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desipramine and Poisoning

desipramine has been researched along with Poisoning in 10 studies

Desipramine: A tricyclic dibenzazepine compound that potentiates neurotransmission. Desipramine selectively blocks reuptake of norepinephrine from the neural synapse, and also appears to impair serotonin transport. This compound also possesses minor anticholinergic activity, through its affinity to muscarinic receptors.
desipramine : A dibenzoazepine consisting of 10,11-dihydro-5H-dibenzo[b,f]azepine substituted on nitrogen with a 3-(methylamino)propyl group.

Poisoning: Used with drugs, chemicals, and industrial materials for human or animal poisoning, acute or chronic, whether the poisoning is accidental, occupational, suicidal, by medication error, or by environmental exposure.

Research Excerpts

ExcerptRelevanceReference
"Nortriptyline was not detected in most cases, suggesting that it may degrade more rapidly than desipramine."1.29The study of tricyclic antidepressants in formalin-fixed human liver and formalin solutions. ( Wahba, WW; Winek, CL; Zaveri, NR, 1993)
" A dose-response relationship was evident; animals given the highest dose of desipramine-specific Fab showed the greatest improvement."1.29Ovine desipramine antibody fragments reverse desipramine cardiovascular toxicity in the rat. ( Dart, RC; Egen, NB; Garcia, RA; Sidki, A; Sullivan, JB, 1996)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19906 (60.00)18.7374
1990's4 (40.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Winek, CL1
Zaveri, NR1
Wahba, WW1
Woolf, PK1
Dart, RC1
Sidki, A1
Sullivan, JB1
Egen, NB1
Garcia, RA1
Bickel, MH1
Probst, BD1
Cetta, F1
Hursting, MJ1
Raisys, VA1
Opheim, KE1
Berry, DJ1
Grove, J1
Gard, H1
Knapp, D1
Hanenson, I1
Walle, T1
Gaffney, T1
Treitman, P1
Louis, C1
Olbing, H1
Bohlmann, HG1
Philippou, A1
Heimsoth, V1

Reviews

1 review available for desipramine and Poisoning

ArticleYear
Poisoning by tricyclic antidepressant drugs: general and pharmacokinetic considerations.
    International journal of clinical pharmacology and biopharmacy, 1975, Volume: 11, Issue:2

    Topics: Accidents, Home; Adolescent; Adult; Aged; Amitriptyline; Animals; Antidepressive Agents; Antidepress

1975

Other Studies

9 other studies available for desipramine and Poisoning

ArticleYear
The study of tricyclic antidepressants in formalin-fixed human liver and formalin solutions.
    Forensic science international, 1993, Volume: 61, Issue:2-3

    Topics: Amitriptyline; Cryopreservation; Desipramine; Drug Overdose; Drug Stability; Embalming; Evaluation S

1993
A 13 year old with desipramine ingestion.
    Pediatric emergency care, 1993, Volume: 9, Issue:4

    Topics: Adolescent; Bundle-Branch Block; Desipramine; Electrocardiography; Humans; Male; Poisoning; Tachycar

1993
Ovine desipramine antibody fragments reverse desipramine cardiovascular toxicity in the rat.
    Annals of emergency medicine, 1996, Volume: 27, Issue:3

    Topics: Animals; Antidepressive Agents, Tricyclic; Blood Pressure; Desipramine; Heart; Heart Conduction Syst

1996
The utility of a 12-lead electrocardiogram in diagnosing a suspected antidepressant overdose.
    Clinical pediatrics, 1992, Volume: 31, Issue:10

    Topics: Adolescent; Bicarbonates; Desipramine; Drug Overdose; Electrocardiography; Emergency Service, Hospit

1992
Drug-specific Fab therapy in drug overdose.
    Archives of pathology & laboratory medicine, 1987, Volume: 111, Issue:8

    Topics: Antidotes; Desipramine; Digoxin; Humans; Immunoglobulin Fab Fragments; Phencyclidine; Poisoning

1987
Emergency toxicological screening for drugs commonly taken in overdose.
    Journal of chromatography, 1973, Volume: 80, Issue:2

    Topics: Acetaminophen; Antidepressive Agents; Barbiturates; Benzazepines; Chloral Hydrate; Chromatography, T

1973
Studies on the disposition of amitriptyline and other tricyclic antidepressant drugs in man as it relates to the management of the overdosed patient.
    Advances in biochemical psychopharmacology, 1973, Volume: 7

    Topics: Adult; Amitriptyline; Antidepressive Agents; Charcoal; Chromatography, Gas; Desipramine; Female; Gas

1973
Desipramine poisoning.
    JAMA, 1972, May-08, Volume: 220, Issue:6

    Topics: Desipramine; Diazepam; Gastric Lavage; Humans; Infant; Lidocaine; Male; Paraldehyde; Poisoning; Pota

1972
[Therapy of imipramine poisoning in the child].
    Deutsche medizinische Wochenschrift (1946), 1970, Oct-09, Volume: 95, Issue:41

    Topics: Child; Chloral Hydrate; Desipramine; Diuresis; Exchange Transfusion, Whole Blood; Humans; Imipramine

1970