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desipramine and Pheochromocytoma, Extra-Adrenal

desipramine has been researched along with Pheochromocytoma, Extra-Adrenal in 14 studies

Desipramine: A tricyclic dibenzazepine compound that potentiates neurotransmission. Desipramine selectively blocks reuptake of norepinephrine from the neural synapse, and also appears to impair serotonin transport. This compound also possesses minor anticholinergic activity, through its affinity to muscarinic receptors.
desipramine : A dibenzoazepine consisting of 10,11-dihydro-5H-dibenzo[b,f]azepine substituted on nitrogen with a 3-(methylamino)propyl group.

Research Excerpts

ExcerptRelevanceReference
"PC12 pheochromocytoma cells take up 3,4-dihydroxyphenylethylamine (dopamine) and norepinephrine by a Na+-dependent, cocaine-sensitive system."7.67Characterization of xylamine binding to proteins of PC12 pheochromocytoma cells. ( Cho, AK; Howard, BD; Koide, M, 1986)
"The protein properties of the neuronal sodium-dependent noradrenaline (NA) transporter of PC12 (rat pheochromocytoma) cells and of bovine adreno-medullary cells were studied by means of binding of 3H-desipramine (3H-DMI)."3.68Biochemical characterization and purification of the neuronal sodium-dependent noradrenaline transporter. ( Blum, B; Bönisch, H; Martiny-Baron, G; Michael-Hepp, J, 1990)
"We recently demonstrated that the net accumulation of 3H-norepinephrine in the rat pheochromocytoma cell line PC12 was reduced by anesthetic concentrations of n-alkanols and the volatile anesthetics halothane, enflurane, isoflurane, and methoxyflurane."3.68[Methoxyflurane and ethanol do not inhibit the neuronal uptake of noradrenaline (uptake 1) at the desipramine binding site]. ( Kress, HG; Schömig, E, 1990)
"PC12 pheochromocytoma cells take up 3,4-dihydroxyphenylethylamine (dopamine) and norepinephrine by a Na+-dependent, cocaine-sensitive system."3.67Characterization of xylamine binding to proteins of PC12 pheochromocytoma cells. ( Cho, AK; Howard, BD; Koide, M, 1986)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19909 (64.29)18.7374
1990's4 (28.57)18.2507
2000's1 (7.14)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bayer, M1
Kuçi, Z1
Schömig, E5
Gründemann, D1
Dittmann, H1
Handgretinger, R1
Bruchelt, G1
Bönisch, H5
Achong, MR1
Keane, PM1
Greene, LA1
Rein, G1
Lambert, MT1
Esler, M1
Eisenhofer, G1
Chin, J1
Jennings, G1
Meredith, I1
Cox, H1
Lambert, G1
Thompson, J1
Dart, A1
Martiny-Baron, G1
Blum, B1
Michael-Hepp, J3
Kress, HG1
Schönfeld, CL1
Jaques, S1
Tobes, MC1
Sisson, JC1
Koide, M1
Cho, AK1
Howard, BD1
Harder, R1

Other Studies

14 other studies available for desipramine and Pheochromocytoma, Extra-Adrenal

ArticleYear
Uptake of mIBG and catecholamines in noradrenaline- and organic cation transporter-expressing cells: potential use of corticosterone for a preferred uptake in neuroblastoma- and pheochromocytoma cells.
    Nuclear medicine and biology, 2009, Volume: 36, Issue:3

    Topics: 3-Iodobenzylguanidine; Animals; Biological Transport; Catecholamines; Cell Line, Tumor; Corticostero

2009
The transport of (+)-amphetamine by the neuronal noradrenaline carrier.
    Naunyn-Schmiedeberg's archives of pharmacology, 1984, Volume: 327, Issue:4

    Topics: Adrenal Gland Neoplasms; Animals; Biological Transport; Cell Line; Cocaine; Desipramine; Dextroamphe

1984
Pheochromocytoma unmasked by desipramine therapy.
    Annals of internal medicine, 1981, Volume: 94, Issue:3

    Topics: Adrenal Gland Neoplasms; Desipramine; Female; Hemodynamics; Humans; Middle Aged; Norepinephrine; Phe

1981
Release, storage and uptake of catecholamines by a clonal cell line of nerve growth factor (NGF) responsive pheo-chromocytoma cells.
    Brain research, 1977, Jul-01, Volume: 129, Issue:2

    Topics: Animals; Catecholamines; Cations, Divalent; Clone Cells; Cocaine; Desipramine; Dinitrophenols; Dopam

1977
Pheochromocytoma presenting as exacerbation of post traumatic stress disorder symptomology.
    International journal of psychiatry in medicine, 1992, Volume: 22, Issue:3

    Topics: Adrenal Gland Neoplasms; Adult; Blood Pressure; Combat Disorders; Desipramine; Diagnostic Errors; Ho

1992
Is adrenaline released by sympathetic nerves in man?
    Clinical autonomic research : official journal of the Clinical Autonomic Research Society, 1991, Volume: 1, Issue:2

    Topics: Adrenal Gland Neoplasms; Adult; Catecholamines; Desipramine; Epinephrine; Exercise; Heart Failure; H

1991
Biochemical characterization and purification of the neuronal sodium-dependent noradrenaline transporter.
    Journal of neural transmission. Supplementum, 1990, Volume: 32

    Topics: Adrenal Gland Neoplasms; Adrenal Medulla; Affinity Labels; Animals; Carrier Proteins; Cattle; Cell M

1990
[Methoxyflurane and ethanol do not inhibit the neuronal uptake of noradrenaline (uptake 1) at the desipramine binding site].
    Der Anaesthesist, 1990, Volume: 39, Issue:7

    Topics: Adrenal Gland Neoplasms; Animals; Binding Sites; Biological Transport, Active; Cell Line; Depression

1990
Inhibition of neuronal noradrenaline transport (uptake1) and desipramine binding by amiloride and ethylisopropylamiloride.
    Naunyn-Schmiedeberg's archives of pharmacology, 1989, Volume: 340, Issue:5

    Topics: Amiloride; Animals; Anti-Arrhythmia Agents; Desipramine; Hydrogen-Ion Concentration; Kinetics; Neuro

1989
Solubilization and characterization of the 3H-desipramine binding site of rat phaeochromocytoma cells (PC12-cells).
    Naunyn-Schmiedeberg's archives of pharmacology, 1986, Volume: 334, Issue:4

    Topics: Animals; Binding, Competitive; Carrier Proteins; Cell Membrane; Cells, Cultured; Desipramine; Pheoch

1986
Inhibition of neuronal noradrenaline uptake (uptake1) and desipramine binding by N-ethylmaleimide (NEM).
    Naunyn-Schmiedeberg's archives of pharmacology, 1988, Volume: 337, Issue:6

    Topics: Adrenal Gland Neoplasms; Animals; Cell Membrane; Cells, Cultured; Cocaine; Desipramine; Ethylmaleimi

1988
Sodium dependency of uptake of norepinephrine and m-iodobenzylguanidine into cultured human pheochromocytoma cells: evidence for uptake-one.
    Cancer research, 1987, Aug-01, Volume: 47, Issue:15

    Topics: 3-Iodobenzylguanidine; Adolescent; Adult; Biological Transport, Active; Cells, Cultured; Child; Desi

1987
Characterization of xylamine binding to proteins of PC12 pheochromocytoma cells.
    Journal of neurochemistry, 1986, Volume: 47, Issue:4

    Topics: Adrenal Gland Neoplasms; Animals; Benztropine; Binding, Competitive; Biological Transport; Carrier P

1986
Binding of 3H-desipramine to the neuronal noradrenaline carrier of rat phaeochromocytoma cells (PC-12 cells).
    Naunyn-Schmiedeberg's archives of pharmacology, 1986, Volume: 334, Issue:4

    Topics: Adrenergic Fibers; Animals; Cell Membrane; Cells, Cultured; Desipramine; Kinetics; Nerve Tissue Prot

1986