desipramine has been researched along with Peripheral Nervous System Diseases in 3 studies
Desipramine: A tricyclic dibenzazepine compound that potentiates neurotransmission. Desipramine selectively blocks reuptake of norepinephrine from the neural synapse, and also appears to impair serotonin transport. This compound also possesses minor anticholinergic activity, through its affinity to muscarinic receptors.
desipramine : A dibenzoazepine consisting of 10,11-dihydro-5H-dibenzo[b,f]azepine substituted on nitrogen with a 3-(methylamino)propyl group.
Peripheral Nervous System Diseases: Diseases of the peripheral nerves external to the brain and spinal cord, which includes diseases of the nerve roots, ganglia, plexi, autonomic nerves, sensory nerves, and motor nerves.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Imipramine dose was increased in steps of 25 mg/d every second week, and blood samples were taken at every dose." | 6.71 | TDM-based imipramine treatment in neuropathic pain. ( Bach, FW; Jensen, TS; Rasmussen, PV; Sindrup, SH, 2004) |
| "Imipramine dose was increased in steps of 25 mg/d every second week, and blood samples were taken at every dose." | 2.71 | TDM-based imipramine treatment in neuropathic pain. ( Bach, FW; Jensen, TS; Rasmussen, PV; Sindrup, SH, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hu, B | 1 |
| Doods, H | 1 |
| Treede, RD | 1 |
| Ceci, A | 1 |
| Rasmussen, PV | 1 |
| Jensen, TS | 1 |
| Sindrup, SH | 1 |
| Bach, FW | 1 |
| Benazzi, F | 1 |
| Ciucci, G | 1 |
1 trial available for desipramine and Peripheral Nervous System Diseases
| Article | Year |
|---|---|
TDM-based imipramine treatment in neuropathic pain.
Topics: Adult; Aged; Analgesics, Non-Narcotic; Desipramine; Dose-Response Relationship, Drug; Drug Monitorin | 2004 |
2 other studies available for desipramine and Peripheral Nervous System Diseases
| Article | Year |
|---|---|
Depression-like behaviour in rats with mononeuropathy is reduced by the CB2-selective agonist GW405833.
Topics: Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Behavior, Animal; Depressive Disor | 2009 |
Neuropathy associated with tricyclic antidepressants.
Topics: Alprazolam; Antidepressive Agents, Tricyclic; Desipramine; Female; Humans; Middle Aged; Nortriptylin | 1997 |