desipramine has been researched along with Diarrhea in 4 studies
Desipramine: A tricyclic dibenzazepine compound that potentiates neurotransmission. Desipramine selectively blocks reuptake of norepinephrine from the neural synapse, and also appears to impair serotonin transport. This compound also possesses minor anticholinergic activity, through its affinity to muscarinic receptors.
desipramine : A dibenzoazepine consisting of 10,11-dihydro-5H-dibenzo[b,f]azepine substituted on nitrogen with a 3-(methylamino)propyl group.
Diarrhea: An increased liquidity or decreased consistency of FECES, such as running stool. Fecal consistency is related to the ratio of water-holding capacity of insoluble solids to total water, rather than the amount of water present. Diarrhea is not hyperdefecation or increased fecal weight.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The aim of this study was to assess the clinical efficacy and safety of cognitive-behavioral therapy (CBT) against education (EDU) and desipramine (DES) against placebo (PLA) in female patients with moderate to severe FBD (irritable bowel syndrome, functional abdominal pain, painful constipation, and unspecified FBD)." | 5.10 | Cognitive-behavioral therapy versus education and desipramine versus placebo for moderate to severe functional bowel disorders. ( Akman, D; Bangdiwala, SI; Blackman, CJ; Bradshaw, B; Dalton, CB; Diamant, NE; Drossman, DA; Duncan, S; Emmott, S; Frusciante, K; Hu, Y; Jia, H; Koch, GG; Le, T; Li, JZ; Meyer, K; Mikula, K; Morris, CB; Proffitt, V; Toner, BB; Whitehead, WE, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kim, SE | 1 |
| Kubomoto, S | 1 |
| Chua, K | 1 |
| Amichai, MM | 1 |
| Pimentel, M | 1 |
| Drossman, DA | 1 |
| Toner, BB | 1 |
| Whitehead, WE | 1 |
| Diamant, NE | 1 |
| Dalton, CB | 1 |
| Duncan, S | 1 |
| Emmott, S | 1 |
| Proffitt, V | 1 |
| Akman, D | 1 |
| Frusciante, K | 1 |
| Le, T | 1 |
| Meyer, K | 1 |
| Bradshaw, B | 1 |
| Mikula, K | 1 |
| Morris, CB | 1 |
| Blackman, CJ | 1 |
| Hu, Y | 1 |
| Jia, H | 1 |
| Li, JZ | 1 |
| Koch, GG | 1 |
| Bangdiwala, SI | 1 |
| Lapin, IP | 1 |
| Osipova, SV | 1 |
| Uskova, NV | 1 |
| Stabrovski, EM | 1 |
1 trial available for desipramine and Diarrhea
| Article | Year |
|---|---|
Cognitive-behavioral therapy versus education and desipramine versus placebo for moderate to severe functional bowel disorders.
Topics: Adult; Antidepressive Agents, Tricyclic; Cognitive Behavioral Therapy; Colonic Diseases, Functional; | 2003 |
3 other studies available for desipramine and Diarrhea
| Article | Year |
|---|---|
"Pre-cebo": an unrecognized issue in the interpretation of adequate relief during irritable bowel syndrome drug trials.
Topics: Adult; Carbolines; Desipramine; Diarrhea; Female; Gastrointestinal Agents; Humans; Irritable Bowel S | 2012 |
SAMe for depression.
Topics: Administration, Oral; Antidepressive Agents; Antidepressive Agents, Tricyclic; Anxiety; Clinical Tri | 1999 |
Pharmacological effects of imipramine and desmethylimipramine in developing rats.
Topics: Age Factors; Animals; Animals, Newborn; Blepharoptosis; Brain Chemistry; Chlorpromazine; Desipramine | 1969 |