desipramine has been researched along with Enuresis in 19 studies
Desipramine: A tricyclic dibenzazepine compound that potentiates neurotransmission. Desipramine selectively blocks reuptake of norepinephrine from the neural synapse, and also appears to impair serotonin transport. This compound also possesses minor anticholinergic activity, through its affinity to muscarinic receptors.
desipramine : A dibenzoazepine consisting of 10,11-dihydro-5H-dibenzo[b,f]azepine substituted on nitrogen with a 3-(methylamino)propyl group.
Enuresis: Involuntary discharge of URINE after expected age of completed development of urinary control. This can happen during the daytime (DIURNAL ENURESIS) while one is awake or during sleep (NOCTURNAL ENURESIS). Enuresis can be in children or in adults (as persistent primary enuresis and secondary adult-onset enuresis).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Plasma concentrations of imipramine and three of its metabolites were determined in children 6 to 15 years of age who received imipramine for treatment of nocturnal enuresis." | 7.67 | Concentrations of imipramine and its metabolites during enuresis therapy. ( DeVane, CL; Sawyer, WP; Walker, RD; Wilson, JA, 1984) |
| "5 mg/kg), each dosage being given for 2 weeks." | 6.67 | Plasma levels and efficacy of imipramine treatment for enuresis. ( Fritz, GK; Rockney, RM; Yeung, AS, 1994) |
| "Three methods for estimating maintenance dosage requirements of imipramine were compared retrospectively in 146 enuretic patients." | 5.28 | Dosage optimization methods applied to imipramine and desipramine in enuresis treatment. ( Domínguez-Gil, A; Fernández de Gatta, MM; García, MJ; Tamayo, M, 1992) |
| " The results obtained show that the variables which are most associated with the reduction of enuresis are, in decreasing order: the dosage of imipramine administered, the duration of treatment, compliance and the level/dose ratio for the sum of the drug and metabolite levels." | 5.28 | The influence of clinical and pharmacological factors on enuresis treatment with imipramine. ( Domínguez-Gil, A; Fernández de Gatta, MM; Galindo, P; García, MJ; Gutierrez, J; Rey, F; Tamayo, M, 1990) |
| "The serum levels of imipramine (IMI) and its active metabolite desipramine (DMI) were monitored in 90 children with primary nocturnal enuresis." | 3.67 | Monitoring of serum levels of imipramine and desipramine and individualization of dose in enuretic children. ( Acosta, A; de Gatta, MF; Dominguez-Gil, A; García, MJ; Gutierrez, JR; Rey, F, 1984) |
| "Plasma concentrations of imipramine and three of its metabolites were determined in children 6 to 15 years of age who received imipramine for treatment of nocturnal enuresis." | 3.67 | Concentrations of imipramine and its metabolites during enuresis therapy. ( DeVane, CL; Sawyer, WP; Walker, RD; Wilson, JA, 1984) |
| "5 mg/kg), each dosage being given for 2 weeks." | 2.67 | Plasma levels and efficacy of imipramine treatment for enuresis. ( Fritz, GK; Rockney, RM; Yeung, AS, 1994) |
| " The results obtained show that the variables which are most associated with the reduction of enuresis are, in decreasing order: the dosage of imipramine administered, the duration of treatment, compliance and the level/dose ratio for the sum of the drug and metabolite levels." | 1.28 | The influence of clinical and pharmacological factors on enuresis treatment with imipramine. ( Domínguez-Gil, A; Fernández de Gatta, MM; Galindo, P; García, MJ; Gutierrez, J; Rey, F; Tamayo, M, 1990) |
| "The aim of the present study was to characterize the kinetic behavior of imipramine (IMI) and desipramine in enuretic children and to evaluate the performance of different methods for dosage prediction based on individual and/or population data." | 1.28 | Prediction of imipramine serum levels in enuretic children by a Bayesian method: comparison with two other conventional dosing methods. ( Amador, D; Domínguez-Gil Hurlé, A; Fernández de Gatta, MM; García, MJ; Gutiérrez, JR; Rey, F; Tamayo, M, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (84.21) | 18.7374 |
| 1990's | 3 (15.79) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| de Gatta, MF | 1 |
| García, MJ | 4 |
| Acosta, A | 1 |
| Rey, F | 3 |
| Gutierrez, JR | 2 |
| Dominguez-Gil, A | 3 |
| DeVane, CL | 1 |
| Walker, RD | 1 |
| Sawyer, WP | 1 |
| Wilson, JA | 1 |
| Mikkelsen, EJ | 4 |
| Rapoport, JL | 4 |
| Zavadil, A | 1 |
| Nee, L | 1 |
| Gruenau, C | 1 |
| Mendelson, W | 1 |
| Gillin, JC | 1 |
| Potter, WZ | 1 |
| Calil, HM | 1 |
| Sutfin, TA | 1 |
| Zavadil, AP | 3 |
| Jusko, WJ | 1 |
| Rapoport, J | 1 |
| Goodwin, FK | 1 |
| Fritz, GK | 1 |
| Rockney, RM | 1 |
| Yeung, AS | 1 |
| Lake, CR | 1 |
| Kopin, IJ | 1 |
| Tamayo, M | 3 |
| Fernández de Gatta, MM | 3 |
| Galindo, P | 1 |
| Gutierrez, J | 1 |
| Maggi, CA | 1 |
| Borsini, F | 1 |
| Lecci, A | 1 |
| Giuliani, S | 1 |
| Meli, P | 1 |
| Gragnani, L | 1 |
| Meli, A | 1 |
| Amador, D | 1 |
| Domínguez-Gil Hurlé, A | 1 |
| Baumann, FW | 1 |
| Hinman, F | 1 |
| Milner, G | 1 |
| Hills, NF | 1 |
| Liederman, PC | 1 |
| Wasserman, DH | 1 |
| Liederman, VR | 1 |
| Wand, H | 1 |
| Appel, P | 1 |
| Eckel, K | 1 |
| Harrer, G | 1 |
| Ayres, CM | 1 |
6 trials available for desipramine and Enuresis
| Article | Year |
|---|---|
Enuresis: psychopathology, sleep stage, and drug response.
Topics: Adolescent; Antidepressive Agents, Tricyclic; Behavior Therapy; Child; Child Behavior Disorders; Cli | 1980 |
Childhood enuresis. II. Psychopathology, tricyclic concentration in plasma, and antienuretic effect.
Topics: Child; Clinical Trials as Topic; Desipramine; Double-Blind Method; Enuresis; Humans; Imipramine; Mal | 1980 |
Plasma levels and efficacy of imipramine treatment for enuresis.
Topics: Adolescent; Ambulatory Care; Child; Desipramine; Dose-Response Relationship, Drug; Enuresis; Female; | 1994 |
Effect of imipramine on norepinephrine and blood pressure in enuretic boys.
Topics: Blood Pressure; Child; Clinical Trials as Topic; Desipramine; Double-Blind Method; Enuresis; Heart R | 1979 |
A double-blind assessment of antidepressants in the treatment of 212 enuretic patients.
Topics: Clinical Trials as Topic; Desipramine; Enuresis; Epilepsy; Female; Humans; Humidity; Imipramine; Mal | 1968 |
Desipramine in the treatment of enuresis.
Topics: Adolescent; Adult; Child; Clinical Trials as Topic; Desipramine; Enuresis; Female; Humans; Male; Pla | 1969 |
13 other studies available for desipramine and Enuresis
| Article | Year |
|---|---|
Monitoring of serum levels of imipramine and desipramine and individualization of dose in enuretic children.
Topics: Adolescent; Child; Child, Preschool; Desipramine; Drug Administration Schedule; Enuresis; Female; Hu | 1984 |
Concentrations of imipramine and its metabolites during enuresis therapy.
Topics: Adolescent; Child; Desipramine; Enuresis; Female; Humans; Imipramine; Male | 1984 |
Active metabolites of imipramine and desipramine in man.
Topics: Adolescent; Adult; Aged; Biotransformation; Child; Desipramine; Double-Blind Method; Enuresis; Femal | 1982 |
Plasma imipramine and desmethylimipramine concentration and clinical response in childhood enuresis.
Topics: Child; Desipramine; Enuresis; Humans; Imipramine; Male; Placebos; Scopolamine Derivatives | 1978 |
Dosage optimization methods applied to imipramine and desipramine in enuresis treatment.
Topics: Adolescent; Algorithms; Child; Child, Preschool; Desipramine; Drug Administration Schedule; Enuresis | 1992 |
The influence of clinical and pharmacological factors on enuresis treatment with imipramine.
Topics: Adolescent; Age Factors; Body Weight; Child; Child, Preschool; Desipramine; Enuresis; Female; Humans | 1990 |
Effect of acute or chronic administration of imipramine on spinal and supraspinal micturition reflexes in rats.
Topics: Animals; Atropine; Desipramine; Enuresis; Fenclonine; Imipramine; Male; Rats; Receptors, Serotonin; | 1989 |
Prediction of imipramine serum levels in enuretic children by a Bayesian method: comparison with two other conventional dosing methods.
Topics: Adolescent; Bayes Theorem; Child; Child, Preschool; Desipramine; Enuresis; Female; Humans; Imipramin | 1989 |
Treatment of incontinent boys with non-obstructive disease.
Topics: Anti-Infective Agents, Urinary; Behavior Therapy; Child; Desipramine; Encopresis; Enema; Enuresis; H | 1974 |
[Effect of thymoleptic agents on the motor function of the bladder (animal experiments and clinical studies)].
Topics: Adult; Aged; Animals; Cats; Desipramine; Enuresis; Female; Humans; Imipramine; Male; Manometry; Midd | 1972 |
[Changes in tonus of the bladder and its sphincter under thymoleptic treatment. Cystomanometric measurements in man].
Topics: Adult; Aged; Amitriptyline; Antidepressive Agents; Carbachol; Desipramine; Dibenzazepines; Enuresis; | 1971 |
Tricyclic antidepressants.
Topics: Amitriptyline; Antidepressive Agents; Desipramine; Dibenzazepines; Enuresis; Humans; Imipramine; Nor | 1968 |
Nocturnal enuresis: remission in a patient treated with desipramine and protriptyline.
Topics: Adult; Antidepressive Agents; Depression; Desipramine; Enuresis; Female; Humans | 1966 |