desipramine has been researched along with Irritable Bowel Syndrome in 3 studies
Desipramine: A tricyclic dibenzazepine compound that potentiates neurotransmission. Desipramine selectively blocks reuptake of norepinephrine from the neural synapse, and also appears to impair serotonin transport. This compound also possesses minor anticholinergic activity, through its affinity to muscarinic receptors.
desipramine : A dibenzoazepine consisting of 10,11-dihydro-5H-dibenzo[b,f]azepine substituted on nitrogen with a 3-(methylamino)propyl group.
Irritable Bowel Syndrome: A disorder with chronic or recurrent colonic symptoms without a clearcut etiology. This condition is characterized by chronic or recurrent ABDOMINAL PAIN, bloating, MUCUS in FECES, and an erratic disturbance of DEFECATION.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kim, SE | 1 |
| Kubomoto, S | 1 |
| Chua, K | 1 |
| Amichai, MM | 1 |
| Pimentel, M | 1 |
| Cash, BD | 1 |
| Chey, WD | 1 |
| Mayer, EA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Confocal Endomicroscopy Utility for Diagnosing Mucosa Micro-inflammation in Patients With Irritable Bowel Syndrome[NCT02651532] | 74 participants (Actual) | Observational | 2016-01-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for desipramine and Irritable Bowel Syndrome
| Article | Year |
|---|---|
Advances in the management of irritable bowel syndrome.
Topics: Antidepressive Agents, Tricyclic; Carbolines; Cost of Illness; Desipramine; Evidence-Based Medicine; | 2003 |
Clinical practice. Irritable bowel syndrome.
Topics: Adult; Antidepressive Agents, Tricyclic; Carbolines; Cognitive Behavioral Therapy; Desipramine; Fema | 2008 |
1 other study available for desipramine and Irritable Bowel Syndrome
| Article | Year |
|---|---|
"Pre-cebo": an unrecognized issue in the interpretation of adequate relief during irritable bowel syndrome drug trials.
Topics: Adult; Carbolines; Desipramine; Diarrhea; Female; Gastrointestinal Agents; Humans; Irritable Bowel S | 2012 |