desipramine has been researched along with Hyperthyroidism in 6 studies
Desipramine: A tricyclic dibenzazepine compound that potentiates neurotransmission. Desipramine selectively blocks reuptake of norepinephrine from the neural synapse, and also appears to impair serotonin transport. This compound also possesses minor anticholinergic activity, through its affinity to muscarinic receptors.
desipramine : A dibenzoazepine consisting of 10,11-dihydro-5H-dibenzo[b,f]azepine substituted on nitrogen with a 3-(methylamino)propyl group.
Hyperthyroidism: Hypersecretion of THYROID HORMONES from the THYROID GLAND. Elevated levels of thyroid hormones increase BASAL METABOLIC RATE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "05) decrease in brain uptake of both labeled T3 (T3) and labeled thyroxine (T4) across the spectrum of thyroid states from hypothyroid (HYPO) to euthyroid to T4-induced hyperthyroid." | 7.69 | An acute dose of desmethylimipramine inhibits brain uptake of [125I]3,3',5-triiodothyronine (T3) in thyroxine-induced but not T3-induced hyperthyroid rats: implications for tricyclic antidepressant therapy. ( Dratman, MB; Gordon, JT; Greenberg, J; Tomlinson, EE, 1994) |
| "05) decrease in brain uptake of both labeled T3 (T3) and labeled thyroxine (T4) across the spectrum of thyroid states from hypothyroid (HYPO) to euthyroid to T4-induced hyperthyroid." | 3.69 | An acute dose of desmethylimipramine inhibits brain uptake of [125I]3,3',5-triiodothyronine (T3) in thyroxine-induced but not T3-induced hyperthyroid rats: implications for tricyclic antidepressant therapy. ( Dratman, MB; Gordon, JT; Greenberg, J; Tomlinson, EE, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (66.67) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| PRANGE, AJ | 3 |
| LIPTON, MA | 1 |
| LOVE, GN | 1 |
| Gordon, JT | 2 |
| Tomlinson, EE | 2 |
| Greenberg, J | 2 |
| Dratman, MB | 2 |
| Martens, DA | 1 |
| Mason, GA | 1 |
| Bondy, SC | 1 |
| Nemeroff, CB | 1 |
| Walker, CH | 1 |
| Grassby, PF | 1 |
| McNeill, JH | 1 |
1 review available for desipramine and Hyperthyroidism
| Article | Year |
|---|---|
Psychotropic drugs and the thyroid axis: a review of interactions.
Topics: Animals; Body Temperature; Brain; Chlorpromazine; Depressive Disorder; Desipramine; Drug Interaction | 1985 |
5 other studies available for desipramine and Hyperthyroidism
| Article | Year |
|---|---|
EFFECT OF ALTERED THYROID STATUS ON DESMETHYLIMIPRAMINE MORTALITY IN MICE.
Topics: Desipramine; Hyperthyroidism; Imipramine; Mice; Propylthiouracil; Research; Toxicology | 1964 |
An acute dose of desmethylimipramine inhibits brain uptake of [125I]3,3',5-triiodothyronine (T3) in thyroxine-induced but not T3-induced hyperthyroid rats: implications for tricyclic antidepressant therapy.
Topics: Analysis of Variance; Animals; Antidepressive Agents, Tricyclic; Brain; Desipramine; Dose-Response R | 1994 |
Desmethylimipramine, a potent inhibitor of synaptosomal norepinephrine uptake, has diverse effects on thyroid hormone processing in rat brain. I. Effects on in vivo uptake of 125I-labeled thyroid hormones in rat brain.
Topics: Animals; Brain; Desipramine; Hyperthyroidism; Hypothyroidism; Iodine Radioisotopes; Kinetics; Male; | 1993 |
The effects of thyroid state on beta-adrenergic and serotonergic receptors in rat brain.
Topics: Animals; Brain; Cerebellum; Corpus Striatum; Desipramine; Hippocampus; Hyperthyroidism; Hypothyroidi | 1987 |
Hyperthyroidism induces supersensitivity to biogenic amines in rat vascular tissue via a pre- and a postjunctional mechanism.
Topics: Animals; Biogenic Amines; Desipramine; Hydrocortisone; Hyperthyroidism; In Vitro Techniques; Male; M | 1988 |