desipramine has been researched along with Premenstrual Tension in 7 studies
Desipramine: A tricyclic dibenzazepine compound that potentiates neurotransmission. Desipramine selectively blocks reuptake of norepinephrine from the neural synapse, and also appears to impair serotonin transport. This compound also possesses minor anticholinergic activity, through its affinity to muscarinic receptors.
desipramine : A dibenzoazepine consisting of 10,11-dihydro-5H-dibenzo[b,f]azepine substituted on nitrogen with a 3-(methylamino)propyl group.
Premenstrual Tension: A term used to describe the psychological aspects of PREMENSTRUAL SYNDROME, such as the indescribable tension, depression, hostility, and increased seizure activity in women with seizure disorder.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of this study was to compare the effect of the selective noradrenergic reuptake inhibitor desipramine and methylscopolamine bromide, a parasympatholytic agent, on late luteal phase dysphoric disorder (LLPDD), or premenstrual syndrome (PMS), as defined in DSM-III-R." | 9.08 | Premenstrual syndrome: a double-blind controlled trial of desipramine and methylscopolamine. ( Howard, RC; Mason, PA; Menkes, DB; Shaw, JP; Spears, GF; Taghavi, E, 1995) |
| "Posttreatment allopregnanolone levels were significantly lower in the improved compared with the unimproved subjects." | 6.70 | Allopregnanolone levels and symptom improvement in severe premenstrual syndrome. ( Freeman, EW; Frye, CA; Martin, PA; Rickels, K; Smith, SS, 2002) |
| "Sertraline was better tolerated, resulting in greater patient acceptance." | 6.68 | Sertraline versus desipramine in the treatment of premenstrual syndrome: an open-label trial. ( Freeman, EW; Rickels, K; Sondheimer, SJ; Wittmaack, FM, 1996) |
| "Nefazodone is a new antidepressant exhibiting properties of selective serotonin reuptake inhibition and serotonin-2 receptor antagonism." | 5.29 | Probable nefazodone-induced mania in a patient with unreported bipolar disorder. ( Blaisdell, GD; Jermain, DM; Zaphiris, HA, 1996) |
| "The aim of this study was to compare the effect of the selective noradrenergic reuptake inhibitor desipramine and methylscopolamine bromide, a parasympatholytic agent, on late luteal phase dysphoric disorder (LLPDD), or premenstrual syndrome (PMS), as defined in DSM-III-R." | 5.08 | Premenstrual syndrome: a double-blind controlled trial of desipramine and methylscopolamine. ( Howard, RC; Mason, PA; Menkes, DB; Shaw, JP; Spears, GF; Taghavi, E, 1995) |
| "Posttreatment allopregnanolone levels were significantly lower in the improved compared with the unimproved subjects." | 2.70 | Allopregnanolone levels and symptom improvement in severe premenstrual syndrome. ( Freeman, EW; Frye, CA; Martin, PA; Rickels, K; Smith, SS, 2002) |
| "Sertraline was significantly more effective than placebo or desipramine; desipramine was not better than placebo (F2,163 = 12." | 2.69 | Differential response to antidepressants in women with premenstrual syndrome/premenstrual dysphoric disorder: a randomized controlled trial. ( Freeman, EW; Polansky, M; Rickels, K; Sondheimer, SJ, 1999) |
| "Sertraline was better tolerated, resulting in greater patient acceptance." | 2.68 | Sertraline versus desipramine in the treatment of premenstrual syndrome: an open-label trial. ( Freeman, EW; Rickels, K; Sondheimer, SJ; Wittmaack, FM, 1996) |
| "Nefazodone is a new antidepressant exhibiting properties of selective serotonin reuptake inhibition and serotonin-2 receptor antagonism." | 1.29 | Probable nefazodone-induced mania in a patient with unreported bipolar disorder. ( Blaisdell, GD; Jermain, DM; Zaphiris, HA, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (57.14) | 18.2507 |
| 2000's | 3 (42.86) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Freeman, EW | 4 |
| Frye, CA | 1 |
| Rickels, K | 4 |
| Martin, PA | 1 |
| Smith, SS | 1 |
| Schneider, T | 1 |
| Popik, P | 1 |
| Taghavi, E | 1 |
| Menkes, DB | 1 |
| Howard, RC | 1 |
| Mason, PA | 1 |
| Shaw, JP | 1 |
| Spears, GF | 1 |
| Sondheimer, SJ | 3 |
| Wittmaack, FM | 1 |
| Zaphiris, HA | 1 |
| Blaisdell, GD | 1 |
| Jermain, DM | 1 |
| Polansky, M | 2 |
5 trials available for desipramine and Premenstrual Tension
| Article | Year |
|---|---|
Allopregnanolone levels and symptom improvement in severe premenstrual syndrome.
Topics: Adult; Antidepressive Agents; Antidepressive Agents, Tricyclic; Desipramine; Double-Blind Method; Fe | 2002 |
Premenstrual syndrome: a double-blind controlled trial of desipramine and methylscopolamine.
Topics: Adolescent; Adult; Cross-Over Studies; Desipramine; Double-Blind Method; Female; Humans; Luteal Phas | 1995 |
Sertraline versus desipramine in the treatment of premenstrual syndrome: an open-label trial.
Topics: 1-Naphthylamine; Adolescent; Adult; Depressive Disorder; Desipramine; Double-Blind Method; Female; H | 1996 |
Differential response to antidepressants in women with premenstrual syndrome/premenstrual dysphoric disorder: a randomized controlled trial.
Topics: Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Comorbidity; Depressive | 1999 |
Concurrent use of oral contraceptives with antidepressants for premenstrual syndromes.
Topics: Adolescent; Adult; Antidepressive Agents; Contraceptives, Oral; Desipramine; Double-Blind Method; Dr | 2001 |
2 other studies available for desipramine and Premenstrual Tension
| Article | Year |
|---|---|
Attenuation of estrous cycle-dependent marble burying in female rats by acute treatment with progesterone and antidepressants.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Desipramine; Estrous Cycle; Female; Fluoxetine; Mo | 2007 |
Probable nefazodone-induced mania in a patient with unreported bipolar disorder.
Topics: Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Bipolar Disorder; Depres | 1996 |