, G1
ALNAES, R2
KRISTIANSEN, J2
SEGERS, J1
NUYTS, JA1
PALESTINE, ML1
LAPOLLA, A1
Bohard, F1
Le Borgne, Y1
Guennoc, A1
Klein, H1
Masanes, P1
Genazzani, AR1
Petraglia, F1
Facchinetti, F1
Monittola, C1
Scarone, S2
Brambilla, F2
Nelson, JC2
Jatlow, PI1
Pi, EH1
Simpson, GM1
Massironi, R1
Nobile, P1
Pugnetti, L1
Price, LH1
Waltrip, RW1
Sabatino, M1
Cannizzaro, C1
Flugy, A1
Gagliand, M1
Mineo, A1
Cannizzaro, G1
Sichel, DA1
Cohen, LS1
Dimmock, JA1
Rosenbaum, JF1
Amore, M1
Giordani, L1
Giorgetti, G1
Zazzeri, N1
Davidson, JR1
McLeod, MN1
Kurland, AA1
White, HL1
Dinan, TG1
Barry, S1
Sharma, R1
Javaid, JI1
Janicak, P1
Faull, K1
Comaty, J1
Davis, JM1
Czartorysky, B1
Harding, J1
Siris, SG1
Adan, F1
Lee, A1
Cooper, TB1
Mandeli, J1
Casey, E1
Kriechman, AM1
Rodová, A1
Svestka, J1
Náhunek, K1
Vescovini, L1
Morselli, PL1
Rizzo, M1
Zaccala, M1
Garattini, S1

Reviews

1 review available for desipramine and Psychotic Disorders

ArticleYear
[Pharmacological treatment of delusional depression].
    Minerva psichiatrica, 1996, Volume: 37, Issue:1

    Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Delusions; Depressive Disorde

1996

Trials

3 trials available for desipramine and Psychotic Disorders

ArticleYear
Antidepressant drug therapy in psychotic depression.
    The British journal of psychiatry : the journal of mental science, 1977, Volume: 131

    Topics: Adult; Affective Disorders, Psychotic; Clinical Trials as Topic; Delusions; Desipramine; Double-Blin

1977
[Clinical experience with desipramine in endogenous and involutional depressions].
    Activitas nervosa superior, 1970, Jan-12, Volume: 12, Issue:1

    Topics: Adult; Aged; Bipolar Disorder; Clinical Trials as Topic; Depression; Depressive Disorder, Major; Des

1970
[Clinical research on a new antidepressive drug (desipramine) and its comparison with imipramine].
    Rivista sperimentale di freniatria e medicina legale delle alienazioni mentali, 1969, Aug-31, Volume: 93, Issue:4

    Topics: Adult; Aged; Clinical Trials as Topic; Desipramine; Female; Humans; Imipramine; Middle Aged; Psychop

1969

Other Studies

25 other studies available for desipramine and Psychotic Disorders

ArticleYear
TREATMENT OF SEVERE DEPRESSION WITH DESIPRAMINE, A METABOLITE OF IMIPRAMINE.
    The American journal of psychiatry, 1963, Volume: 120

    Topics: Adolescent; Antidepressive Agents; Brain Diseases; Depression; Depressive Disorder; Depressive Disor

1963
[ENDOGENOUS DEPRESSIONS TREATED WITH PERTOFRANE].
    Nordisk psykiatrisk tidsskrift. Nordic journal of psychiatry, 1963, Volume: 17

    Topics: Antidepressive Agents; Bipolar Disorder; Depressive Disorder; Desipramine; Humans; Psychotic Disorde

1963
[ON THE METHODOLOGY OF RESEARCH ON ANTIDEPRESSIVE DRUGS WITH SPECIAL REFERENCE TO IMIPRAMINE (TOFRANIL) AND DESMETHYLIMIPRAMINE (PERTOFRAN)].
    Archiv fur Psychiatrie und Nervenkrankheiten, 1963, Sep-18, Volume: 204

    Topics: Aging; Antidepressive Agents; Bipolar Disorder; Body Constitution; Desipramine; Humans; Imipramine;

1963
[RESULTS OF THE USE OF DESMETHYL-IMIPRAMINE (G-35020, PERTOFRAN) IN THE DEPRESSIVE SYNDROME].
    Wiener medizinische Wochenschrift (1946), 1963, Dec-07, Volume: 113

    Topics: Antidepressive Agents; Bipolar Disorder; Depressive Disorder; Desipramine; Humans; Imipramine; Menta

1963
[DESMETHYLIMIPRAMINE (PERTOFRAN) IN THE TREATMENT OF DEPRESSIONS. A CLINICAL AND PSYCHODYNAMIC APPRAISAL].
    Nordisk psykiatrisk tidsskrift. Nordic journal of psychiatry, 1963, Volume: 17

    Topics: Antidepressive Agents; Biomedical Research; Bipolar Disorder; Chlorpromazine; Depression; Depressive

1963
[DESIPRAMINE (PERTOFRAN) IN THE TREATMENT OF DEPRESSIONS WITH A PSYCHODYNAMIC ANALYSIS OF ITS THERAPEUTIC EFFECTS].
    Archiv fur Psychiatrie und Nervenkrankheiten, 1964, Mar-16, Volume: 205

    Topics: Antidepressive Agents; Biomedical Research; Bipolar Disorder; Depression; Depressive Disorder; Desip

1964
[ACTION OF DESMETHYL-IMIPRAMINE (PERTOFRAN) IN DEPRESSIVE SYNDROMES].
    Acta neurologica et psychiatrica Belgica, 1964, Volume: 64

    Topics: Antidepressive Agents; Bipolar Disorder; Depressive Disorder; Desipramine; Humans; Imipramine; Neuro

1964
TREATMENT OF SEVERE DEPRESSION WITH DESIPRAMINE: LONG-TERM TRIAL AND FOLLOW-UP.
    Diseases of the nervous system, 1964, Volume: 25

    Topics: Constipation; Depression; Depressive Disorder; Depressive Disorder, Major; Desipramine; Drug Hyperse

1964
DESIPRAMINE IN THE TREATMENT OF LONG STANDING PSYCHOTIC DISORDERS.
    Diseases of the nervous system, 1965, Volume: 26

    Topics: Depression; Desipramine; Drug Therapy; Hypnotics and Sedatives; Phenothiazines; Psychotic Disorders;

1965
CLINICAL TRIAL OF A NEW ANTIDEPRESSANT (DESIPRAMINE HYDROCHLORIDE) IN A HOSPITAL SETTING.
    The American journal of psychiatry, 1965, Volume: 121

    Topics: Antidepressive Agents; Biomedical Research; Bipolar Disorder; Depression; Depressive Disorder; Desip

1965
[Therapeutic trials with pertofran (G. 35-020) in depressive states].
    Annales medico-psychologiques, 1967, Volume: 125, Issue:3

    Topics: Depression; Desipramine; Humans; Psychotic Disorders

1967
Opioid plasma levels in primary affective disorders. Effect of desimipramine therapy.
    Neuropsychobiology, 1984, Volume: 12, Issue:2-3

    Topics: Adrenocorticotropic Hormone; Adult; Affective Disorders, Psychotic; Aged; beta-Endorphin; beta-Lipot

1984
Neuroloeptic effect on desipramine steady-state plasma concentratins.
    The American journal of psychiatry, 1980, Volume: 137, Issue:10

    Topics: Adult; Affective Disorders, Psychotic; Antipsychotic Agents; Desipramine; Drug Therapy, Combination;

1980
A trial of tricyclic antidepressant in RDC schizoaffective disorder, depressed type.
    The Hillside journal of clinical psychiatry, 1983, Volume: 5, Issue:1

    Topics: Adult; Depressive Disorder; Desipramine; Dose-Response Relationship, Drug; Female; Humans; Male; Psy

1983
Abnormal anterior pituitary responsiveness to hypothalamic hormones in primary affective disorders. Effect of desipramine therapy.
    Neuropsychobiology, 1982, Volume: 8, Issue:5

    Topics: Adult; Affective Disorders, Psychotic; Aged; Bipolar Disorder; Depressive Disorder; Desipramine; Fem

1982
Desipramine-associated hepatitis.
    Journal of clinical psychopharmacology, 1983, Volume: 3, Issue:4

    Topics: Adult; Chemical and Drug Induced Liver Injury; Depressive Disorder; Desipramine; Female; Humans; Liv

1983
Clinical conferences: Management of depression in older people.
    Journal of the American Geriatrics Society, 1982, Volume: 30, Issue:3

    Topics: Aged; Antidepressive Agents; Dementia; Depressive Disorder; Desipramine; Diagnosis, Differential; Do

1982
NMDA-GABA interactions in an animal model of behaviour: a gating mechanism from motivation toward psychotic-like symptoms.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 1994, Volume: 4, Issue:2

    Topics: Alprazolam; Animals; Behavior, Animal; Desipramine; Disease Models, Animal; Dizocilpine Maleate; gam

1994
Postpartum obsessive compulsive disorder: a case series.
    The Journal of clinical psychiatry, 1993, Volume: 54, Issue:4

    Topics: Adult; Clomipramine; Desipramine; Diagnosis, Differential; Female; Fluoxetine; Follow-Up Studies; Hu

1993
Responses of growth hormone to desipramine in endogenous and non-endogenous depression.
    The British journal of psychiatry : the journal of mental science, 1990, Volume: 156

    Topics: Adult; Aged; Bipolar Disorder; Depressive Disorder; Desipramine; Dexamethasone; Diagnosis, Different

1990
Plasma and CSF HVA before and after pharmacological treatment.
    Psychiatry research, 1989, Volume: 28, Issue:1

    Topics: Adult; Brain; Desipramine; Female; Homovanillic Acid; Humans; Lithium; Male; Psychiatric Status Rati

1989
QRS interval in tricyclic antidepressant overdose.
    The Journal of clinical psychiatry, 1988, Volume: 49, Issue:11

    Topics: Adult; Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Desipramine; Electrocardiography; Hea

1988
Patterns of plasma imipramine-desipramine concentrations in patients receiving concomitant fluphenazine decanoate.
    The Journal of clinical psychiatry, 1988, Volume: 49, Issue:2

    Topics: Adult; Depressive Disorder; Desipramine; Dose-Response Relationship, Drug; Drug Interactions; Drug T

1988
Desipramine and imipramine overdose in a psychotic adolescent.
    Journal of the American Academy of Child and Adolescent Psychiatry, 1987, Volume: 26, Issue:1

    Topics: Adolescent; Desipramine; Humans; Imipramine; Male; Psychotic Disorders; Suicide, Attempted

1987
Haloperidol-desipramine interaction in mice, rats and man.
    Chemico-biological interactions, 1970, Volume: 2, Issue:2

    Topics: Animals; Basal Ganglia Diseases; Benperidol; Butyrophenones; Chronic Disease; Desipramine; Drug Anta

1970