Page last updated: 2024-10-25

desipramine and Diarrhea

desipramine has been researched along with Diarrhea in 4 studies

Desipramine: A tricyclic dibenzazepine compound that potentiates neurotransmission. Desipramine selectively blocks reuptake of norepinephrine from the neural synapse, and also appears to impair serotonin transport. This compound also possesses minor anticholinergic activity, through its affinity to muscarinic receptors.
desipramine : A dibenzoazepine consisting of 10,11-dihydro-5H-dibenzo[b,f]azepine substituted on nitrogen with a 3-(methylamino)propyl group.

Diarrhea: An increased liquidity or decreased consistency of FECES, such as running stool. Fecal consistency is related to the ratio of water-holding capacity of insoluble solids to total water, rather than the amount of water present. Diarrhea is not hyperdefecation or increased fecal weight.

Research Excerpts

ExcerptRelevanceReference
" The aim of this study was to assess the clinical efficacy and safety of cognitive-behavioral therapy (CBT) against education (EDU) and desipramine (DES) against placebo (PLA) in female patients with moderate to severe FBD (irritable bowel syndrome, functional abdominal pain, painful constipation, and unspecified FBD)."5.10Cognitive-behavioral therapy versus education and desipramine versus placebo for moderate to severe functional bowel disorders. ( Akman, D; Bangdiwala, SI; Blackman, CJ; Bradshaw, B; Dalton, CB; Diamant, NE; Drossman, DA; Duncan, S; Emmott, S; Frusciante, K; Hu, Y; Jia, H; Koch, GG; Le, T; Li, JZ; Meyer, K; Mikula, K; Morris, CB; Proffitt, V; Toner, BB; Whitehead, WE, 2003)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19901 (25.00)18.7374
1990's1 (25.00)18.2507
2000's1 (25.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kim, SE1
Kubomoto, S1
Chua, K1
Amichai, MM1
Pimentel, M1
Drossman, DA1
Toner, BB1
Whitehead, WE1
Diamant, NE1
Dalton, CB1
Duncan, S1
Emmott, S1
Proffitt, V1
Akman, D1
Frusciante, K1
Le, T1
Meyer, K1
Bradshaw, B1
Mikula, K1
Morris, CB1
Blackman, CJ1
Hu, Y1
Jia, H1
Li, JZ1
Koch, GG1
Bangdiwala, SI1
Lapin, IP1
Osipova, SV1
Uskova, NV1
Stabrovski, EM1

Trials

1 trial available for desipramine and Diarrhea

ArticleYear
Cognitive-behavioral therapy versus education and desipramine versus placebo for moderate to severe functional bowel disorders.
    Gastroenterology, 2003, Volume: 125, Issue:1

    Topics: Adult; Antidepressive Agents, Tricyclic; Cognitive Behavioral Therapy; Colonic Diseases, Functional;

2003

Other Studies

3 other studies available for desipramine and Diarrhea

ArticleYear
"Pre-cebo": an unrecognized issue in the interpretation of adequate relief during irritable bowel syndrome drug trials.
    Journal of clinical gastroenterology, 2012, Volume: 46, Issue:8

    Topics: Adult; Carbolines; Desipramine; Diarrhea; Female; Gastrointestinal Agents; Humans; Irritable Bowel S

2012
SAMe for depression.
    The Medical letter on drugs and therapeutics, 1999, Nov-05, Volume: 41, Issue:1065

    Topics: Administration, Oral; Antidepressive Agents; Antidepressive Agents, Tricyclic; Anxiety; Clinical Tri

1999
Pharmacological effects of imipramine and desmethylimipramine in developing rats.
    Psychopharmacologia, 1969, Volume: 14, Issue:4

    Topics: Age Factors; Animals; Animals, Newborn; Blepharoptosis; Brain Chemistry; Chlorpromazine; Desipramine

1969