desipramine has been researched along with Drug Overdose in 20 studies
Desipramine: A tricyclic dibenzazepine compound that potentiates neurotransmission. Desipramine selectively blocks reuptake of norepinephrine from the neural synapse, and also appears to impair serotonin transport. This compound also possesses minor anticholinergic activity, through its affinity to muscarinic receptors.
desipramine : A dibenzoazepine consisting of 10,11-dihydro-5H-dibenzo[b,f]azepine substituted on nitrogen with a 3-(methylamino)propyl group.
Drug Overdose: Accidental or deliberate use of a medication or street drug in excess of normal dosage.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pulmonary edema and a clinical picture suggestive of ARDS was noted in an adolescent girl who ingested a large quantity of desipramine." | 4.78 | Pulmonary complications following tricyclic antidepressant overdose in an adolescent. ( Conway, EE; Zuckerman, GB, 1993) |
| "Sertraline was without effect on vital signs or electrocardiogram, and had no clinically relevant effects on laboratory values." | 2.38 | Toleration and safety of sertraline: experience worldwide. ( Doogan, DP, 1991) |
| " Mechanisms of desipramine toxicity and its dosage recommendations are discussed." | 1.32 | Excess fatality from desipramine and dosage recommendations. ( Amitai, Y; Frischer, H, 2004) |
| "Amitriptyline was studied in greater detail and caused a dose-related (0." | 1.30 | Acute lung failure induced by tricyclic antidepressants. ( Blomgren, B; Dahlin, KL; Lâstbom, L; Ryrfeldt, A, 1997) |
| "Paroxetine (Paxil) is a selective serotonin reuptake inhibitor, one of a new class of antidepressants used in the treatment of obsessive-compulsive disorder, panic disorder, and depression." | 1.30 | Distribution of paroxetine in three postmortem cases. ( Vermeulen, T, 1998) |
| "Nortriptyline was not detected in most cases, suggesting that it may degrade more rapidly than desipramine." | 1.29 | The study of tricyclic antidepressants in formalin-fixed human liver and formalin solutions. ( Wahba, WW; Winek, CL; Zaveri, NR, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (5.00) | 18.7374 |
| 1990's | 13 (65.00) | 18.2507 |
| 2000's | 4 (20.00) | 29.6817 |
| 2010's | 2 (10.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| O'Sullivan, JC | 1 |
| Johnson, AD | 1 |
| Waterman, MA | 1 |
| Varrone, J | 1 |
| Lavoie, K | 1 |
| Manthous, CA | 1 |
| Pierog, JE | 1 |
| Kane, KE | 1 |
| Kane, BG | 1 |
| Donovan, JW | 1 |
| Helmick, T | 1 |
| Amitai, Y | 1 |
| Frischer, H | 1 |
| Kinoshita, H | 1 |
| Taniguchi, T | 1 |
| Kubota, A | 1 |
| Nishiguchi, M | 1 |
| Ouchi, H | 1 |
| Minami, T | 1 |
| Utsumi, T | 1 |
| Motomura, H | 1 |
| Nagasaki, Y | 1 |
| Ameno, K | 1 |
| Hishida, S | 1 |
| Akhtar, M | 1 |
| Goldschlager, NF | 1 |
| Wiley, JF | 1 |
| Winek, CL | 1 |
| Zaveri, NR | 1 |
| Wahba, WW | 1 |
| Zuckerman, GB | 1 |
| Conway, EE | 1 |
| Goodwin, DA | 1 |
| Lally, KP | 1 |
| Null, DM | 1 |
| Appelbaum, PS | 1 |
| Lin, G | 1 |
| Pentel, PR | 1 |
| Shelver, WL | 1 |
| Keyler, DE | 1 |
| Ross, CA | 1 |
| Hieda, Y | 1 |
| Flickinger, MC | 1 |
| Pennell, CA | 1 |
| Murtaugh, MP | 1 |
| Dahlin, KL | 1 |
| Lâstbom, L | 1 |
| Blomgren, B | 1 |
| Ryrfeldt, A | 1 |
| Wilens, TE | 1 |
| Spencer, TJ | 1 |
| Biederman, J | 1 |
| Vermeulen, T | 1 |
| Probst, BD | 1 |
| Cetta, F | 1 |
| Peters, RW | 1 |
| Buser, GA | 1 |
| Kim, HJ | 1 |
| Gold, MR | 1 |
| Doogan, DP | 1 |
| Chahine, RA | 1 |
| Castellanos, A | 1 |
2 reviews available for desipramine and Drug Overdose
| Article | Year |
|---|---|
Pulmonary complications following tricyclic antidepressant overdose in an adolescent.
Topics: Adolescent; Desipramine; Drug Overdose; Female; Humans; Positive-Pressure Respiration; Pulmonary Ede | 1993 |
Toleration and safety of sertraline: experience worldwide.
Topics: 1-Naphthylamine; Amitriptyline; Antidepressive Agents; Depressive Disorder; Desipramine; Drug Overdo | 1991 |
18 other studies available for desipramine and Drug Overdose
| Article | Year |
|---|---|
Comparative resuscitation measures for the treatment of desipramine overdose.
Topics: Adrenergic Agonists; Advanced Cardiac Life Support; Animals; Antidepressive Agents, Tricyclic; Antid | 2014 |
Tardive tachypnea.
Topics: Antidepressive Agents, Tricyclic; Desipramine; Drug Overdose; Female; Humans; Intubation, Intratrach | 2016 |
Tricyclic antidepressant toxicity treated with massive sodium bicarbonate.
Topics: Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Cyclohexanols; Desipramine; Drug Overdose; E | 2009 |
Excess fatality from desipramine and dosage recommendations.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Databases, Factual; Desipramine; Drug Overdose; Hum | 2004 |
An autopsy case of imipramine poisoning.
Topics: Antidepressive Agents, Tricyclic; Autopsy; Cause of Death; Chromatography, High Pressure Liquid; Des | 2005 |
Brugada electrocardiographic pattern due to tricyclic antidepressant overdose.
Topics: Adult; Antidepressive Agents, Tricyclic; Bundle-Branch Block; Clonazepam; Desipramine; Drug Combinat | 2006 |
Electrocardiogram showing changes consistent with desipramine overdose.
Topics: Desipramine; Drug Overdose; Emergencies; Heart; Humans; Phenytoin; Physostigmine | 1994 |
The study of tricyclic antidepressants in formalin-fixed human liver and formalin solutions.
Topics: Amitriptyline; Cryopreservation; Desipramine; Drug Overdose; Drug Stability; Embalming; Evaluation S | 1993 |
Extracorporeal membrane oxygenation support for cardiac dysfunction from tricyclic antidepressant overdose.
Topics: Bradycardia; Desipramine; Drug Overdose; Extracorporeal Membrane Oxygenation; Female; Humans; Infant | 1993 |
Law & psychiatry. Who is responsible when a patient's insurance runs out?
Topics: Adolescent; Cost Control; Depressive Disorder; Desipramine; Drug Overdose; Financing, Personal; Hosp | 1996 |
Bacterial expression and characterization of an anti-desipramine single-chain antibody fragment.
Topics: Amino Acid Sequence; Animals; Antibodies, Anti-Idiotypic; Antidepressive Agents, Tricyclic; Base Seq | 1996 |
Acute lung failure induced by tricyclic antidepressants.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Desipramine; Disease Models, Animal; Dose- | 1997 |
Sudden (un)explained death.
Topics: Antidepressive Agents, Tricyclic; Cause of Death; Child; Depressive Disorder; Desipramine; Drug Over | 1997 |
Distribution of paroxetine in three postmortem cases.
Topics: Adult; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Desipramine; Drug | 1998 |
Patient's discharge linked to end of insurance coverage. Muse v. Charter Hospital of Winston-Salem, Inc.
Topics: Adolescent; Depression; Desipramine; Drug Overdose; Humans; Insurance, Hospitalization; Liability, L | 1995 |
The utility of a 12-lead electrocardiogram in diagnosing a suspected antidepressant overdose.
Topics: Adolescent; Bicarbonates; Desipramine; Drug Overdose; Electrocardiography; Emergency Service, Hospit | 1992 |
Tricyclic overdose causing sustained monomorphic ventricular tachycardia.
Topics: Adult; Desipramine; Drug Overdose; Electrocardiography; Humans; Male; Tachycardia, Ventricular | 1992 |
Myocardial toxicity produced by desipramine overdosage.
Topics: Adult; Arrhythmias, Cardiac; Desipramine; Drug Overdose; Female; Heart; Humans; Suicide, Attempted | 1971 |