desipramine has been researched along with Muscle Contraction in 105 studies
Desipramine: A tricyclic dibenzazepine compound that potentiates neurotransmission. Desipramine selectively blocks reuptake of norepinephrine from the neural synapse, and also appears to impair serotonin transport. This compound also possesses minor anticholinergic activity, through its affinity to muscarinic receptors.
desipramine : A dibenzoazepine consisting of 10,11-dihydro-5H-dibenzo[b,f]azepine substituted on nitrogen with a 3-(methylamino)propyl group.
Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
| Excerpt | Relevance | Reference |
|---|---|---|
| " However, it is also known to accumulate in various tissues up to several times higher after standard oral dosing and we now have evidence from both in vivo and in vitro experiments with spontaneously hypertensive rats (SHR) that millimolar levels stimulate release of norepinephrine (NE) from vascular sympathetic nerve endings (SNEs)." | 1.31 | A possible indirect sympathomimetic action of metformin in the arterial vessel wall of spontanously hypertensive rats. ( Lee, JM; Peuler, JD, 2001) |
| "5." | 1.28 | Nerve-mediated contractions of sheep mesenteric lymph node capsules. ( Allen, JM; Hughes, G; McHale, NG; Thornbury, KD, 1990) |
| " These results show that the adaptative changes of alpha-adrenoceptors in the rat anococcygeus muscle following long-term administration may depend on the efficiency to inhibit the neuronal uptake and the ability to antagonize alpha 1-adrenoceptors." | 1.28 | Effects of chronic antidepressant treatment on alpha 1- and alpha 2-adrenoceptors in the rat anococcygeus muscle. ( Badia, A; Sallés, J; Vila, E, 1990) |
| " Twenty-four hours after a single dose of desipramine (10 mg/kg, intraperitoneally) the inhibitory dose-response curves to either UK 14 304 or desipramine itself did not differ significantly from those seen in control animals, whereas both were displaced significantly to the right after 15 days pretreatment with desipramine." | 1.27 | Effects of desipramine on stimulation-induced contractions of the vas deferens of rats pretreated either chronically with desipramine or acutely with idazoxan. ( Doxey, JC; Roach, AG; Samuel, J, 1985) |
| "Nisoxetine was also less potent than desipramine in inhibiting responses to histamine, carbachol and bradykinin on the guinea-pig isolated ileum." | 1.27 | Some pharmacological actions of nisoxetine, a bicyclic inhibitor of noradrenaline uptake. ( Foley, AJ; Leedham, JA; Pennefather, JN, 1985) |
| " Chronic administration of amitriptyline and desipramine blocked PGE2-induced hypomotility in the mouse." | 1.27 | Tricyclic antidepressants antagonize prostaglandin (PG) E2-induced contractions of the guinea pig ileum and hypomotility in the mouse. ( Tayo, FM, 1985) |
| "Desipramine-pretreated thoracic aortas were contracted to a steady-state of 1-2 g with norepinephrine and immersed in mineral oil to prevent diffusion of drugs from the tissue." | 1.26 | Vasoconstrictor effects of aldosterone in isolated vascular tissue. ( Drayer, JI; Purdy, RE; Weber, MA, 1982) |
| " Dose-response curves to norepinephrine were shifted to the left by factors of 4." | 1.26 | Effects of reserpinization, surgical denervation and in vitro chemical denervation with 6-hydroxydopamine on the contractile response of isolated rabbit ear artery to propranolol. ( Ashbrook, DW; Hurlbut, DE; Purdy, RE; Reidy, JP; Stratford, RE; Watanabe, MY, 1981) |
| "Reserpine pretreatment almost abolished the response and after-response." | 1.26 | The isolated circular muscle layer of the vas deferens of the guinea-pig. ( Anstey, MD; Birmingham, AT, 1980) |
| " This behavioral syndrome, characterized by tremor and muscle twitches (myoclonus), showed a clear dose-response relationship with 5,7-DHT as well as with 5-HTP." | 1.26 | Inhibition of 5,7-dihydroxytryptamine-induced supersensitivity to 5-hydroxytryptophan in mice by treatment with cycloheximide. ( Baldessarini, RJ; Campbell, A; Sperk, G; Stewart, RM, 1978) |
| " Cocaine (2 x 10(-6) M and 10(-5) M) produced 2 and 7 fold shifts to the left of the dose-response curve to (-)-noradrenaline recorded isotonically in isolated splenic capsular strips of the cat." | 1.26 | Investigation of the role of calcium in the supersensitivity produced by cocaine in cat spleen strips. ( Summers, RJ; Tillman, J, 1979) |
| " Low concentrations of (--)-cocaine or its stereoisomer, (4)-pseudococaine, produced shifts to the right of the 5-HT dose-response curves on heart and ileum with no depression of the maximum responses to electrical stimulation or dimethylphenylpiperazinium remained unaffected." | 1.26 | Blockade of serotonin receptors on autonomic neurones by (-)-cocaine and some related compounds. ( Fozard, JR; Mobarok Ali, AT; Newgrosh, G, 1979) |
| "Pre-treatment with debrisoquine (0." | 1.26 | The sympathomimetic activity of fenfluramine hydrochloride on rat vas deferens. ( Mottram, DR; Wadhwani, D, 1977) |
| "The effect of desipramine on the cumulative dose-response curves of noradrenaline and potassium (K+) was examined on the isolated rat vas deferens." | 1.26 | Persistent enhancement of potassium-induced responses of the rat vas deferens by desipramine. ( Schneider, D; Swamy, VC, 1976) |
| " Both drugs also shift to the left the dose-response curves for noradrenaline and adrenaline on isolated strips, cocaine being most potent." | 1.26 | Uptake and release of catecholamines in sympathetic nerve fibres in the spleen of the cod, Gadus morhua. ( Holmgren, S; Nilsson, S, 1976) |
| "In cumulative dose-response studies, strips from bladder neck of rabbit were significantly more sensitive to stimulation with noradrenaline, phenylephrine, and methoxamine than were strips from detrusor." | 1.25 | A difference in sensitivity to alpha-adrenergic agonists exhibited by detrusor and bladder neck of rabbit. ( Awad, SA; Carro-Ciampi, G; Dean, DM; Downie, JW, 1975) |
| "Pretreatment with phenoxybenzamine, piperoxane or cocaine further increased catecholamine excretion, but desipramine caused only a small increase in catecholamine excretion which did not correlate with its effect on dye extravasation." | 1.25 | Role of endogenous catecholamines in the anti-inflammatory activity of alpha-adrenoceptor blocking agents. ( Green, KL, 1974) |
| " The difference in sensitivity was greater in the lower than the upper parts of the dose-response curves." | 1.25 | Differences in sensitivity to vasoconstrictor drugs within the wall of the sheep carotid artery. ( Graham, JM; Keatinge, WR, 1972) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 88 (83.81) | 18.7374 |
| 1990's | 8 (7.62) | 18.2507 |
| 2000's | 6 (5.71) | 29.6817 |
| 2010's | 2 (1.90) | 24.3611 |
| 2020's | 1 (0.95) | 2.80 |
| Authors | Studies |
|---|---|
| Britto-Júnior, J | 1 |
| da Silva-Filho, WP | 1 |
| Amorim, AC | 1 |
| Campos, R | 1 |
| Moraes, MO | 1 |
| Moraes, MEA | 1 |
| Fregonesi, A | 1 |
| Monica, FZ | 1 |
| Antunes, E | 1 |
| De Nucci, G | 1 |
| Docherty, JR | 2 |
| Parker, LK | 1 |
| Shanks, JA | 1 |
| Kennard, JA | 1 |
| Brain, KL | 1 |
| Hague, C | 1 |
| Gonzalez-Cabrera, PJ | 1 |
| Jeffries, WB | 1 |
| Abel, PW | 1 |
| Jimenez-Altayo, F | 1 |
| Giraldo, J | 1 |
| McGrath, JC | 1 |
| Vila, E | 2 |
| Koella, WP | 1 |
| Rubin, R | 1 |
| Schaeppi, U | 1 |
| Doggrell, SA | 2 |
| Waldron, JB | 1 |
| Park, BK | 1 |
| Haynes, BP | 1 |
| Sheridan, SA | 1 |
| Nowell, PT | 1 |
| Ennis, C | 1 |
| Lattimer, N | 1 |
| Koga, Y | 1 |
| Downes, H | 1 |
| Taylor, SM | 1 |
| Pommier, Y | 1 |
| Andréjak, M | 1 |
| Mouillé, P | 1 |
| Dabiré, H | 1 |
| Lucet, B | 1 |
| Schmitt, H | 1 |
| Archer, T | 1 |
| Cotic, T | 1 |
| Järbe, TU | 1 |
| Greden, JF | 1 |
| Price, HL | 1 |
| Genero, N | 1 |
| Feinberg, M | 1 |
| Levine, S | 1 |
| Levin, RM | 1 |
| Staskin, DR | 1 |
| Wein, AJ | 1 |
| Bengtsson, B | 2 |
| Marshall, JM | 1 |
| Purdy, RE | 3 |
| Weber, MA | 1 |
| Drayer, JI | 1 |
| Kenakin, TP | 1 |
| Beek, D | 1 |
| Ashbrook, DW | 1 |
| Hurlbut, DE | 1 |
| Reidy, JP | 1 |
| Stratford, RE | 1 |
| Watanabe, MY | 1 |
| Sánchez, S | 1 |
| Planas, ME | 1 |
| Valdecasas, FG | 1 |
| Pascual, R | 1 |
| Bevan, JA | 5 |
| Anstey, MD | 1 |
| Birmingham, AT | 1 |
| Gwee, MC | 2 |
| Cheah, LS | 1 |
| Shoon, ML | 1 |
| Sharma, A | 1 |
| Kulkarni, SK | 1 |
| Gong, JP | 1 |
| Gopalakrishnakone, P | 1 |
| Fernández del Pozo, B | 1 |
| Pérez-Vizcaíno, F | 1 |
| Fernández, C | 1 |
| Zaragozá, F | 1 |
| Tamargo, J | 1 |
| Najbar-Kaszkiel, AT | 1 |
| Rand, MJ | 1 |
| Busch, L | 1 |
| Wald, M | 1 |
| Sterin-Borda, L | 1 |
| Borda, E | 1 |
| Sántha, E | 1 |
| Sperlágh, B | 1 |
| Zelles, T | 1 |
| Zsilla, G | 1 |
| Tóth, PT | 1 |
| Lendvai, B | 1 |
| Baranyi, M | 1 |
| Vizi, ES | 1 |
| Rajamani, K | 1 |
| Leong, S | 1 |
| Lavelle, A | 1 |
| Lee, JM | 1 |
| Peuler, JD | 1 |
| Chiou, CY | 1 |
| Trzeciakowski, J | 1 |
| Bevan, RD | 1 |
| Chang, PC | 1 |
| Pegram, BL | 1 |
| Su, C | 4 |
| Eccles, R | 2 |
| MacLean, AG | 2 |
| Downie, JW | 1 |
| Dean, DM | 1 |
| Carro-Ciampi, G | 1 |
| Awad, SA | 1 |
| Tseng, LF | 2 |
| Sperk, G | 1 |
| Stewart, RM | 1 |
| Campbell, A | 1 |
| Baldessarini, RJ | 1 |
| Summers, RJ | 1 |
| Tillman, J | 1 |
| Tayo, FM | 3 |
| Fozard, JR | 1 |
| Mobarok Ali, AT | 1 |
| Newgrosh, G | 1 |
| Verbeuren, TJ | 1 |
| Vanhoutte, PM | 1 |
| Mottram, DR | 1 |
| Wadhwani, D | 1 |
| Batmanglidj Eckhardt, S | 1 |
| Maxwell, RA | 2 |
| Copp, FC | 1 |
| Petersen, EN | 1 |
| Olsson, SO | 1 |
| Squires, RF | 1 |
| Huston, LJ | 1 |
| Golko, DS | 1 |
| Paton, DM | 3 |
| Keatinge, WR | 3 |
| Torrie, C | 1 |
| Schneider, D | 1 |
| Swamy, VC | 1 |
| Nilsson, S | 1 |
| Holmgren, S | 1 |
| Biamino, G | 1 |
| Nöring, J | 1 |
| Neye, G | 1 |
| Neye, J | 1 |
| Johns, A | 2 |
| Lee, TJ | 1 |
| Wannan, G | 1 |
| Prior, C | 1 |
| Marshall, IG | 1 |
| Thornbury, KD | 1 |
| McHale, NG | 1 |
| Allen, JM | 1 |
| Hughes, G | 1 |
| Sallés, J | 1 |
| Badia, A | 1 |
| Mikami, H | 1 |
| Ogihara, T | 1 |
| Ohde, H | 1 |
| Katahira, K | 1 |
| Kohara, K | 1 |
| Kumahara, Y | 1 |
| Godfrey, PP | 1 |
| McClue, SJ | 1 |
| Young, MM | 1 |
| Heal, DJ | 1 |
| Doxey, JC | 1 |
| Roach, AG | 1 |
| Samuel, J | 1 |
| Bradley, L | 1 |
| Finberg, JP | 1 |
| Tal, A | 1 |
| Leedham, JA | 1 |
| Foley, AJ | 1 |
| Pennefather, JN | 1 |
| Cheng, JT | 1 |
| Shen, CL | 1 |
| Brock, JA | 1 |
| Cunnane, TC | 1 |
| Muth, EA | 1 |
| Haskins, JT | 1 |
| Moyer, JA | 1 |
| Husbands, GE | 1 |
| Nielsen, ST | 1 |
| Sigg, EB | 1 |
| Sorvino, AR | 1 |
| Chinn, C | 1 |
| Weber, LJ | 1 |
| Green, KL | 1 |
| Baltzer, V | 1 |
| Bein, HJ | 1 |
| Chang, CC | 2 |
| Tang, SS | 1 |
| Turker, RK | 1 |
| Khairallah, PA | 1 |
| Graham, JM | 2 |
| Toda, N | 4 |
| Chuang, ST | 1 |
| Hrdina, P | 1 |
| Garattini, S | 2 |
| Day, MD | 1 |
| Owen, DA | 1 |
| Warren, PR | 1 |
| Bouquet, J | 1 |
| Noach, EL | 1 |
| Oxenkrug, GF | 1 |
| Lapin, IP | 1 |
| Farnebo, LO | 1 |
| Malamfors, T | 1 |
| Khoyi, MA | 1 |
| Pousti, A | 1 |
| Zarrindast, MR | 1 |
| Stjärne, L | 1 |
| Kuchii, M | 1 |
| Shibata, S | 1 |
| Mori, J | 1 |
| Krishnamurty, VS | 1 |
| Grollman, A | 1 |
| Atkinson, R | 1 |
| Watkinson, B | 1 |
| Weetman, DF | 1 |
| Atkinson, J | 1 |
| Ladinsky, H | 1 |
| Wand, H | 1 |
| Sinha, JN | 1 |
| Jaju, BP | 1 |
| Srimal, RC | 1 |
| Eckhardt, SB | 1 |
| Hite, G | 1 |
| Vohra, MM | 1 |
| Hrdina, PD | 1 |
| Ling, GM | 1 |
| Dyer, DC | 1 |
| Binini, R | 1 |
| Bonaccorsi, A | 1 |
| Morselli, PL | 1 |
| Muscettola, GB | 1 |
| Shimamoto, K | 1 |
| Matsuo, S | 1 |
| Barnett, A | 1 |
| Greenhouse, DD | 1 |
| Taber, RI | 1 |
| Govier, WC | 1 |
| Sugrue, MF | 1 |
| Shore, PA | 1 |
| Scriabine, A | 1 |
| Laddu, AR | 1 |
| Somani, P | 1 |
105 other studies available for desipramine and Muscle Contraction
| Article | Year |
|---|---|
6-nitrodopamine is a major endogenous modulator of human vas deferens contractility.
Topics: Adrenergic Antagonists; Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Carbamazepine; Chr | 2022 |
Effects of desipramine on prazosin potency at α1A- and α1D-adrenoceptors in rat vas deferens: implications for the α1L-adrenoceptor subclassification.
Topics: Animals; Cocaine; Desipramine; Male; Muscle Contraction; Norepinephrine; Prazosin; Rats; Rats, Wista | 2014 |
Dynamic monitoring of NET activity in mature murine sympathetic terminals using a fluorescent substrate.
Topics: Adrenergic Fibers; Adrenergic Uptake Inhibitors; Amphetamine; Animals; Choline O-Acetyltransferase; | 2010 |
Relationship between alpha(1)-adrenergic receptor-induced contraction and extracellular signal-regulated kinase activation in the bovine inferior alveolar artery.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Cattle; Desipramine; Enzyme Activa | 2002 |
Enhanced noradrenergic transmission in the spontaneously hypertensive rat anococcygeus muscle.
Topics: Animals; Blotting, Western; Carbachol; Desipramine; Dose-Response Relationship, Drug; Electric Stimu | 2003 |
Effects of serotonin upon the isolated iris sphincter of the cat.
Topics: Acetylcholine; Animals; Atropine; Cats; Creatine; Desipramine; Electric Stimulation; Electrophysiolo | 1967 |
Effect of cocaine on tone and contractile responses to acetylcholine in the rat anococcygeus muscle.
Topics: Acetylcholine; Animals; Atropine; Cocaine; Desipramine; Drug Interactions; Male; Muscle Contraction; | 1982 |
Stereoselectivity of catecholamines: differential effects of cocaine and desipramine on catecholamine-induced contractions of the rat isolated vas deferens.
Topics: Animals; Catecholamines; Cocaine; Desipramine; In Vitro Techniques; Male; Muscle Contraction; Muscle | 1983 |
Presynaptic agonist effect of phentolamine in the rabbit vas deferens and rat cerebral cortex.
Topics: Animals; Brain Chemistry; Cerebral Cortex; Desipramine; In Vitro Techniques; Indoramin; Male; Muscle | 1984 |
Direct and indirect actions of dopamine on tracheal smooth muscle.
Topics: Animals; Desipramine; Dopamine; Dose-Response Relationship, Drug; Guinea Pigs; In Vitro Techniques; | 1980 |
Interaction between mianserin and clonidine at alpha 2-adrenoceptors.
Topics: Animals; Blood Pressure; Chickens; Clonidine; Desipramine; Dibenzazepines; Dogs; Drug Interactions; | 1982 |
Attenuation of the context effect and lack of unconditioned stimulus-preexposure effect in taste-aversion learning following treatment with DSP4, the selective noradrenaline neurotoxin.
Topics: Amines; Animals; Association Learning; Avoidance Learning; Benzylamines; Chlorides; Conditioning, Cl | 1982 |
Facial EMG activity levels predict treatment outcome in depression.
Topics: Amitriptyline; Antidepressive Agents; Bipolar Disorder; Depressive Disorder; Desipramine; Electromyo | 1984 |
Analysis of the anticholinergic and musculotropic effects of desmethylimipramine on the rabbit urinary bladder.
Topics: Animals; Atropine; Bethanechol Compounds; Desipramine; Male; Muscle Contraction; Muscle Relaxation; | 1983 |
Estrogen inhibition of noradrenaline release in the rabbit oviduct.
Topics: Adrenergic Fibers; Animals; Calcium; Castration; Desipramine; Electric Stimulation; Estradiol; Fallo | 1983 |
Vasoconstrictor effects of aldosterone in isolated vascular tissue.
Topics: Aldosterone; Animals; Aorta, Thoracic; Arteries; Desipramine; Desoxycorticosterone; Muscle Contracti | 1982 |
The measurement of antagonist potency and the importance of selective inhibition of agonist uptake processes.
Topics: Albuterol; Amitriptyline; Animals; Desipramine; Guinea Pigs; In Vitro Techniques; Isoproterenol; Mal | 1981 |
Effects of reserpinization, surgical denervation and in vitro chemical denervation with 6-hydroxydopamine on the contractile response of isolated rabbit ear artery to propranolol.
Topics: Animals; Arteries; Denervation; Desipramine; Dose-Response Relationship, Drug; Ear; Hydroxydopamines | 1981 |
[Effect of bretylium on the isolated vas deferens of the rat. Interaction with other drugs].
Topics: Animals; Bretylium Compounds; Cocaine; Desipramine; Male; Muscle Contraction; Muscle, Smooth; Rats; | 1981 |
Asymmetry of consequences of drug disposition mechanisms in the wall of the rabbit aorta.
Topics: Animals; Aorta, Thoracic; Biological Transport; Desipramine; Desoxycorticosterone; Dose-Response Rel | 1980 |
The isolated circular muscle layer of the vas deferens of the guinea-pig.
Topics: Acetylcholine; Animals; Cocaine; Desipramine; Electric Stimulation; Guinea Pigs; In Vitro Techniques | 1980 |
Prejunctional and postjunctional inhibition of adrenergic transmission in the rat-isolated anococcygeus muscle by cimetidine.
Topics: Animals; Cimetidine; Desipramine; Electric Stimulation; Guanethidine; In Vitro Techniques; Male; Mus | 1995 |
On the characterization of dopamine-induced contractile response of rat anococcygeus muscle preparation.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Azepines; Benzazepines; Desipra | 1994 |
Buthus martensi karsch venom: prejunctional adrenergic activity in the rat isolated anococcygeus muscle.
Topics: Animals; Desipramine; Electric Stimulation; Guanethidine; In Vitro Techniques; Injections, Subcutane | 1995 |
Effects of several class I antiarrhythmic drugs on isolated rat aortic vascular smooth muscle.
Topics: Animals; Anti-Arrhythmia Agents; Aorta; Desipramine; Disopyramide; Flecainide; Imipramine; In Vitro | 1997 |
Effects of P2-receptor agonists on sympathetic neuroeffector transmission in the rat isolated anococcygeus muscle.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Desipramine; Electric Stimulation; Enzyme In | 1998 |
Fluoxetine modulates norepinephrine contractile effect on rat vas deferens.
Topics: Animals; Calcium; Cocaine; Desipramine; Dose-Response Relationship, Drug; Fluoxetine; In Vitro Techn | 2000 |
Multiple cellular mechanisms mediate the effect of lobeline on the release of norepinephrine.
Topics: Animals; Calcium; Calcium Channels; Desipramine; Guinea Pigs; Lobeline; Male; Muscle Contraction; Ni | 2000 |
Prejunctional actions of methylenedioxymethamphetamine in vas deferens from wild-type and alpha(2A/D)-adrenoceptor knockout mice.
Topics: Adrenergic Agents; Adrenergic alpha-Agonists; Adrenergic Uptake Inhibitors; Animals; Desipramine; Do | 2001 |
A possible indirect sympathomimetic action of metformin in the arterial vessel wall of spontanously hypertensive rats.
Topics: Animals; Antidepressive Agents; Arteries; Autonomic Fibers, Postganglionic; Desipramine; Drug Intera | 2001 |
Histamine mediation of nicotine effects on postganglionic sympathetic neuroeffector junctions.
Topics: Acetyl-CoA C-Acetyltransferase; Animals; Autonomic Fibers, Postganglionic; Chlorpheniramine; Desipra | 1976 |
Changes in the contractile response of arteires and veins from hypertensive rabbits to sympathetic nerve activity: assessment of some postsynaptic influences.
Topics: Animals; Aorta, Abdominal; Blood Pressure; Blood Vessels; Carotid Arteries; Catechol O-Methyltransfe | 1976 |
Relaxation of smooth muscle following contraction elicited by sympathetic nerve stimulation in vivo.
Topics: Animals; Cats; Cocaine; Desipramine; Electric Stimulation; Female; Male; Methods; Muscle Contraction | 1977 |
A difference in sensitivity to alpha-adrenergic agonists exhibited by detrusor and bladder neck of rabbit.
Topics: Adrenergic alpha-Agonists; Animals; Depression, Chemical; Desipramine; Female; In Vitro Techniques; | 1975 |
Blockade of para-methoxyamphetamine induced serotonin release by serotonin uptake inhibitors.
Topics: Amphetamines; Animals; Brain; Clomipramine; Desipramine; Fluoxetine; Hydroxyindoleacetic Acid; Male; | 1978 |
Inhibition of 5,7-dihydroxytryptamine-induced supersensitivity to 5-hydroxytryptophan in mice by treatment with cycloheximide.
Topics: 5-Hydroxytryptophan; 5,7-Dihydroxytryptamine; Animals; Brain; Cycloheximide; Desipramine; Dihydroxyt | 1978 |
Hydroxytryptamine uptake inhibitors block para- methoxyamphetamine-induced 5-HT release.
Topics: Amphetamines; Animals; Clomipramine; Desipramine; Dose-Response Relationship, Drug; Fluoxetine; Male | 1979 |
Investigation of the role of calcium in the supersensitivity produced by cocaine in cat spleen strips.
Topics: Angiotensin II; Animals; Calcium; Cats; Chlorpheniramine; Cocaine; Desipramine; Drug Interactions; F | 1979 |
Effects of nomifensine on the isolated vas deferens of the rat.
Topics: Animals; Desipramine; Dopamine; Drug Interactions; Guanethidine; In Vitro Techniques; Isoquinolines; | 1979 |
Blockade of serotonin receptors on autonomic neurones by (-)-cocaine and some related compounds.
Topics: Animals; Autonomic Nervous System; Cocaine; Desipramine; Dimethylphenylpiperazinium Iodide; Female; | 1979 |
A comparison of the effect of cocaine desipramine on the contractions of the isolated vas deferens of the rat induced by dopamine and noradrenaline [proceedings].
Topics: Animals; Cocaine; Desipramine; Dopamine; Drug Interactions; In Vitro Techniques; Male; Muscle Contra | 1977 |
The influence of an extraneuronal compartment on the relaxation of the cat nictitating membrane in vivo.
Topics: Animals; Catechol O-Methyltransferase Inhibitors; Cats; Desipramine; Electric Stimulation; Female; M | 1978 |
Effect of blockade of neuronal uptake on the evoked release of 3-H-norepinephrine in the saphenous vein of the dog.
Topics: Animals; Blood Vessels; Cocaine; Desipramine; Dogs; In Vitro Techniques; Muscle Contraction; Neurons | 1978 |
Estrogen induced inhibition of 3H-noradrenaline release in the uterus and portal vein of the rat.
Topics: Animals; Calcium; Castration; Desipramine; Estradiol; Female; Muscle Contraction; Muscle, Smooth; No | 1978 |
The sympathomimetic activity of fenfluramine hydrochloride on rat vas deferens.
Topics: Animals; Debrisoquin; Desipramine; Drug Interactions; Fenfluramine; In Vitro Techniques; Male; Muscl | 1977 |
Influence of desipramine on the uptake and efflux of radiolabelled bretylium and bethanidine in the adventitial and media-intimal layers of rabbit aortic strips.
Topics: Animals; Aorta; Arteries; Bethanidine; Bretylium Compounds; Desipramine; Electric Stimulation; Femal | 1977 |
Effects of 5HT uptake inhibitors on the pressor response to 5HT in the pithed rat. The significance of the 5HT blocking property.
Topics: Animals; Anisoles; Blood Pressure; Chlorpheniramine; Desipramine; Drug Synergism; Imipramine; Male; | 1977 |
Effect of neuronal uptake inhibitors on the adrenergic-neuron blockade produced by guanethidine in rabbit vas deferens.
Topics: Animals; Cocaine; Desipramine; Drug Interactions; Electric Stimulation; Guanethidine; In Vitro Techn | 1977 |
Action of sympathetic nerves of inner and outer muscle of sheep carotid artery, and effect of pressure on nerve distribution.
Topics: Action Potentials; Animals; Carotid Arteries; Cyanides; Desipramine; In Vitro Techniques; Muscle Con | 1976 |
Persistent enhancement of potassium-induced responses of the rat vas deferens by desipramine.
Topics: Animals; Desipramine; Drug Synergism; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; | 1976 |
Uptake and release of catecholamines in sympathetic nerve fibres in the spleen of the cod, Gadus morhua.
Topics: Amphetamine; Animals; Carbachol; Catecholamines; Cocaine; Denervation; Desipramine; Electric Stimula | 1976 |
[Proceedings: Effect of tricyclic antidepressive agents and of Nomifensin (Hoe984) on the contractile properties of the isolated papillary muscle and on the tonus of the smooth vascular muscles].
Topics: Acridines; Animals; Anthracenes; Antidepressive Agents, Tricyclic; Cats; Desipramine; Imipramine; Is | 1975 |
The effect of cocaine, desipramine, 6-hydroxydopamine and indomethacin on the sensitivity of the estrogen-dominated ampulla of rabbit oviduct to (-)-norepinephrine.
Topics: Animals; Cocaine; Desipramine; Drug Synergism; Female; Hydroxydopamines; Indomethacin; Muscle Contra | 1976 |
Neurogenic sympathetic vasoconstriction of the rabbit basilar artery.
Topics: Animals; Basilar Artery; Bretylium Tosylate; Cerebrovascular Circulation; Cocaine; Desipramine; Fema | 1976 |
Alpha-adrenoceptor blocking properties of vesamicol.
Topics: Adrenergic alpha-Antagonists; Animals; Clonidine; Corticosterone; Desipramine; Dioxanes; Electric St | 1991 |
Nerve-mediated contractions of sheep mesenteric lymph node capsules.
Topics: Adrenergic alpha-Antagonists; Animals; Atropine; Desipramine; In Vitro Techniques; Isometric Contrac | 1990 |
Effects of chronic antidepressant treatment on alpha 1- and alpha 2-adrenoceptors in the rat anococcygeus muscle.
Topics: Animals; Antidepressive Agents; Cocaine; Desipramine; Electric Stimulation; Male; Mianserin; Muscle | 1990 |
Direct vascular effects of 19-hydroxyandrostenedione.
Topics: Aldosterone; Androstenedione; Animals; Desipramine; Dose-Response Relationship, Drug; Ear; Female; H | 1989 |
5-Hydroxytryptamine-stimulated inositol phospholipid hydrolysis in the mouse cortex has pharmacological characteristics compatible with mediation via 5-HT2 receptors but this response does not reflect altered 5-HT2 function after 5,7-dihydroxytryptamine l
Topics: 5,7-Dihydroxytryptamine; Animals; Antidepressive Agents; Cerebral Cortex; Desipramine; Electroshock; | 1988 |
Effects of desipramine on stimulation-induced contractions of the vas deferens of rats pretreated either chronically with desipramine or acutely with idazoxan.
Topics: Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Desipramine; Dioxanes; Dioxins; Drug In | 1985 |
Modification by desipramine of the effects of alpha-adrenoceptor antagonists on the contractile responses of the trisected rat vas deferens.
Topics: Adrenergic alpha-Antagonists; Animals; Desipramine; Electric Stimulation; In Vitro Techniques; Male; | 1985 |
Reduced peripheral presynaptic adrenoceptor sensitivity following chronic antidepressant treatment in rats.
Topics: Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Clorgyline; Cocaine; Desipramine; | 1985 |
Some pharmacological actions of nisoxetine, a bicyclic inhibitor of noradrenaline uptake.
Topics: Animals; Bradykinin; Carbachol; Desipramine; Fluoxetine; Guinea Pigs; Histamine; In Vitro Techniques | 1985 |
Release of neuropeptide Y (NPY) induced by tyramine in the isolated vas deferens of rat.
Topics: Animals; Desipramine; Guanethidine; Hydroxydopamines; In Vitro Techniques; Male; Muscle Contraction; | 1987 |
Studies on the mode of action of bretylium and guanethidine in post-ganglionic sympathetic nerve fibres.
Topics: Amphetamine; Animals; Autonomic Fibers, Postganglionic; Bretylium Compounds; Bretylium Tosylate; Des | 1988 |
Antidepressant biochemical profile of the novel bicyclic compound Wy-45,030, an ethyl cyclohexanol derivative.
Topics: Animals; Antidepressive Agents, Tricyclic; Biological Assay; Brain; Cyclohexanols; Desipramine; Dopa | 1986 |
Tricyclic antidepressants antagonize prostaglandin (PG) E2-induced contractions of the guinea pig ileum and hypomotility in the mouse.
Topics: Acetylcholine; Amitriptyline; Animals; Desipramine; Dinoprostone; Guinea Pigs; Histamine Antagonists | 1985 |
Painful postcoital testicular retraction linked with desipramine.
Topics: Adult; Coitus; Depressive Disorder; Desipramine; Humans; Male; Muscle Contraction; Pain; Spasm; Test | 1986 |
The actions of several psychoactive agents upon the muscarinic mechanisms in the superior cervical ganglion of the cat.
Topics: Alkynes; Animals; Atropine; Carbamates; Cats; Desipramine; Dimethylphenylpiperazinium Iodide; Electr | 1974 |
Role of endogenous catecholamines in the anti-inflammatory activity of alpha-adrenoceptor blocking agents.
Topics: Adrenal Glands; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Anti-Inflammator | 1974 |
Pharmacological investigations with benzoctamine (Tacitin), a new psycho-active agent.
Topics: Adjuvants, Anesthesia; Aggression; Animals; Anthracenes; Cats; Central Nervous System; Chlordiazepox | 1973 |
Differentiation between intrinsic and extrinsic acetylcholine receptors of the chick biventer cervicis muscle.
Topics: Acetylcholine; Animals; Bungarotoxins; Chickens; Cholinesterase Inhibitors; Desipramine; Echothiopha | 1974 |
Demethylimipramine (desipramine), an alpha-adrenergic blocking agent.
Topics: Angiotensin II; Animals; Aorta; Desipramine; Drug Antagonism; Drug Synergism; Muscle Contraction; No | 1967 |
Differences in sensitivity to vasoconstrictor drugs within the wall of the sheep carotid artery.
Topics: Angiotensin II; Animals; Carotid Arteries; Desipramine; Histamine; Hot Temperature; In Vitro Techniq | 1972 |
Interactions of bretylium and drugs that inhibit the neuronal membrane transport of norepinephrine in isolated rabbit atria and aortae.
Topics: Animals; Aorta; Bretylium Compounds; Calcium; Cell Membrane; Cocaine; Desipramine; Drug Antagonism; | 1972 |
Effects of desipramine and imipramine on the nerve, muscle and synaptic transmission of rat diaphragms.
Topics: Acetylcholine; Action Potentials; Animals; Axons; Chlorpromazine; Desipramine; Diaphragm; Electric S | 1972 |
Effect of desipramine on the depolarized isolated renal artery.
Topics: Animals; Calcium; Chlorpromazine; Cocaine; Desipramine; Electrophysiology; Muscle Contraction; Pheno | 1967 |
An adrenergic neuron blocking action of propranolol in isolated tissues.
Topics: Amphetamine; Animals; Arteries; Desipramine; Ear; Guanethidine; Ileum; In Vitro Techniques; Lidocain | 1968 |
Some aspects of the adrenergic system of the isolated rat seminal vesicle.
Topics: Animals; Cocaine; Desipramine; Drug Synergism; Electric Stimulation; Epinephrine; Ethanolamines; Gua | 1971 |
Influence of cocaine and desipramine on the contractile response of isolated rabbit pulmonary arteries and aortae to transmural stimulation.
Topics: Animals; Aorta; Calcium; Cocaine; Desipramine; Electric Stimulation; Female; Hydrazines; In Vitro Te | 1971 |
Effect of dimethyl and monomethyl tricyclic antidepressants on central 5-hydroxytryptamine processes in the frog.
Topics: Amitriptyline; Animals; Antidepressive Agents; Anura; Brain; Desipramine; Dibenzazepines; Imipramine | 1971 |
3 H-noradrenaline release and mechanical response in the field stimulated mouse vas deferens.
Topics: Adrenergic alpha-Antagonists; Animals; Atropine; Buffers; Desipramine; Dopamine; Electric Stimulatio | 1971 |
Influence of papaverine and nitrite on the responses to norepinephrine of inner and outer smooth muscle of sheep carotid arteries.
Topics: Animals; Calcium; Carotid Arteries; Depression, Chemical; Desipramine; Muscle Contraction; Muscle, S | 1974 |
Proceedings: Drug-induced changes in the sensitivity of the isthmus of rabbit oviduct to noradrenaline.
Topics: Animals; Cocaine; Desipramine; Drug Synergism; Fallopian Tubes; Female; Hydroxydopamines; Muscle Con | 1974 |
The effect of ethacrynic acid on the guinea-pig and rat isolated vas deferens.
Topics: Animals; Atropine; Cocaine; Desipramine; Ethacrynic Acid; Guinea Pigs; Hexamethonium Compounds; In V | 1974 |
Lack of correlation between profiles of transmitter efflux and of muscular contraction in response to nerve stimulation in isolated guinea-pig vas deferens.
Topics: Animals; Depression, Chemical; Desipramine; Electric Stimulation; Guinea Pigs; In Vitro Techniques; | 1973 |
Pharmacological nature of adrenergic innervation in rat aorta.
Topics: Animals; Aorta; Aorta, Thoracic; Autoradiography; Cocaine; Desipramine; Dose-Response Relationship, | 1973 |
Contractile response of rat aorta to norepinephrine and tyramine.
Topics: Amphetamine; Animals; Aorta, Thoracic; Cocaine; Desipramine; Dopamine; Drug Synergism; Electric Stim | 1972 |
The interaction between desmethylimipramine and guanethidine on the rabbit ileum. The importance of the noradrenaline uptake process in the reversal of guanethidine-induced adrenergic neurone blockade.
Topics: Animals; Biological Transport, Active; Cocaine; Desipramine; Dextroamphetamine; Drug Interactions; E | 1972 |
Uptake of nicotine by the sympathetic nerve terminals in the blood vessel.
Topics: Animals; Aorta; Autonomic Fibers, Postganglionic; Blood Vessels; Cocaine; Desipramine; Extracellular | 1972 |
A quantitative study of the anticholinergic action of several tricyclic antidepressants on the rat isolated fundal strip.
Topics: Amitriptyline; Animals; Atropine; Carbachol; Desipramine; Dibenzocycloheptenes; Dimethylamines; Fema | 1972 |
[Effect of thymoleptic agents on the motor function of the bladder (animal experiments and clinical studies)].
Topics: Adult; Aged; Animals; Cats; Desipramine; Enuresis; Female; Humans; Imipramine; Male; Manometry; Midd | 1972 |
Further evidence of central muscle relaxant activity of imipramine, desmethylimipramine and amitriptyline.
Topics: Amitriptyline; Animals; Behavior, Animal; Blood Pressure; Cats; Desipramine; Female; Imipramine; Mal | 1966 |
Kinetic and thermodynamic considerations regarding the inhibition by tricyclic antidepressants of the uptake of tritiated norepinephrine by the adrenergic nerves in rabbit aortic strips.
Topics: Animals; Antidepressive Agents; Aorta; Desipramine; Energy Transfer; Female; Imipramine; Kinetics; M | 1970 |
Factors affecting the contractile responses of the rat vas deferens to cocaine and tetracaine.
Topics: Animals; Cocaine; Desipramine; Electric Stimulation; Glucose; Guanethidine; Hydrogen-Ion Concentrati | 1970 |
Studies on the mechanism of the inhibitory effect of desipramine (DMI) on vascular smooth muscle contraction.
Topics: Animals; Barium; Calcium; Cell Membrane Permeability; Chlorides; Desipramine; Muscle Contraction; Mu | 1970 |
Blockade of the nicotine-induced norepinephrine release by cocaine, phenoxybenzamine and desipramine.
Topics: Action Potentials; Animals; Axons; Bretylium Compounds; Cocaine; Desipramine; Electric Stimulation; | 1970 |
An investigation of the mechanism of potentiation by cocaine of responses to serotonin in sheep umbilical blood vessels.
Topics: Animals; Cocaine; Cyanides; Desipramine; Dinitrophenols; Drug Synergism; Female; In Vitro Techniques | 1970 |
Concentrations of desipramine in the vas deferens and potentiation of noradrenaline response.
Topics: Animals; Cocaine; Denervation; Desipramine; Drug Synergism; Imipramine; In Vitro Techniques; Male; M | 1971 |
Modifications by propranolol of the response of isolated rabbit atria to endogenous and exogenous noradrenaline.
Topics: Animals; Atrial Function; Depression, Chemical; Desipramine; Drug Antagonism; Electric Stimulation; | 1968 |
The influence of desmethylimipramine on the chronotropic response to endogenous and exogenous noradrenaline in the isolated atria.
Topics: Animals; Cocaine; Desipramine; Drug Antagonism; Drug Synergism; Electric Stimulation; Female; Heart; | 1968 |
A new type of drug enhancement: increased maximum response to cumulative noradrenaline in the isolated rat vas deferens.
Topics: Amitriptyline; Animals; Cocaine; Desipramine; Drug Synergism; Imipramine; Male; Muscle Contraction; | 1968 |
On the inability to produce supersensitivity to catecholamines in intestinal smooth muscle.
Topics: Acetylcholine; Animals; Cocaine; Desipramine; Drug Hypersensitivity; Female; Guinea Pigs; In Vitro T | 1969 |
Some observations on the adrenergic blocking activity of desipramine and amitriptyline on aortic strips of rabbits.
Topics: Amitriptyline; Animals; Aorta; Calcium; Chlorpromazine; Desipramine; In Vitro Techniques; Male; Musc | 1969 |
Desipramine toxicity and its treatment.
Topics: Animals; Blood Pressure; Desipramine; Dogs; Electrocardiography; Epinephrine; Heart; Muscle Contract | 1969 |