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desipramine and Neuralgia, Postherpetic

desipramine has been researched along with Neuralgia, Postherpetic in 3 studies

Desipramine: A tricyclic dibenzazepine compound that potentiates neurotransmission. Desipramine selectively blocks reuptake of norepinephrine from the neural synapse, and also appears to impair serotonin transport. This compound also possesses minor anticholinergic activity, through its affinity to muscarinic receptors.
desipramine : A dibenzoazepine consisting of 10,11-dihydro-5H-dibenzo[b,f]azepine substituted on nitrogen with a 3-(methylamino)propyl group.

Neuralgia, Postherpetic: Pain in nerves, frequently involving facial SKIN, resulting from the activation the latent varicella-zoster virus (HERPESVIRUS 3, HUMAN). The two forms of the condition preceding the pain are HERPES ZOSTER OTICUS; and HERPES ZOSTER OPHTHALMICUS. Following the healing of the rashes and blisters, the pain sometimes persists.

Research Excerpts

ExcerptRelevanceReference
"Desipramine was more effective and less expensive than gabapentin or pregabalin (dominant) under all conditions tested."6.44A cost-effectiveness comparison of desipramine, gabapentin, and pregabalin for treating postherpetic neuralgia. ( Holloway, RG; Noyes, K; O'Connor, AB, 2007)
"In 47 patients with postherpetic neuralgia (PHN) who had never had an adequate trial of any antidepressant, we performed a randomized, double-blind, parallel design trial comparing desipramine, amitriptyline, and fluoxetine."5.11Treatment response in antidepressant-naïve postherpetic neuralgia patients: double-blind, randomized trial. ( Davies, PS; Fields, HL; Reisner, LA; Rowbotham, MC, 2005)
"Desipramine was more effective and less expensive than gabapentin or pregabalin (dominant) under all conditions tested."2.44A cost-effectiveness comparison of desipramine, gabapentin, and pregabalin for treating postherpetic neuralgia. ( Holloway, RG; Noyes, K; O'Connor, AB, 2007)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (66.67)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hearn, L1
Moore, RA1
Derry, S1
Wiffen, PJ1
Phillips, T1
Rowbotham, MC1
Reisner, LA1
Davies, PS1
Fields, HL1
O'Connor, AB1
Noyes, K1
Holloway, RG1

Reviews

2 reviews available for desipramine and Neuralgia, Postherpetic

ArticleYear
Desipramine for neuropathic pain in adults.
    The Cochrane database of systematic reviews, 2014, Sep-23, Issue:9

    Topics: Aged; Amitriptyline; Analgesics; Antidepressive Agents, Tricyclic; Chronic Pain; Clomipramine; Desip

2014
A cost-effectiveness comparison of desipramine, gabapentin, and pregabalin for treating postherpetic neuralgia.
    Journal of the American Geriatrics Society, 2007, Volume: 55, Issue:8

    Topics: Aged; Amines; Analgesics; Antidepressive Agents, Tricyclic; Cost-Benefit Analysis; Cyclohexanecarbox

2007

Trials

1 trial available for desipramine and Neuralgia, Postherpetic

ArticleYear
Treatment response in antidepressant-naïve postherpetic neuralgia patients: double-blind, randomized trial.
    The journal of pain, 2005, Volume: 6, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Amitriptyline; Antidepressive Agents, Second-Generation; Antidepress

2005