desipramine has been researched along with Generalized Vulvodynia in 2 studies
Desipramine: A tricyclic dibenzazepine compound that potentiates neurotransmission. Desipramine selectively blocks reuptake of norepinephrine from the neural synapse, and also appears to impair serotonin transport. This compound also possesses minor anticholinergic activity, through its affinity to muscarinic receptors.
desipramine : A dibenzoazepine consisting of 10,11-dihydro-5H-dibenzo[b,f]azepine substituted on nitrogen with a 3-(methylamino)propyl group.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pérez-López, FR | 1 |
| Bueno-Notivol, J | 1 |
| Hernandez, AV | 1 |
| Vieira-Baptista, P | 1 |
| Preti, M | 1 |
| Bornstein, J | 1 |
| Foster, DC | 1 |
| Kotok, MB | 1 |
| Huang, LS | 1 |
| Watts, A | 1 |
| Oakes, D | 1 |
| Howard, FM | 1 |
| Poleshuck, EL | 1 |
| Stodgell, CJ | 1 |
| Dworkin, RH | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Vulvar Vestibulitis Trial: Desipramine-Lidocaine[NCT00276068] | 128 participants (Anticipated) | Interventional | 2002-08-31 | Completed | |||
| Randomized Controlled Trial of Fractional CO2 Laser vs Sham Laser for Women With Provoked Vestibulodynia Who Have Failed Conservative Management[NCT03390049] | 0 participants (Actual) | Interventional | 2018-08-31 | Withdrawn (stopped due to No funding) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for desipramine and Generalized Vulvodynia
| Article | Year |
|---|---|
Systematic review and meta-analysis of the effects of treatment modalities for vestibulodynia in women.
Topics: Administration, Intravaginal; Administration, Oral; Adult; Anesthetics, Local; Desipramine; Dyspareu | 2019 |
1 trial available for desipramine and Generalized Vulvodynia
| Article | Year |
|---|---|
Oral desipramine and topical lidocaine for vulvodynia: a randomized controlled trial.
Topics: Administration, Intravaginal; Administration, Oral; Adult; Anesthetics, Local; Antidepressive Agents | 2010 |
Oral desipramine and topical lidocaine for vulvodynia: a randomized controlled trial.
Topics: Administration, Intravaginal; Administration, Oral; Adult; Anesthetics, Local; Antidepressive Agents | 2010 |
Oral desipramine and topical lidocaine for vulvodynia: a randomized controlled trial.
Topics: Administration, Intravaginal; Administration, Oral; Adult; Anesthetics, Local; Antidepressive Agents | 2010 |
Oral desipramine and topical lidocaine for vulvodynia: a randomized controlled trial.
Topics: Administration, Intravaginal; Administration, Oral; Adult; Anesthetics, Local; Antidepressive Agents | 2010 |