desipramine has been researched along with Drug Hypersensitivity in 9 studies
Desipramine: A tricyclic dibenzazepine compound that potentiates neurotransmission. Desipramine selectively blocks reuptake of norepinephrine from the neural synapse, and also appears to impair serotonin transport. This compound also possesses minor anticholinergic activity, through its affinity to muscarinic receptors.
desipramine : A dibenzoazepine consisting of 10,11-dihydro-5H-dibenzo[b,f]azepine substituted on nitrogen with a 3-(methylamino)propyl group.
Drug Hypersensitivity: Immunologically mediated adverse reactions to medicinal substances used legally or illegally.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We present two cases of myocarditis and hepatitis with histologic characteristics of hypersensitivity-mediated drug reactions associated with imipramine and its metabolite, desipramine." | 7.67 | Hypersensitivity myocarditis and hepatitis associated with imipramine and its metabolite, desipramine. ( Bonadies, J; Hardin, NJ; Morrow, PL, 1989) |
| "We present two cases of myocarditis and hepatitis with histologic characteristics of hypersensitivity-mediated drug reactions associated with imipramine and its metabolite, desipramine." | 3.67 | Hypersensitivity myocarditis and hepatitis associated with imipramine and its metabolite, desipramine. ( Bonadies, J; Hardin, NJ; Morrow, PL, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| KRAKOWSKI, AJ | 1 |
| Hamilton, JD | 1 |
| Jones, DR | 1 |
| Maloney, TR | 1 |
| Morrow, PL | 1 |
| Hardin, NJ | 1 |
| Bonadies, J | 1 |
| Panuska, JR | 1 |
| King, TR | 1 |
| Korenblat, PE | 1 |
| Wedner, HJ | 1 |
| Hollander, E | 1 |
| Powell, WJ | 1 |
| Koch-Weser, J | 1 |
| Williams, RA | 1 |
| Rom, WN | 1 |
| Benner, EJ | 1 |
| Govier, WC | 1 |
| Sugrue, MF | 1 |
| Shore, PA | 1 |
9 other studies available for desipramine and Drug Hypersensitivity
| Article | Year |
|---|---|
TREATMENT OF SEVERE DEPRESSION WITH DESIPRAMINE: LONG-TERM TRIAL AND FOLLOW-UP.
Topics: Constipation; Depression; Depressive Disorder; Depressive Disorder, Major; Desipramine; Drug Hyperse | 1964 |
Cross-reaction to maprotiline.
Topics: Adult; Anthracenes; Cross Reactions; Desipramine; Drug Hypersensitivity; Female; Humans; Maprotiline | 1983 |
Massive eosinophilic reaction to desipramine.
Topics: Desipramine; Drug Hypersensitivity; Eosinophilia; Humans; Male; Middle Aged; Neutropenia | 1980 |
Hypersensitivity myocarditis and hepatitis associated with imipramine and its metabolite, desipramine.
Topics: Aged; Chemical and Drug Induced Liver Injury; Desipramine; Drug Hypersensitivity; Female; Humans; Im | 1989 |
Hypersensitivity reaction to desipramine.
Topics: Desipramine; Drug Hypersensitivity; Humans; Male; Middle Aged; Passive Cutaneous Anaphylaxis; Precip | 1987 |
Nontartrazine allergy with desipramine.
Topics: Adult; Azo Compounds; Capsules; Desipramine; Drug Hypersensitivity; Humans; Male; Tablets; Tartrazin | 1987 |
Lethal hepatic necrosis after therapy with imipramine and desipramine.
Topics: Aged; Chemical and Drug Induced Liver Injury; Dermatitis, Exfoliative; Desipramine; Drug Hypersensit | 1968 |
Toxicity by interaction of tricyclic antidepressant and monoamine oxidase inhibitor.
Topics: Aged; Desipramine; Drug Hypersensitivity; Drug Interactions; Female; Humans; Tranylcypromine | 1972 |
On the inability to produce supersensitivity to catecholamines in intestinal smooth muscle.
Topics: Acetylcholine; Animals; Cocaine; Desipramine; Drug Hypersensitivity; Female; Guinea Pigs; In Vitro T | 1969 |