Page last updated: 2024-10-25

desipramine and Pregnancy

desipramine has been researched along with Pregnancy in 65 studies

Desipramine: A tricyclic dibenzazepine compound that potentiates neurotransmission. Desipramine selectively blocks reuptake of norepinephrine from the neural synapse, and also appears to impair serotonin transport. This compound also possesses minor anticholinergic activity, through its affinity to muscarinic receptors.
desipramine : A dibenzoazepine consisting of 10,11-dihydro-5H-dibenzo[b,f]azepine substituted on nitrogen with a 3-(methylamino)propyl group.

Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.

Research Excerpts

ExcerptRelevanceReference
"EEG sleep recordings and two provocative neuroendocrinological tests (the DST and the GH stimulation test after desipramine) were investigated in two depressed pubertal monozygotic twin boys with Major Depressive Disorder and compared with results from one normal pubertal control boy and an adolescent girl suffering from major depression."3.67Electroencephalogram and neuroendocrine parameters in pubertal and adolescent depressed children. A case report study. ( Hoffmann, G; Kerkhofs, M; Linkowski, P; Mendlewicz, J, 1984)
" In addition, dose-response curves for the inhibitory LC activity of clonidine showed a shift to the right in deprived animals indicating a subsensitivity of alpha2-adrenergic autoreceptors."1.31Increased neuronal activity in locus coeruleus from adult rats undernourished at perinatal age: its reversal by desipramine. ( Cuadra, GR; Nasif, FJ; Orsingher, OA; Ramírez, OA, 2001)
" Input files require estimates of binding coefficients, first- and/or second-order metabolism constants, level of interaction between the two chemicals, and dosing information."1.30A computer model and program for xenobiotic disposition during pregnancy. ( Luecke, RH; Pearce, BA; Wosilait, WD; Young, JF, 1997)
" These data show that 6-OHDA is not equally toxic to all brain DA neurons in neonates, and that all hypothalamic DA neuronal groups resist the toxicity of 6-OHDA, despite their anatomical and functional differences."1.29Resistance of hypothalamic dopaminergic neurons to neonatal 6-hydroxydopamine toxicity. ( Ibata, Y; Okamura, H; Yokoyama, C, 1993)
" Neither the prolactin nor the ACTH response was augmented significantly in the animals exposed prenatally to either nicotine dosage regimen, although there was a strong trend for the augmentation to occur in the low-dose nicotine exposed animals."1.29Exposure to threshold doses of nicotine in utero: III. Augmentation of the prolactin and ACTH response to 8-OH DPAT by desipramine treatment is compromised in adult male offspring. ( Acosta, S; Au, D; Lutchmansingh, P; McCracken, JT; McGeoy, S; Poland, RE; Que, M, 1996)
"The optimal treatment for depressive disorders in pregnancy remains controversial."1.27Electroconvulsive therapy in pregnancy. ( Berger, NG; Repke, JT, 1984)
"When desipramine (5mM) was added in order to block neuronal uptake the corresponding figures were 4."1.27Reduced uptake of noradrenaline into storage vesicles from the pregnant uterus. ( Dahlin, I; Fried, G; Hammarström, M, 1985)

Research

Studies (65)

TimeframeStudies, this research(%)All Research%
pre-199031 (47.69)18.7374
1990's20 (30.77)18.2507
2000's8 (12.31)29.6817
2010's6 (9.23)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Spulber, S2
Conti, M2
Elberling, F1
Raciti, M2
Borroto-Escuela, DO1
Fuxe, K1
Ceccatelli, S2
Hernández, A1
Fernández-Guasti, A1
Szkilnik, R1
Brus, R1
Malinowska-Borowska, J1
Nowak, D1
Waliczek, M1
Kostrzewa, RM1
Nowak, P1
Chartoff, EH1
Papadopoulou, M1
MacDonald, ML1
Parsegian, A1
Potter, D1
Konradi, C1
Carlezon, WA1
Craft, RM1
Kostick, ML1
Rogers, JA1
White, CL1
Tsutsui, KT1
Annamalai, B1
Mannangatti, P1
Arapulisamy, O1
Ramamoorthy, S1
Jayanthi, LD1
Vázquez, DM1
Eskandari, R1
Phelka, A1
López, JF1
Will, CC1
Aird, F1
Redei, EE1
MacQueen, GM1
Ramakrishnan, K1
Ratnasingan, R1
Chen, B1
Young, LT1
Lenkey, N1
Karoly, R2
Kiss, JP2
Szasz, BK2
Vizi, ES2
Mike, A2
Gerevich, Z1
Illes, P1
Mendlewicz, J1
Hoffmann, G1
Kerkhofs, M1
Linkowski, P1
Beaulieu, M1
Coyle, JT1
Savchenko, ON1
Podsedlovski, RT1
Strel'tsova, NA1
Danilova, OA1
Stout, SA2
DeVane, CL2
Simpkins, JW1
Das, S1
Datta, SC1
Guin, AK1
Dey, S1
Sengupta, D1
Repke, JT1
Berger, NG1
Biegon, A1
Yavin, Z1
Yavin, E1
Samuel, D1
Poland, RE2
Lutchmansingh, P2
McGeoy, S2
Au, D2
Que, M2
Acosta, S2
Edelstein, M1
McCracken, JT2
Yuwiler, A1
Taylor, AN1
Mione, MC1
Cavanagh, JF1
Burnstock, G1
Cannizzaro, C2
Cannizzaro, E2
Gagliano, M2
Mineo, A1
Sabatino, M1
Cannizzaro, G1
Snyder, DL1
Gayheart, P1
Johnson, MD1
Gurdal, H1
Roberts, J1
Saraf, HA1
Dombrowski, MP1
Leach, KC1
Hurd, WW1
Yokoyama, C1
Okamura, H1
Ibata, Y1
al-Damluji, S1
Krsmanovic, LZ1
Catt, KJ1
Schottenfeld, RS1
Wainwright, PE1
Huang, YS1
Lévesque, S1
Mutsaers, L1
McCutcheon, D1
Balcaen, P1
Hammond, J1
Mangiapane, N1
Luecke, RH1
Wosilait, WD1
Pearce, BA1
Young, JF1
Mortensen, OV1
Kristensen, AS1
Rudnick, G1
Wiborg, O1
Molina-Hernández, M1
Téllez-Alcántara, NP1
Nasif, FJ1
Ramírez, OA1
Cuadra, GR2
Orsingher, OA4
Rastogi, RB1
Singhal, RL1
Hrdina, PD1
Jameson, D1
Buckle, P1
Breese, GR1
Vogel, RA1
Kuhn, CM1
Mailman, RB1
Mueller, RA1
Schanberg, SM1
Cramer, OM1
Barraclough, CA1
Levitt, P1
Moore, RY1
Bal, AK1
Bird, MM2
de la Lande, IS1
Marino, V1
Lavranos, T1
Kennedy, JA1
Parker, DA1
Seamark, RF1
Slotkin, TA1
Lappi, SE1
Tayyeb, MI1
Seidler, FJ1
Keller, EA3
Molina, VA3
Bal-Klara, A1
Balkovetz, DF1
Tiruppathi, C1
Leibach, FH1
Mahesh, VB1
Ganapathy, V1
Fried, G1
Hammarström, M1
Dahlin, I1
Spina, E1
Pacifici, GM1
von Bahr, C1
Rane, A2
Vessell, ES1
Passananti, GT1
Webster, PA1
Lanza, M1
Chichmanian, RM1
Goude, F1
Bell, C1
Vogt, M1
Ahlskog, JE1
Evans, DA1
Elchisak, MA1
Rosecrans, JA1
Lunde, PK1
Jalling, B1
Yaffe, SJ1
Sjöqvist, F1
Scanlon, FJ1
Aeppli, L1
Lindström, LH1
Dyer, DC1
Hume, AS1
Douglas, BH1

Reviews

2 reviews available for desipramine and Pregnancy

ArticleYear
Utility of clinical chemical determinations of drug concentrations in biological fluids.
    Clinical chemistry, 1971, Volume: 17, Issue:9

    Topics: Adult; Allopurinol; Antipyrine; Ataxia; Chemistry, Clinical; Chromatography, Gas; Coffee; Desipramin

1971
The ecology of drug therapy.
    Birth defects original article series, 1974, Volume: 10, Issue:10

    Topics: Adrenal Cortex Hormones; Biological Evolution; Desipramine; Ethnicity; Female; Genetic Variation; Ge

1974

Other Studies

63 other studies available for desipramine and Pregnancy

ArticleYear
Desipramine restores the alterations in circadian entrainment induced by prenatal exposure to glucocorticoids.
    Translational psychiatry, 2019, 10-17, Volume: 9, Issue:1

    Topics: Animals; Antidepressive Agents, Tricyclic; Circadian Rhythm; Depression; Desipramine; Dexamethasone;

2019
Depressive-like phenotype induced by prenatal dexamethasone in mice is reversed by desipramine.
    Neuropharmacology, 2017, Volume: 126

    Topics: Animals; Antidepressive Agents, Tricyclic; Dendrites; Depression; Desipramine; Dexamethasone; Female

2017
Male rats with same-sex preference show higher immobility in the forced swim test, but similar effects of fluoxetine and desipramine than males that prefer females.
    Pharmacology, biochemistry, and behavior, 2018, Volume: 171

    Topics: Animals; Desipramine; Female; Fluoxetine; Immobility Response, Tonic; Letrozole; Male; Motor Activit

2018
Ontogenetic manganese exposure with perinatal 6-OHDA lesioning alters behavioral responses of rats to dopamine D₁ and D2 agonist treatments.
    Environmental toxicology and pharmacology, 2014, Volume: 37, Issue:1

    Topics: Animals; Behavior, Animal; Desipramine; Dopamine; Dopamine Agonists; Exploratory Behavior; Female; H

2014
Desipramine reduces stress-activated dynorphin expression and CREB phosphorylation in NAc tissue.
    Molecular pharmacology, 2009, Volume: 75, Issue:3

    Topics: Animals; Cells, Cultured; Cyclic AMP Response Element-Binding Protein; Desipramine; Dynorphins; Fema

2009
Forced swim test behavior in postpartum rats.
    Pharmacology, biochemistry, and behavior, 2010, Volume: 96, Issue:4

    Topics: Animals; Antidepressive Agents; Behavior, Animal; Desipramine; Female; Neurotransmitter Uptake Inhib

2010
Involvement of threonine 258 and serine 259 motif in amphetamine-induced norepinephrine transporter endocytosis.
    Journal of neurochemistry, 2010, Volume: 115, Issue:1

    Topics: Adrenergic Uptake Inhibitors; Amphetamine; Biotinylation; Calcium; Calcium-Calmodulin-Dependent Prot

2010
Impact of maternal deprivation on brain corticotropin-releasing hormone circuits: prevention of CRH receptor-2 mRNA changes by desipramine treatment.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2003, Volume: 28, Issue:5

    Topics: Animals; Brain; Corticotropin-Releasing Hormone; Desipramine; Female; Male; Maternal Deprivation; Ne

2003
Selectively bred Wistar-Kyoto rats: an animal model of depression and hyper-responsiveness to antidepressants.
    Molecular psychiatry, 2003, Volume: 8, Issue:11

    Topics: Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Breeding; Depressive Disorder; Desipram

2003
Desipramine treatment reduces the long-term behavioural and neurochemical sequelae of early-life maternal separation.
    The international journal of neuropsychopharmacology, 2003, Volume: 6, Issue:4

    Topics: Animals; Animals, Newborn; Antidepressive Agents, Tricyclic; Brain-Derived Neurotrophic Factor; Dent

2003
The mechanism of activity-dependent sodium channel inhibition by the antidepressants fluoxetine and desipramine.
    Molecular pharmacology, 2006, Volume: 70, Issue:6

    Topics: Animals; Antidepressive Agents, Second-Generation; Desipramine; Dose-Response Relationship, Drug; Fe

2006
Direct inhibitory effect of fluoxetine on N-methyl-D-aspartate receptors in the central nervous system.
    Biological psychiatry, 2007, Dec-01, Volume: 62, Issue:11

    Topics: Algorithms; Animals; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Bin

2007
Electroencephalogram and neuroendocrine parameters in pubertal and adolescent depressed children. A case report study.
    Journal of affective disorders, 1984, Volume: 6, Issue:3-4

    Topics: Adolescent; Depressive Disorder; Desipramine; Dexamethasone; Diseases in Twins; Electroencephalograp

1984
Fetally-induced noradrenergic hyperinnervation of cerebral cortex results in persistent down-regulation of beta-receptors.
    Brain research, 1982, Volume: 256, Issue:4

    Topics: Animals; Azo Compounds; Cerebral Cortex; Desipramine; Dihydroalprenolol; Female; Hydroxydopamines; K

1982
[Effect of 6-hydroxydopamine and 5,6-Dihydroxytryptophan on the luliberin and luteinizing hormone levels in female rats under constant illumination].
    Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova, 1983, Volume: 69, Issue:9

    Topics: 5-Hydroxytryptophan; Animals; Desipramine; Estrus; Female; Gonadotropin-Releasing Hormone; Hydroxydo

1983
Quantification of imipramine and its major metabolites in whole blood, brain, and other tissues of the rat by liquid chromatography.
    Psychopharmacology, 1984, Volume: 84, Issue:1

    Topics: Animals; Brain; Chromatography, High Pressure Liquid; Desipramine; Female; Fetus; Imipramine; Pregna

1984
Cerebral and blood pharmacokinetics of imipramine and its active metabolites in the pregnant rat.
    Psychopharmacology, 1984, Volume: 84, Issue:2

    Topics: Animals; Brain; Desipramine; Erythrocytes; Female; Imipramine; Kinetics; Male; Pregnancy; Rats; Rats

1984
Role of imipramine & desipramine in counteracting diazepam induced changes of adenosinetriphosphatase & cholinesterase of human fetal brain.
    Indian journal of experimental biology, 1981, Volume: 19, Issue:8

    Topics: Adenosine Triphosphatases; Brain; Cholinesterases; Desipramine; Diazepam; Female; Fetus; Gestational

1981
Electroconvulsive therapy in pregnancy.
    Obstetrics and gynecology, 1984, Volume: 63, Issue:3 Suppl

    Topics: Depressive Disorder; Desipramine; Electroconvulsive Therapy; Female; Humans; Infant, Newborn; Pregna

1984
Characterization and ontogenesis of [3H]-desipramine binding sites in developing fetal rat cerebral cells in culture.
    Biochemical pharmacology, 1980, Jun-15, Volume: 29, Issue:12

    Topics: Animals; Binding Sites; Binding, Competitive; Brain; Cells, Cultured; Desipramine; Female; Fetus; Hy

1980
Prenatal stress prevents the desensitization of the corticosterone response to TFMPP by desmethylimipramine, but not by phenelzine, in adult male offspring.
    Life sciences, 1995, Volume: 57, Issue:23

    Topics: Adaptation, Physiological; Animals; Antidepressive Agents; Corticosterone; Desipramine; Female; Male

1995
Prenatal alcohol exposure and pineal response to isoproterenol, vasoactive intestinal polypeptide, and desmethylimipramine.
    Journal of pineal research, 1995, Volume: 18, Issue:2

    Topics: Animals; Animals, Newborn; Arylamine N-Acetyltransferase; Desipramine; Ethanol; Female; Isoprotereno

1995
Uptake of 5-hydroxydopamine into non-sympathetic nerves of guinea-pig uterine artery in late pregnancy.
    Journal of neurocytology, 1993, Volume: 22, Issue:3

    Topics: Animals; Arteries; Axons; Cocaine; Desipramine; Dopamine beta-Hydroxylase; Female; Guinea Pigs; Hydr

1993
Effects of desipramine and alprazolam on forced swimming behaviour of adult rats exposed to prenatal diazepam.
    European journal of pharmacology, 1995, Feb-06, Volume: 273, Issue:3

    Topics: Alprazolam; Animals; Behavior, Animal; Depression; Desipramine; Diazepam; Electroencephalography; El

1995
Prenatal cocaine exposure alters norepinephrine release from cardiac adrenergic nerve terminals.
    Life sciences, 1995, Volume: 56, Issue:18

    Topics: Adrenergic Fibers; Animals; Body Weight; Cocaine; Desipramine; Female; Heart; Ionomycin; Male; Myoca

1995
Characterization of the effect of cocaine on catecholamine uptake by pregnant myometrium.
    Obstetrics and gynecology, 1995, Volume: 85, Issue:1

    Topics: Analysis of Variance; Cocaine; Corticosterone; Desipramine; Ethylmaleimide; Female; Humans; In Vitro

1995
Resistance of hypothalamic dopaminergic neurons to neonatal 6-hydroxydopamine toxicity.
    Brain research bulletin, 1993, Volume: 30, Issue:5-6

    Topics: Animals; Animals, Newborn; Desipramine; Dopamine; Female; Hypothalamus; Immunohistochemistry; Inject

1993
High-affinity uptake of noradrenaline in postsynaptic neurones.
    British journal of pharmacology, 1993, Volume: 109, Issue:2

    Topics: Animals; Cell Membrane; Cells, Cultured; Desipramine; Female; Gonadotropin-Releasing Hormone; Hypoth

1993
Clinical trials of pharmacologic treatments in pregnant women--methodologic considerations.
    NIDA research monograph, 1995, Volume: 149

    Topics: Bromocriptine; Buprenorphine; Clinical Trials as Topic; Desipramine; Dopamine Agonists; Female; Huma

1995
Effects of dietary gamma-linolenic acid and prenatal ethanol on mouse brain and behavior.
    Pharmacology, biochemistry, and behavior, 1996, Volume: 53, Issue:4

    Topics: Adrenergic Uptake Inhibitors; Animals; Behavior, Animal; Brain Chemistry; Central Nervous System Dep

1996
Exposure to threshold doses of nicotine in utero: III. Augmentation of the prolactin and ACTH response to 8-OH DPAT by desipramine treatment is compromised in adult male offspring.
    Neurotoxicology, 1996,Summer, Volume: 17, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic Uptake Inhibitors; Adrenocorticotropic Hormone; A

1996
Behavioural responsiveness to picrotoxin and desipramine in adult rats prenatally exposed to different benzodiazepine receptor agonists.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 1995, Volume: 5, Issue:4

    Topics: Adrenergic Uptake Inhibitors; Alprazolam; Animals; Behavior, Animal; Desipramine; Diazepam; Female;

1995
A computer model and program for xenobiotic disposition during pregnancy.
    Computer methods and programs in biomedicine, 1997, Volume: 53, Issue:3

    Topics: Animals; Computer Simulation; Desipramine; Female; Humans; Imipramine; Maternal-Fetal Exchange; Merc

1997
Molecular cloning, expression and characterization of a bovine serotonin transporter.
    Brain research. Molecular brain research, 1999, Jul-23, Volume: 71, Issue:1

    Topics: Amino Acid Sequence; Animals; Carrier Proteins; Cattle; Citalopram; Cloning, Molecular; Desipramine;

1999
Antidepressant-like actions of pregnancy, and progesterone in Wistar rats forced to swim.
    Psychoneuroendocrinology, 2001, Volume: 26, Issue:5

    Topics: Animals; Antidepressive Agents; Behavior, Animal; Desipramine; Female; Motor Activity; Ovariectomy;

2001
Increased neuronal activity in locus coeruleus from adult rats undernourished at perinatal age: its reversal by desipramine.
    Life sciences, 2001, Oct-12, Volume: 69, Issue:21

    Topics: Animals; Clonidine; Desipramine; Female; Locus Coeruleus; Models, Animal; Neurons; Nutrition Disorde

2001
Influence of desmethylimipramine on some neurochemical alterations during experimental hypothyroidism.
    Neuropharmacology, 1975, Volume: 14, Issue:10

    Topics: Acetylcholine; Animals; Brain; Brain Chemistry; Desipramine; Dopamine; Female; Hypothyroidism; Methi

1975
A comparison of anti-inflammatory and other compounds on the spontaneously contracting pregnant rat uterus.
    The Journal of pharmacy and pharmacology, 1977, Volume: 29, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Chlorpromazine; Desipramine; Diazepam; Female; In Vitro Technique

1977
Behavioral and prolactin responses to 5-hydroxytryptophan in rats treated during development with 5,7-dihydroxytryptamine.
    Brain research, 1978, Oct-27, Volume: 155, Issue:2

    Topics: 5-Hydroxytryptophan; 5,7-Dihydroxytryptamine; Animals; Animals, Newborn; Behavior, Animal; Benserazi

1978
The actions of serotonin, norepinephrine, and epinephrine on hypothalamic processes leading to adenohypophyseal luteinizing hormone release.
    Endocrinology, 1978, Volume: 103, Issue:3

    Topics: Animals; Desipramine; Epinephrine; Female; Hypothalamus; Luteinizing Hormone; Norepinephrine; Pituit

1978
Development of the noradrenergic innervation of neocortex.
    Brain research, 1979, Feb-23, Volume: 162, Issue:2

    Topics: Adrenergic Fibers; Age Factors; Animals; Animals, Newborn; Axons; Brain Mapping; Cell Differentiatio

1979
Changes in the amount and distribution of neuronal alkaline and acid phosphatase after chronic exposure of cultures of cingulate cortex to antidepressant drugs.
    Journal of neural transmission. General section, 1992, Volume: 90, Issue:1

    Topics: Acid Phosphatase; Alkaline Phosphatase; Amitriptyline; Animals; Antidepressive Agents; Cells, Cultur

1992
Distribution of extraneuronal uptake1 in reproductive tissues: studies on cells in culture.
    Journal of neural transmission. Supplementum, 1991, Volume: 34

    Topics: Amnion; Animals; Biological Transport; Cell Line; Cells, Cultured; Cocaine; Desipramine; Female; Hum

1991
Dose-dependent glucocorticoid effects on noradrenergic synaptogenesis in rat brain: ontogeny of [3H]desmethylimipramine binding sites after fetal exposure to dexamethasone.
    Research communications in chemical pathology and pharmacology, 1991, Volume: 73, Issue:1

    Topics: Animals; Binding Sites; Brain; Desipramine; Dexamethasone; Female; Fetus; Glucocorticoids; Maternal-

1991
Lack of neuronal adaptive changes following chronic treatments in perinatally undernourished rats.
    Pharmacology, biochemistry, and behavior, 1990, Volume: 37, Issue:4

    Topics: Adaptation, Physiological; Animals; Apomorphine; Clonidine; Desipramine; Female; Motor Activity; Neu

1990
Perinatal undernutrition affects brain modulatory capacity of beta-adrenergic receptors in adult rats.
    The Journal of nutrition, 1990, Volume: 120, Issue:3

    Topics: Analysis of Variance; Animals; Brain; Caseins; Cerebral Cortex; Desipramine; Dihydroalprenolol; Fema

1990
The effects of various antidepressant drugs on the fine-structure of neurons of the cingulate cortex in culture.
    Neuroscience, 1990, Volume: 37, Issue:3

    Topics: Amitriptyline; Animals; Antidepressive Agents; Citalopram; Cytoskeleton; Desipramine; Female; Gyrus

1990
Evidence for an imipramine-sensitive serotonin transporter in human placental brush-border membranes.
    The Journal of biological chemistry, 1989, Feb-05, Volume: 264, Issue:4

    Topics: Carrier Proteins; Cations, Monovalent; Desipramine; Female; Humans; Hydralazine; Imipramine; Kinetic

1989
Reduced uptake of noradrenaline into storage vesicles from the pregnant uterus.
    Acta physiologica Scandinavica, 1985, Volume: 123, Issue:3

    Topics: Adenosine Triphosphate; Animals; Desipramine; Female; Guinea Pigs; Magnesium; Nerve Degeneration; No

1985
Reduced anti-immobility effect of repeated desipramine (DMI) treatment in adult rats undernourished at perinatal age.
    Pharmacology, biochemistry, and behavior, 1987, Volume: 26, Issue:2

    Topics: Animals; Depression; Desipramine; Disease Models, Animal; Drug Administration Schedule; Female; Male

1987
Characterization of desmethylimipramine 2-hydroxylation in human foetal and adult liver microsomes.
    Acta pharmacologica et toxicologica, 1986, Volume: 58, Issue:4

    Topics: Adult; Cytochrome P-450 Enzyme System; Desipramine; Female; Fetus; Humans; Hydroxylation; In Vitro T

1986
Withdrawal symptoms in neonates associated with maternal antidepressant therapy.
    Lancet (London, England), 1973, Aug-11, Volume: 2, Issue:7824

    Topics: Adult; Depression; Desipramine; Female; Fetus; Humans; Infant, Newborn; Infant, Newborn, Diseases; M

1973
[Action of various tricyclic antidepressive agents on the estrous cycle of the female rat].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1970, Volume: 164, Issue:6

    Topics: Amitriptyline; Animals; Antidepressive Agents; Desipramine; Dibenzazepines; Estrus; Female; Imiprami

1970
Release of endogenous noradrenaline from an isolated muscular artery. Release of endogenous noradrenaline from an isolated muscular artery.
    The Journal of physiology, 1971, Volume: 215, Issue:2

    Topics: Animals; Arteries; Axons; Cycloparaffins; Desipramine; Electric Stimulation; Female; Guinea Pigs; Ip

1971
Food intake and amphetamine anorexia after selective forebrain norepinephrine loss.
    Brain research, 1974, Dec-27, Volume: 82, Issue:2

    Topics: Amphetamine; Animals; Appetite; Body Weight; Brain Chemistry; Cerebral Cortex; Desipramine; Drinking

1974
Effect of central catecholamine depletions by 6-hydroxydopamine on morphine antinociception in rats.
    Research communications in chemical pathology and pharmacology, 1973, Volume: 6, Issue:1

    Topics: Animals; Behavior, Animal; Brain; Brain Stem; Catecholamines; Desipramine; Dopamine; Female; Hydroxy

1973
Plasma protein binding of diphenylhydantoin in normal and hyperbilirubinemic infants.
    The Journal of pediatrics, 1971, Volume: 78, Issue:5

    Topics: Bilirubin; Binding Sites; Blood Proteins; Carbon Isotopes; Desipramine; Female; Filtration; Humans;

1971
Use of antidepressant drugs during the first trimester.
    The Medical journal of Australia, 1969, Nov-22, Volume: 2, Issue:21

    Topics: Amitriptyline; Desipramine; Embryo, Mammalian; Female; Gestational Age; Humans; Imipramine; Nortript

1969
[Teratologic studies with imipramine in rats and rabbits. Planning and interpretation of teratologic studies under consideration of the biochemistry and toxicology of test substance].
    Arzneimittel-Forschung, 1969, Volume: 19, Issue:10

    Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Animals; Body Weight; Desipramine; Drug Toleranc

1969
The effect of pilocarpine in combination with monoamine oxidase inhibitors, imipramine or desmethylimipramine on oestrous behaviour in female rats.
    Psychopharmacologia, 1970, Volume: 17, Issue:2

    Topics: Amines; Animals; Body Temperature; Castration; Central Nervous System; Desipramine; Drug Synergism;

1970
An investigation of the mechanism of potentiation by cocaine of responses to serotonin in sheep umbilical blood vessels.
    The Journal of pharmacology and experimental therapeutics, 1970, Volume: 175, Issue:3

    Topics: Animals; Cocaine; Cyanides; Desipramine; Dinitrophenols; Drug Synergism; Female; In Vitro Techniques

1970
Placental transfer of desmethylimipramine.
    American journal of obstetrics and gynecology, 1968, Aug-01, Volume: 101, Issue:7

    Topics: Animals; Desipramine; Female; Fetus; Fluorometry; Imipramine; Injections, Intramuscular; Maternal-Fe

1968
A new antidepressant: desipramine hydrochloride (Norpramin, Pertofrane).
    JAMA, 1965, Oct-04, Volume: 194, Issue:1

    Topics: Adolescent; Aged; Animals; Child; Desipramine; Female; Humans; Imipramine; Pregnancy

1965