desipramine has been researched along with Genetic Predisposition in 5 studies
Desipramine: A tricyclic dibenzazepine compound that potentiates neurotransmission. Desipramine selectively blocks reuptake of norepinephrine from the neural synapse, and also appears to impair serotonin transport. This compound also possesses minor anticholinergic activity, through its affinity to muscarinic receptors.
desipramine : A dibenzoazepine consisting of 10,11-dihydro-5H-dibenzo[b,f]azepine substituted on nitrogen with a 3-(methylamino)propyl group.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (80.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Vollbrecht, PJ | 1 |
| Nesbitt, KM | 1 |
| Mabrouk, OS | 1 |
| Chadderdon, AM | 1 |
| Jutkiewicz, EM | 1 |
| Kennedy, RT | 1 |
| Ferrario, CR | 1 |
| Alcaro, A | 1 |
| Cabib, S | 1 |
| Ventura, R | 1 |
| Puglisi-Allegra, S | 1 |
| Licinio, J | 2 |
| O'Kirwan, F | 1 |
| Irizarry, K | 1 |
| Merriman, B | 1 |
| Thakur, S | 1 |
| Jepson, R | 1 |
| Lake, S | 1 |
| Tantisira, KG | 1 |
| Weiss, ST | 1 |
| Wong, ML | 2 |
| Whelan, F | 1 |
| Deloukas, P | 1 |
| Whittaker, P | 1 |
| Delgado, M | 1 |
| Cantor, RM | 1 |
| McCann, SM | 1 |
| Faraone, SV | 1 |
| Biederman, J | 1 |
| Spencer, T | 1 |
| Wilens, T | 1 |
| Seidman, LJ | 1 |
| Mick, E | 1 |
| Doyle, AE | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| [NCT00265291] | Phase 2 | 700 participants (Actual) | Interventional | 1999-11-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for desipramine and Genetic Predisposition
| Article | Year |
|---|---|
Attention-deficit/hyperactivity disorder in adults: an overview.
Topics: Adult; Age Factors; Antidepressive Agents, Tricyclic; Attention Deficit Disorder with Hyperactivity; | 2000 |
2 trials available for desipramine and Genetic Predisposition
| Article | Year |
|---|---|
Association of a corticotropin-releasing hormone receptor 1 haplotype and antidepressant treatment response in Mexican-Americans.
Topics: Adult; Antidepressive Agents; Anxiety; Depressive Disorder; Desipramine; Double-Blind Method; Female | 2004 |
Phosphodiesterase genes are associated with susceptibility to major depression and antidepressant treatment response.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Adult; Aged; Antidepressive Agents; Cyclic Nucleotide Phosphodi | 2006 |
2 other studies available for desipramine and Genetic Predisposition
| Article | Year |
|---|---|
Cocaine and desipramine elicit distinct striatal noradrenergic and behavioral responses in selectively bred obesity-resistant and obesity-prone rats.
Topics: Animals; Body Temperature; Central Nervous System Agents; Cocaine; Corpus Striatum; Desipramine; Dop | 2018 |
Genotype- and experience-dependent susceptibility to depressive-like responses in the forced-swimming test.
Topics: Adrenergic Uptake Inhibitors; Amphetamine; Analysis of Variance; Animals; Antidepressive Agents, Tri | 2002 |