desipramine has been researched along with Opioid-Related Disorders in 18 studies
Desipramine: A tricyclic dibenzazepine compound that potentiates neurotransmission. Desipramine selectively blocks reuptake of norepinephrine from the neural synapse, and also appears to impair serotonin transport. This compound also possesses minor anticholinergic activity, through its affinity to muscarinic receptors.
desipramine : A dibenzoazepine consisting of 10,11-dihydro-5H-dibenzo[b,f]azepine substituted on nitrogen with a 3-(methylamino)propyl group.
Opioid-Related Disorders: Disorders related to or resulting from abuse or misuse of OPIOIDS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This 13-week, randomized, double-blind, placebo-controlled trial evaluated the efficacy of desipramine hydrochloride (0 or 150 mg/d) plus buprenorphine hydrochloride (12 mg/d) or methadone hydrochloride (65 mg/d) in 180 opioid-dependent cocaine abusers (124 men, 56 women)." | 9.09 | Desipramine in opioid-dependent cocaine abusers maintained on buprenorphine vs methadone. ( Feingold, A; Jatlow, P; Kosten, TR; Oliveto, AH; Schottenfeld, R, 1999) |
| "This 13-week, randomized, double-blind, placebo-controlled trial evaluated the efficacy of desipramine hydrochloride (0 or 150 mg/d) plus buprenorphine hydrochloride (12 mg/d) or methadone hydrochloride (65 mg/d) in 180 opioid-dependent cocaine abusers (124 men, 56 women)." | 5.09 | Desipramine in opioid-dependent cocaine abusers maintained on buprenorphine vs methadone. ( Feingold, A; Jatlow, P; Kosten, TR; Oliveto, AH; Schottenfeld, R, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (22.22) | 18.7374 |
| 1990's | 9 (50.00) | 18.2507 |
| 2000's | 5 (27.78) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kosten, T | 2 |
| Poling, J | 3 |
| Oliveto, A | 4 |
| Feingold, A | 4 |
| Sevarino, K | 1 |
| McCance-Katz, E | 1 |
| Stine, S | 1 |
| Gonzalez, G | 3 |
| Gonsai, K | 2 |
| Oliveto, AH | 1 |
| Schottenfeld, R | 2 |
| Jatlow, P | 2 |
| Kosten, TR | 8 |
| Sofuoglu, M | 1 |
| Arndt, IO | 3 |
| McLellan, AT | 3 |
| Dorozynsky, L | 3 |
| Woody, GE | 2 |
| O'Brien, CP | 4 |
| Carroll, KM | 1 |
| Rounsaville, BJ | 1 |
| Nich, C | 1 |
| Gordon, L | 1 |
| Gawin, F | 1 |
| Kolar, AF | 1 |
| Brown, BS | 1 |
| Weddington, WW | 1 |
| Haertzen, CC | 1 |
| Michaelson, BS | 1 |
| Jaffe, JH | 1 |
| Brooke, D | 1 |
| Fudala, PJ | 1 |
| Johnson, RE | 1 |
| Morgan, CM | 1 |
| Falcione, J | 1 |
| Schottenfeld, RS | 2 |
| Morgan, CH | 1 |
| Gawin, FH | 2 |
| Morgan, C | 1 |
| Nelson, JC | 1 |
| Maany, I | 1 |
| Dhopesh, V | 1 |
| Burke, W | 1 |
| Woody, G | 2 |
| Arndt, I | 1 |
| Mendelson, JH | 1 |
| Mello, NK | 1 |
| Schumann, B | 1 |
| Wright, D | 1 |
| Carney, MK | 1 |
1 review available for desipramine and Opioid-Related Disorders
| Article | Year |
|---|---|
Clinical investigations of drug effects in women.
Topics: Buprenorphine; Cocaine; Desipramine; Female; Heroin Dependence; Humans; Male; Naltrexone; Opioid-Rel | 1986 |
14 trials available for desipramine and Opioid-Related Disorders
| Article | Year |
|---|---|
Effects of reducing contingency management values on heroin and cocaine use for buprenorphine- and desipramine-treated patients.
Topics: Adult; Antidepressive Agents, Tricyclic; Behavior Control; Buprenorphine; Cocaine-Related Disorders; | 2003 |
Desipramine and contingency management for cocaine and opiate dependence in buprenorphine maintained patients.
Topics: Adult; Aged; Ambulatory Care; Analysis of Variance; Antidepressive Agents, Tricyclic; Buprenorphine; | 2003 |
Desipramine in opioid-dependent cocaine abusers maintained on buprenorphine vs methadone.
Topics: Adult; Analgesics, Opioid; Antidepressive Agents, Tricyclic; Buprenorphine; Cocaine-Related Disorder | 1999 |
Comorbid major depressive disorder as a prognostic factor in cocaine-abusing buprenorphine-maintained patients treated with desipramine and contingency management.
Topics: Adult; Aged; Antidepressive Agents, Tricyclic; Buprenorphine; Cocaine-Related Disorders; Comorbidity | 2003 |
Prediction of treatment outcome by baseline urine cocaine results and self-reported cocaine use for cocaine and opioid dependence.
Topics: Adult; Analysis of Variance; Antidepressive Agents, Tricyclic; Buprenorphine; Cocaine-Related Disord | 2003 |
Desipramine treatment for cocaine dependence. Role of antisocial personality disorder.
Topics: Adult; Antisocial Personality Disorder; Cocaine; Comorbidity; Desipramine; Humans; Male; Methadone; | 1994 |
Integrating psychotherapy and pharmacotherapy for cocaine dependence: results from a randomized clinical trial.
Topics: Adult; Antidepressive Agents, Tricyclic; Cocaine; Cognitive Behavioral Therapy; Combined Modality Th | 1995 |
Utility of crossover designs in clinical trials: efficacy of desipramine vs. placebo in opioid-dependent cocaine abusers.
Topics: Adult; Analgesics, Opioid; Antidepressive Agents, Tricyclic; Buprenorphine; Clinical Trials as Topic | 2002 |
Treatment of cocaine dependence in methadone maintenance clients: a pilot study comparing the efficacy of desipramine and amantadine.
Topics: Adolescent; Adult; Amantadine; Baltimore; Cocaine; Desipramine; Female; Follow-Up Studies; Humans; M | 1992 |
Weighing up the pros and cons: help-seeking by drug misusers in Baltimore, USA.
Topics: Adult; Bromocriptine; Buprenorphine; Cocaine; Desipramine; Fear; Female; Fluoxetine; Humans; Male; M | 1992 |
Desipramine treatment of cocaine dependence in methadone-maintained patients.
Topics: Adult; Cocaine; Comorbidity; Desipramine; Double-Blind Method; Drug Therapy, Combination; Follow-Up | 1992 |
Pharmacotherapy for cocaine-abusing methadone-maintained patients using amantadine or desipramine.
Topics: Adult; Amantadine; Cocaine; Desipramine; Double-Blind Method; Female; Humans; Male; Methadone; Opioi | 1992 |
Amantadine and desipramine in the treatment of cocaine abusing methadone maintained patients.
Topics: Adult; Amantadine; Cocaine; Desipramine; Double-Blind Method; Female; Humans; Male; Methadone; Opioi | 1990 |
Desipramine treatment of cocaine abuse in methadone maintenance patients.
Topics: Clinical Trials as Topic; Cocaine; Combined Modality Therapy; Desipramine; Double-Blind Method; Huma | 1989 |
3 other studies available for desipramine and Opioid-Related Disorders
| Article | Year |
|---|---|
Desipramine and its 2-hydroxy metabolite in patients taking or not taking methadone.
Topics: Desipramine; Drug Interactions; Humans; Hydroxylation; Methadone; Opioid-Related Disorders | 1990 |
Increase in desipramine serum levels associated with methadone treatment.
Topics: Adult; Cocaine; Desipramine; Drug Interactions; Drug Therapy, Combination; Humans; Male; Methadone; | 1989 |
A preliminary study of desipramine in the treatment of cocaine abuse in methadone maintenance patients.
Topics: Adult; Antisocial Personality Disorder; Black or African American; Cocaine; Desipramine; Female; Hum | 1987 |