desipramine has been researched along with Depression, Endogenous in 568 studies
Desipramine: A tricyclic dibenzazepine compound that potentiates neurotransmission. Desipramine selectively blocks reuptake of norepinephrine from the neural synapse, and also appears to impair serotonin transport. This compound also possesses minor anticholinergic activity, through its affinity to muscarinic receptors.
desipramine : A dibenzoazepine consisting of 10,11-dihydro-5H-dibenzo[b,f]azepine substituted on nitrogen with a 3-(methylamino)propyl group.
| Excerpt | Relevance | Reference |
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| "In the present study, we assessed the relationship between serum folate, vitamin B12, and homocysteine levels and clinical response in patients with major depressive disorder (MDD) who had previously failed to respond to open treatment with fluoxetine 20 mg/day and were enrolled in a 4-week, double-blind trial of either (1) fluoxetine dose increase, (2) lithium augmentation of fluoxetine, or (3) desipramine augmentation of fluoxetine." | 9.11 | Serum folate, vitamin B12, and homocysteine in major depressive disorder, Part 1: predictors of clinical response in fluoxetine-resistant depression. ( Alpert, JE; Bottiglieri, T; Fava, M; Mischoulon, D; Nierenberg, AA; Papakostas, GI; Petersen, T; Rosenbaum, JF; Ryan, JL, 2004) |
| "To evaluate whether serotonin reuptake inhibition is critical to the treatment of obsessive-compulsive disorder, 40 outpatients with a principal diagnosis of obsessive-compulsive disorder were randomized in a double-blind fashion to 8 weeks of treatment with either the serotonin reuptake inhibitor fluvoxamine maleate (n = 21) or the norepinephrine reuptake inhibitor desipramine hydrochloride (n = 19)." | 9.06 | Specificity of serotonin reuptake inhibitors in the treatment of obsessive-compulsive disorder. Comparison of fluvoxamine and desipramine. ( Charney, DS; Delgado, PL; Goodman, WK; Heninger, GR; Krystal, JH; Nagy, LM; Palumbo, J; Price, LH; Rasmussen, SA, 1990) |
| "Doxepin and desipramine at final doses of 188 and 173 mg/day, respectively, were compared in 36 volunteers with major affective or dysthymic disorder and chronic back pain." | 9.05 | Antidepressants in concomitant chronic back pain and depression: doxepin and desipramine compared. ( Benedetti, C; Bokan, JA; Butler, S; Phillips, M; Spengler, D; Ward, N, 1984) |
| "Twenty-six patients with major depressive disorder were treated with desipramine for 4 weeks to determine the effect of the drug on body weight." | 7.67 | The effect of desipramine on body weight in depression. ( Esche, I; Joffe, RT; Levitt, AJ; Sherret, D, 1987) |
| "Sertraline was also associated with a significantly greater number of patients who achieved a "robust" improvement in OCD symptoms (> or =40% reduction) compared with desipramine." | 6.69 | Multicenter double-blind comparison of sertraline and desipramine for concurrent obsessive-compulsive and major depressive disorders. ( Black, DW; Chapman, D; Clary, C; Greist, JH; Harrison, W; Hoehn-Saric, R; Lydiard, B; McElroy, S; Ninan, P; Stahl, S; Zajecka, J, 2000) |
| "Sertraline was better tolerated, resulting in greater patient acceptance." | 6.68 | Sertraline versus desipramine in the treatment of premenstrual syndrome: an open-label trial. ( Freeman, EW; Rickels, K; Sondheimer, SJ; Wittmaack, FM, 1996) |
| "Nefazodone is a new antidepressant exhibiting properties of selective serotonin reuptake inhibition and serotonin-2 receptor antagonism." | 5.29 | Probable nefazodone-induced mania in a patient with unreported bipolar disorder. ( Blaisdell, GD; Jermain, DM; Zaphiris, HA, 1996) |
| "in seven male depressed patients with melancholia and five healthy male control subjects." | 5.27 | Patterns of melatonin rhythms in depression. ( Amsterdam, J; Brown, R; Caroff, S; Frazer, A; Kocsis, J; Stokes, P; Sweeney, J; Winokur, A, 1986) |
| " In each patient, tinnitus subsided spontaneously within 2-4 weeks of onset without any specific treatment, even though the daily dosage of imipramine and the plasma tricyclic levels were constant or increased." | 5.27 | Imipramine and tinnitus. ( Greden, JF; Grunhaus, L; Tandon, R, 1987) |
| "In the present study, we assessed the relationship between serum folate, vitamin B12, and homocysteine levels and clinical response in patients with major depressive disorder (MDD) who had previously failed to respond to open treatment with fluoxetine 20 mg/day and were enrolled in a 4-week, double-blind trial of either (1) fluoxetine dose increase, (2) lithium augmentation of fluoxetine, or (3) desipramine augmentation of fluoxetine." | 5.11 | Serum folate, vitamin B12, and homocysteine in major depressive disorder, Part 1: predictors of clinical response in fluoxetine-resistant depression. ( Alpert, JE; Bottiglieri, T; Fava, M; Mischoulon, D; Nierenberg, AA; Papakostas, GI; Petersen, T; Rosenbaum, JF; Ryan, JL, 2004) |
| "The aim of this study was to test the hypothesis that desipramine would be an effective treatment in cocaine abusers with current depressive disorders." | 5.11 | Desipramine treatment of cocaine-dependent patients with depression: a placebo-controlled trial. ( Ma, GJ; McDowell, D; Nunes, EV; Petkova, E; Rothenberg, J; Seracini, AM; Vosburg, SK, 2005) |
| "In an open-label, parallel-group, forced-titration study, 52 outpatients with DSM-IV major depressive disorder and a baseline Montgomery Asberg Depression Rating Scale score > or =20 were randomly assigned to treatment with paroxetine (to 60 mg/day) or desipramine (to 30 mg/day) in a 3-to-1 ratio, respectively." | 5.10 | Inhibition of norepinephrine uptake in patients with major depression treated with paroxetine. ( Gilmor, ML; Nemeroff, CB; Owens, MJ, 2002) |
| "Thirty-seven patients who fulfilled DSM-III-R criteria for Major Depressive Disorder were recruited for a double-blind controlled trial of Desipramine and placebo for 6 weeks." | 5.07 | The impact of social cognitive variables on the initial level of depression and recovery. ( Checkley, S; Green, B; Lam, DH; Power, MJ, 1994) |
| "To determine the efficacy and tolerability of the tricyclic antidepressant desipramine (DMI) in the treatment of DSM-III-R-diagnosed major depressive disorder in adolescents." | 5.07 | Response to desipramine treatment in adolescent depression: a fixed-dose, placebo-controlled trial. ( Boulos, C; Dubois, C; Ferguson, HB; Katic, M; Kutcher, S; Marton, P; Roberts, N; Simeon, J; Szalai, J; Ward, B, 1994) |
| " Three tricyclic antidepressants examined (imipramine, clomipramine and desipramine) did not seem to have the side effect of pathological weight gain in the frequency distribution pattern." | 5.07 | Changes in the frequency distribution pattern of body weight in patients with major depression. ( Kato, T; Murashita, J; Shioiri, T; Takahashi, S; Yamada, N, 1993) |
| "A 6-week randomized, double-blind, placebo controlled trial of desipramine (DMI) in daily doses averaging 4 to 5 mg/kg for the treatment of children and adolescents with attention deficit disorder with hyperactivity (ADDH) was further analyzed." | 5.07 | A double-blind placebo controlled study of desipramine in the treatment of ADD: III. Lack of impact of comorbidity and family history factors on clinical response. ( Baldessarini, RJ; Biederman, J; Faraone, S; Keenan, K; Wright, V, 1993) |
| "The Personality Disorders Examination (PDE) was administered to 71 bulimia nervosa patients at baseline assessment in a study comparing the effectiveness of cognitive-behavioral treatment with desipramine or the combination of both treatments." | 5.07 | Cluster B personality disorder characteristics predict outcome in the treatment of bulimia nervosa. ( Agras, WS; Rossiter, EM; Schneider, JA; Telch, CF, 1993) |
| "The authors conducted a double-blind study evaluating the cortisol response to 75 mg of desipramine (DMI), administered intramuscularly to 20 patients with major depressive disorder (MDD) and 20 age- and sex-matched normal control subjects." | 5.07 | Cortisol response to intramuscular desipramine in patients with major depression and normal control subjects: a replication study. ( Asnis, GM; Sanderson, WC; van Praag, HM, 1992) |
| "Thirty adolescents (ages 15-20) who met DSM-III-R criteria for major depressive disorder completed a double-blind, placebo-controlled, 6-week, fixed-dose (200 mg daily) study of desipramine (DMI)." | 5.07 | Response to desipramine treatment in adolescent major depression. ( Boulos, C; Ferguson, B; Kutcher, S; Marton, P; Roberts, N; Simeon, J, 1991) |
| "Desipramine was given to 34 outpatients aged 20 to 51 years who had primary major depressive disorder but who were otherwise in good health." | 5.07 | 2-Hydroxydesipramine and desipramine plasma levels and electrocardiographic effects in depressed younger adults. ( Cooper, TB; Johnson, MH; Nelson, LD; Ribner, HS; Stern, SL; Suckow, RF, 1991) |
| "To evaluate whether serotonin reuptake inhibition is critical to the treatment of obsessive-compulsive disorder, 40 outpatients with a principal diagnosis of obsessive-compulsive disorder were randomized in a double-blind fashion to 8 weeks of treatment with either the serotonin reuptake inhibitor fluvoxamine maleate (n = 21) or the norepinephrine reuptake inhibitor desipramine hydrochloride (n = 19)." | 5.06 | Specificity of serotonin reuptake inhibitors in the treatment of obsessive-compulsive disorder. Comparison of fluvoxamine and desipramine. ( Charney, DS; Delgado, PL; Goodman, WK; Heninger, GR; Krystal, JH; Nagy, LM; Palumbo, J; Price, LH; Rasmussen, SA, 1990) |
| "Forty patients with a diagnosis of major depressive disorder were entered in a double-blind study to assess comparative clinical response and pharmacologic parameters of fluvoxamine, a highly selective blocker of serotonin reuptake, and desipramine, a noradrenergic agent." | 5.06 | The role of neuropharmacologic selectivity in antidepressant action: fluvoxamine versus desipramine. ( Kupfer, DJ; Nathan, RS; Perel, JM; Pollock, BG, 1990) |
| " The efficacy of fluvoxamine is compared to that of desipramine in a multicenter double blind placebo controlled six-week flexible dose trial of 90 outpatients with major depressive disorder." | 5.06 | A double-blind comparison of fluvoxamine, desipramine and placebo in outpatients with depression. ( Mattes, J; Roth, D; Sheehan, DV; Sheehan, KH, 1990) |
| "In a double-blind clinical trial involving 28 patients with multiple sclerosis and major depressive disorder, 14 patients were randomly assigned to a 5-week trial of desipramine and individual psychotherapy and 14 to placebo plus psychotherapy." | 5.06 | Antidepressant pharmacotherapy of depression associated with multiple sclerosis. ( Schiffer, RB; Wineman, NM, 1990) |
| "Forty-two outpatients with major depressive disorder entered a double-blind, randomized trial of either desipramine or amitriptyline for a minimum of 6 weeks." | 5.06 | Reduced REM latency predicts response to tricyclic medication in depressed outpatients. ( Debus, JR; Feldman-Koffler, F; Giles, DE; Jarrett, RB; Orsulak, PJ; Roffwarg, HP; Rush, AJ; Weissenburger, J, 1989) |
| "Patients with chronic low-back pain and depression were treated double blind with desipramine or doxepin." | 5.06 | Tricyclic antidepressants for chronic low-back pain. Mechanisms of action and predictors of response. ( Ward, NG, 1986) |
| "Fifty-two adult depressed outpatients fulfilling Research Diagnostic Criteria for Definite Major Depressive Disorder were enrolled in a double-blind study comparing the antidepressant effects of alprazolam versus desipramine." | 5.06 | A comparison of the efficacy and safety of alprazolam and desipramine in depressed outpatients. ( Buchanan, RA; Fleming, JA; Gibson, RE; Keller, FD; Remick, RA, 1988) |
| "The antidepressant efficacy of alprazolam (ALP) was tested in a double-blind controlled comparison with desipramine (DMI) and an ALP-DMI combination in outpatients diagnosed with major depressive disorder by Research Diagnostic Criteria (90% met criteria for endogenous subtype)." | 5.06 | Alprazolam: an antidepressant? Alprazolam, desipramine, and an alprazolam-desipramine combination in the treatment of adult depressed outpatients. ( Edwards, JH; Fawcett, J; Jeffriess, H; Kravitz, HM, 1987) |
| "Zimelidine, a specific 5HT uptake inhibitor (final dose 225 mg), and desipramine, mainly a noradrenaline uptake inhibitor (final dose 150 mg), were given in random order to 24 in- and out-patients fulfilling the Research Diagnostic Criteria for Major Depressive Disorder, definite or probable endogenous type, for a 3-week treatment period." | 5.05 | A double-blind comparison of zimelidine and desipramine in endogenous depression. ( Bratfos, O; Bratlid, T; Haug, JO; Lingjaerde, O, 1983) |
| "Doxepin and desipramine at final doses of 188 and 173 mg/day, respectively, were compared in 36 volunteers with major affective or dysthymic disorder and chronic back pain." | 5.05 | Antidepressants in concomitant chronic back pain and depression: doxepin and desipramine compared. ( Benedetti, C; Bokan, JA; Butler, S; Phillips, M; Spengler, D; Ward, N, 1984) |
| "The efficacy of desipramine for mild depression was tested in a double-blind, placebo-controlled study of outpatients with scores below 19 on the Hamilton Rating Scale for Depression (HAM-D)." | 5.05 | Efficacy of desipramine in depressed outpatients. Response according to research diagnosis criteria diagnoses and severity of illness. ( Harrison, WM; Klein, DF; Liebowitz, MR; McGrath, PJ; Quitkin, FM; Stewart, JW, 1983) |
| "The authors examined the effect of combined thioridazine (THI) and desipramine (DMI) for an early antidepressant response in 14 patients with a DSM III diagnosis of major depressive disorder with melancholia." | 5.05 | Combined thioridazine and desipramine: early antidepressant response. ( Bennett, JA; Garver, DL; Hirschowitz, J; Thurman, DN; Zemlan, F, 1984) |
| "Fifty-four patients (34 outpatients, 20 inpatients) fulfilling Research Diagnostic Criteria for Definite Major Depressive Disorder were enrolled in a double-blind study comparing the antidepressant effects of alprazolam versus desipramine." | 5.05 | A comparison of the safety and efficacy of alprazolam and desipramine in moderately severe depression. ( Buchanan, RA; Fleming, JA; Hamilton, P; Keller, FD; Loomer, F; Miles, JE; Remick, RA, 1985) |
| " Among the more important recent discoveries are the efficacy of the tricyclic antidepressants for panic disorder and agoraphobia with panic attacks; the use of the monoamine oxidase inhibitors for the above disorders and for atypical depression and hysteroid dysphoria; the use of propranolol for anxiety disorders and for uncontrollable violent outbursts; the antianxiety and antipanic effects of clonidine; and the usefulness of lithium in treating schizophrenia and schizoaffective disorder and for emotionally unstable character disorders." | 4.76 | Newer uses for older psychotropic medications. ( Liebowitz, MR, 1982) |
| " Here, we investigated the role of aging in the behavioral effects of the antidepressants, desipramine (DMI) (5, 10, and 20 mg/kg) and fluoxetine (FLX) (5, 10, and 20 mg/kg) in young adults (3-5 months), middle-aged (MA, 12-15 months), and senescent (SE, 23-25 months) male rats in the forced-swim test." | 3.83 | Age-related changes in the antidepressant-like effect of desipramine and fluoxetine in the rat forced-swim test. ( Fernández-Guasti, A; Martínez-Mota, L; Olivares-Nazario, M, 2016) |
| " CUS-exposed rats showed depressive-like behavior with reduced weight gain, reduced consumption of sucrose solution, increased immobility in the forced swimming test, and hypolocomotion in an open field." | 3.78 | Effect of long-term caffeine administration on depressive-like behavior in rats exposed to chronic unpredictable stress. ( Alova, LH; Nikolov, RP; Pechlivanova, DM; Petkov, VV; Tchekalarova, JD; Yakimova, KS, 2012) |
| "Developmental deficits in GABAergic inhibition in the forebrain cause behavioral and endocrine abnormalities and selective antidepressant drug responsiveness indicative of anxious-depressive disorders such as melancholic depression, which are frequently characterized by HPA axis hyperactivity and greater efficacy of desipramine versus fluoxetine." | 3.76 | gamma-Aminobutyric acid-type A receptor deficits cause hypothalamic-pituitary-adrenal axis hyperactivity and antidepressant drug sensitivity reminiscent of melancholic forms of depression. ( Andrews, AM; Earnheart, JC; Lal, R; Luellen, BA; Luscher, B; Shen, Q, 2010) |
| "The purpose of this study was to determine the occurrence of leukopenia and other blood dyscrasias associated with psychiatric use of carbamazepine and valproate." | 3.69 | Blood dyscrasias with carbamazepine and valproate: a pharmacoepidemiological study of 2,228 patients at risk. ( Baldessarini, RJ; Castillo, J; Kando, JC; Tohen, M; Zarate, C, 1995) |
| "Thirty-six outpatients aged 20 to 51 with RDC primary major depressive disorder (MDD) completed a 5-week trial of desipramine following a week of single-blind placebo." | 3.69 | 2-Hydroxydesipramine and desipramine plasma levels: how are they related to antidepressant response? ( Cooper, TB; Johnson, MH; Nelson, LD; Stern, SL; Suckow, RF, 1996) |
| "alpha 2-Adrenergic receptor sensitivity was assessed during desipramine treatment by carefully monitoring clonidine-induced blood pressure changes, as well as symptomatology, in three patients with major depressive disorder." | 3.67 | Adrenergic-receptor desensitization and course of clinical improvement with desipramine treatment. ( Garver, DL; Greenblum, DN; Kanter, DR; Mavroidis, ML, 1984) |
| "EEG sleep recordings and two provocative neuroendocrinological tests (the DST and the GH stimulation test after desipramine) were investigated in two depressed pubertal monozygotic twin boys with Major Depressive Disorder and compared with results from one normal pubertal control boy and an adolescent girl suffering from major depression." | 3.67 | Electroencephalogram and neuroendocrine parameters in pubertal and adolescent depressed children. A case report study. ( Hoffmann, G; Kerkhofs, M; Linkowski, P; Mendlewicz, J, 1984) |
| "The use of desipramine in treating major depressive disorder in the hospitalized medically ill patient is described." | 3.67 | Use of desipramine in the medically ill. ( Cavanaugh, SV, 1984) |
| " In the present study, thyroid functions (TFTs) and thyrotropin-releasing hormone (TRH) stimulation of thyroid-stimulating hormone (TSH) were measured before and after treatment with desipramine (DMI) in 13 men with a diagnosis of major depressive disorder." | 3.67 | The thyroid axis and desipramine treatment in depression. ( Anton, RF; Brady, KT, 1989) |
| "Two patients are described who developed testicular swelling and pain during treatment with desipramine." | 3.67 | Desipramine and testicular swelling in two patients. ( Thienhaus, OJ; Vogel, N, 1988) |
| "25 years who met RDC criteria for major depressive disorder as assessed with the K-SADS, were treated for 6 weeks on a fixed schedule of imipramine hydrochloride titrated to a dosage of 5." | 3.67 | Imipramine in adolescent major depression: plasma level and clinical response. ( Ambrosini, P; Cooper, T; Davies, M; Fried, J; King, J; Puig-Antich, J; Rabinovich, H; Ryan, ND; Torres, D, 1986) |
| "Twenty-six patients with major depressive disorder were treated with desipramine for 4 weeks to determine the effect of the drug on body weight." | 3.67 | The effect of desipramine on body weight in depression. ( Esche, I; Joffe, RT; Levitt, AJ; Sherret, D, 1987) |
| " administration of 75 mg of desipramine on growth hormone (GH) secretion was investigated in a sample of 87 patients with major depressive disorders and in 31 normal controls." | 3.67 | Growth hormone release after desipramine in depressive illness. ( Charles, G; Decoster, C; Kerkhofs, M; Meesters, P; Mendlewicz, J; Vanderelst, M, 1985) |
| "Eleven drug free patients meeting Research Diagnostic Criteria for Major Depressive Disorder have been treated with desipramine and given a clonidine infusion after 0, 1 and 3 weeks of treatment." | 3.66 | The effect of desipramine upon central adrenergic function in depressed patients. ( Checkley, SA; Dawling, S; Glass, IB; Shur, E, 1982) |
| "Somatic side effects of antidepressant medications and of depression and anxiety were quantified in depressed patients before and after 4 weeks of treatment with amitriptyline (N = 11), or desipramine (N = 12)." | 3.66 | Somatic symptoms in depression and antidepressants. ( Claghorn, JL; Mathew, RJ; Reck, JJ; Thapar, R; Weinman, ML, 1983) |
| "Monitoring tricyclic antidepressant concentrations in the plasma of 43 patients with major depressive disorders indicated that some responded to imipramine or desipramine but not to amitriptyline or nortriptyline, or vice versa, even though plasma levels were within therapeutic ranges." | 3.66 | The methylphenidate test for differentiating desipramine-responsive from nortriptyline-responsive depression. ( Bagri, S; Fawcett, J; Javaid, JI; Sabelli, HC, 1983) |
| "The effects of imipramine treatment and plasma drug levels were studied in 20 prepubertal children (16 males, 4 females; age range 7-12 years) hospitalized for major depressive disorder (DSM-III criteria)." | 3.66 | Depression in children: relationship between plasma imipramine levels and response. ( Preskorn, SH; Weller, EB; Weller, RA, 1982) |
| " They received desipramine for 6 weeks in order to simulate the length of time and dosing used previously to obtain an IR-1 down-regulation and a therapeutic response in depressed patients." | 2.73 | Platelet imidazoline receptors as state marker of depressive symptomatology. ( Baker, R; Halaris, A; Piletz, J, 2008) |
| "Desipramine or imipramine was added to fluoxetine and Hamilton Rating Scale for Depression (HAM-D) scores, Beck Depression Inventory (BDI) scores, and plasma tricyclic levels were monitored for 3 weeks." | 2.69 | Do depressed subjects who have failed both fluoxetine and a tricyclic antidepressant respond to the combination? ( Joffe, RT; Kamil, R; Levitt, AJ; McIntyre, R, 1999) |
| "Sertraline was significantly more effective than placebo or desipramine; desipramine was not better than placebo (F2,163 = 12." | 2.69 | Differential response to antidepressants in women with premenstrual syndrome/premenstrual dysphoric disorder: a randomized controlled trial. ( Freeman, EW; Polansky, M; Rickels, K; Sondheimer, SJ, 1999) |
| "Sertraline was also associated with a significantly greater number of patients who achieved a "robust" improvement in OCD symptoms (> or =40% reduction) compared with desipramine." | 2.69 | Multicenter double-blind comparison of sertraline and desipramine for concurrent obsessive-compulsive and major depressive disorders. ( Black, DW; Chapman, D; Clary, C; Greist, JH; Harrison, W; Hoehn-Saric, R; Lydiard, B; McElroy, S; Ninan, P; Stahl, S; Zajecka, J, 2000) |
| "4." | 2.68 | REM latency, dexamethasone suppression test, and thyroid releasing hormone stimulation test in posttraumatic stress disorder. ( Chen, CC; Chicz-Demet, A; Demet, EM; Kauffmann, CD; Reist, C, 1995) |
| "Desipramine was an effective antidepressant in this sample and was associated with significantly greater reduction in depressive symptoms than was placebo; however, desipramine treatment was not associated with greater reductions in cocaine use for either the depressed or euthymic subgroup." | 2.68 | Differential symptom reduction in depressed cocaine abusers treated with psychotherapy and pharmacotherapy. ( Carroll, KM; Nich, C; Rounsaville, BJ, 1995) |
| "Tachycardia was the most common change (36%)." | 2.68 | Electrocardiographic changes during desipramine and clomipramine treatment in children and adolescents. ( Allen, AJ; Hamburger, SD; Leonard, HL; Meyer, MC; Rapoport, JL; Richter, D; Swedo, SE; Tucker, E, 1995) |
| "Sertraline was better tolerated, resulting in greater patient acceptance." | 2.68 | Sertraline versus desipramine in the treatment of premenstrual syndrome: an open-label trial. ( Freeman, EW; Rickels, K; Sondheimer, SJ; Wittmaack, FM, 1996) |
| "Desipramine-treated depressed patients were more satisfied and were rated as more improved." | 2.68 | A double-blind, placebo-controlled trial of desipramine for primary alcohol dependence stratified on the presence or absence of major depression. ( Cutler, RB; Kocsis, JH; Mason, BJ; Ritvo, EC, 1996) |
| "Thus, antisocial personality disorder was a poor prognostic factor for treatment retention and continued cocaine abuse, and medication did not improve treatment outcome for the ASP patients, but did for the non-ASP patients." | 2.67 | Antisocial personality disorder as a prognostic factor for pharmacotherapy of cocaine dependence. ( Kosten, T; Leal, J; Ziedonis, D, 1994) |
| " Side effect ratings and EKGs were done weekly." | 2.67 | Side effects of methylphenidate and desipramine alone and in combination in children. ( Biancaniello, TM; Carlson, GA; Kelly, KL; Pataki, CS; Rapport, MD, 1993) |
| "Although patients with a history of substance abuse reported higher levels of anxiety and depression at presentation for treatment than patients without such histories, the two groups reported a similar age of onset of their bulimia nervosa and similar severity of eating pathology with regards to binge and vomit frequencies and measures of concern about body shape and weight." | 2.67 | The impact of prior substance abuse on treatment outcome for bulimia nervosa. ( Pike, KM; Strasser, TJ; Walsh, BT, 1992) |
| "The imipramine dosage was flexible to give a plasma concentration around 200 nmol/l and mianserin was given at a fixed dosage of 30 mg daily." | 2.67 | Combined treatment with imipramine and mianserin. A controlled pilot study. ( Bech, P; Clemmesen, L; Klysner, R; Lauritzen, L; Loldrup, D; Lunde, M; Schaumburg, E; Waarst, S, 1992) |
| "Desipramine-treated subjects showed gradual improvement over the course of the study, and the improvement in week 1 was not so strongly predictive of overall improvement." | 2.67 | Antidepressant or antianxiety? A study of the efficacy of antidepressant medication. ( Edwards, J; Fawcett, J; Fogg, L; Kravitz, HM, 1990) |
| "Moclobemide was compared with desipramine in 30 patients with endogenous depression." | 2.67 | Moclobemide (Ro 11-1163) versus desipramine in the treatment of endogenous depression. ( Gabelic, I; Moll, E, 1990) |
| "Fenfluramine 40-120 mg/day was then added to the ongoing desipramine in a placebo substitution design." | 2.67 | Fenfluramine augmentation in tricyclic-refractory depression. ( Charney, DS; Delgado, PL; Heninger, GR; Price, LH, 1990) |
| "Imipramine was used to treat 18 depressed inpatients for 22 days." | 2.66 | The influence of the route of administration of imipramine on imipramine and desipramine blood levels. ( Albin, H; Demotes-Mainard, F; Fança, X; Rigal, J; Vinçon, G, 1989) |
| " This treatment was combined with either placebo, diazepam (10 mg/day) or dixyrazine (50 mg/day)." | 2.66 | Comparison of the serum levels in primary non-agitated depressed out-patients treated with imipramine in combination with placebo, diazepam or dixyrazine. ( Feet, PO; Holm, V; Larsen, S; Liden, A; Lillevold, PE; Robak, OH, 1987) |
| " Our study indicates that the discontinuation of diazepam, even when given in moderate dosage over a relatively short period of time, may cause withdrawal reactions in combined antidepressant/diazepam treatment." | 2.66 | Withdrawal reactions to diazepam in combined imipramine/diazepam treatment of primary nonagitated depressed outpatients. ( Feet, PO; Larsen, S; Lillevold, PE; Robak, OH, 1988) |
| "Patients with endogenous depression, those with primary depression, and those with abnormal dexamethasone suppression test results yielded similar therapeutic thresholds, while the sharpest blood level/response relationship emerged in the subgroup with an abnormal escape from dexamethasone." | 2.66 | Desipramine plasma levels and clinical response: evidence for a curvilinear relationship. ( Coryell, W; Sherman, A; Turner, RD, 1987) |
| "It was observed that two patients with bipolar depression developed mania during crossover treatment with desipramine, while two patients with bipolar depression who were treated with zimelidine during the second treatment period did not show any symptoms of mania." | 2.65 | Comparison between zimelidine and desipramine in endogenous depression. A cross-over study. ( Aberg-Wistedt, A, 1982) |
| " The mean maintenance dosage of trazodone was 300 mg (range 200-350 mg) and of imipramine 160 mg (range 150-175 mg)." | 2.65 | A double blind comparison of the efficacy and safety of trazodone and imipramine in endogenous depression. ( Al-Yassiri, MM; Ankier, SI; Bridges, PK, 1983) |
| " For example, the long-term administration of SSRIs produces certain effects on serotonergic systems, but not noradrenergic ones." | 2.41 | Norepinephrine involvement in antidepressant action. ( Frazer, A, 2000) |
| " In many instances, a knowledge of the drug metabolism status of a patient can be helpful in the selection of a drug and its dosage regimen, and in the prediction of possible drug/drug interactions when two or more drugs have to be administered concomitantly." | 2.39 | Polymorphism in the metabolism of drugs, including antidepressant drugs: comments on phenotyping. ( Coutts, RT, 1994) |
| "Sertraline was without effect on vital signs or electrocardiogram, and had no clinically relevant effects on laboratory values." | 2.38 | Toleration and safety of sertraline: experience worldwide. ( Doogan, DP, 1991) |
| "Depressive disorder is a common complication of stroke." | 2.38 | Depression and cerebrovascular disease. ( Fedoroff, JP; Morris, PL; Robinson, RG, 1990) |
| " Future studies should control for severity of illness in assessing dose-response relationships." | 2.37 | Relationship of desipramine plasma levels to therapeutic response: a critical reappraisal of the data. ( Friedel, RO, 1984) |
| "It is important to understand both the kinetic and the dynamic implications of dosing TCAs and BZs in the elderly, for whom these drugs are frequently prescribed." | 2.37 | Implications of dosing tricyclic antidepressants and benzodiazepines in geriatrics. ( Cutler, NR; Narang, PK, 1984) |
| "Although depressive disorders affect approximately 5% of the population in developed countries each year, current antidepressants usually require several weeks to produce beneficial clinical effects and are only effective in about 55% of patients." | 1.35 | Early prediction of the effectiveness of antidepressants: inputs from an animal model. ( Friedman, A; Lax, E; Lubin, N; Merenlender, A; Rosenstein, M; Yadid, G, 2009) |
| "Global transient cerebral ischemia was performing with the four-vessels occlusion method." | 1.35 | Behavioral effects of four antidepressants on an ischemic rat model of emotional disturbances. ( Bantsiele, GB; Bentué-Ferrer, D; Bourin, M; Laviolle, B; Reymann, JM; Saïkali, S, 2009) |
| "Desipramine treatment produced significant increases in urinary norepinephrine (NE) and normetanephrine (NMN) and plasma NE at Weeks 4 and 6, but not at Week 1." | 1.35 | Enhanced norepinephrine output during long-term desipramine treatment: a possible role for the extraneuronal monoamine transporter (SLC22A3). ( Alpert, J; Hennen, J; Koutsos, M; McHale, N; Mooney, JJ; Pappalardo, K; Samson, JA; Schildkraut, JJ, 2008) |
| "Treatment with desipramine or imipramine, however, was not effective at reducing immobility in the 21-day-old rats." | 1.35 | Juvenile rats in the forced-swim test model the human response to antidepressant treatment for pediatric depression. ( Bylund, DB; Happe, HK; Petty, F; Reed, AL, 2008) |
| "Desipramine treatment normalized depressive-like behavior and elevated the dopaminergic mesolimbic activity, although not to control levels." | 1.35 | VTA dopamine neuron bursting is altered in an animal model of depression and corrected by desipramine. ( Dremencov, E; Friedman, A; Friedman, Y; Yadid, G, 2008) |
| "Imipramine doses were adjusted to attain a predefined fixed plasma level." | 1.35 | Efficacy of imipramine in psychotic versus nonpsychotic depression. ( Birkenhager, TK; Bruijn, JA; Moleman, P; Mulder, PG; van den Broek, WW, 2008) |
| " Overall, the dose-response and time-of-recovery relationships for altered NET expression matched those for production of antidepressant-like effects on behavior." | 1.35 | Norepinephrine transporter regulation mediates the long-term behavioral effects of the antidepressant desipramine. ( Baros, AM; Bondi, CO; Lapiz, MD; Morilak, DA; O'Donnell, JM; Zhang, HT; Zhao, Z, 2008) |
| " In contrast chronic administration of all three drugs resulted in increased expression of exon V- and exon I-containing transcripts (fluoxetine and TCP only) but no significant changes were recorded for exon III and IV mRNAs." | 1.33 | Biphasic change in BDNF gene expression following antidepressant drug treatment explained by differential transcript regulation. ( Khundakar, AA; Zetterström, TSC, 2006) |
| "After CYP2D6 phenotype determination with dextromethorphan, 31 patients were treated with oral DMI at a dosage of 100 mg per day for 3 weeks." | 1.30 | Relationship between plasma desipramine levels, CYP2D6 phenotype and clinical response to desipramine: a prospective study. ( Avenoso, A; Campo, GM; Caputi, AP; Gitto, C; Perucca, E; Spina, E, 1997) |
| " Preclinical studies have shown that long-term administration of various antidepressants causes down-regulation of brain serotonin 2 (5-HT2) receptors in rodents, but it is unknown if similar changes occur following antidepressant treatment in depressed patients." | 1.30 | Decrease in brain serotonin 2 receptor binding in patients with major depression following desipramine treatment: a positron emission tomography study with fluorine-18-labeled setoperone. ( Adam, MJ; Dennie, J; Lam, RW; Lane, CJ; Liddle, PF; Ruth, TJ; Shiah, IS; Yatham, LN, 1999) |
| "Treatment with desipramine (n = 26) did not alter significantly any of the model parameters and had no effect on circadian variability in any patient group." | 1.29 | Disruption of circadian MHPG rhythmicity in major depression. ( DeMet, E; Gwirtsman, HE; Halaris, A; Piletz, JE, 1994) |
| "In this study, 59 patients with endogenous depression received a fixed dose of desipramine and the steady-state plasma concentration of desipramine and 2-hydroxydesipramine were determined by high-pressure chromatography." | 1.29 | Pharmacogenetics of desipramine metabolism. ( Miescke, KJ; Musa, MN, 1994) |
| "Sertraline treatment decreased apomorphine-induced hypothermia by almost half in FSLs, whereas slight hyperthermia was induced in FRL rats instead." | 1.29 | Effect of chronic antidepressant treatment on responses to apomorphine in selectively bred rat strains. ( Overstreet, DH; Pucilowski, O, 1993) |
| " Addition of fluvoxamine to patients on a stable desipramine dosage regimen resulted in a slight, but statistically not significant, increase in desipramine plasma concentrations." | 1.29 | Fluvoxamine-induced alterations in plasma concentrations of imipramine and desipramine in depressed patients. ( Avenoso, A; Campo, GM; Caputi, AP; Pollicino, AM; Spina, E, 1993) |
| "No significant arrhythmias or tachycardias were observed." | 1.29 | ECG changes in pediatric patients on tricyclic antidepressants, desipramine, and imipramine. ( Giuffre, RM; Johnson, A; O'Malley, K, 1996) |
| "Nefazodone is a new antidepressant exhibiting properties of selective serotonin reuptake inhibition and serotonin-2 receptor antagonism." | 1.29 | Probable nefazodone-induced mania in a patient with unreported bipolar disorder. ( Blaisdell, GD; Jermain, DM; Zaphiris, HA, 1996) |
| "Eight patients with endogenous depression who had received no antidepressant treatment for the previous year were treated with the noradrenaline (NA) uptake inhibitor, desipramine (DMI)." | 1.28 | Noradrenaline uptake inhibition increases melatonin secretion, a measure of noradrenergic neurotransmission, in depressed patients. ( Checkley, SA; Dawling, S; Palazidou, E; Papadopoulos, A; Ratcliff, H, 1992) |
| "Treatment with desipramine for 28 days had no effect on the binding parameters in depressed patients when compared to pretreatment values." | 1.28 | Platelet alpha 2-adrenergic receptors in depressed patients and healthy volunteers: the effects of desipramine. ( Auffarth, SE; Coote, M; Gupta, RN; Steiner, M; Werstiuk, ES, 1992) |
| "There have been additional reports of sudden death in children." | 1.28 | Sudden death in children receiving Norpramin: a review of three reported cases and commentary. ( Cohen, DJ; King, RA; Kleinman, CS; Leckman, JF; Nelson, JC; Rasmusson, A; Riddle, MA, 1991) |
| " Desipramine plasma levels drawn 24 hours after an initial standardized dose were used to rapidly adjust desipramine dosage and compensate for the interactive effects of fluoxetine on desipramine levels in the blood." | 1.28 | A preliminary, open study of the combination of fluoxetine and desipramine for rapid treatment of major depression. ( Bowers, MB; Jatlow, PI; Mazure, CM; Nelson, JC, 1991) |
| "The literature is devoid of reports indicating that a reduction in the dosage or discontinuation of antidepressants of any chemical class produces symptoms of major depression within 2-4 d." | 1.28 | Symptoms of major depression: acute effect of withdrawing antidepressants. ( Del Medico, VJ; Dilsaver, SC; Halle, MH, 1991) |
| "Tranylcypromine was effective in the treatment of 14 patients meeting both the National Institute of Mental Health and DSM-III-R criteria for winter depression." | 1.28 | Pharmacological responsiveness of winter depression. ( Del Medico, VJ; Dilsaver, SC; Jaeckle, S; Quadri, A, 1990) |
| "DSM-III-R melancholia criteria were also associated with poor hospital response but slightly less predictive." | 1.28 | Does melancholia predict response in major depression? ( Jatlow, PI; Mazure, CM; Nelson, JC, 1990) |
| "The drug-drug interactions with fluoxetine, a pure serotonergic reuptake blocker with a unique profile of side effects, have not been studied adequately." | 1.28 | Drug-drug interactions of fluoxetine with tricyclics. ( von Ammon Cavanaugh, S, 1990) |
| " There was no change in alpha MT6s excretion, and thus the previously reported potentiation of the efficacy of tricyclic antidepressants in combination with T3 does not appear to be mediated through an alteration in noradrenergic neurotransmission." | 1.28 | A study of the effects of desipramine treatment alone and in combination with L-triiodothyronine on 6-sulphatoxymelatonin excretion in depressed patients. ( Arendt, J; Bearn, J; Checkley, SA; Franey, C, 1989) |
| "Doxepin has gained favour for use in the geriatric population due to claims of low cardiovascular side effects." | 1.28 | Comparative plasma levels of doxepin and desipramine in the elderly. ( Ancill, RJ; Gosselin, C, 1989) |
| " No adverse reactions were reported, including hypertensive and hyperpyrexic crises." | 1.28 | The safety of switching rapidly from tricyclic antidepressants to monoamine oxidase inhibitors. ( Kahn, D; Opler, LA; Silver, JM, 1989) |
| " This is most likely due to the saturation within therapeutic dosage range of the subspecies of cytochrome P-450 responsible for hydroxylation of DMT." | 1.28 | Nonlinear kinetics of trimipramine in depressed patients. ( Musa, MN, 1989) |
| "Sulpiride isomers were studied in the rat in four behavioural models of depression which are thought to be influenced by neuroleptics in different ways." | 1.27 | Antidepressant versus neuroleptic activities of sulpiride isomers on four animal models of depression. ( Dall'Olio, R; Gaggi, R; Gandolfi, O; Montanaro, N; Vaccheri, A, 1984) |
| "Treatment with lithium carbonate significantly reduced urinary norepinephrine, normetanephrine, 3-methoxy-4-hydroxyphenylglycol, and vanillylmandelic acid output as well as whole-body norepinephrine turnover." | 1.27 | Electroconvulsive treatment and lithium carbonate. Their effects on norepinephrine metabolism in patients with primary, major depressions. ( Karoum, F; Linnoila, M; Potter, WZ; Rosenthal, N, 1983) |
| " When DMI dosage was raised after an initial steady state had been reached, the rise in plasma DMI level was proportionately greater than the increase in dosage, suggesting saturation of DMI elimination pathways." | 1.27 | The nonlinear kinetics of desipramine and 2-hydroxydesipramine in plasma. ( Cooke, RG; Persad, E; Reed, KL; Stancer, HC; Warsh, JJ, 1984) |
| "The optimal treatment for depressive disorders in pregnancy remains controversial." | 1.27 | Electroconvulsive therapy in pregnancy. ( Berger, NG; Repke, JT, 1984) |
| "The effect of chronic administration of desipramine, a relatively specific inhibitor of the reuptake of norepinephrine (NE), on heart rate, blood pressure, and concentrations of NE in plasma was examined in elderly depressed women." | 1.27 | Effects of chronic desipramine on plasma norepinephrine concentrations and cardiovascular parameters in elderly depressed women: a preliminary report. ( Cutler, NR; Linnoila, M; Potter, WZ; Rudorfer, MV; Scheinin, M; Zavadil, AP, 1984) |
| "Treatment with carbamazepine reduced CSF somatostatin (p less than ." | 1.27 | CSF somatostatin in affective illness and normal volunteers. ( Ballenger, JC; Gold, PW; Post, RM; Rubinow, DR, 1985) |
| "These findings support a link between PTSD and affective illness." | 1.27 | Biological markers of affective disorders and posttraumatic stress disorder: a pilot study with desipramine. ( Djenderedjian, A; Haier, RJ; Kauffman, CD; Nelson, JN; Reist, C, 1987) |
| " If comparable dosage is administered, nonlinear increases in DMI levels result in lower OH-DMI/DMI ratios similar to those in younger patients." | 1.27 | Hydroxydesipramine in the elderly. ( Atillasoy, E; Jatlow, PI; Mazure, C; Nelson, JC, 1988) |
| "Desipramine was associated with a much higher frequency of jitteriness than was imipramine." | 1.27 | The jitteriness syndrome in panic disorder patients treated with antidepressants. ( Balon, R; Lycaki, H; Pohl, R; Yeragani, VK, 1988) |
| "1." | 1.27 | Behavioural and neuropharmacological properties of the dibenzazepines, desipramine and lofepramine: studies on the olfactory bulbectomized rat model of depression. ( Leonard, BE; O'Connor, WT, 1988) |
| "We describe the relationship of 2-hydroxydesipramine (OH-DMI) plasma levels and response in a prospective DMI study in which dosage was rapidly adjusted to achieve a relatively uniform DMI plasma level." | 1.27 | Antidepressant activity of 2-hydroxydesipramine. ( Jatlow, PI; Mazure, C; Nelson, JC, 1988) |
| "in seven male depressed patients with melancholia and five healthy male control subjects." | 1.27 | Patterns of melatonin rhythms in depression. ( Amsterdam, J; Brown, R; Caroff, S; Frazer, A; Kocsis, J; Stokes, P; Sweeney, J; Winokur, A, 1986) |
| " Plasma level determinations were measured 24 hours after a single dose of DMI 50 mg, and then at weekly intervals thereafter while receiving once daily bedtime dosing with DMI 150 mg or 200 mg." | 1.27 | Possible nonlinear pharmacokinetics of desipramine after once daily dosing. ( Amsterdam, JD; Brunswick, DJ; Potter, L; Rickels, K, 1986) |
| " Further fixed dosage studies are necessary to confirm these initial results." | 1.27 | Desipramine plasma concentration and therapeutic response in elderly depressives: a naturalistic pilot study. ( Kutcher, SP; Reed, K; Shulman, KI, 1986) |
| " In each patient, tinnitus subsided spontaneously within 2-4 weeks of onset without any specific treatment, even though the daily dosage of imipramine and the plasma tricyclic levels were constant or increased." | 1.27 | Imipramine and tinnitus. ( Greden, JF; Grunhaus, L; Tandon, R, 1987) |
| "A low dosage of the specific MAO-A inhibitor clorgyline (5-10 mg/day) was administered chronically to 10 depressed patients." | 1.27 | The effect of clorgyline on noradrenergic function. ( Hauger, RL; Lesieur, P; Linnoila, M; Potter, WZ; Ross, RJ; Rudorfer, MV; Scheinin, M; Siever, LJ, 1985) |
| " Following a series of controlled dosage decreases, from 400 to 50 mg/day, the patient's steady state serum concentrations fit a nonlinear pharmacokinetic model." | 1.27 | Nonlinear desipramine pharmacokinetics: a case study. ( Bishop, DS; Dugas, JE, 1985) |
| " Her elimination half-life for desipramine was found to be greatly prolonged, at approximately 150 hours." | 1.27 | Idiosyncratic pharmacokinetics complicating treatment of major depression in an elderly woman. ( Dugas, JE; Glassman, JN; Loyd, DW; Tsuang, MT, 1985) |
| " Chronic administration of imipramine-HCl (1 and 5 mg/kg, i." | 1.27 | Effects of antidepressant drugs on a quickly-learned conditioned-suppression response in mice. ( Kameyama, T; Nagasaka, M; Yamada, K, 1985) |
| " Based on amino acid patterns and serum drug levels only half of the patients received an optimal therapy on the applied schematic dosage schedule." | 1.27 | Biochemical and diagnostic classification and serum drug levels: relation to antidepressive effect of imipramine. ( Elley, J; Krautwald, O; Larsen, OB; Møller, SE; Ortmann, J; Reisby, N, 1985) |
| "Melatonin secretion was significantly increased after three weeks of treatment in depressed patients." | 1.27 | The effect of desipramine upon melatonin and cortisol secretion in depressed and normal subjects. ( Arendt, J; Checkley, SA; Corn, T; English, J; Franey, C; Mezey, G; Thompson, C, 1985) |
| "Symptomatic orthostatic hypotension, the most common side effect encountered, occurred early in treatment at low desipramine plasma concentrations." | 1.26 | Major adverse reactions during desipramine treatment: relationship to plasma drug concentrations, concomitant antipsychotic treatment, and patient characteristics. ( Bock, J; Bowers, MB; Jatlow, PI; Nelson, JC; Quinlan, DM, 1982) |
| "Desipramine plasma was much more effective than zimelidine plasma in inhibiting NA uptake in the same preparation." | 1.26 | A double-blind study of zimelidine, a serotonin uptake inhibitor, and desipramine, a noradrenaline uptake inhibitor, in endogenous depression. II. Biochemical findings. ( Aberg-Wistedt, A; Jostell, KG; Ross, SB; Sjöquist, B, 1982) |
| " Because of the frequent chronic use of antidepressants in treatment of depression, we investigated the in vivo effects of desmethylimipramine and lithium carbonate on sperm function in patients suffering from clinical depression." | 1.26 | Effects of psychotropic drugs on human sperm motility. ( Amsterdam, JD; Levin, RM; Wein, AJ; Winokur, A, 1981) |
| "A 24-year-old woman with a unipolar depression had an augmented thyroid-stimulating hormone response to thyrotropin-releasing hormone (TRH), suggesting subclinical hypothyroidism." | 1.26 | Does subclinical hypothyroidism predispose to tricyclic-induced rapid mood cycles? ( Extein, I; Gold, MS; Pottash, AL, 1982) |
| "Desipramine was given at a dose of 50-100 mg/day for 3-5 weeks." | 1.26 | Abnormal anterior pituitary responsiveness to hypothalamic hormones in primary affective disorders. Effect of desipramine therapy. ( Brambilla, F; Massironi, R; Nobile, P; Pugnetti, L; Scarone, S, 1982) |
| " An inverse correlation between plasma levels of DMI and plasma levels of melatonin-like immunoreactivity was found in the group of clinical responders to the chronic administration of the drug." | 1.26 | An inverse correlation between serum levels of desmethylimipramine and melatonin-like immunoreactivity in DMI-responsive depressives. ( Halbreich, U; Klein, DF; Quitkin, FM; Stewart, J; Weinberg, U; Weitzman, ED, 1981) |
| " The single dose clearance technique yielded a precise criterion for quantitating early compliance with and adjusting drug dosing regimens." | 1.26 | Estimating steady state desipramine levels in noninstitutionalized elderly patients using single dose disposition parameters. ( Alderson, LM; Antal, EJ; Chapron, DJ; Kramer, PA; Lawson, IR, 1982) |
| " Ten initial nonresponders were converted to responders when dosage increase raised desipramine plasma concentration to 125 ng/mL or above." | 1.26 | Desipramine plasma concentration and antidepressant response. ( Bowers, MB; Jatlow, P; Nelson, JC; Quinlan, DM, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 298 (52.46) | 18.7374 |
| 1990's | 205 (36.09) | 18.2507 |
| 2000's | 49 (8.63) | 29.6817 |
| 2010's | 16 (2.82) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sales, AJ | 1 |
| Crestani, CC | 1 |
| Guimarães, FS | 1 |
| Joca, SRL | 1 |
| Preskorn, SH | 9 |
| Comai, S | 1 |
| Ochoa-Sanchez, R | 1 |
| Dominguez-Lopez, S | 1 |
| Bambico, FR | 1 |
| Gobbi, G | 1 |
| Olivares-Nazario, M | 1 |
| Fernández-Guasti, A | 1 |
| Martínez-Mota, L | 1 |
| Shah, AP | 1 |
| Carreno, FR | 1 |
| Wu, H | 1 |
| Chung, YA | 1 |
| Frazer, A | 5 |
| Wang, W | 1 |
| Xiang, ZH | 1 |
| Jiang, CL | 1 |
| Liu, WZ | 1 |
| Shang, ZL | 1 |
| Wang, DD | 1 |
| Li, J | 1 |
| Yu, LP | 1 |
| Wu, MN | 1 |
| Sun, LN | 1 |
| Qi, JS | 1 |
| Stasiuk, W | 1 |
| Szopa, A | 1 |
| Serefko, A | 1 |
| Wyska, E | 1 |
| Świąder, K | 1 |
| Dudka, J | 1 |
| Wlaź, P | 1 |
| Poleszak, E | 1 |
| Gonzáles, MA | 1 |
| Miranda, AP | 1 |
| Orrego, H | 1 |
| Silva, R | 1 |
| Forray, MI | 1 |
| Spencer, TJ | 3 |
| Perona, MT | 1 |
| Waters, S | 1 |
| Hall, FS | 1 |
| Sora, I | 1 |
| Lesch, KP | 1 |
| Murphy, DL | 2 |
| Caron, M | 1 |
| Uhl, GR | 1 |
| Jeannotte, AM | 1 |
| McCarthy, JG | 1 |
| Redei, EE | 2 |
| Sidhu, A | 1 |
| Okun, MS | 1 |
| Fernandez, HH | 1 |
| Friedman, A | 2 |
| Merenlender, A | 1 |
| Lax, E | 1 |
| Rosenstein, M | 2 |
| Lubin, N | 1 |
| Yadid, G | 3 |
| Hu, B | 1 |
| Doods, H | 1 |
| Treede, RD | 1 |
| Ceci, A | 1 |
| Bantsiele, GB | 1 |
| Bentué-Ferrer, D | 1 |
| Saïkali, S | 1 |
| Laviolle, B | 1 |
| Bourin, M | 2 |
| Reymann, JM | 1 |
| Shen, Q | 1 |
| Lal, R | 1 |
| Luellen, BA | 1 |
| Earnheart, JC | 1 |
| Andrews, AM | 1 |
| Luscher, B | 1 |
| Huang, TY | 1 |
| Lin, CH | 1 |
| Lin, Y | 1 |
| Suckow, RF | 4 |
| Sarfraz, Y | 1 |
| Stone, EA | 1 |
| Himmerich, H | 1 |
| Fulda, S | 1 |
| Sheldrick, AJ | 1 |
| Plümäkers, B | 1 |
| Rink, L | 1 |
| Rastogi, R | 1 |
| Swarm, RA | 1 |
| Patel, TA | 1 |
| Demirtas, H | 1 |
| Doganay, B | 1 |
| Pechlivanova, DM | 1 |
| Tchekalarova, JD | 1 |
| Alova, LH | 1 |
| Petkov, VV | 1 |
| Nikolov, RP | 1 |
| Yakimova, KS | 1 |
| Gilmor, ML | 1 |
| Owens, MJ | 1 |
| Nemeroff, CB | 1 |
| Finkelstein, FO | 1 |
| Watnick, S | 1 |
| Finkelstein, SH | 1 |
| Wuerth, D | 1 |
| Dawson, LA | 1 |
| Li, P | 1 |
| Bremner, JD | 1 |
| Vythilingam, M | 1 |
| Ng, CK | 1 |
| Vermetten, E | 1 |
| Nazeer, A | 1 |
| Oren, DA | 1 |
| Berman, RM | 1 |
| Charney, DS | 17 |
| BAN, TA | 1 |
| LEHMANN, HE | 2 |
| FRAME, MC | 1 |
| POELDINGER, W | 2 |
| KRAKOWSKI, AJ | 2 |
| OLESEN, KM | 1 |
| ROLLE, T | 1 |
| MARKETTE, JR | 1 |
| HARRIS, TH | 1 |
| CMYRAL, K | 1 |
| HOFMANN, G | 1 |
| ALNAES, R | 2 |
| KRISTIANSEN, J | 2 |
| VOLTERRA, V | 1 |
| GUERMANI, M | 1 |
| SEGERS, J | 1 |
| NUYTS, JA | 1 |
| SHIOSAKI, S | 1 |
| TAKASHIO, T | 1 |
| HOSAKA, K | 1 |
| ROSE, JT | 1 |
| WESTHEAD, TT | 1 |
| ENGELMEIER, MP | 1 |
| BARRINGER, TJ | 1 |
| HORDERN, A | 1 |
| LAPOLLA, A | 1 |
| POLLITT, J | 1 |
| WALDRON, J | 1 |
| BATES, TJ | 1 |
| MANN, AM | 1 |
| OLTMAN, JE | 1 |
| FRIEDMAN, S | 1 |
| Will, CC | 1 |
| Aird, F | 1 |
| Perlis, RH | 1 |
| Alpert, J | 2 |
| Nierenberg, AA | 2 |
| Mischoulon, D | 2 |
| Yeung, A | 1 |
| Rosenbaum, JF | 7 |
| Fava, M | 4 |
| Dremencov, E | 2 |
| Gispan-Herman, I | 1 |
| Mendelman, A | 1 |
| Overstreet, DH | 2 |
| Zohar, J | 2 |
| Nelson, JC | 29 |
| Mazure, CM | 7 |
| Jatlow, PI | 18 |
| Bowers, MB | 4 |
| Price, LH | 14 |
| Schildkraut, JJ | 2 |
| Mooney, JJ | 2 |
| Papakostas, GI | 1 |
| Petersen, T | 1 |
| Ryan, JL | 1 |
| Bottiglieri, T | 1 |
| Alpert, JE | 1 |
| Licinio, J | 1 |
| O'Kirwan, F | 1 |
| Irizarry, K | 1 |
| Merriman, B | 1 |
| Thakur, S | 1 |
| Jepson, R | 1 |
| Lake, S | 1 |
| Tantisira, KG | 1 |
| Weiss, ST | 1 |
| Wong, ML | 1 |
| Avissar, S | 1 |
| Matuzany-Ruban, A | 1 |
| Tzukert, K | 1 |
| Schreiber, G | 1 |
| Thangathurai, D | 1 |
| Roffey, P | 1 |
| Mogos, M | 1 |
| Riad, M | 1 |
| Mikhail, M | 1 |
| DeRubeis, RJ | 2 |
| Hollon, SD | 2 |
| Amsterdam, JD | 7 |
| Shelton, RC | 2 |
| Young, PR | 1 |
| Salomon, RM | 2 |
| O'Reardon, JP | 2 |
| Lovett, ML | 1 |
| Gladis, MM | 1 |
| Brown, LL | 1 |
| Gallop, R | 1 |
| Chow, BJ | 1 |
| Gollob, M | 1 |
| Birnie, D | 1 |
| Ma, G | 1 |
| Troxel, AB | 1 |
| Heitjan, DF | 1 |
| McDowell, D | 1 |
| Nunes, EV | 1 |
| Seracini, AM | 1 |
| Rothenberg, J | 1 |
| Vosburg, SK | 1 |
| Ma, GJ | 1 |
| Petkova, E | 1 |
| Kurpius, MP | 1 |
| Alexander, B | 1 |
| Monteggia, LM | 1 |
| Luikart, B | 1 |
| Barrot, M | 1 |
| Theobold, D | 1 |
| Malkovska, I | 1 |
| Nef, S | 1 |
| Parada, LF | 1 |
| Nestler, EJ | 1 |
| Chenu, F | 1 |
| Guiard, BP | 1 |
| Gardier, AM | 1 |
| Khundakar, AA | 1 |
| Zetterström, TSC | 1 |
| Lapiz, MD | 2 |
| Bondi, CO | 2 |
| Morilak, DA | 2 |
| Piletz, J | 1 |
| Baker, R | 1 |
| Halaris, A | 8 |
| Crozatier, C | 1 |
| Farley, S | 1 |
| Mansuy, IM | 1 |
| Dumas, S | 1 |
| Giros, B | 1 |
| Tzavara, ET | 1 |
| Schulz, D | 1 |
| Buddenberg, T | 1 |
| Huston, JP | 1 |
| Schenk, PW | 1 |
| van Fessem, MA | 1 |
| Verploegh-Van Rij, S | 1 |
| Mathot, RA | 1 |
| van Gelder, T | 1 |
| Vulto, AG | 1 |
| van Vliet, M | 1 |
| Lindemans, J | 1 |
| Bruijn, JA | 2 |
| van Schaik, RH | 1 |
| Samson, JA | 2 |
| Hennen, J | 1 |
| Pappalardo, K | 1 |
| McHale, N | 1 |
| Koutsos, M | 1 |
| Saxon, AJ | 1 |
| Gass, P | 1 |
| Riva, MA | 1 |
| Reed, AL | 1 |
| Happe, HK | 1 |
| Petty, F | 3 |
| Bylund, DB | 1 |
| Friedman, Y | 1 |
| Birkenhager, TK | 1 |
| van den Broek, WW | 1 |
| Mulder, PG | 1 |
| Moleman, P | 1 |
| Zhao, Z | 1 |
| Baros, AM | 1 |
| Zhang, HT | 1 |
| O'Donnell, JM | 1 |
| Jama, A | 1 |
| Cecchi, M | 1 |
| Calvo, N | 1 |
| Watson, SJ | 1 |
| Akil, H | 1 |
| Matussek, N | 2 |
| Mavroidis, ML | 1 |
| Kanter, DR | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Study of Antidepressants in Parkinson's Disease[NCT00086190] | Phase 3 | 115 participants (Actual) | Interventional | 2005-06-30 | Completed | ||
| A Pilot Study of Duloxetine in Psychological Resilience and Its Correlation With Blockade of Serotonin and Norepinephrine Transporter[NCT00331799] | Phase 2 | 18 participants (Actual) | Interventional | 2007-04-30 | Completed | ||
| [NCT00265291] | Phase 2 | 700 participants (Actual) | Interventional | 1999-11-30 | Completed | ||
| The Role of Negr1 In Modulating Neuroplasticity in Major Depression (RONIN)[NCT06131268] | Phase 4 | 30 participants (Anticipated) | Interventional | 2022-03-01 | Recruiting | ||
| Assessing the Effectiveness of a CBT-based App in Reducing Suicidal Ideation: An Open Randomized Study[NCT04414774] | 128 participants (Actual) | Interventional | 2020-06-14 | Completed | |||
| The Women In Steady Exercise Research (WISER) Survivor Trial & Cost of Illness and Cost Effectiveness of Alternative Management Strategies[NCT01515124] | 450 participants (Actual) | Interventional | 2012-01-31 | Completed | |||
| [NCT00037362] | 0 participants | Observational | 2001-09-30 | Completed | |||
| New Approaches to Cocaine Abuse Medications (A)[NCT00000271] | Phase 2 | 111 participants (Actual) | Interventional | 1995-01-31 | Completed | ||
| Psychopharmacology of Biogenic Amines in Depression[NCT00320632] | Phase 4 | 43 participants | Interventional | 1990-08-31 | Completed | ||
| Conscious Dying/Conscious Living: Ketamine-Assisted Psychotherapy (KAP) for Patients at End of Life-A Pilot Study for Palliative and Hospice Care[NCT05214417] | Phase 2 | 120 participants (Anticipated) | Interventional | 2022-05-01 | Not yet recruiting | ||
| Motivational Interviewing to Reduce Substance Use Among Depression Patients[NCT02420561] | 307 participants (Actual) | Interventional | 2010-10-31 | Completed | |||
| [NCT00005461] | 0 participants | Observational | 1991-04-30 | Completed | |||
| Neural Correlates of Depressive Symptoms and Reward Related Mechanisms Following AMPT Depletion in Remitted Depressed Patients Off Treatment and Healthy Controls[NCT00082030] | 71 participants (Actual) | Observational | 2004-04-19 | Completed | |||
| Optimizing Treatment for Complicated Grief (Healing Emotions After Loss:HEAL)[NCT01179568] | Phase 2 | 395 participants (Actual) | Interventional | 2010-03-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Beck Depression Inventory II ranges from 0-63. Higher score indicates more severe depression. 0-13 minimal depression, 14-19 mild depression, 20-28 moderate depression, 29-63 severe depression. (NCT00086190)
Timeframe: from the beginning (0 weeks) to end (12 weeks) of the double-blind phase
| Intervention | Change in BDI-II score (Mean) |
|---|---|
| Paroxetine | -9.7 |
| Venlafaxine Extended Release | -9.6 |
| Placebo | -5.2 |
Brief Psychiatric Rating Scale. Maximum score 126. Higher score indicates greater psychiatric difficulties. (NCT00086190)
Timeframe: from the beginning (0 weeks) to end (12 weeks) of the double-blind phase
| Intervention | Change in BPRS score (Mean) |
|---|---|
| Paroxetine | -9.0 |
| Venlafaxine Extended Release | -9.8 |
| Placebo | -4.4 |
Geriatric Depression Scale ranges from 0-30. Higher score indicates more severe depression. 0-9 normal, 10-19 mild depression, 20-30 severe depression. (NCT00086190)
Timeframe: from the beginning (0 weeks) to end (12 weeks) of the double-blind phase
| Intervention | Change in GDS score (Mean) |
|---|---|
| Paroxetine | -6.9 |
| Venlafaxine Extended Release | -6.9 |
| Placebo | -2.8 |
Change in Hamilton Rating Scale for Depression over 12 weeks. Hamilton Depression Rating Scale ranges from 0-50. Higher scores represent more significant depression. Mild depression ranges from 8-13, moderate depression from 14-18, severe 19-22 and very severe any score over 23. (NCT00086190)
Timeframe: from the beginning (0 weeks) to end (12 weeks) of the double-blind phase
| Intervention | Change in HAM-D score (Mean) |
|---|---|
| Paroxetine | -13.0 |
| Venlafaxine Extended Release | -11.0 |
| Placebo | -6.8 |
Montgomery-Asberg Depression Rating Scale ranges from 0-60. Higher score indicates more severe depression. 0-6 normal, 7-19 mild depression, 20-34 moderate depression, greater than 34 severe depression. (NCT00086190)
Timeframe: from the beginning (0 weeks) to end (12 weeks) of the double-blind phase
| Intervention | Change in MADRS score (Mean) |
|---|---|
| Paroxetine | -13.6 |
| Venlafaxine Extended Release | -10.9 |
| Placebo | -6.6 |
Parkinson's Disease Questionnaire (PDQ-39) - Emotional Well-Being maximum score 24, minimum score of 0.Lower score indicates a better perceived health status. (NCT00086190)
Timeframe: from the beginning (0 weeks) to end (12 weeks) of the double-blind phase
| Intervention | Change in PDQ-39 Emotional score (Mean) |
|---|---|
| Paroxetine | -21.4 |
| Venlafaxine Extended Release | -20.7 |
| Placebo | -10.9 |
Parkinson's Disease Questionnaire (PDQ-39) Total. Range 0-100. Lower score indicates a better perceived health status. (NCT00086190)
Timeframe: from the beginning (0 weeks) to end (12 weeks) of the double-blind phase
| Intervention | Change in PDQ-39 score (Mean) |
|---|---|
| Paroxetine | -8.0 |
| Venlafaxine Extended Release | -8.4 |
| Placebo | -5.3 |
Pittsburgh Sleep Quality Index scores range from 0-21, with higher scores indicating severe sleep difficulties. (NCT00086190)
Timeframe: from the beginning (0 weeks) to end (12 weeks) of the double-blind phase
| Intervention | Change in PQSI score (Mean) |
|---|---|
| Paroxetine | -2.1 |
| Venlafaxine Extended Release | -2.6 |
| Placebo | -1.1 |
Short Form 36 Health Survey. Range 0-100. Higher score indicates a better perceived quality of life. (NCT00086190)
Timeframe: from the beginning (0 weeks) to end (12 weeks) of the double-blind phase
| Intervention | Change in SF-36 mental score (Mean) |
|---|---|
| Paroxetine | 11.4 |
| Venlafaxine Extended Release | 9.5 |
| Placebo | 4.8 |
Short Form 36 Health Survey - Mental Health subscale ranges from 0-100. Higher score indicates a better perceived quality of life. (NCT00086190)
Timeframe: from the beginning (0 weeks) to end (12 weeks) of the double-blind phase
| Intervention | Change in SF-36 Mental Health score (Mean) |
|---|---|
| Paroxetine | 16.7 |
| Venlafaxine Extended Release | 17.4 |
| Placebo | 9.7 |
Short Form 36 Health Survey - Emotional subscale ranges from 0-100. Higher score indicates a better perceived quality of life. (NCT00086190)
Timeframe: from the beginning (0 weeks) to end (12 weeks) of the double-blind phase
| Intervention | Change in SF-36 Role score (Mean) |
|---|---|
| Paroxetine | 39.5 |
| Venlafaxine Extended Release | 26.9 |
| Placebo | 12.7 |
Short Form 36 Health Survey - Vitality subscale ranges from 0-100. Higher score indicates a better perceived quality of life. (NCT00086190)
Timeframe: from the beginning (0 weeks) to end (12 weeks) of the double-blind phase
| Intervention | Change in SF-36 vitality score (Mean) |
|---|---|
| Paroxetine | 13.5 |
| Venlafaxine Extended Release | 9.1 |
| Placebo | 4.7 |
Snaith Clinical Anxiety Scale. Range 0-21. Higher scores indicate increased anxiety. Score greater than 8 indicates clinical anxiety. (NCT00086190)
Timeframe: from the beginning (0 weeks) to end (12 weeks) of the double-blind phase
| Intervention | Change in CAS score (Mean) |
|---|---|
| Paroxetine | -3.6 |
| Venlafaxine Extended Release | -3.2 |
| Placebo | -2.4 |
Unified Parkinson's Disease Rating Scale. Higher score indicates more severe Parkinson's disease symptoms. Total maximum = 176. Mental maximum = 52, Activities of Daily Living maximum = 52, Motor maximum = 72. Minimum = 0. (NCT00086190)
Timeframe: from the beginning (0 weeks) to end (12 weeks) of the double-blind phase
| Intervention | Change in UPDRS score (Mean) |
|---|---|
| Paroxetine | -8.7 |
| Venlafaxine Extended Release | -7.0 |
| Placebo | -4.3 |
Unified Parkinson's Disease Rating Scale - Bulbar maximum score 24, minimum score of 0. Higher score indicates more severe Parkinson's disease symptoms. (NCT00086190)
Timeframe: from the beginning (0 weeks) to end (12 weeks) of the double-blind phase
| Intervention | Change in UPDRS-Bulbar score (Mean) |
|---|---|
| Paroxetine | -1.4 |
| Venlafaxine Extended Release | -1.4 |
| Placebo | -0.5 |
Unified Parkinson's Disease Rating Scale - Motor has a maximum score of 72, minimum score of 0. Higher score indicates more severe Parkinson's disease symptoms. (NCT00086190)
Timeframe: from the beginning (0 weeks) to end (12 weeks) of the double-blind phase
| Intervention | Change in UPDRS-motor score (Mean) |
|---|---|
| Paroxetine | -4.3 |
| Venlafaxine Extended Release | -2.0 |
| Placebo | -1.0 |
Unified Parkinson's Disease Rating Scale - Tremor subscale ranges from 0-23. Higher score indicates more severe Parkinson's disease symptoms. (NCT00086190)
Timeframe: from the beginning (0 weeks) to end (12 weeks) of the double-blind phase
| Intervention | Change in UPDRS-tremor score (Mean) |
|---|---|
| Paroxetine | 0.4 |
| Venlafaxine Extended Release | 0.5 |
| Placebo | -0.6 |
CD-RISC has been psychometrically validated, studied in the general population, as well as in clinical samples. Changes in CD-RISC score have been found to be sensitive to the effect of treatment, and impaired resilience has been demonstrated in subjects with depression relative to normal controls using this scale (Connor and Davidson, 2003). The total score ranges from 0-100, with higher scores indicating greater resilience. (NCT00331799)
Timeframe: baseline and 8 weeks
| Intervention | units on a scale (Mean) |
|---|---|
| Duloxetine | 52.62 |
The 19-item self-report instrument assesses symptoms of complicated grief. Responses on individual items are added up to a total score, which can range from 0 to 76 with higher scores indicating more intense symptoms. This scale has been utilized previously in treatment studies of CG. Additional times points include weeks 4, 8, 12, 16, 20 and 40. For the pre-specified analyses we compared change in the ICG total score from baseline (calculated as baseline score minus week 12 score) for CIT vs PLA at week 12 (aim 1), based on the intention-to-treat principle including all randomized participants. (NCT01179568)
Timeframe: Baseline and week 12
| Intervention | score change from baseline to wk12 (Mean) |
|---|---|
| Citalopram (CIT) | 18 |
| Placebo (PLA; Sugar Pill) | 16 |
The 19-item self-report instrument assesses symptoms of complicated grief. Responses on individual items are added up to a total score, which can range from 0 to 76 with higher scores indicating more intense symptoms. This scale has been utilized previously in treatment studies of CG. Additional times points include weeks 4, 8, 12, 16, 20 and 40. For the pre-specified analyses we compared change in the ICG total score from baseline (calculated as baseline score minus week 20 score) for CIT with CGT vs PLA with CGT (aim 2), and for CIT with CGT vs CIT (aim 3) based on the intention-to-treat principle including all randomized participants. (NCT01179568)
Timeframe: Baseline and week 20
| Intervention | score change from baseline to wk20 (Mean) |
|---|---|
| Citalopram (CIT) | 20 |
| Complicated Grief Treatment With Citalopram (CGT With CIT) | 25 |
| Complicated Grief Treatment With Placebo (CGT With PLA) | 26 |
The WSAS is a modification of a scale introduced by Hafner and Marks (1976), consisting of 0-8 point ratings of the extent to which symptoms interfere with five areas of daily functioning: work, home management, private leisure, social leisure, and family relationships. It is a well-validated, widely used self-report measure. Additional time points include weeks 4, 8, 12, 16, and 40. A total score calculated as a sum of all items (possible range 0-40) was used in the analyses with higher scores indicating more impairment. For the pre-specified analyses we compared change in the WSAS total score from baseline (calculated as baseline score minus week 12 score) for CIT vs PLA at week 12 (aim 1), based on the intention-to-treat principle including all randomized participants. (NCT01179568)
Timeframe: Baseline and week 12
| Intervention | score change from baseline to wk12 (Mean) |
|---|---|
| Citalopram (CIT) | 10 |
| Placebo (PLA; Sugar Pill) | 8 |
The WSAS is a modification of a scale introduced by Hafner and Marks (1976), consisting of 0-8 point ratings of the extent to which symptoms interfere with five areas of daily functioning: work, home management, private leisure, social leisure, and family relationships. It is a well-validated, widely used self-report measure. Additional time points include weeks 4, 8, 12, 16, and 40. A total score calculated as a sum of all items (possible range 0-40) was used in the analyses with higher scores indicating more impairment. For the pre-specified analyses we compared change in the WSAS total score from baseline (calculated as baseline score minus week 20 score) for CIT with CGT vs PLA with CGT (aim 2), and for CIT with CGT vs CIT (aim 3) based on the intention-to-treat principle including all randomized participants. (NCT01179568)
Timeframe: Baseline and week 20
| Intervention | score change from baseline to wk20 (Mean) |
|---|---|
| Citalopram (CIT) | 10 |
| Complicated Grief Treatment With Citalopram (CGT With CIT) | 14 |
| Complicated Grief Treatment With Placebo (CGT With PLA) | 16 |
Brief rating scale frequently used in clinical trials. For this study, version modified for complicated grief was be used. Response is defined as a score of 1(very much improved) or 2 (much improved) on the scale. The rating was done by an Independent Evaluator. (NCT01179568)
Timeframe: Weeks 12 and 20
| Intervention | percentage of responders (Number) |
|---|---|
| Citalopram (CIT) | 46 |
| Placebo (PLA; Sugar Pill) | 38 |
| Complicated Grief Treatment With Citalopram (CGT With CIT) | 84 |
| Complicated Grief Treatment With Placebo (CGT With PLA) | 83 |
36 reviews available for desipramine and Depression, Endogenous
| Article | Year |
|---|---|
Clinical psychopharmacology and medical malpractice: the four Ds.
Topics: Adult; Antidepressive Agents; Antipsychotic Agents; Attention Deficit Disorder with Hyperactivity; C | 2014 |
Case scenario: opioid association with serotonin syndrome: implications to the practitioners.
Topics: Analgesics, Opioid; Antidepressive Agents, Tricyclic; Celecoxib; Chronic Pain; Cyclooxygenase 2 Inhi | 2011 |
The treatment of depression in patients maintained on dialysis.
Topics: Antidepressive Agents, Tricyclic; Depressive Disorder; Desipramine; Fluoxetine; Humans; Kidney Failu | 2002 |
THE PHARMACOTHERAPY OF THE DEPRESSIVE SYNDROME.
Topics: Amitriptyline; Antidepressive Agents; Convulsive Therapy; Depression; Depressive Disorder; Desiprami | 1965 |
THE ANTIDEPRESSANT DRUGS.
Topics: Amitriptyline; Antidepressive Agents; Central Nervous System Stimulants; Depression; Depressive Diso | 1965 |
CREB, neurogenesis and depression.
Topics: Animals; Antidepressive Agents; Cyclic AMP Response Element-Binding Protein; Depressive Disorder; De | 2007 |
Drugs as tools for exploring neuroendocrine functions.
Topics: Alcoholism; Clonidine; Depressive Disorder; Desipramine; Female; Growth Hormone; Humans; Insulin; Ma | 1984 |
Regulation of neurotransmitter receptors by desipramine and other antidepressant drugs: the neurotransmitter receptor hypothesis of antidepressant action.
Topics: Albuterol; Antidepressive Agents; Clenbuterol; Depressive Disorder; Desipramine; Humans; Models, Mol | 1984 |
Newer uses for older psychotropic medications.
Topics: Adrenergic beta-Antagonists; Agoraphobia; Anxiety Disorders; Bipolar Disorder; Clonidine; Depressive | 1982 |
Psychopharmacologic treatment of depression.
Topics: Affective Disorders, Psychotic; Antidepressive Agents; Antidepressive Agents, Tricyclic; Antipsychot | 1984 |
Binding of [3H]imipramine and [3H]desipramine as biochemical tools for studies in depression.
Topics: Animals; Antidepressive Agents, Tricyclic; Blood Platelets; Brain; Carrier Proteins; Depressive Diso | 1983 |
[Neurobiologic aspects of depression].
Topics: Amphetamine; Animals; Blood Platelets; Cholinergic Fibers; Clonidine; Depressive Disorder; Desiprami | 1983 |
3H-imipramine and 3H-desipramine binding sites in depression.
Topics: Animals; Antidepressive Agents; Binding Sites; Biogenic Amines; Biological Transport; Blood Platelet | 1984 |
Antidepressant binding sites in brain.
Topics: Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Binding Sites; Blood Platelets; Br | 1984 |
Use of desipramine in depressed inpatients.
Topics: Age Factors; Clinical Trials as Topic; Delusions; Depressive Disorder; Desipramine; Dose-Response Re | 1984 |
Treatment of outpatients with desipramine.
Topics: Ambulatory Care; Anxiety Disorders; Body Weight; Depressive Disorder; Desipramine; Drug Administrati | 1984 |
Desipramine: an overview.
Topics: Clinical Trials as Topic; Depressive Disorder; Desipramine; Dose-Response Relationship, Drug; Drug U | 1984 |
Relationship of desipramine plasma levels to therapeutic response: a critical reappraisal of the data.
Topics: Ambulatory Care; Depressive Disorder; Desipramine; Dose-Response Relationship, Drug; Drug Administra | 1984 |
Implications of dosing tricyclic antidepressants and benzodiazepines in geriatrics.
Topics: Adipose Tissue; Adult; Aged; Aging; Amitriptyline; Antidepressive Agents, Tricyclic; Anxiety Disorde | 1984 |
Tricyclic antidepressant concentrations in plasma: an estimate of their sensitivity and specificity as a predictor of response.
Topics: Adolescent; Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Clinical Trials as Topic; Depres | 1994 |
Polymorphism in the metabolism of drugs, including antidepressant drugs: comments on phenotyping.
Topics: Clomipramine; Cytochromes; Dealkylation; Depressive Disorder; Desipramine; Dextromethorphan; Drug In | 1994 |
[Pharmacological treatment of delusional depression].
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Delusions; Depressive Disorde | 1996 |
Cardiovascular effects of tricyclic antidepressants in childhood asthma: a case series and review.
Topics: Adolescent; Anti-Inflammatory Agents; Antidepressive Agents, Tricyclic; Anxiety Disorders; Asthma; B | 1997 |
Augmentation strategies with serotonergic-noradrenergic combinations.
Topics: Adrenergic Uptake Inhibitors; Antidepressive Agents; Antidepressive Agents, Tricyclic; Bupropion; Cl | 1998 |
Noradrenergic versus serotonergic antidepressants: predictors of treatment response.
Topics: Adrenergic Uptake Inhibitors; Catecholamines; Clinical Trials as Topic; Depressive Disorder; Desipra | 1998 |
Norepinephrine involvement in antidepressant action.
Topics: Adrenergic Uptake Inhibitors; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antid | 2000 |
The emergence of suicidal ideation and behavior during antidepressant pharmacotherapy.
Topics: Antidepressive Agents; Depressive Disorder; Desipramine; Drug Therapy, Combination; Fluoxetine; Fluv | 1991 |
Toleration and safety of sertraline: experience worldwide.
Topics: 1-Naphthylamine; Amitriptyline; Antidepressive Agents; Depressive Disorder; Desipramine; Drug Overdo | 1991 |
Depression and cerebrovascular disease.
Topics: Cerebrovascular Disorders; Depressive Disorder; Desipramine; Female; Fluoxetine; Humans; Male; Nortr | 1990 |
Tricyclic antidepressants for medically ill geriatric patients.
Topics: Aged; Antidepressive Agents, Tricyclic; Depressive Disorder; Desipramine; Doxepin; Geriatrics; Human | 1989 |
[Antidepressant drugs and central monoaminergic receptors].
Topics: Adenylyl Cyclases; Animals; Antidepressive Agents; Antipsychotic Agents; Binding Sites; Blood Platel | 1985 |
Effect of desipramine treatment on 3H-imipramine binding in the blood platelets of depressed patients.
Topics: Adult; Blood Platelets; Depressive Disorder; Desipramine; Female; Humans; Male; Middle Aged; Tritium | 1988 |
Tricyclic antidepressants--blood level measurements and clinical outcome: an APA Task Force report. Task Force on the Use of Laboratory Tests in Psychiatry.
Topics: Antidepressive Agents, Tricyclic; Blood Chemical Analysis; Clinical Trials as Topic; Depressive Diso | 1985 |
Psychotropic drugs and the thyroid axis: a review of interactions.
Topics: Animals; Body Temperature; Brain; Chlorpromazine; Depressive Disorder; Desipramine; Drug Interaction | 1985 |
Tricyclic-resistant depression: treatment resistance or inadequate treatment?
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Depressive Disorder; Desipramine; Dose-Response Rel | 1985 |
The importance of dosage in prescribing antidepressants.
Topics: Antidepressive Agents, Tricyclic; Depressive Disorder; Desipramine; Dose-Response Relationship, Drug | 1985 |
152 trials available for desipramine and Depression, Endogenous
| Article | Year |
|---|---|
Inhibition of norepinephrine uptake in patients with major depression treated with paroxetine.
Topics: Adult; Ambulatory Care; Carrier Proteins; Depressive Disorder; Desipramine; Dose-Response Relationsh | 2002 |
Regional brain metabolic correlates of alpha-methylparatyrosine-induced depressive symptoms: implications for the neural circuitry of depression.
Topics: Adrenergic Uptake Inhibitors; Adult; alpha-Methyltyrosine; Antidepressive Agents, Tricyclic; Brain; | 2003 |
Clinical and sociodemographic predictors of response to augmentation, or dose increase among depressed outpatients resistant to fluoxetine 20 mg/day.
Topics: Adult; Antidepressive Agents, Tricyclic; Demography; Depressive Disorder; Desipramine; Dose-Response | 2003 |
Combining norepinephrine and serotonin reuptake inhibition mechanisms for treatment of depression: a double-blind, randomized study.
Topics: Adrenergic Uptake Inhibitors; Adult; Antidepressive Agents, Second-Generation; Antidepressive Agents | 2004 |
Serum folate, vitamin B12, and homocysteine in major depressive disorder, Part 1: predictors of clinical response in fluoxetine-resistant depression.
Topics: Adult; Ambulatory Care; Antidepressive Agents, Tricyclic; Depressive Disorder; Desipramine; Double-B | 2004 |
Association of a corticotropin-releasing hormone receptor 1 haplotype and antidepressant treatment response in Mexican-Americans.
Topics: Adult; Antidepressive Agents; Anxiety; Depressive Disorder; Desipramine; Double-Blind Method; Female | 2004 |
Cognitive therapy vs medications in the treatment of moderate to severe depression.
Topics: Adult; Ambulatory Care; Antidepressive Agents; Cognitive Behavioral Therapy; Depressive Disorder; De | 2005 |
Cognitive therapy vs medications in the treatment of moderate to severe depression.
Topics: Adult; Ambulatory Care; Antidepressive Agents; Cognitive Behavioral Therapy; Depressive Disorder; De | 2005 |
Cognitive therapy vs medications in the treatment of moderate to severe depression.
Topics: Adult; Ambulatory Care; Antidepressive Agents; Cognitive Behavioral Therapy; Depressive Disorder; De | 2005 |
Cognitive therapy vs medications in the treatment of moderate to severe depression.
Topics: Adult; Ambulatory Care; Antidepressive Agents; Cognitive Behavioral Therapy; Depressive Disorder; De | 2005 |
Desipramine treatment of cocaine-dependent patients with depression: a placebo-controlled trial.
Topics: Adult; Antidepressive Agents, Tricyclic; Cocaine-Related Disorders; Cognitive Behavioral Therapy; Co | 2005 |
Platelet imidazoline receptors as state marker of depressive symptomatology.
Topics: Adult; Antidepressive Agents, Tricyclic; Blood Platelets; Brief Psychiatric Rating Scale; Depressive | 2008 |
Hormonal responses to zimelidine and desipramine in depressed patients.
Topics: Adolescent; Adult; Aged; Brain; Clinical Trials as Topic; Depressive Disorder; Desipramine; Double-B | 1984 |
Antidepressant effect of femoxetine and desipramine and relationship to the concentration of amine metabolites in cerebrospinal fluid. A double-blind evaluation.
Topics: Adult; Aged; Antidepressive Agents; Depressive Disorder; Desipramine; Double-Blind Method; Female; G | 1982 |
Five antidepressant treatments in depressed patients. Effects on urinary serotonin and 5-hydroxyindoleacetic acid output.
Topics: Antidepressive Agents; Clorgyline; Depressive Disorder; Desipramine; Electroconvulsive Therapy; Fema | 1984 |
A double-blind study of zimelidine, a serotonin uptake inhibitor, and desipramine, a norepinephrine uptake inhibitor, in endogenous depression: clinical and biochemical findings.
Topics: Adult; Aged; Clinical Trials as Topic; Depressive Disorder; Desipramine; Female; Homovanillic Acid; | 1984 |
Efficacy of desipramine in endogenomorphically depressed patients.
Topics: Adjustment Disorders; Adolescent; Adult; Clinical Trials as Topic; Clomipramine; Depressive Disorder | 1980 |
Alteration of norepinephrine metabolism with desipramine and zimelidine in depressed patients.
Topics: Antidepressive Agents; Brain; Brompheniramine; Depressive Disorder; Desipramine; Female; Humans; Mal | 1982 |
A double-blind study of zimelidine, a serotonin uptake inhibitor, and desipramine, a noradrenaline uptake inhibitor, in endogenous depression. I. Clinical findings.
Topics: Adult; Aged; Antidepressive Agents; Bipolar Disorder; Brompheniramine; Depressive Disorder; Desipram | 1982 |
Comparison between zimelidine and desipramine in endogenous depression. A cross-over study.
Topics: Antidepressive Agents; Bipolar Disorder; Brompheniramine; Depressive Disorder; Desipramine; Double-B | 1982 |
A double-blind comparison of zimelidine and desipramine in endogenous depression.
Topics: Adolescent; Adult; Aged; Brompheniramine; Depressive Disorder; Desipramine; Double-Blind Method; Fem | 1983 |
Effects of antidepressant treatments on dopamine turnover in depressed patients.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Antidepressive Agents; Bipolar Disorder; Brompheniramine; Clo | 1983 |
A double blind comparison of the efficacy and safety of trazodone and imipramine in endogenous depression.
Topics: Adult; Clinical Trials as Topic; Depressive Disorder; Desipramine; Double-Blind Method; Female; Huma | 1983 |
Platelet serotonin uptake inhibition as a basis for monitoring antidepressant drug treatment.
Topics: Adult; Aged; Blood Platelets; Depressive Disorder; Desipramine; Female; Humans; Kinetics; Male; Midd | 1984 |
Antidepressants in concomitant chronic back pain and depression: doxepin and desipramine compared.
Topics: Adult; Anxiety Disorders; Back Pain; beta-Endorphin; Chronic Disease; Clinical Trials as Topic; Depr | 1984 |
Efficacy of desipramine in depressed outpatients. Response according to research diagnosis criteria diagnoses and severity of illness.
Topics: Adolescent; Adult; Ambulatory Care; Clinical Trials as Topic; Depression; Depressive Disorder; Desip | 1983 |
[Clinical experience with clomipramine (Hydiphen) and desipramine (Petytyl) by parenteral administration in the treatment of endogenous depression with signs of pharmacoresistance].
Topics: Adolescent; Adult; Aged; Clinical Trials as Topic; Clomipramine; Depressive Disorder; Desipramine; D | 1983 |
Duration of antidepressant drug treatment. What is an adequate trial?
Topics: Actuarial Analysis; Antidepressive Agents; Clinical Trials as Topic; Depressive Disorder; Desipramin | 1984 |
Use of desipramine in depressed inpatients.
Topics: Age Factors; Clinical Trials as Topic; Delusions; Depressive Disorder; Desipramine; Dose-Response Re | 1984 |
Desipramine: an overview.
Topics: Clinical Trials as Topic; Depressive Disorder; Desipramine; Dose-Response Relationship, Drug; Drug U | 1984 |
Lithium carbonate addition in tricyclic antidepressant-resistant unipolar depression. Correlations with the neurobiologic actions of tricyclic antidepressant drugs and lithium ion on the serotonin system.
Topics: Adult; Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Clinical Trials as Topic; Depressive D | 1983 |
Lithium carbonate augmentation of antidepressant treatment. An effective prescription for treatment-refractory depression.
Topics: Adult; Aged; Amitriptyline; Antidepressive Agents; Clinical Trials as Topic; Depressive Disorder; De | 1983 |
Combined thioridazine and desipramine: early antidepressant response.
Topics: Adult; Depressive Disorder; Desipramine; Drug Therapy, Combination; Female; Humans; Male; Thioridazi | 1984 |
Controlled cross-over study of a 5-HT uptake inhibiting and an NA uptake inhibiting antidepressant.
Topics: Antidepressive Agents; Brompheniramine; Depressive Disorder; Desipramine; Female; Humans; Male; Nore | 1981 |
Crossover study of zimelidine and desipramine in depression: evidence for amine specificity [proceedings].
Topics: Brompheniramine; Clinical Trials as Topic; Depressive Disorder; Desipramine; Double-Blind Method; Hu | 1981 |
Effects of zimelidine and desipramine on serotonin and noradrenaline uptake mechanisms in relation to plasma concentrations and to therapeutic effects during treatment of depression.
Topics: Animals; Antidepressive Agents; Blood Platelets; Brompheniramine; Depressive Disorder; Desipramine; | 1981 |
Thioridazine effect on desipramine plasma levels.
Topics: Adult; Depressive Disorder; Desipramine; Drug Interactions; Drug Therapy, Combination; Female; Human | 1983 |
Serotonin function and mechanism of action of antidepressant treatment. Effects of amitriptyline and desipramine.
Topics: Aged; Amitriptyline; Animals; Brain Chemistry; Depressive Disorder; Desipramine; Female; Humans; Inf | 1984 |
Urinary MHPG excretion and treatment with desipramine or amitriptyline: prediction of response, effect of treatment, and methodological hazards.
Topics: Adult; Amitriptyline; Anxiety; Depressive Disorder; Desipramine; Female; Glycols; Humans; Male; Meth | 1983 |
Desmethylimipramine and imipramine on left ventricular function and the ECG: a randomized crossover design.
Topics: Adult; Aged; Blood Pressure; Depressive Disorder; Desipramine; Double-Blind Method; Echocardiography | 1983 |
Efficacy of desipramine in mildly depressed patients: a double-blind, placebo-controlled trial [proceedings].
Topics: Adolescent; Adult; Aged; Clinical Trials as Topic; Depressive Disorder; Desipramine; Double-Blind Me | 1981 |
Relationship between plasma antidepressant levels and clinical outcome for inpatients receiving imipramine.
Topics: Adult; Aged; Antidepressive Agents; Clinical Trials as Topic; Depressive Disorder; Desipramine; Fema | 1982 |
Double-blind comparison of doxepin and desipramine in patients with primary affective disorder.
Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Depressive Disorder; Desipramine; Double-Blin | 1982 |
ECG effects of comparable plasma concentrations of desipramine and amitriptyline.
Topics: Adult; Amitriptyline; Depressive Disorder; Desipramine; Dose-Response Relationship, Drug; Electrocar | 1982 |
Predictors of response to desipramine in dysthymia.
Topics: Adult; Age Factors; Antidepressive Agents, Tricyclic; Depressive Disorder; Desipramine; Family; Fema | 1995 |
REM latency, dexamethasone suppression test, and thyroid releasing hormone stimulation test in posttraumatic stress disorder.
Topics: Adult; Biomarkers; Depressive Disorder; Desipramine; Dexamethasone; Double-Blind Method; Humans; Hyd | 1995 |
Effects of methylphenidate in HIV-related depression: a comparative trial with desipramine.
Topics: Adult; Bisexuality; Depressive Disorder; Desipramine; Dose-Response Relationship, Drug; Double-Blind | 1995 |
Differential symptom reduction in depressed cocaine abusers treated with psychotherapy and pharmacotherapy.
Topics: Adult; Cocaine; Cognitive Behavioral Therapy; Combined Modality Therapy; Comorbidity; Depressive Dis | 1995 |
Retreatment for relapse following desipramine discontinuation in dysthymia.
Topics: Adult; Aged; Depressive Disorder; Desipramine; Double-Blind Method; Drug Administration Schedule; Fe | 1995 |
Effects of exclusion criteria in depression treatment studies.
Topics: Adult; Clomipramine; Depressive Disorder; Desipramine; Double-Blind Method; Female; Humans; Male; Ps | 1994 |
Pharmacotherapy of impaired affect in recovering schizophrenic patients.
Topics: Adolescent; Adult; Ambulatory Care; Antipsychotic Agents; Anxiety Disorders; Basal Ganglia Diseases; | 1995 |
The impact of social cognitive variables on the initial level of depression and recovery.
Topics: Adult; Depressive Disorder; Desipramine; Double-Blind Method; Female; Humans; Interpersonal Relation | 1994 |
Post-stroke depression: combined treatment with imipramine or desipramine and mianserin. A controlled clinical study.
Topics: Aged; Cerebrovascular Disorders; Depressive Disorder; Desipramine; Double-Blind Method; Drug Therapy | 1994 |
Relationships of the Tridimensional Personality Questionnaire to mood and personality measures for depressed patients.
Topics: Adolescent; Adult; Affect; Bipolar Disorder; Clomipramine; Depressive Disorder; Desipramine; Female; | 1994 |
S-adenosylmethionine blood levels in major depression: changes with drug treatment.
Topics: Adult; Depressive Disorder; Desipramine; Dose-Response Relationship, Drug; Double-Blind Method; Fema | 1994 |
Desipramine for the treatment of "pure" dysthymia versus "double" depression.
Topics: Adult; Age of Onset; Ambulatory Care; Comorbidity; Depressive Disorder; Desipramine; Female; Humans; | 1994 |
Response to desipramine treatment in adolescent depression: a fixed-dose, placebo-controlled trial.
Topics: Adolescent; Ambulatory Care; Depressive Disorder; Desipramine; Dose-Response Relationship, Drug; Dou | 1994 |
Lithium and tricyclic augmentation of fluoxetine treatment for resistant major depression: a double-blind, controlled study.
Topics: Adult; Depressive Disorder; Desipramine; Dose-Response Relationship, Drug; Drug Administration Sched | 1994 |
Antisocial personality disorder as a prognostic factor for pharmacotherapy of cocaine dependence.
Topics: Adult; Amantadine; Antisocial Personality Disorder; Cocaine; Combined Modality Therapy; Comorbidity; | 1994 |
Psychotherapy and pharmacotherapy for ambulatory cocaine abusers.
Topics: Adult; Ambulatory Care; Analysis of Variance; Cocaine; Cognitive Behavioral Therapy; Combined Modali | 1994 |
Temperament predicts clomipramine and desipramine response in major depression.
Topics: Adult; Clomipramine; Comorbidity; Depressive Disorder; Desipramine; Double-Blind Method; Female; Hum | 1994 |
Sympathetic nervous system activity in major depression. Basal and desipramine-induced alterations in plasma norepinephrine kinetics.
Topics: Adult; Aged; Blood Pressure; Depression, Chemical; Depressive Disorder; Desipramine; Down-Regulation | 1994 |
Fluoxetine and desipramine in major depressive disorder.
Topics: Adult; Depressive Disorder; Desipramine; Dose-Response Relationship, Drug; Double-Blind Method; Drug | 1993 |
Changes in the frequency distribution pattern of body weight in patients with major depression.
Topics: Adult; Antidepressive Agents, Tricyclic; Body Weight; Clomipramine; Depressive Disorder; Desipramine | 1993 |
An open study of buspirone augmentation of serotonin reuptake inhibitors in refractory depression.
Topics: Adult; Ambulatory Care; Buspirone; Depressive Disorder; Desipramine; Drug Therapy, Combination; Fema | 1993 |
Side effects of methylphenidate and desipramine alone and in combination in children.
Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Child; Comorbidity; Depressive Disorder; | 1993 |
A double-blind placebo controlled study of desipramine in the treatment of ADD: III. Lack of impact of comorbidity and family history factors on clinical response.
Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Child; Child Behavior Disorders; Comorbid | 1993 |
Methylphenidate and desipramine in hospitalized children: I. Separate and combined effects on cognitive function.
Topics: Arousal; Attention; Attention Deficit Disorder with Hyperactivity; Child; Depressive Disorder; Desip | 1993 |
A placebo-controlled comparison of lithium and triiodothyronine augmentation of tricyclic antidepressants in unipolar refractory depression.
Topics: Adult; Ambulatory Care; Antidepressive Agents, Tricyclic; Depressive Disorder; Desipramine; Double-B | 1993 |
Cluster B personality disorder characteristics predict outcome in the treatment of bulimia nervosa.
Topics: Adolescent; Adult; Body Image; Borderline Personality Disorder; Bulimia; Cognitive Behavioral Therap | 1993 |
Prospective assessment of electroencephalographic sleep in remitted major depression.
Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Cerebral Cortex; Cognitive Behavioral Therap | 1993 |
Electrocardiographic changes during desipramine and clomipramine treatment in children and adolescents.
Topics: Adolescent; Antidepressive Agents, Tricyclic; Child; Clomipramine; Cross-Over Studies; Death, Sudden | 1995 |
Sertraline versus desipramine in the treatment of premenstrual syndrome: an open-label trial.
Topics: 1-Naphthylamine; Adolescent; Adult; Depressive Disorder; Desipramine; Double-Blind Method; Female; H | 1996 |
Prior antidepressant treatment does not have an impact on response to desipramine treatment in major depression.
Topics: Adult; Antidepressive Agents, Tricyclic; Depressive Disorder; Desipramine; Female; Humans; Male; Psy | 1995 |
A double-blind, placebo-controlled trial of desipramine for primary alcohol dependence stratified on the presence or absence of major depression.
Topics: Adrenergic Uptake Inhibitors; Adult; Alcoholism; Analysis of Variance; Antidepressive Agents, Tricyc | 1996 |
Clinical and biochemical effects of catecholamine depletion on antidepressant-induced remission of depression.
Topics: 1-Naphthylamine; Adrenergic Uptake Inhibitors; Antidepressive Agents; Brain; Brain Chemistry; Depres | 1996 |
The effect of a history of conduct disorder in adult major depression.
Topics: Adolescent; Adult; Alcoholism; Antidepressive Agents, Tricyclic; Child; Child Behavior Disorders; Cl | 1996 |
Six-week, double-blind, placebo-controlled study of desipramine for adult attention deficit hyperactivity disorder.
Topics: Adolescent; Adult; Age Factors; Ambulatory Care; Anxiety Disorders; Attention Deficit Disorder with | 1996 |
Maintenance therapy for chronic depression. A controlled clinical trial of desipramine.
Topics: Adult; Age of Onset; Chronic Disease; Depressive Disorder; Desipramine; Drug Administration Schedule | 1996 |
Changes in thyroid hormone levels associated with desipramine response in adolescent depression.
Topics: Adolescent; Adult; Depressive Disorder; Desipramine; Female; Humans; Male; Thyroid Hormones | 1996 |
Intimate bonds in depression.
Topics: Adolescent; Adult; Antidepressive Agents, Tricyclic; Clomipramine; Depressive Disorder; Desipramine; | 1996 |
Concurrent treatment of nonresistant major depression with desipramine and lithium: a double-blind, placebo-controlled study.
Topics: Adult; Aged; Antidepressive Agents, Tricyclic; Bipolar Disorder; Depressive Disorder; Desipramine; D | 1997 |
Antidepressant pharmacotherapy and the treatment of depression in patients with severe traumatic brain injury: a controlled, prospective study.
Topics: Accidents, Traffic; Adult; Brain Injuries; Cross-Over Studies; Depressive Disorder; Desipramine; Fem | 1996 |
Significance of monitoring plasma levels of amitriptyline, and its hydroxylated and desmethylated metabolites in prediction of the clinical outcome of depressive state.
Topics: Adult; Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Dealkylation; Depressive Disorder; Des | 1997 |
Differential pharmacological treatment response in high angry hostile and low angry hostile depressed patients: a retrospective analysis.
Topics: 1-Naphthylamine; Adult; Ambulatory Care; Analysis of Variance; Anger; Cyclohexanols; Depressive Diso | 1997 |
Does the chronological relationship between the onset of dysthymia and major depression influence subsequent response to antidepressants?
Topics: Adolescent; Adult; Aged; Ambulatory Care; Antidepressive Agents; Anxiety Disorders; Comorbidity; Dep | 1998 |
Adolescent depression: controlled desipramine treatment and atypical features.
Topics: Adolescent; Affective Symptoms; Analysis of Variance; Antidepressive Agents, Tricyclic; Chi-Square D | 1998 |
Effects of electroconvulsive therapy and desipramine on neuroendocrine responses to the clonidine challenge test.
Topics: Adrenergic alpha-Agonists; Aged; Antidepressive Agents, Tricyclic; Clonidine; Depressive Disorder; D | 1998 |
Lithium and desipramine versus desipramine alone in the treatment of severe major depression: a preliminary study.
Topics: Adult; Antidepressive Agents, Tricyclic; Depressive Disorder; Desipramine; Double-Blind Method; Drug | 1998 |
Double-blind comparison of fluoxetine and desipramine in the treatment of depressed women with advanced HIV disease: a pilot study.
Topics: Adult; Depressive Disorder; Desipramine; Double-Blind Method; Female; Fluoxetine; HIV Infections; Hu | 1999 |
Do depressed subjects who have failed both fluoxetine and a tricyclic antidepressant respond to the combination?
Topics: Adult; Antidepressive Agents, Tricyclic; Depressive Disorder; Desipramine; Drug Therapy, Combination | 1999 |
Differential response to antidepressants in women with premenstrual syndrome/premenstrual dysphoric disorder: a randomized controlled trial.
Topics: Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Comorbidity; Depressive | 1999 |
Multicenter double-blind comparison of sertraline and desipramine for concurrent obsessive-compulsive and major depressive disorders.
Topics: Adrenergic Uptake Inhibitors; Adult; Antidepressive Agents, Tricyclic; Comorbidity; Depressive Disor | 2000 |
Desipramine versus phenelzine in recurrent unipolar depression: clinical characteristics and treatment response.
Topics: Adolescent; Adult; Aged; Antidepressive Agents, Tricyclic; Depressive Disorder; Desipramine; Female; | 1997 |
Changes in lymphocyte beta-adrenergic receptors in depression and mania.
Topics: Adult; Bipolar Disorder; Clinical Trials as Topic; Cyclic AMP; Depressive Disorder; Desipramine; Dih | 1979 |
Cortisol response to intramuscular desipramine in patients with major depression and normal control subjects: a replication study.
Topics: Adolescent; Adult; Analysis of Variance; Depressive Disorder; Desipramine; Double-Blind Method; Fema | 1992 |
Functional interrelationship of serotonin and norepinephrine: cortisol response to MCPP and DMI in patients with panic disorder, patients with depression, and normal control subjects.
Topics: Adult; Depressive Disorder; Desipramine; Female; Humans; Hydrocortisone; Male; Middle Aged; Norepine | 1992 |
The impact of prior substance abuse on treatment outcome for bulimia nervosa.
Topics: Adolescent; Adult; Body Weight; Bulimia; Depressive Disorder; Desipramine; Double-Blind Method; Fema | 1992 |
Antidepressants and thyroid hormone levels.
Topics: Depressive Disorder; Desipramine; Drug Therapy, Combination; Humans; Thyroid Hormones; Thyrotropin; | 1992 |
Combined treatment with imipramine and mianserin. A controlled pilot study.
Topics: Adult; Aged; Aged, 80 and over; Depressive Disorder; Desipramine; Drug Therapy, Combination; Female; | 1992 |
Reduction of ethanol intake by pharmacologic agents--investigational problems.
Topics: Adult; Alcohol Drinking; Alcoholics Anonymous; Alcoholism; Combined Modality Therapy; Depressive Dis | 1992 |
Personality traits and response to desipramine.
Topics: Acute Disease; Adolescent; Adult; Aged; Depressive Disorder; Desipramine; Double-Blind Method; Femal | 1992 |
Response to desipramine treatment in adolescent major depression.
Topics: Adolescent; Adult; Depressive Disorder; Desipramine; Double-Blind Method; Humans; Psychiatric Status | 1991 |
Fluvoxamine versus desipramine: comparative polysomnographic effects.
Topics: Adult; Antidepressive Agents; Arousal; Delta Rhythm; Depressive Disorder; Desipramine; Double-Blind | 1991 |
Effect of fluoxetine on noradrenergic mediated growth hormone release: a double blind, placebo-controlled study.
Topics: Adult; Analysis of Variance; Depressive Disorder; Desipramine; Double-Blind Method; Female; Fluoxeti | 1991 |
A comparison of adinazolam and desipramine in the treatment of major depression.
Topics: Adult; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Benzodiazepines; Depressive Disorder; De | 1991 |
Pediatric cardiovascular effects of imipramine and desipramine.
Topics: Adolescent; Anxiety Disorders; Child; Depressive Disorder; Desipramine; Double-Blind Method; Electro | 1991 |
Acute noradrenergic effects of desipramine in depression.
Topics: Administration, Oral; Adult; Aged; Bipolar Disorder; Blood Pressure; Depressive Disorder; Desipramin | 1991 |
2-Hydroxydesipramine and desipramine plasma levels and electrocardiographic effects in depressed younger adults.
Topics: Adult; Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Depressive Disorder; Desipramine; Ele | 1991 |
Specificity of serotonin reuptake inhibitors in the treatment of obsessive-compulsive disorder. Comparison of fluvoxamine and desipramine.
Topics: Adult; Anxiety Disorders; Basal Ganglia; Depressive Disorder; Desipramine; Dopamine; Double-Blind Me | 1990 |
The role of neuropharmacologic selectivity in antidepressant action: fluvoxamine versus desipramine.
Topics: Adult; Antidepressive Agents; Depressive Disorder; Desipramine; Double-Blind Method; Female; Fluvoxa | 1990 |
Fluvoxamine in the treatment of tricyclic-resistant depression.
Topics: Adult; Antidepressive Agents; Depressive Disorder; Desipramine; Double-Blind Method; Female; Fluvoxa | 1990 |
Lithium carbonate augmentation of desipramine in refractory depression.
Topics: Depressive Disorder; Desipramine; Drug Therapy, Combination; Humans; Lithium; Lithium Carbonate; Psy | 1990 |
A double-blind comparison of fluvoxamine, desipramine and placebo in outpatients with depression.
Topics: Adult; Antidepressive Agents; Depressive Disorder; Desipramine; Double-Blind Method; Fluvoxamine; Hu | 1990 |
Plasma tryptophan to large neutral amino acid ratios in depressed and normal subjects.
Topics: Adolescent; Adult; Amino Acids; Blood-Brain Barrier; Depressive Disorder; Desipramine; Double-Blind | 1990 |
Challenging the amphetamine challenge test: report of an antidepressant treatment study.
Topics: Adult; Alprazolam; Depressive Disorder; Desipramine; Dextroamphetamine; Double-Blind Method; Female; | 1990 |
The drug-free period: a methodological issue.
Topics: Anxiety Disorders; Clinical Trials as Topic; Depressive Disorder; Desipramine; Drug Administration S | 1990 |
Antidepressant or antianxiety? A study of the efficacy of antidepressant medication.
Topics: Adult; Alprazolam; Anxiety Disorders; Clinical Trials as Topic; Depressive Disorder; Desipramine; Dr | 1990 |
A comparison of triiodothyronine and thyroxine in the potentiation of tricyclic antidepressants.
Topics: Adult; Depressive Disorder; Desipramine; Double-Blind Method; Drug Synergism; Drug Therapy, Combinat | 1990 |
Antidepressant pharmacotherapy of depression associated with multiple sclerosis.
Topics: Adult; Aged; Depressive Disorder; Desipramine; Double-Blind Method; Female; Humans; Male; Middle Age | 1990 |
Coadministration of a beta-adrenergic antagonist and a tricyclic antidepressant: a pilot study.
Topics: Depressive Disorder; Desipramine; Drug Therapy, Combination; Humans; Pilot Projects; Propranolol; Ps | 1990 |
Moclobemide (Ro 11-1163) versus desipramine in the treatment of endogenous depression.
Topics: Antidepressive Agents; Benzamides; Blood Pressure; Depressive Disorder; Desipramine; Dose-Response R | 1990 |
Fenfluramine augmentation in tricyclic-refractory depression.
Topics: Adult; Aged; Bipolar Disorder; Depressive Disorder; Desipramine; Drug Therapy, Combination; Female; | 1990 |
Selective antidepressants and cerebrospinal fluid. Lack of specificity on norepinephrine and serotonin metabolites.
Topics: Adolescent; Adult; Aged; Bipolar Disorder; Clorgyline; Depressive Disorder; Desipramine; Female; Gly | 1985 |
Reserpine augmentation of desipramine in refractory depression: clinical and neurobiological effects.
Topics: Adult; Aged; Behavior; Blood Pressure; Body Temperature; Depressive Disorder; Desipramine; Drug Resi | 1987 |
Effects of desipramine and fluvoxamine treatment on the prolactin response to tryptophan. Serotonergic function and the mechanism of antidepressant action.
Topics: Antidepressive Agents; Clinical Trials as Topic; Depressive Disorder; Desipramine; Double-Blind Meth | 1989 |
Major depression in renal dialysis patients: an open trial of antidepressant therapy.
Topics: Aged; Antidepressive Agents; Clinical Trials as Topic; Depressive Disorder; Desipramine; Humans; Kid | 1989 |
Bulimia: independence of antibulimic and antidepressant properties of desipramine.
Topics: Adult; Bulimia; Clinical Trials as Topic; Depressive Disorder; Desipramine; Dexamethasone; Double-Bl | 1989 |
Reduced REM latency predicts response to tricyclic medication in depressed outpatients.
Topics: Adolescent; Adult; Aged; Amitriptyline; Bipolar Disorder; Clinical Trials as Topic; Depressive Disor | 1989 |
Cardiovascular effects of desipramine in children.
Topics: Arrhythmias, Cardiac; Attention Deficit Disorder with Hyperactivity; Child; Clinical Trials as Topic | 1989 |
Desipramine increases circulating growth hormone in elderly depressed patients: a pilot study.
Topics: Aged; Aged, 80 and over; Amitriptyline; Clinical Trials as Topic; Depressive Disorder; Desipramine; | 1989 |
The influence of the route of administration of imipramine on imipramine and desipramine blood levels.
Topics: Administration, Oral; Adult; Aged; Clinical Trials as Topic; Depressive Disorder; Desipramine; Dose- | 1989 |
Antidepressants in 'depressed' schizophrenic inpatients. A controlled trial.
Topics: Adolescent; Adult; Amitriptyline; Benztropine; Clinical Trials as Topic; Depressive Disorder; Desipr | 1989 |
Comparison of the serum levels in primary non-agitated depressed out-patients treated with imipramine in combination with placebo, diazepam or dixyrazine.
Topics: Adult; Antipsychotic Agents; Clinical Trials as Topic; Depressive Disorder; Desipramine; Diazepam; D | 1987 |
Tricyclic antidepressants for chronic low-back pain. Mechanisms of action and predictors of response.
Topics: Adult; Back Pain; Chronic Disease; Clinical Trials as Topic; Depressive Disorder; Desipramine; Doubl | 1986 |
Antidepressant-induced weight gain: a comparison study of four medications.
Topics: Adult; Amitriptyline; Antidepressive Agents; Depressive Disorder; Desipramine; Female; Humans; Male; | 1988 |
Desipramine-yohimbine combination treatment of refractory depression. Implications for the beta-adrenergic receptor hypothesis of antidepressant action.
Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Depressive Disorder; Desipramine; Double-Blin | 1986 |
Obsessive-compulsive disorder: psychobiological approaches to diagnosis, treatment, and pathophysiology.
Topics: Adult; Brain; Clomipramine; Depressive Disorder; Desipramine; Diagnosis, Differential; Female; Human | 1987 |
Withdrawal reactions to diazepam in combined imipramine/diazepam treatment of primary nonagitated depressed outpatients.
Topics: Clinical Trials as Topic; Depressive Disorder; Desipramine; Diazepam; Double-Blind Method; Drug Ther | 1988 |
A comparison of the efficacy and safety of alprazolam and desipramine in depressed outpatients.
Topics: Adult; Alprazolam; Clinical Trials as Topic; Depressive Disorder; Desipramine; Double-Blind Method; | 1988 |
Is phosphodiesterase inhibition a new mechanism of antidepressant action? A double blind double-dummy study between rolipram and desipramine in hospitalized major and/or endogenous depressives.
Topics: Adolescent; Adult; Aged; Clinical Trials as Topic; Depressive Disorder; Desipramine; Double-Blind Me | 1988 |
Plasma 3,4-dihydroxyphenylethyleneglycol and 3-methoxy-4-hydroxyphenylethyleneglycol as indicators of central noradrenergic activity. A comparative study on control subjects and depressed patients.
Topics: Adult; Aged; Aged, 80 and over; Antidepressive Agents, Tricyclic; Brain; Clinical Trials as Topic; D | 1988 |
Antidepressants reduce whole-body norepinephrine turnover while enhancing 6-hydroxymelatonin output.
Topics: Adult; Animals; Antidepressive Agents; Bupropion; Depressive Disorder; Desipramine; Female; Humans; | 1988 |
Desipramine plasma levels and clinical response: evidence for a curvilinear relationship.
Topics: Adolescent; Adult; Aged; Clinical Trials as Topic; Depressive Disorder; Desipramine; Dose-Response R | 1987 |
Alprazolam: an antidepressant? Alprazolam, desipramine, and an alprazolam-desipramine combination in the treatment of adult depressed outpatients.
Topics: Adolescent; Adult; Alprazolam; Clinical Trials as Topic; Depressive Disorder; Desipramine; Double-Bl | 1987 |
Treating bulimia with desipramine. A double-blind, placebo-controlled study.
Topics: Adolescent; Adult; Anorexia Nervosa; Clinical Trials as Topic; Depressive Disorder; Desipramine; Fee | 1986 |
Tricyclic antidepressants in prepubertal depressed children: review of the literature.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Child; Clinical Trials as Topic; Depressive Disorde | 1986 |
Which depressions respond to placebo?
Topics: Adult; Antidepressive Agents; Azepines; Clinical Trials as Topic; Depressive Disorder; Desipramine; | 1986 |
The dexamethasone suppression test (DST) in predicting response to desipramine and amitriptyline in depressed outpatients.
Topics: Amitriptyline; Clinical Trials as Topic; Depressive Disorder; Desipramine; Dexamethasone; Humans; Hy | 1986 |
Depression in prepubertal children: dexamethasone nonsuppression predicts differential response to imipramine vs. placebo.
Topics: Child; Depressive Disorder; Desipramine; Dexamethasone; Humans; Imipramine; Placebos | 1987 |
Tricyclic antidepressants--blood level measurements and clinical outcome: an APA Task Force report. Task Force on the Use of Laboratory Tests in Psychiatry.
Topics: Antidepressive Agents, Tricyclic; Blood Chemical Analysis; Clinical Trials as Topic; Depressive Diso | 1985 |
Treatment outcome validation of DSM-III depressive subtypes. Clinical usefulness in outpatients with mild to moderate depression.
Topics: Anxiety Disorders; Bipolar Disorder; Clinical Trials as Topic; Depressive Disorder; Desipramine; Dou | 1985 |
Efficacy of lithium-tranylcypromine treatment in refractory depression.
Topics: Adult; Aged; Anti-Anxiety Agents; Benzodiazepines; Bupropion; Clinical Trials as Topic; Depressive D | 1985 |
Effect of desipramine on control of ventilation and depression scores in patients with severe chronic obstructive pulmonary disease.
Topics: Aged; Carbon Dioxide; Clinical Trials as Topic; Depressive Disorder; Desipramine; Double-Blind Metho | 1985 |
A comparison of the safety and efficacy of alprazolam and desipramine in moderately severe depression.
Topics: Adult; Alprazolam; Antidepressive Agents; Benzodiazepines; Depressive Disorder; Desipramine; Humans | 1985 |
383 other studies available for desipramine and Depression, Endogenous
| Article | Year |
|---|---|
Antidepressant-like effect induced by Cannabidiol is dependent on brain serotonin levels.
Topics: Animals; Antidepressive Agents; Brain; Cannabidiol; Depressive Disorder; Desipramine; Disease Models | 2018 |
Melancholic-Like behaviors and circadian neurobiological abnormalities in melatonin MT1 receptor knockout mice.
Topics: Animals; Antidepressive Agents, Tricyclic; Chronobiology Disorders; Circadian Rhythm; Corticosterone | 2015 |
Age-related changes in the antidepressant-like effect of desipramine and fluoxetine in the rat forced-swim test.
Topics: Aging; Animals; Antidepressive Agents; Depressive Disorder; Desipramine; Disease Models, Animal; Dos | 2016 |
Role of TrkB in the anxiolytic-like and antidepressant-like effects of vagal nerve stimulation: Comparison with desipramine.
Topics: Adrenergic Uptake Inhibitors; Animals; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Anxiet | 2016 |
Effects of antidepressants on P2X7 receptors.
Topics: Adenosine Triphosphate; Animals; Antidepressive Agents; Depressive Disorder; Desipramine; Dose-Respo | 2016 |
Desipramine improves depression-like behavior and working memory by up-regulating p-CREB in Alzheimer's disease associated mice.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Antidepressive Agents, Tricyclic; Cyclic AMP Resp | 2016 |
Influence of the selective antagonist of the NR2B subunit of the NMDA receptor, traxoprodil, on the antidepressant-like activity of desipramine, paroxetine, milnacipran, and bupropion in mice.
Topics: Analysis of Variance; Animals; Antidepressive Agents; Brain; Bupropion; Chromatography, High Pressur | 2017 |
Enduring attenuation of norepinephrine synaptic availability and augmentation of the pharmacological and behavioral effects of desipramine by repeated immobilization stress.
Topics: Amphetamine; Animals; Antidepressive Agents, Tricyclic; Anxiety; Central Nervous System Stimulants; | 2017 |
Treatment of adult ADHD and comorbid depression.
Topics: Adolescent; Adult; Antidepressive Agents, Tricyclic; Attention Deficit Disorder with Hyperactivity; | 2008 |
Animal models of depression in dopamine, serotonin, and norepinephrine transporter knockout mice: prominent effects of dopamine transporter deletions.
Topics: Animals; Antidepressive Agents; Chromosome Deletion; Depressive Disorder; Desipramine; Disease Model | 2008 |
Desipramine modulation of alpha-, gamma-synuclein, and the norepinephrine transporter in an animal model of depression.
Topics: alpha-Synuclein; Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; beta-Synuclein; Cytosk | 2009 |
Will tricyclic antidepressants make a comeback for depressed Parkinson disease patients?
Topics: Antidepressive Agents, Tricyclic; Citalopram; Depressive Disorder; Desipramine; Female; Humans; Male | 2009 |
Early prediction of the effectiveness of antidepressants: inputs from an animal model.
Topics: Amphetamine; Animals; Antidepressive Agents; Behavior, Animal; Depressive Disorder; Desipramine; Dop | 2009 |
Depression-like behaviour in rats with mononeuropathy is reduced by the CB2-selective agonist GW405833.
Topics: Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Behavior, Animal; Depressive Disor | 2009 |
Behavioral effects of four antidepressants on an ischemic rat model of emotional disturbances.
Topics: Analysis of Variance; Animals; Antidepressive Agents; Anxiety Disorders; Behavior, Animal; Brain Isc | 2009 |
gamma-Aminobutyric acid-type A receptor deficits cause hypothalamic-pituitary-adrenal axis hyperactivity and antidepressant drug sensitivity reminiscent of melancholic forms of depression.
Topics: Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents; Behavior, Animal; Corticosterone; Depr | 2010 |
A comparison between chronic exercise training and desipramine as treatments for the depression-like behavior of early-life maternal deprivation rats.
Topics: Animals; Animals, Newborn; Antidepressive Agents, Tricyclic; Depressive Disorder; Desipramine; Disea | 2010 |
Further evidence for an immediate antidepressant action of intracerebral drug administration in a model of chronic depression.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Brain; Depression; Depressive Disorder; Desipramin | 2011 |
IFN-gamma reduction by tricyclic antidepressants.
Topics: Amitriptyline; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Cyclohexa | 2010 |
Simultaneous generation of binary and normal data with specified marginal and association structures.
Topics: Algorithms; Computer Simulation; Data Interpretation, Statistical; Depressive Disorder; Desipramine; | 2012 |
Effect of long-term caffeine administration on depressive-like behavior in rats exposed to chronic unpredictable stress.
Topics: Administration, Oral; Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Body Temperature; | 2012 |
Effects of 5-HT(6) receptor blockade on the neurochemical outcome of antidepressant treatment in the frontal cortex of the rat.
Topics: Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents; Cyclohexanols; Depressive Disorder; De | 2003 |
Clinical trial with desmethylimipramine (G-35020), a new antidepressive compound.
Topics: Antidepressive Agents; Depression; Depressive Disorder; Desipramine; Imipramine | 1962 |
THE USE OF "PERTOFRAN" IN DEPRESSION: A SHORT COMMUNICATION.
Topics: Communication; Depression; Depressive Disorder; Desipramine; Humans; Imipramine | 1963 |
COMBINED ADMINISTRATION OF DESIPRAMINE AND RESERPINE OR TETRABENAZINE IN DEPRESSIVE PATIENTS.
Topics: Antidepressive Agents; Depression; Depressive Disorder; Desipramine; Humans; Imipramine; Reserpine; | 1963 |
COMPARISON BETWEEN IMIPRAMINE AND DESIPRAMINE IN NORMAL SUBJECTS AND THEIR ACTION IN DEPRESSIVE PATIENTS.
Topics: Antidepressive Agents; Depression; Depressive Disorder; Desipramine; Humans; Imipramine | 1963 |
TREATMENT OF SEVERE DEPRESSION WITH DESIPRAMINE, A METABOLITE OF IMIPRAMINE.
Topics: Adolescent; Antidepressive Agents; Brain Diseases; Depression; Depressive Disorder; Depressive Disor | 1963 |
[ENDOGENOUS DEPRESSIONS TREATED WITH PERTOFRANE].
Topics: Antidepressive Agents; Bipolar Disorder; Depressive Disorder; Desipramine; Humans; Psychotic Disorde | 1963 |
[TREATMENT OF DEPRESSED PATIENTS WITH PERTOFRANE. PRELIMINARY REPORT].
Topics: Antidepressive Agents; Depression; Depressive Disorder; Desipramine; Humans | 1963 |
DESIPRAMINE IN TREATMENT OF DEPRESSIVE ILLNESSES.
Topics: Antidepressive Agents; Depressive Disorder; Desipramine; Research | 1964 |
[RESULTS OF THE USE OF DESMETHYL-IMIPRAMINE (G-35020, PERTOFRAN) IN THE DEPRESSIVE SYNDROME].
Topics: Antidepressive Agents; Bipolar Disorder; Depressive Disorder; Desipramine; Humans; Imipramine; Menta | 1963 |
[DESMETHYLIMIPRAMINE (PERTOFRAN) IN THE TREATMENT OF DEPRESSIONS. A CLINICAL AND PSYCHODYNAMIC APPRAISAL].
Topics: Antidepressive Agents; Biomedical Research; Bipolar Disorder; Chlorpromazine; Depression; Depressive | 1963 |
[PRELIMINARY OBSERVATIONS ON THE CLINICAL USE OF A METABOLITE OF IMIPRAMINE: DESMETHYLIMIPRAMINE (G 35020)].
Topics: Antidepressive Agents; Depression; Depressive Disorder; Desipramine; Humans; Imipramine; Mental Diso | 1963 |
[DESIPRAMINE (PERTOFRAN) IN THE TREATMENT OF DEPRESSIONS WITH A PSYCHODYNAMIC ANALYSIS OF ITS THERAPEUTIC EFFECTS].
Topics: Antidepressive Agents; Biomedical Research; Bipolar Disorder; Depression; Depressive Disorder; Desip | 1964 |
[ACTION OF DESMETHYL-IMIPRAMINE (PERTOFRAN) IN DEPRESSIVE SYNDROMES].
Topics: Antidepressive Agents; Bipolar Disorder; Depressive Disorder; Desipramine; Humans; Imipramine; Neuro | 1964 |
[ON THE THERAPEUTIC EFFECTS AND SIGNIFICANCE OF A NEW ANTIDEPRESSIVE AGENT, DESMETHYLIMIPRAMINE (PERTOFRAN)].
Topics: Antidepressive Agents; Depression; Depressive Disorder; Desipramine; Drug Therapy; Humans | 1964 |
COMPARISON OF DESIPRAMINE AND IMIPRAMINE IN DEPRESSION.
Topics: Biomedical Research; Depression; Depressive Disorder; Desipramine; Drug Therapy; Imipramine; Toxicol | 1964 |
TREATMENT OF SEVERE DEPRESSION WITH DESIPRAMINE: LONG-TERM TRIAL AND FOLLOW-UP.
Topics: Constipation; Depression; Depressive Disorder; Depressive Disorder, Major; Desipramine; Drug Hyperse | 1964 |
[PROGRESS OF DEPRESSIVE DISEASES UNDER DRUG THERAPY].
Topics: Amitriptyline; Antidepressive Agents; Depression; Depressive Disorder; Desipramine; Drug Therapy; Hu | 1964 |
CLINICAL TRIAL OF DESIPRAMINE IN THE TREATMENT OF DEPRESSION.
Topics: Brain; Brain Damage, Chronic; Brain Injuries; Depression; Depressive Disorder; Desipramine; Drug The | 1965 |
CLINICAL TRIAL OF A NEW ANTIDEPRESSANT (DESIPRAMINE HYDROCHLORIDE) IN A HOSPITAL SETTING.
Topics: Antidepressive Agents; Biomedical Research; Bipolar Disorder; Depression; Depressive Disorder; Desip | 1965 |
THE DIAGNOSIS AND MANAGEMENT OF DEPRESSION.
Topics: Amitriptyline; Analgesics; Analgesics, Non-Narcotic; Antipyretics; Classification; Depression; Depre | 1965 |
THE MANAGEMENT OF DEPRESSION IN HOSPITAL. A COMPARATIVE TRIAL OF DESIPRAMINE AND IMIPRAMINE.
Topics: Biomedical Research; Depression; Depressive Disorder; Desipramine; Drug Therapy; Humans; Imipramine; | 1965 |
Desmethylimipramine (G-35020) in the treatment of depression, pilot study in a general hospital and outpatient setting.
Topics: Depression; Depressive Disorder; Desipramine; Hospitals, General; Imipramine; Outpatients; Pilot Pro | 1962 |
Preliminary investigation of desmethylimipramine (G 35020).
Topics: Depression; Depressive Disorder; Desipramine; Imipramine | 1962 |
Selectively bred Wistar-Kyoto rats: an animal model of depression and hyper-responsiveness to antidepressants.
Topics: Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Breeding; Depressive Disorder; Desipram | 2003 |
The serotonin-dopamine interaction is critical for fast-onset action of antidepressant treatment: in vivo studies in an animal model of depression.
Topics: Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents; Antidepressive Agents, Second-Generati | 2004 |
Toward a rapidly acting antidepressant: the normetanephrine and extraneuronal monoamine transporter (uptake 2) hypothesis.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic Uptake Inhibitors; Animals; Antidepressive Agent | 2004 |
Beta-arrestin-1 levels: reduced in leukocytes of patients with depression and elevated by antidepressants in rat brain.
Topics: Adult; Aged; Animals; Antidepressive Agents; Arrestins; beta-Arrestin 1; beta-Arrestins; Brain Chemi | 2004 |
Usefulness of desipramine in ICU cancer patients for acute depression.
Topics: Acute Disease; Antidepressive Agents, Tricyclic; Critical Care; Depressive Disorder; Desipramine; Hu | 2004 |
Brugada syndrome precipitated by a tricyclic antidepressant.
Topics: Adult; Antidepressive Agents, Tricyclic; Depressive Disorder; Desipramine; Electrocardiography; Huma | 2005 |
An index of local sensitivity to nonignorable drop-out in longitudinal modelling.
Topics: Animal Feed; Animals; Antidepressive Agents, Tricyclic; Antineoplastic Agents, Hormonal; Cattle; Coc | 2005 |
An index of local sensitivity to nonignorable drop-out in longitudinal modelling.
Topics: Animal Feed; Animals; Antidepressive Agents, Tricyclic; Antineoplastic Agents, Hormonal; Cattle; Coc | 2005 |
An index of local sensitivity to nonignorable drop-out in longitudinal modelling.
Topics: Animal Feed; Animals; Antidepressive Agents, Tricyclic; Antineoplastic Agents, Hormonal; Cattle; Coc | 2005 |
An index of local sensitivity to nonignorable drop-out in longitudinal modelling.
Topics: Animal Feed; Animals; Antidepressive Agents, Tricyclic; Antineoplastic Agents, Hormonal; Cattle; Coc | 2005 |
Rates of in vivo methylation of desipramine and nortriptyline.
Topics: Aged, 80 and over; Antidepressive Agents, Tricyclic; Anxiety Disorders; Depressive Disorder; Desipra | 2006 |
Brain-derived neurotrophic factor conditional knockouts show gender differences in depression-related behaviors.
Topics: Alleles; Animals; Antidepressive Agents, Tricyclic; Anxiety Disorders; Brain-Derived Neurotrophic Fa | 2007 |
Antidepressant-like activity of selective serotonin reuptake inhibitors combined with a NK1 receptor antagonist in the mouse forced swimming test.
Topics: Adrenergic Uptake Inhibitors; Analysis of Variance; Animals; Antidepressive Agents; Citalopram; Depr | 2006 |
Biphasic change in BDNF gene expression following antidepressant drug treatment explained by differential transcript regulation.
Topics: Animals; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tri | 2006 |
Chronic treatment with desipramine improves cognitive performance of rats in an attentional set-shifting test.
Topics: Adrenergic Uptake Inhibitors; Animals; Attention; Cognition; Cognition Disorders; Depressive Disorde | 2007 |
Calcineurin (protein phosphatase 2B) is involved in the mechanisms of action of antidepressants.
Topics: Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Brain-Derived Neurotrophic Factor; | 2007 |
Extinction-induced "despair" in the water maze, exploratory behavior and fear: effects of chronic antidepressant treatment.
Topics: Affect; Animals; Antidepressive Agents; Conditioning, Classical; Depressive Disorder; Desipramine; D | 2007 |
Association of graded allele-specific changes in CYP2D6 function with imipramine dose requirement in a large group of depressed patients.
Topics: Antidepressive Agents, Tricyclic; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2C19; Cytochrom | 2008 |
Enhanced norepinephrine output during long-term desipramine treatment: a possible role for the extraneuronal monoamine transporter (SLC22A3).
Topics: Adrenergic Uptake Inhibitors; Adult; Catecholamines; Depressive Disorder; Desipramine; Female; Human | 2008 |
Dopamine and depression.
Topics: Antidepressive Agents, Tricyclic; Depressive Disorder; Desipramine; Dopamine; Humans; Norepinephrine | 2007 |
Juvenile rats in the forced-swim test model the human response to antidepressant treatment for pediatric depression.
Topics: Adolescent; Age Factors; Animals; Antidepressive Agents; Child; Citalopram; Depressive Disorder; Des | 2008 |
VTA dopamine neuron bursting is altered in an animal model of depression and corrected by desipramine.
Topics: Action Potentials; Animals; Antidepressive Agents, Tricyclic; Depressive Disorder; Desipramine; Dise | 2008 |
Efficacy of imipramine in psychotic versus nonpsychotic depression.
Topics: Adult; Affective Disorders, Psychotic; Aged; Antidepressive Agents; Data Interpretation, Statistical | 2008 |
Norepinephrine transporter regulation mediates the long-term behavioral effects of the antidepressant desipramine.
Topics: alpha-Methyltyrosine; Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Binding, Competit | 2008 |
Inter-individual differences in novelty-seeking behavior in rats predict differential responses to desipramine in the forced swim test.
Topics: Animals; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Brain Chemistry | 2008 |
Adrenergic-receptor desensitization and course of clinical improvement with desipramine treatment.
Topics: Adult; Blood Pressure; Clonidine; Depressive Disorder; Desipramine; Humans; Male; Middle Aged; Recep | 1984 |
Neurochemical basis of the action of antidepressants on learned helplessness.
Topics: Animals; Brain; Depressive Disorder; Desipramine; Frontal Lobe; gamma-Aminobutyric Acid; Geniculate | 1980 |
Depression in childhood: a biopsychosocial perspective.
Topics: Adult; Child; Depressive Disorder; Desipramine; Diagnosis, Differential; Humans; Imipramine; Neurotr | 1981 |
Lorazepam and desipramine serum concentration.
Topics: Aged; Anti-Anxiety Agents; Depressive Disorder; Desipramine; Drug Interactions; Female; Humans; Lora | 1982 |
Major adverse reactions during desipramine treatment: relationship to plasma drug concentrations, concomitant antipsychotic treatment, and patient characteristics.
Topics: Adult; Age Factors; Aged; Antipsychotic Agents; Constipation; Delirium; Depressive Disorder; Desipra | 1982 |
Effect of repeated treatment with desipramine in the behavioral "despair" test in rats: antagonism by "atypical" but not "classical" neuroleptics or antiadrenergic drugs.
Topics: Adrenergic alpha-Antagonists; Animals; Antipsychotic Agents; Butyrophenones; Chlorpromazine; Clonidi | 1984 |
Antidepressant versus neuroleptic activities of sulpiride isomers on four animal models of depression.
Topics: Animals; Antidepressive Agents; Antipsychotic Agents; Apomorphine; Behavior, Animal; Body Temperatur | 1984 |
Elderly patient's confusion confounds diagnosis and treatment of depression.
Topics: Adjustment Disorders; Aged; Antipsychotic Agents; Cognition Disorders; Confusion; Dementia; Depressi | 1984 |
A double-blind study of zimelidine, a serotonin uptake inhibitor, and desipramine, a noradrenaline uptake inhibitor, in endogenous depression. II. Biochemical findings.
Topics: Adult; Aged; Animals; Antidepressive Agents; Blood Platelets; Brompheniramine; Depressive Disorder; | 1982 |
Interaction of EEG sleep, antidepressants, and affective disease.
Topics: Amitriptyline; Antidepressive Agents; Brompheniramine; Depressive Disorder; Desipramine; Electroence | 1982 |
Electroconvulsive treatment and lithium carbonate. Their effects on norepinephrine metabolism in patients with primary, major depressions.
Topics: Brompheniramine; Clorgyline; Depressive Disorder; Desipramine; Electroconvulsive Therapy; Female; Hu | 1983 |
Amoxapine elevates serum prolactin in depressed men.
Topics: Amoxapine; Bipolar Disorder; Depressive Disorder; Desipramine; Dibenzoxazepines; Humans; Male; Middl | 1983 |
Electroencephalogram and neuroendocrine parameters in pubertal and adolescent depressed children. A case report study.
Topics: Adolescent; Depressive Disorder; Desipramine; Dexamethasone; Diseases in Twins; Electroencephalograp | 1984 |
A pilot study of the mechanism of action of desipramine.
Topics: Adult; Aged; Blood Pressure; Clonidine; Depressive Disorder; Desipramine; Drug Interactions; Female; | 1981 |
Presynaptic adrenergic receptor sensitivity in depression. The effect of long-term desipramine treatment.
Topics: Adult; Aged; Blood Pressure; Brain; Clonidine; Depressive Disorder; Desipramine; Double-Blind Method | 1981 |
Neuroendocrine abnormalities in depressive illness.
Topics: Adrenocorticotropic Hormone; Adult; Aged; beta-Endorphin; beta-Lipotropin; Depressive Disorder; Desi | 1982 |
The effect of desipramine upon central adrenergic function in depressed patients.
Topics: Adult; Blood Pressure; Clonidine; Depressive Disorder; Desipramine; Female; Growth Hormone; Humans; | 1982 |
Antidepressant binding: implications for the mode of action and the biology of depression.
Topics: Animals; Binding, Competitive; Brain; Carrier Proteins; Cerebral Cortex; Depressive Disorder; Desipr | 1983 |
Relationship between plasma desipramine levels and clinical outcome for RDC major depressive inpatients.
Topics: Adult; Aged; Depressive Disorder; Desipramine; Female; Humans; Male; Middle Aged; Outcome and Proces | 1983 |
Neuroendocrine dysfunction and response to tricyclic antidepressants.
Topics: Antidepressive Agents, Tricyclic; Depressive Disorder; Desipramine; Dexamethasone; Evaluation Studie | 1984 |
Comparison of pharmacological treatment response between situational and non-situational depressions.
Topics: Amitriptyline; Depressive Disorder; Desipramine; Female; Humans; Imipramine; Life Change Events; Lit | 1984 |
Normal thyroid function in desipramine nonresponders converted to responders by the addition of L-triiodothyronine.
Topics: Adult; Depressive Disorder; Desipramine; Drug Synergism; Drug Therapy, Combination; Female; Humans; | 1984 |
The nonlinear kinetics of desipramine and 2-hydroxydesipramine in plasma.
Topics: Administration, Oral; Adolescent; Adult; Aged; Amitriptyline; Chromatography, High Pressure Liquid; | 1984 |
Use of desipramine in the medically ill.
Topics: Arrhythmias, Cardiac; Cardiovascular System; Depressive Disorder; Desipramine; Disease; Drug Adminis | 1984 |
Serum imipramine concentrations lower than plasma values.
Topics: Adult; Aged; Blood Specimen Collection; Chromatography, High Pressure Liquid; Depressive Disorder; D | 1984 |
Identifying depression secondary to lithium-induced hypothyroidism.
Topics: Bipolar Disorder; Depressive Disorder; Desipramine; Dose-Response Relationship, Drug; Drug Therapy, | 1984 |
Efficacy and feasibility of high dose tricyclic antidepressant treatment in elderly delusional depressives.
Topics: Aged; Antidepressive Agents, Tricyclic; Delusions; Depressive Disorder; Desipramine; Female; Humans; | 1984 |
Manic symptoms following addition of lithium to antidepressant treatment.
Topics: Amitriptyline; Antidepressive Agents; Bipolar Disorder; Depressive Disorder; Desipramine; Drug Thera | 1984 |
Simultaneous measurement of various antidepressants in the plasma of depressed patients by high performance liquid chromatography.
Topics: Adult; Amitriptyline; Amoxapine; Antidepressive Agents; Chromatography, High Pressure Liquid; Clomip | 1984 |
Responding for brain stimulation: stress and desmethylimipramine.
Topics: Adaptation, Psychological; Animals; Brain; Depressive Disorder; Desipramine; Dopamine; Electroshock; | 1984 |
Use of an MMPI scale to predict antidepressant response to lithium.
Topics: Adult; Amitriptyline; Bipolar Disorder; Depressive Disorder; Desipramine; Female; Humans; Lithium; M | 1983 |
Serial dexamethasone suppression test results during antidepressant therapy: relationship to diagnosis and clinical change.
Topics: Depressive Disorder; Desipramine; Dexamethasone; Female; Humans; Hydrocortisone; Male; Psychiatric S | 1983 |
Facial EMG activity levels predict treatment outcome in depression.
Topics: Amitriptyline; Antidepressive Agents; Bipolar Disorder; Depressive Disorder; Desipramine; Electromyo | 1984 |
Disputing preliminary findings on methylphenidate-desipramine responses.
Topics: Depressive Disorder; Desipramine; Humans; Methylphenidate; Nortriptyline; Probability | 1983 |
Plasma levels of imipramine and adverse effects in children.
Topics: Blood Pressure; Child; Depressive Disorder; Desipramine; Dose-Response Relationship, Drug; Electroca | 1983 |
Combined tricyclic and MAOI treatment of depressed patients.
Topics: Adult; Depressive Disorder; Desipramine; Drug Therapy, Combination; Female; Humans; Tranylcypromine | 1983 |
Changes in visual evoked potentials induced by imipramine in patients with endogenous depression.
Topics: Adult; Depressive Disorder; Desipramine; Dose-Response Relationship, Drug; Evoked Potentials, Visual | 1983 |
A trial of tricyclic antidepressant in RDC schizoaffective disorder, depressed type.
Topics: Adult; Depressive Disorder; Desipramine; Dose-Response Relationship, Drug; Female; Humans; Male; Psy | 1983 |
Drug therapy of anorexia nervosa.
Topics: Adolescent; Adult; Anorexia Nervosa; Depressive Disorder; Desipramine; Female; Humans; Imipramine | 1983 |
Subjective complaints during desipramine treatment. Relative importance of plasma drug concentrations and the severity of depression.
Topics: Attitude to Health; Depressive Disorder; Desipramine; Dizziness; Female; Hospitalization; Humans; Ma | 1984 |
Electroconvulsive therapy in pregnancy.
Topics: Depressive Disorder; Desipramine; Electroconvulsive Therapy; Female; Humans; Infant, Newborn; Pregna | 1984 |
Seminal emission induced by tricyclic antidepressant.
Topics: Anxiety Disorders; Defecation; Depressive Disorder; Desipramine; Double-Blind Method; Ejaculation; H | 1984 |
Urinary 3-methoxy-4-hydroxyphenylglycol and major affective disorders. A replication and new findings.
Topics: Adult; Bipolar Disorder; Circadian Rhythm; Depressive Disorder; Desipramine; Female; Glycols; Humans | 1984 |
What desipramine plasma levels are therapeutic?
Topics: Depressive Disorder; Desipramine; Dose-Response Relationship, Drug; Humans | 1984 |
Effects of desipramine on clinical liver function tests.
Topics: Adult; Aged; Chemical and Drug Induced Liver Injury; Depressive Disorder; Desipramine; Dose-Response | 1984 |
Elevated plasma tricyclic levels with therapeutic doses of imipramine.
Topics: Adult; Depressive Disorder; Desipramine; Electrocardiography; Female; Humans; Hydroxylation; Imipram | 1984 |
Drug-responsive symptoms in melancholia.
Topics: Delusions; Depressive Disorder; Desipramine; Female; Humans; Male; Middle Aged; Psychiatric Status R | 1984 |
Effects of chronic desipramine on plasma norepinephrine concentrations and cardiovascular parameters in elderly depressed women: a preliminary report.
Topics: Aged; Blood Pressure; Cardiovascular System; Depressive Disorder; Desipramine; Female; Heart Rate; H | 1984 |
Concentrations of desipramine in elderly women.
Topics: Aged; Depressive Disorder; Desipramine; Female; Humans; Kinetics; Long-Term Care | 1981 |
Effects of psychotropic drugs on human sperm motility.
Topics: Adult; Cell Survival; Depressive Disorder; Desipramine; Humans; In Vitro Techniques; Lithium; Lithiu | 1981 |
Does subclinical hypothyroidism predispose to tricyclic-induced rapid mood cycles?
Topics: Adult; Bipolar Disorder; Depressive Disorder; Desipramine; Female; Humans; Hypothyroidism; Lithium; | 1982 |
Abnormal anterior pituitary responsiveness to hypothalamic hormones in primary affective disorders. Effect of desipramine therapy.
Topics: Adult; Affective Disorders, Psychotic; Aged; Bipolar Disorder; Depressive Disorder; Desipramine; Fem | 1982 |
The dexamethasone suppression test in depressive illness: clinical correlates.
Topics: Depressive Disorder; Desipramine; Dexamethasone; Diagnosis, Differential; Double-Blind Method; Doxep | 1982 |
Clinical implications of 2-hydroxydesipramine plasma concentrations.
Topics: Depressive Disorder; Desipramine; Drug Evaluation; Humans; Middle Aged; Regression Analysis | 1983 |
Somatic symptoms in depression and antidepressants.
Topics: Adult; Amitriptyline; Anxiety; Autonomic Nervous System Diseases; Constipation; Depressive Disorder; | 1983 |
Cimetidine-imipramine interaction: a case report.
Topics: Adult; Cimetidine; Depressive Disorder; Desipramine; Drug Interactions; Female; Guanidines; Half-Lif | 1983 |
Desipramine-associated SIADH in an elderly woman: case report.
Topics: Aged; Depressive Disorder; Desipramine; Female; Humans; Inappropriate ADH Syndrome | 1983 |
Hypomania after desipramine withdrawal.
Topics: Adolescent; Affective Disorders, Psychotic; Bipolar Disorder; Depressive Disorder; Desipramine; Huma | 1983 |
The methylphenidate test for differentiating desipramine-responsive from nortriptyline-responsive depression.
Topics: Adolescent; Adult; Amitriptyline; Depressive Disorder; Desipramine; Emotions; Humans; Imipramine; Me | 1983 |
Desipramine and methylphenidate combination treatment for depression: case report.
Topics: Adult; Depressive Disorder; Desipramine; Drug Synergism; Drug Therapy, Combination; Humans; Male; Me | 1983 |
d-Amphetamine response and dexamethasone suppression test as predictors of treatment outcome in unipolar depression.
Topics: Adult; Depressive Disorder; Desipramine; Dexamethasone; Dextroamphetamine; Female; Humans; Hydrocort | 1983 |
Age as a predictor of treatment response in endogenous depression.
Topics: Adult; Affective Disorders, Psychotic; Age Factors; Aged; Amitriptyline; Antidepressive Agents, Tric | 1983 |
Relationship between tricyclic antidepressant plasma levels and clinical response in patients treated with desipramine or doxepin.
Topics: Adult; Depressive Disorder; Desipramine; Doxepin; Female; Humans; Male; Middle Aged; Random Allocati | 1983 |
[Comparison of the onset of the therapeutic effect of clomipramine and desipramine after oral and intravenous administration in patients with endogenous depression].
Topics: Administration, Oral; Clomipramine; Depressive Disorder; Desipramine; Humans; Infusions, Parenteral | 1983 |
Desipramine-associated hepatitis.
Topics: Adult; Chemical and Drug Induced Liver Injury; Depressive Disorder; Desipramine; Female; Humans; Liv | 1983 |
Effects of desipramine on diurnal rhythms of plasma 3-methoxy-4-hydroxyphenylglycol (MHPG) in depressed patients.
Topics: Circadian Rhythm; Depressive Disorder; Desipramine; Glycols; Humans; Methoxyhydroxyphenylglycol | 1982 |
An inverse correlation between serum levels of desmethylimipramine and melatonin-like immunoreactivity in DMI-responsive depressives.
Topics: Adolescent; Adult; Aged; Depression; Depressive Disorder; Desipramine; Female; Humans; Male; Melaton | 1981 |
Pituitary-adrenal disinhibition in depression: marker of a subtype with characteristic clinical features and response to treatment?
Topics: Adult; Amitriptyline; Clomipramine; Depressive Disorder; Desipramine; Dexamethasone; Female; Humans; | 1981 |
Plasma MHPG in depression: effects of acute and chronic desipramine treatment.
Topics: Adult; Aged; Depressive Disorder; Desipramine; Female; Glycols; Humans; Locus Coeruleus; Male; Metho | 1981 |
Depression, antidepressants, and plasma DBH.
Topics: Adult; Amitriptyline; Depressive Disorder; Desipramine; Dopamine beta-Hydroxylase; Female; Humans; M | 1981 |
Failure of chronic antidepressant treatment to alter growth hormone response to clonidine.
Topics: Amitriptyline; Clonidine; Depressive Disorder; Desipramine; Double-Blind Method; Female; Growth Horm | 1982 |
True and pseudo cholinesterases in depression.
Topics: Acetylcholinesterase; Adult; Amitriptyline; Anxiety; Butyrylcholinesterase; Cholinesterases; Depress | 1982 |
Potentiation of antidepressant effects by L-triiodothyronine in tricyclic nonresponders.
Topics: Adolescent; Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Bipolar Disorder; Depressive Dis | 1982 |
Plasma concentrations of tricyclic antidepressants in clinical practice.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Biotransformation; Depressive Disorder; Desipramine | 1982 |
Clinical conferences: Management of depression in older people.
Topics: Aged; Antidepressive Agents; Dementia; Depressive Disorder; Desipramine; Diagnosis, Differential; Do | 1982 |
Steady-state plasma imipramine levels in prepubertal depressed children.
Topics: Age Factors; Body Height; Body Weight; Child; Depressive Disorder; Desipramine; Humans; Imipramine; | 1982 |
Tricyclic antidepressants and cardiac patients with pacemakers.
Topics: Aged; Antidepressive Agents, Tricyclic; Bipolar Disorder; Depressive Disorder; Desipramine; Female; | 1982 |
The usefulness of desipramine blood level monitoring: a case report.
Topics: Adult; Computers; Depressive Disorder; Desipramine; Female; Half-Life; Humans; Personality Assessmen | 1982 |
Tricyclic antidepressant plasma levels: the state of the art and clinical prospects.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Biotransformation; Bipolar Disorder; Depressive Dis | 1982 |
TCA-induced mania: differences between switchers and nonswitchers.
Topics: Adult; Affective Disorders, Psychotic; Age Factors; Amitriptyline; Antidepressive Agents, Tricyclic; | 1982 |
Pupil studies in depressed patients: an investigation of the mechanism of action of desipramine.
Topics: Adult; Aged; Depressive Disorder; Desipramine; Drug Synergism; Female; Humans; Male; Middle Aged; Ph | 1982 |
Desipramine cardiac toxicity.
Topics: Adult; Bretylium Tosylate; Depressive Disorder; Desipramine; Heart Ventricles; Humans; Hypotension; | 1982 |
DST during drug-induced switch from depression to mania.
Topics: Bipolar Disorder; Depressive Disorder; Desipramine; Dexamethasone; Female; Humans; Hydrocortisone; L | 1982 |
Estimating steady state desipramine levels in noninstitutionalized elderly patients using single dose disposition parameters.
Topics: Aged; Depressive Disorder; Desipramine; Female; Humans; Kinetics; Male; Middle Aged; Patient Complia | 1982 |
Noninvasive measurement of cardiac ejection fraction during desipramine treatment.
Topics: Aged; Aortic Valve Stenosis; Cardiac Output; Depressive Disorder; Desipramine; Humans; Male; Stroke | 1982 |
Desipramine plasma concentration and antidepressant response.
Topics: Depressive Disorder; Desipramine; Drug Administration Schedule; Female; Humans; Male; Middle Aged; P | 1982 |
Desipramine-induced pulmonary interstitial eosinophilia.
Topics: Adult; Depressive Disorder; Desipramine; Female; Humans; Pulmonary Eosinophilia | 1982 |
Depression in children: relationship between plasma imipramine levels and response.
Topics: Age Factors; Child; Depressive Disorder; Desipramine; Female; Hospitalization; Humans; Imipramine; M | 1982 |
The relationship of therapeutic response to antidepressant plasma levels: an update.
Topics: Adult; Age Factors; Aged; Amitriptyline; Antidepressive Agents; Biological Availability; Depressive | 1982 |
Evidence for in vivo methylation of the secondary amino antidepressant desipramine to imipramine in humans.
Topics: Amitriptyline; Biotransformation; Depressive Disorder; Desipramine; Humans; Imipramine; Methylation; | 1982 |
Excessive plasma concentration of tricyclic antidepressants resulting from usual doses: a report of six cases.
Topics: Adult; Depressive Disorder; Desipramine; Dose-Response Relationship, Drug; Female; Humans; Imipramin | 1981 |
[Effect of antidepressants on the secretion of pituitary hormones in healthy subjects, neurotic depressive patients and endogenous depressive patients (author's transl)].
Topics: Adult; Anthracenes; Clomipramine; Depressive Disorder; Desipramine; Female; Growth Hormone; Humans; | 1980 |
Arrhythmia induced by a tricyclic antidepressant in a patient with undiagnosed mitral valve prolapse.
Topics: Adult; Arrhythmias, Cardiac; Depressive Disorder; Desipramine; Female; Humans; Mitral Valve Prolapse | 1981 |
The dexamethasone suppression test in the identification subtypes of depression differentially responsive to antidepressants [proceedings].
Topics: Adult; Age Factors; Aged; Amitriptyline; Clomipramine; Depressive Disorder; Desipramine; Dexamethaso | 1981 |
The clinical characteristics and treatment of atypical depression.
Topics: Adult; Anxiety Disorders; Depressive Disorder; Desipramine; Fatigue; Female; Humans; Imipramine; Mal | 1981 |
Cognitive improvement associated with tricyclic antidepressant treatment of childhood major depressive illness.
Topics: Adolescent; Amitriptyline; Antidepressive Agents, Tricyclic; Child; Cognition; Depressive Disorder; | 1981 |
The diagnosis and treatment of hidden depression.
Topics: Adolescent; Adult; Amitriptyline; Depressive Disorder; Desipramine; Diagnosis, Differential; Female; | 1981 |
Medical complications of polydipsia in nonpsychotic depression.
Topics: Acute Kidney Injury; Depressive Disorder; Desipramine; Drug Administration Schedule; Drug Therapy, C | 1994 |
New classes of antidepressants that may be lethal in combination.
Topics: Adult; Affective Disorders, Psychotic; Depressive Disorder; Desipramine; Dose-Response Relationship, | 1995 |
Resolved: cardiac arrhythmias make desipramine an unacceptable choice in children.
Topics: Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Attention Deficit Disorder with Hyperactivit | 1995 |
Lithium or desipramine augmentation of fluoxetine treatment.
Topics: Depressive Disorder; Desipramine; Dose-Response Relationship, Drug; Drug Administration Schedule; Dr | 1995 |
Comparison of TCAs and SSRIs in the treatment of major depression in hospitalized geriatric patients.
Topics: Aged; Antidepressive Agents, Tricyclic; Depressive Disorder; Desipramine; Female; Fluoxetine; Heart | 1995 |
Acute response of social functioning in dysthymic patients with desipramine.
Topics: Adult; Depressive Disorder; Desipramine; Dose-Response Relationship, Drug; Drug Administration Sched | 1995 |
Relevance of reversible inhibitors of monoamine oxidase type A and of reuptake inhibition for noradrenaline turnover.
Topics: Animals; Benzamides; Brain; Cytoplasm; Depressive Disorder; Desipramine; Humans; Kinetics; Moclobemi | 1995 |
Desipramine treatment of major depression in patients over 75 years of age.
Topics: Aged; Aged, 80 and over; Depressive Disorder; Desipramine; Dose-Response Relationship, Drug; Drug Ad | 1995 |
Atypical depression: clinical aspects and noradrenergic function.
Topics: Adult; Ambulatory Care; Depressive Disorder; Desipramine; Diagnosis, Differential; Female; Humans; H | 1995 |
Blood dyscrasias with carbamazepine and valproate: a pharmacoepidemiological study of 2,228 patients at risk.
Topics: Adolescent; Adult; Anemia; Carbamazepine; Depressive Disorder; Desipramine; Drug Therapy, Combinatio | 1995 |
Change in folate status with antidepressant treatment.
Topics: Adult; Body Weight; Cross-Sectional Studies; Depressive Disorder; Desipramine; Erythrocytes; Female; | 1994 |
Platelet 5-HT uptake sites in depression: three concurrent measures using [3H] imipramine and [3H] paroxetine.
Topics: Adult; Biomarkers; Blood Platelets; Cell Membrane; Citalopram; Depressive Disorder; Desipramine; Fem | 1993 |
On mixtures of three normal populations caused by monogenic inheritance: application to desipramine metabolism.
Topics: Adolescent; Adult; Algorithms; Depressive Disorder; Desipramine; Female; Genotype; Humans; Hydroxyla | 1994 |
Catalase, superoxide dismutase and glutathione peroxidase activity in neutrophils of sham-operated and olfactory-bulbectomised rats following chronic treatment with desipramine and lithium chloride.
Topics: Animals; Depressive Disorder; Desipramine; Disease Models, Animal; Glutathione Peroxidase; Lithium C | 1994 |
The safety of desipramine.
Topics: Adolescent; Arrhythmias, Cardiac; Cause of Death; Child; Death, Sudden, Cardiac; Depressive Disorder | 1994 |
Platelet 3H-paroxetine binding in control subjects and depressed patients: relationship to serotonin uptake and age.
Topics: Adult; Age Factors; Binding Sites; Blood Platelets; Depressive Disorder; Desipramine; Female; Fluoxe | 1994 |
Desipramine in the treatment of depressed alcoholics.
Topics: Alcoholism; Clinical Trials as Topic; Comorbidity; Depressive Disorder; Desipramine; Double-Blind Me | 1994 |
Disruption of circadian MHPG rhythmicity in major depression.
Topics: Adult; Bipolar Disorder; Circadian Rhythm; Depressive Disorder; Desipramine; Female; Humans; Male; M | 1994 |
Initiation of tricyclic treatment at full dose.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Depressive Disorder; Desipramine; Drug Administrati | 1994 |
Effects of desipramine on autonomic control of the heart.
Topics: Adolescent; Adult; Arousal; Attention Deficit Disorder with Hyperactivity; Autonomic Nervous System; | 1994 |
Personality traits during depression and after clinical recovery.
Topics: Adult; Age of Onset; Comorbidity; Depressive Disorder; Desipramine; Female; Follow-Up Studies; Human | 1994 |
Pharmacogenetics of desipramine metabolism.
Topics: Adolescent; Adult; Antidepressive Agents, Tricyclic; Chromatography, High Pressure Liquid; Depressiv | 1994 |
An interaction of sertraline and desipramine.
Topics: 1-Naphthylamine; Depressive Disorder; Desipramine; Drug Interactions; Drug Therapy, Combination; Fem | 1993 |
Effect of chronic antidepressant treatment on responses to apomorphine in selectively bred rat strains.
Topics: 1-Naphthylamine; Animals; Apomorphine; Body Temperature Regulation; Breeding; Depressive Disorder; D | 1993 |
Fluvoxamine-induced alterations in plasma concentrations of imipramine and desipramine in depressed patients.
Topics: Adult; Depressive Disorder; Desipramine; Drug Interactions; Female; Fluvoxamine; Humans; Imipramine; | 1993 |
Tolerance to fluoxetine.
Topics: 1-Naphthylamine; Adult; Depressive Disorder; Desipramine; Dose-Response Relationship, Drug; Drug The | 1993 |
Late onset tricyclic-induced agranulocytosis with an atypical course.
Topics: Agranulocytosis; Antidepressive Agents, Tricyclic; Depressive Disorder; Desipramine; Humans; Leukocy | 1993 |
Clinical features of situational and nonsituational major depression.
Topics: Adult; Depressive Disorder; Desipramine; Female; Humans; Male; Personality Disorders; Personality In | 1993 |
Desipramine does not alter plasma GABA in patients with major depression.
Topics: Adult; Aged; Biomarkers; Depressive Disorder; Desipramine; gamma-Aminobutyric Acid; Humans; Male; Mi | 1993 |
Characteristics of desipramine-refractory depression.
Topics: Adult; Depressive Disorder; Desipramine; Drug Administration Schedule; Female; Hospitalization; Huma | 1994 |
Interactions between sertraline and tricyclic antidepressants.
Topics: 1-Naphthylamine; Adult; Antidepressive Agents, Tricyclic; Depressive Disorder; Desipramine; Drug Int | 1993 |
Electrocardiographic effects of desipramine and 2-hydroxydesipramine in children, adolescents, and adults treated with desipramine.
Topics: Adolescent; Adult; Antidepressive Agents, Tricyclic; Attention Deficit Disorder with Hyperactivity; | 1993 |
A naturalistic study of 24-hour electrocardiographic recordings and echocardiographic findings in children and adolescents treated with desipramine.
Topics: Adolescent; Arrhythmias, Cardiac; Attention Deficit Disorder with Hyperactivity; Child; Child, Presc | 1993 |
Desipramine-related slate-gray skin pigmentation.
Topics: Biopsy; Depressive Disorder; Desipramine; Dose-Response Relationship, Drug; Drug Eruptions; Female; | 1993 |
Genetically determined drug-metabolizing activity and desipramine-associated cardiotoxicity: a case report.
Topics: Acetylation; Debrisoquin; Depressive Disorder; Desipramine; Electrocardiography; Family; Genetic Tes | 1993 |
The effects of antidepressants on the thyroid axis in depression.
Topics: Ambulatory Care; Antidepressive Agents; Depressive Disorder; Desipramine; Female; Fluoxetine; Humans | 1993 |
Combined fluoxetine and desipramine in resistant depression.
Topics: Depressive Disorder; Desipramine; Drug Therapy, Combination; Fluoxetine; Humans | 1993 |
Psychotropic drugs.
Topics: Adolescent; Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Child; Depressive Disorder; Desi | 1995 |
Pilocarpine for anticholinergic adverse effects associated with desipramine treatment.
Topics: Antidepressive Agents, Tricyclic; Constipation; Depressive Disorder; Desipramine; Humans; Male; Midd | 1996 |
Drug-drug interactions.
Topics: 1-Naphthylamine; Cytochrome P-450 CYP2D6; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzym | 1996 |
Treating depression in alcoholics.
Topics: Alcoholism; Antidepressive Agents, Tricyclic; Depressive Disorder; Desipramine; Double-Blind Method; | 1996 |
Law & psychiatry. Who is responsible when a patient's insurance runs out?
Topics: Adolescent; Cost Control; Depressive Disorder; Desipramine; Drug Overdose; Financing, Personal; Hosp | 1996 |
ECG changes in pediatric patients on tricyclic antidepressants, desipramine, and imipramine.
Topics: Adolescent; Alberta; Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Attention Deficit Disor | 1996 |
Biological and clinical validation of atypical depression.
Topics: Adrenergic Uptake Inhibitors; Adult; Affect; Depressive Disorder; Desipramine; Female; Humans; Hydro | 1996 |
Natural killer cell activity in major depression: a prospective study of the in vivo effects of desmethylimipramine treatment.
Topics: Adult; Depressive Disorder; Desipramine; Female; Humans; Killer Cells, Natural; Kinetics; Male; Pros | 1995 |
Fluoxetine-imipramine interaction.
Topics: Adult; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Depressive Disord | 1996 |
Steady-state plasma concentrations of imipramine and desipramine in relation to S-mephenytoin 4'-hydroxylation status in Japanese depressive patients.
Topics: Adult; Antidepressive Agents, Tricyclic; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2C19; Cy | 1996 |
SSRI or tricyclics for depression?
Topics: Adult; Depression; Depressive Disorder; Desipramine; Family Practice; Fluoxetine; Humans; Imipramine | 1996 |
Paroxetine shifts imipramine metabolism.
Topics: Adult; Antidepressive Agents, Tricyclic; Cytochrome P-450 Enzyme System; Depressive Disorder; Desipr | 1996 |
Interpersonal improvement in chronically depressed patients treated with desipramine.
Topics: Adult; Antidepressive Agents; Chronic Disease; Depressive Disorder; Desipramine; Female; Humans; Mal | 1996 |
Long-term antidepressant treatment restores clonidine's effect on growth hormone secretion in a genetic animal model of depression.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Animals; Antidepressive Agents; Ant | 1996 |
Probable nefazodone-induced mania in a patient with unreported bipolar disorder.
Topics: Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Bipolar Disorder; Depres | 1996 |
Withdrawal hypomania associated with paroxetine.
Topics: Adult; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Bipolar Disorder; | 1997 |
2-Hydroxydesipramine and desipramine plasma levels: how are they related to antidepressant response?
Topics: Adult; Antidepressive Agents, Tricyclic; Depressive Disorder; Desipramine; Female; Humans; Male; Mid | 1996 |
Relationship between plasma desipramine levels, CYP2D6 phenotype and clinical response to desipramine: a prospective study.
Topics: Adult; Antidepressive Agents, Tricyclic; Cytochrome P-450 CYP2D6; Depressive Disorder; Desipramine; | 1997 |
Selective activation of postsynaptic 5-HT1A receptors induces rapid antidepressant response.
Topics: Adult; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricy | 1997 |
Thyroid hormone levels before unsuccessful antidepressant therapy are associated with later response to T3 augmentation.
Topics: Adult; Antidepressive Agents; Depressive Disorder; Desipramine; Drug Therapy, Combination; Female; H | 1997 |
Lack of association between thyroid and pineal responses to antidepressant treatment.
Topics: Adult; Antidepressive Agents, Tricyclic; Depressive Disorder; Desipramine; Female; Humans; Male; Mel | 1996 |
Dangerous interaction with nefazodone added to fluoxetine, desipramine, venlafaxine, valproate and clonazepam combination therapy.
Topics: Adult; Antidepressive Agents; Clonazepam; Cyclohexanols; Depressive Disorder; Desipramine; Drug Ther | 1997 |
Acute and chronic antidepressant drug treatment in the rat forced swimming test model of depression.
Topics: Acute Disease; Animals; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepress | 1997 |
Sudden (un)explained death.
Topics: Antidepressive Agents, Tricyclic; Cause of Death; Child; Depressive Disorder; Desipramine; Drug Over | 1997 |
[3H] imipramine binding in brain samples from depressed suicides and controls: 5-HT uptake sites compared with sites defined by desmethylimipramine.
Topics: Adolescent; Adult; Aged; Antidepressive Agents; Binding Sites; Brain; Cause of Death; Depressive Dis | 1998 |
Anticholinergic toxic syndrome with venlafaxine-desipramine combination.
Topics: Aged; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Cholinergic Antago | 1998 |
Decrease in brain serotonin 2 receptor binding in patients with major depression following desipramine treatment: a positron emission tomography study with fluorine-18-labeled setoperone.
Topics: Antidepressive Agents, Tricyclic; Brain; Depressive Disorder; Desipramine; Down-Regulation; Fluorine | 1999 |
Lack of desipramine toxicity with citalopram.
Topics: Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Citalopram; Cytochrome P | 2000 |
Effect of subchronic antidepressant treatments on behavioral, neurochemical, and endocrine changes in the forced-swim test.
Topics: Amygdala; Animals; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive A | 2000 |
Metabolism of desipramine in Japanese psychiatric patients: the impact of CYP2D6 genotype on the hydroxylation of desipramine.
Topics: Adult; Aged; Aged, 80 and over; Antidepressive Agents, Tricyclic; Asian People; Cytochrome P-450 CYP | 2000 |
TCAs or SSRIs as initial therapy for depression?
Topics: Adult; Antidepressive Agents, Tricyclic; Costs and Cost Analysis; Depression; Depressive Disorder; D | 1999 |
Reduced brain norepinephrine and dopamine release in treatment-refractory depressive illness: evidence in support of the catecholamine hypothesis of mood disorders.
Topics: Adult; Brain; Brain Chemistry; Calorimetry, Indirect; Carbon Dioxide; Carrier Proteins; Catecholamin | 2000 |
Prolonged desipramine treatment increases the production of interleukin-10, an anti-inflammatory cytokine, in C57BL/6 mice subjected to the chronic mild stress model of depression.
Topics: Animals; Antidepressive Agents, Tricyclic; B-Lymphocytes; Depressive Disorder; Desipramine; Disease | 2001 |
Desipramine toxicity with terbinafine.
Topics: Comorbidity; Depressive Disorder; Desipramine; Drug Interactions; Humans; Male; Middle Aged; Naphtha | 2002 |
Desipramine facilitation of cocaine abstinence in an adolescent.
Topics: Adolescent; Cocaine; Depressive Disorder; Desipramine; Humans; Male; Personality Inventory; Substanc | 1992 |
Noradrenaline uptake inhibition increases melatonin secretion, a measure of noradrenergic neurotransmission, in depressed patients.
Topics: Adult; Depressive Disorder; Desipramine; Female; Humans; Male; Melatonin; Middle Aged; Norepinephrin | 1992 |
Long-term downregulation of central adrenoceptor function by desipramine treatment: a clonidine study in normal subjects.
Topics: Adult; Clonidine; Depressive Disorder; Desipramine; Down-Regulation; Growth Hormone; Growth Hormone- | 1992 |
Platelet alpha 2-adrenergic receptors in depressed patients and healthy volunteers: the effects of desipramine.
Topics: Analysis of Variance; Blood Platelets; Depressive Disorder; Desipramine; Epinephrine; Female; Humans | 1992 |
Hyperpyrexia in an adolescent on desipramine treatment.
Topics: Adolescent; Alanine Transaminase; Aspartate Aminotransferases; Creatine Kinase; Creatinine; Depressi | 1992 |
Effect of chronic antidepressant treatment with adinazolam and desipramine on melatonin output.
Topics: Adult; Anti-Anxiety Agents; Antidepressive Agents; Benzodiazepines; Depressive Disorder; Desipramine | 1992 |
Interaction between fluvoxamine and imipramine/desipramine in four patients.
Topics: Depressive Disorder; Desipramine; Drug Interactions; Female; Fluvoxamine; Humans; Imipramine; Male; | 1992 |
Exercise and antidepressant serum levels.
Topics: Adult; Amitriptyline; Depressive Disorder; Desipramine; Exercise; Female; Humans; Metabolic Clearanc | 1992 |
Growth deficits and desipramine.
Topics: Appetite; Attention Deficit Disorder with Hyperactivity; Body Weight; Child; Depressive Disorder; De | 1992 |
Tricyclic antidepressant triggers mania in patient with organic affective disorder.
Topics: Adult; Antidepressive Agents, Tricyclic; Bipolar Disorder; Brain Injuries; Depressive Disorder; Desi | 1992 |
Fluoxetine inhibits desipramine metabolism.
Topics: Attention Deficit Disorder with Hyperactivity; Depressive Disorder; Desipramine; Drug Interactions; | 1992 |
Tardive dyskinesia in the elderly patient.
Topics: Aged; Chlorpromazine; Chronic Disease; Clonazepam; Clozapine; Depressive Disorder; Desipramine; Diph | 1992 |
Plasma desipramine levels and ECG changes in depressed young adults.
Topics: Adult; Alcoholism; Depressive Disorder; Desipramine; Dose-Response Relationship, Drug; Electrocardio | 1992 |
Desipramine and the EKG.
Topics: Adolescent; Depressive Disorder; Desipramine; Dose-Response Relationship, Drug; Electrocardiography; | 1992 |
Tricyclic antidepressant-induced seizures and plasma drug concentration.
Topics: Adult; Ambulatory Care; Amitriptyline; Antidepressive Agents, Tricyclic; Depressive Disorder; Desipr | 1992 |
Adverse effects of switching from fluoxetine to desipramine.
Topics: Adult; Depressive Disorder; Desipramine; Female; Fluoxetine; Humans; Metabolic Clearance Rate; Middl | 1992 |
Developmental changes in serum concentrations of desipramine and 2-hydroxydesipramine during treatment with desipramine.
Topics: Adolescent; Adult; Age Factors; Aged; Child; Depressive Disorder; Desipramine; Dose-Response Relatio | 1992 |
Desipramine lowers tritiated para-aminoclonidine binding in platelets of depressed patients.
Topics: Adrenergic alpha-Agonists; Biomarkers; Blood Platelets; Cell Membrane; Clonidine; Depressive Disorde | 1991 |
Relationship between membrane fluidity and adrenoceptor binding in depression.
Topics: Adrenergic alpha-Agonists; Adult; Aged; Blood Platelets; Clonidine; Depressive Disorder; Desipramine | 1991 |
Effect of fluoxetine on plasma desipramine and 2-hydroxydesipramine.
Topics: Aged; Depressive Disorder; Desipramine; Drug Therapy, Combination; Female; Fluoxetine; Humans | 1992 |
Pseudodepression in hyponatremia.
Topics: Aged; Depressive Disorder; Desipramine; Humans; Hyponatremia; Imipramine; Male | 1991 |
Desipramine side-effect.
Topics: Adolescent; Depressive Disorder; Desipramine; Dose-Response Relationship, Drug; Electrocardiography; | 1991 |
Low dose tricyclic tachycardia.
Topics: Adolescent; Depressive Disorder; Desipramine; Electrocardiography, Ambulatory; Female; Humans; Nortr | 1991 |
Desipramine-induced urticaria: a clinical problem.
Topics: Adult; Ambulatory Care; Anxiety Disorders; Depressive Disorder; Desipramine; Drug Eruptions; Female; | 1991 |
Commentary on unexplained death of children on Norpramin.
Topics: Adolescent; Antidepressive Agents, Tricyclic; Child; Death, Sudden; Depressive Disorder; Desipramine | 1991 |
Response of depression to very high plasma levels of imipramine plus desipramine.
Topics: Adult; Depressive Disorder; Desipramine; Dose-Response Relationship, Drug; Drug Administration Sched | 1991 |
Refractory depression: the addition of lithium to fluoxetine or desipramine.
Topics: Adult; Depressive Disorder; Desipramine; Drug Therapy, Combination; Drug Tolerance; Female; Fluoxeti | 1991 |
Lithium carbonate augmentation of desipramine and fluoxetine in refractory depression.
Topics: Adult; Depressive Disorder; Desipramine; Drug Administration Schedule; Drug Therapy, Combination; Fe | 1991 |
Association of fluoxetine with suicidal ideation.
Topics: Depressive Disorder; Desipramine; Drug Therapy, Combination; Fluoxetine; Humans; Imipramine; Suicide | 1991 |
The cardiotoxicity of the tricyclics.
Topics: Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Attention Deficit Disorder with Hyperactivit | 1991 |
Raised serum levels of desipramine with the antiarrhythmic propafenone.
Topics: Aged; Arrhythmias, Cardiac; Depressive Disorder; Desipramine; Drug Interactions; Humans; Male; Propa | 1991 |
Sudden death in children receiving Norpramin: a review of three reported cases and commentary.
Topics: Attention Deficit Disorder with Hyperactivity; Child; Death, Sudden; Depressive Disorder; Desipramin | 1991 |
A preliminary, open study of the combination of fluoxetine and desipramine for rapid treatment of major depression.
Topics: Adult; Aged; Depressive Disorder; Desipramine; Drug Administration Schedule; Drug Therapy, Combinati | 1991 |
Use of tricyclic antidepressants in recipients of heart transplants.
Topics: Adaptation, Psychological; Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Depressive Disord | 1991 |
Symptoms of major depression: acute effect of withdrawing antidepressants.
Topics: Adult; Arousal; Chronic Disease; Depressive Disorder; Desipramine; Dose-Response Relationship, Drug; | 1991 |
Kinetic effects of desmethylimipramine treatment on platelet serotonin uptake in depressed patients: a comparison with imipramine.
Topics: Blood Platelets; Depressive Disorder; Desipramine; Humans; Imipramine; Psychiatric Status Rating Sca | 1991 |
Responses of growth hormone to desipramine in endogenous and non-endogenous depression.
Topics: Adult; Aged; Bipolar Disorder; Depressive Disorder; Desipramine; Dexamethasone; Diagnosis, Different | 1990 |
Pharmacological responsiveness of winter depression.
Topics: Adult; Antidepressive Agents; Bupropion; Depressive Disorder; Desipramine; Disorders of Excessive So | 1990 |
Elevated tricyclic antidepressant plasma concentrations associated with fluoxetine: two case reports.
Topics: Adult; Depressive Disorder; Desipramine; Drug Therapy, Combination; Female; Fluoxetine; Humans; Male | 1990 |
Does melancholia predict response in major depression?
Topics: Adult; Depressive Disorder; Desipramine; Female; Follow-Up Studies; Hospitalization; Humans; Male; M | 1990 |
Neuroendocrine challenge tests in depression: a study of growth hormone, TRH and cortisol release.
Topics: Adult; Aged; Depressive Disorder; Desipramine; Dexamethasone; Female; Growth Hormone; Humans; Hydroc | 1990 |
Alpha-2 adrenergic receptor function in post-stroke depression.
Topics: Aged; Cerebral Infarction; Depressive Disorder; Desipramine; Dominance, Cerebral; Female; Follow-Up | 1990 |
Desipramine induces cardiac beta-adrenergic sensitivity decrease in major depressed patients without relationship to therapeutic response.
Topics: Depressive Disorder; Desipramine; Down-Regulation; Heart; Heart Rate; Hospitalization; Humans; Isopr | 1990 |
Value of the DST for predicting response of patients with major depression to hospitalization and desipramine.
Topics: Adult; Depressive Disorder; Desipramine; Dexamethasone; Female; Hospitalization; Humans; Hydrocortis | 1990 |
Protracted ventricular arrhythmias occurring after abrupt tricyclic antidepressant withdrawal.
Topics: Depressive Disorder; Desipramine; Electrocardiography; Humans; Imipramine; Male; Middle Aged; Substa | 1990 |
A scale for rating tricyclic response in major depression: the TRIM.
Topics: Antidepressive Agents, Tricyclic; Depressive Disorder; Desipramine; Dose-Response Relationship, Drug | 1990 |
Effect of posture on imipramine and desipramine plasma concentrations.
Topics: Adult; Depressive Disorder; Desipramine; Female; Humans; Imipramine; Male; Middle Aged; Posture; Pro | 1990 |
Evidence for altered desipramine disposition in methadone-maintained patients treated for cocaine abuse.
Topics: Adult; Cocaine; Depressive Disorder; Desipramine; Dose-Response Relationship, Drug; Female; Humans; | 1990 |
Antidepressants in the treatment of PTSD.
Topics: Depressive Disorder; Desipramine; Humans; Stress Disorders, Post-Traumatic | 1990 |
Recurrent depression is associated with a persistent reduction in sleep-related growth hormone secretion.
Topics: Adult; Aged; Ambulatory Care; Biomarkers; Depressive Disorder; Desipramine; Electroencephalography; | 1990 |
The effect of tricyclic antidepressants on basal thyroid hormone levels in depressed patients.
Topics: Adult; Antidepressive Agents, Tricyclic; Depressive Disorder; Desipramine; Female; Humans; Male; Thy | 1990 |
"Anger attacks": possible variants of panic and major depressive disorders.
Topics: Adult; Anger; Anxiety Disorders; Clomipramine; Clonazepam; Depressive Disorder; Desipramine; Diagnos | 1990 |
Picrotoxin changes the effects of imipramine and desipramine in rats in the forced swimming test.
Topics: Animals; Depressive Disorder; Desipramine; Drug Synergism; Imipramine; Male; Motor Activity; Picroto | 1990 |
Drug-drug interactions of fluoxetine with tricyclics.
Topics: Depressive Disorder; Desipramine; Drug Synergism; Drug Therapy, Combination; Fluoxetine; Humans; Met | 1990 |
Effects of trazodone and desipramine on cardiac rate and rhythm in a patient with preexisting cardiovascular disease.
Topics: Arrhythmias, Cardiac; Cardiac Complexes, Premature; Depressive Disorder; Desipramine; Female; Heart | 1986 |
Therapeutic indications for serotonin-potentiating compounds: a hypothesis.
Topics: 5-Hydroxytryptophan; Aggression; Antidepressive Agents; Anxiety; Brain; Depressive Disorder; Desipra | 1987 |
The thyroid axis and desipramine treatment in depression.
Topics: Adult; Aged; Bipolar Disorder; Depressive Disorder; Desipramine; Humans; Male; Middle Aged; Psycholo | 1989 |
Increased 3H-clonidine binding in the platelets of patients with depressive and schizophrenic disorders.
Topics: Bipolar Disorder; Blood Platelets; Clonidine; Depressive Disorder; Desipramine; Humans; Imidazoline | 1989 |
Cardiac beta-adrenergic sensitivity in depression: relation with endogenous subtype and desipramine response.
Topics: Adjustment Disorders; Arousal; Depressive Disorder; Desipramine; Electrocardiography, Ambulatory; He | 1989 |
A study of the effects of desipramine treatment alone and in combination with L-triiodothyronine on 6-sulphatoxymelatonin excretion in depressed patients.
Topics: Adult; Aged; Depressive Disorder; Desipramine; Drug Therapy, Combination; Female; Humans; Male; Mela | 1989 |
Comparative plasma levels of doxepin and desipramine in the elderly.
Topics: Administration, Oral; Aged; Aged, 80 and over; Depressive Disorder; Desipramine; Dose-Response Relat | 1989 |
Fluoxetine and desipramine: a strategy for augmenting anti-depressant response.
Topics: Aged; Antidepressive Agents, Tricyclic; Depressive Disorder; Desipramine; Drug Therapy, Combination; | 1989 |
Plasma levels of imipramine and metabolites in 68 hospitalized children.
Topics: Adolescent; Child; Depressive Disorder; Desipramine; Female; Humans; Imipramine; Male; Psychiatric D | 1989 |
The safety of switching rapidly from tricyclic antidepressants to monoamine oxidase inhibitors.
Topics: Antidepressive Agents, Tricyclic; Depressive Disorder; Desipramine; Drug Administration Schedule; Dr | 1989 |
Serum haloperidol and desipramine concentrations and the treatment of psychotic depression: two case reports.
Topics: Adult; Depressive Disorder; Desipramine; Female; Haloperidol; Humans | 1989 |
Desipramine dose prediction based on 24-hour single-dose levels: feasibility and validity.
Topics: Adult; Circadian Rhythm; Depressive Disorder; Desipramine; Dose-Response Relationship, Drug; Humans; | 1989 |
Use of methylphenidate.
Topics: Aged; Depressive Disorder; Desipramine; Drug Therapy, Combination; Humans; Male; Methylphenidate; Re | 1989 |
Major depression in later life.
Topics: Aged; Depressive Disorder; Desipramine; Electroconvulsive Therapy; Humans; Male; Psychological Tests | 1989 |
Nonlinear kinetics of trimipramine in depressed patients.
Topics: Adult; Depressive Disorder; Desipramine; Dibenzazepines; Female; Humans; Male; Middle Aged; Trimipra | 1989 |
CSF somatostatin in affective illness and normal volunteers.
Topics: Bipolar Disorder; Carbamazepine; Depressive Disorder; Desipramine; Humans; Imipramine; Lithium; Lith | 1985 |
Super high affinity 3H-para-aminoclonidine binding to platelet adrenoceptors in depression.
Topics: Adrenergic alpha-Agonists; Adult; Blood Platelets; Clonidine; Depressive Disorder; Desipramine; Fema | 1988 |
Acute distress after switch from Norpramin to generic desipramine.
Topics: Adult; Aged; Depressive Disorder; Desipramine; Female; Humans; Male; Middle Aged; Therapeutic Equiva | 1989 |
What to do about extremely high plasma levels of tricyclics?
Topics: Adult; Depressive Disorder; Desipramine; Drug Administration Schedule; Female; Hospitalization; Huma | 1989 |
Dextroamphetamine and dexamethasone suppression test prediction of desipramine response.
Topics: Adult; Affect; Depressive Disorder; Desipramine; Dexamethasone; Dextroamphetamine; Female; Humans; H | 1989 |
Outcome with desipramine therapy in subtypes of nonpsychotic major depression.
Topics: Adolescent; Adult; Aged; Depressive Disorder; Desipramine; Dexamethasone; Female; Humans; Hydrocorti | 1985 |
Clinical studies on norepinephrine metabolism: how to interpret the numbers.
Topics: Adult; Aged; Bipolar Disorder; Depressive Disorder; Desipramine; Female; Glycols; Humans; Kinetics; | 1986 |
Antidepressants and EEG sleep: search for specificity.
Topics: Amitriptyline; Antidepressive Agents; Depressive Disorder; Desipramine; Humans; Nortriptyline; Sleep | 1987 |
Allergic skin eruption with desipramine treatment.
Topics: Adult; Depressive Disorder; Desipramine; Dose-Response Relationship, Drug; Drug Eruptions; Female; H | 1987 |
Desipramine and cutaneous reactions in pediatric outpatients.
Topics: Adolescent; Adult; Age Factors; Ambulatory Care; Anxiety Disorders; Attention Deficit Disorder with | 1988 |
Desmethylimipramine treatment increases melatonin production in humans.
Topics: Adult; Animals; Depressive Disorder; Desipramine; Female; Humans; Male; Melatonin; Middle Aged; Pine | 1986 |
Serotonin-norepinephrine receptor interactions in the brain: implications for the pharmacology and pathophysiology of affective disorders.
Topics: Adenylyl Cyclases; Animals; Antidepressive Agents; Brain; Cyclic AMP; Depressive Disorder; Desiprami | 1987 |
Neuroendocrine measures in anorexia nervosa: comparisons with primary affective disorders.
Topics: Adolescent; Adult; Anorexia Nervosa; beta-Endorphin; beta-Lipotropin; Circadian Rhythm; Clonidine; D | 1987 |
TRH test, DST, and response to desipramine in primary degenerative dementia.
Topics: Aged; Dementia; Depressive Disorder; Desipramine; Dexamethasone; Humans; Hypothalamo-Hypophyseal Sys | 1987 |
Biological markers of affective disorders and posttraumatic stress disorder: a pilot study with desipramine.
Topics: Adult; Depressive Disorder; Desipramine; Diagnosis, Differential; Humans; Male; Personality Inventor | 1987 |
Evolution of red blood cell membrane transport and plasma level of L-tyrosine and L-tryptophan in depressed treated patients according to clinical improvement.
Topics: Adult; Aged; Antidepressive Agents; Bipolar Disorder; Depressive Disorder; Desipramine; Erythrocyte | 1988 |
Stimulation of growth hormone by GHRH as compared to DMI in depressed patients.
Topics: Adult; Depressive Disorder; Desipramine; Growth Hormone; Growth Hormone-Releasing Hormone; Humans; M | 1988 |
Cerebrospinal fluid levels of amitriptyline, nortriptyline, imipramine and desmethylimipramine. Relationship to plasma levels and treatment outcome.
Topics: Amitriptyline; Bipolar Disorder; Depressive Disorder; Desipramine; Double-Blind Method; Female; Gas | 1985 |
Relapse to cocaine abuse after initiating desipramine treatment.
Topics: Adult; Bulimia; Cocaine; Depressive Disorder; Desipramine; Female; Humans; Male; Recurrence; Substan | 1988 |
Suicide upon recovery from depression. A clinical note.
Topics: Adult; Bipolar Disorder; Depressive Disorder; Desipramine; Electroconvulsive Therapy; Female; Humans | 1988 |
Personality and depression.
Topics: Adult; Depressive Disorder; Desipramine; Female; Humans; Imipramine; Male; Manuals as Topic; Persona | 1988 |
Erythrocyte electrolytes in psychiatric illness.
Topics: Adult; Bipolar Disorder; Depressive Disorder; Desipramine; Erythrocytes; Female; Humans; Male; Menta | 1988 |
Hydroxydesipramine in the elderly.
Topics: Administration, Oral; Aged; Aged, 80 and over; Depressive Disorder; Desipramine; Female; Humans; Mal | 1988 |
Fluoxetine induces elevation of desipramine level and exacerbation of geriatric nonpsychotic depression.
Topics: Adult; Depressive Disorder; Desipramine; Drug Therapy, Combination; Female; Fluoxetine; Humans | 1988 |
Desipramine and testicular swelling in two patients.
Topics: Bipolar Disorder; Depressive Disorder; Desipramine; Humans; Male; Middle Aged; Pain; Testicular Dise | 1988 |
Patterns of plasma imipramine-desipramine concentrations in patients receiving concomitant fluphenazine decanoate.
Topics: Adult; Depressive Disorder; Desipramine; Dose-Response Relationship, Drug; Drug Interactions; Drug T | 1988 |
The jitteriness syndrome in panic disorder patients treated with antidepressants.
Topics: Adult; Akathisia, Drug-Induced; Antidepressive Agents, Tricyclic; Anxiety Disorders; Depressive Diso | 1988 |
Multiple-dose pharmacokinetics of imipramine and its major active and conjugated metabolites in depressed patients.
Topics: Adult; Aged; Depressive Disorder; Desipramine; Female; Glucuronates; Humans; Imipramine; Male; Middl | 1988 |
Clonazepam-induced reduction in serum desipramine concentration.
Topics: Adult; Clonazepam; Depressive Disorder; Desipramine; Drug Therapy, Combination; Humans; Male | 1988 |
Sequence of drug administration in lithium augmentation: a case study.
Topics: Adult; Depressive Disorder; Desipramine; Drug Administration Schedule; Drug Therapy, Combination; Hu | 1988 |
Anorgasmia associated with desipramine.
Topics: Adult; Depressive Disorder; Desipramine; Female; Humans; Orgasm; Sexual Dysfunctions, Psychological | 1988 |
Behavioural and neuropharmacological properties of the dibenzazepines, desipramine and lofepramine: studies on the olfactory bulbectomized rat model of depression.
Topics: Animals; Arousal; Avoidance Learning; Behavior, Animal; Clonidine; Depressive Disorder; Desipramine; | 1988 |
Alprazolam does not inhibit the metabolism of nortriptyline in depressed patients or inhibit the metabolism of desipramine in human liver microsomes.
Topics: Adult; Alprazolam; Depressive Disorder; Desipramine; Drug Interactions; Female; Humans; Hydroxylatio | 1988 |
Anhedonic ejaculation with desipramine.
Topics: Attention; Attention Deficit Disorder with Hyperactivity; Depressive Disorder; Desipramine; Ejaculat | 1988 |
Antidepressant activity of 2-hydroxydesipramine.
Topics: Adult; Aged; Antidepressive Agents, Tricyclic; Depressive Disorder; Desipramine; Female; Humans; Mal | 1988 |
Transient mood elevation associated with antidepressant drug decrease.
Topics: Bipolar Disorder; Depressive Disorder; Desipramine; Emotions; Female; Humans; Middle Aged; Substance | 1987 |
Patterns of melatonin rhythms in depression.
Topics: Adult; Circadian Rhythm; Depression; Depressive Disorder; Desipramine; Female; Humans; Isoproterenol | 1986 |
Use of tricyclic antidepressants in a patient with malignant hyperthermia.
Topics: Adult; Antidepressive Agents, Tricyclic; Depressive Disorder; Desipramine; Female; Humans; Malignant | 1987 |
Nonlinear desipramine kinetics: prevalence and importance.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Depressive Disorder; Desipramine; Dose-Response Relation | 1987 |
Testicular swelling associated with desipramine.
Topics: Adult; Angioedema; Depressive Disorder; Desipramine; Edema; Humans; Male; Middle Aged; Testicular Di | 1987 |
Rapid desipramine dose adjustment using 24-hour levels.
Topics: Adult; Aged; Depressive Disorder; Desipramine; Humans; Kinetics; Middle Aged; Time Factors | 1987 |
Lack of weight gain under desipramine.
Topics: Adult; Body Weight; Depressive Disorder; Desipramine; Female; Humans; Male; Middle Aged | 1987 |
Desipramine and phenytoin: a potential drug interaction of therapeutic relevance.
Topics: Adult; Depressive Disorder; Desipramine; Drug Interactions; Epilepsy; Female; Humans; Male; Phenytoi | 1987 |
Imipramine blood levels and clinical outcome.
Topics: Adult; Aged; Aging; Depressive Disorder; Desipramine; Female; Humans; Imipramine; Male; Middle Aged; | 1987 |
Treating depressions of bereavement with antidepressants. A pilot study.
Topics: Adult; Aged; Bereavement; Death; Depressive Disorder; Desipramine; Female; Humans; Male; Middle Aged | 1987 |
Response of tardive and L-dopa-induced dyskinesias to antidepressants.
Topics: Aged; Antidepressive Agents; Depressive Disorder; Desipramine; Dyskinesia, Drug-Induced; Humans; Lev | 1987 |
Desipramine and weight gain.
Topics: Body Weight; Depressive Disorder; Desipramine; Humans | 1987 |
Possible nonlinear pharmacokinetics of desipramine after once daily dosing.
Topics: Adult; Depressive Disorder; Desipramine; Female; Humans; Kinetics; Liver; Male; Middle Aged | 1986 |
Alprazolam and desipramine in moderately severe depression.
Topics: Alprazolam; Benzodiazepines; Depressive Disorder; Desipramine; Humans | 1986 |
Imipramine in adolescent major depression: plasma level and clinical response.
Topics: Adolescent; Age Factors; Anxiety, Separation; Child; Depressive Disorder; Desipramine; Electrocardio | 1986 |
Neuroleptic dose and desipramine concentrations during combined treatment of unipolar delusional depression.
Topics: Administration, Oral; Adult; Aged; Delusions; Depressive Disorder; Desipramine; Drug Administration | 1986 |
The dexamethasone suppression test in bulimia before and after successful treatment with desipramine.
Topics: Adolescent; Adult; Body Weight; Bulimia; Depressive Disorder; Desipramine; Dexamethasone; Female; Hu | 1986 |
Electrocardiogram changes and therapeutic desipramine and 2-hydroxy-desipramine concentrations in elderly depressives.
Topics: Aged; Depressive Disorder; Desipramine; Electrocardiography; Female; Humans; Male; Middle Aged; Time | 1986 |
Desipramine and 2-hydroxydesipramine in human breast milk and the nursing infant's serum.
Topics: Adult; Breast Feeding; Depressive Disorder; Desipramine; Female; Humans; Infant, Newborn; Kinetics; | 1986 |
Desipramine plasma concentration and therapeutic response in elderly depressives: a naturalistic pilot study.
Topics: Aged; Aged, 80 and over; Depressive Disorder; Desipramine; Dexamethasone; Female; Humans; Hydrocorti | 1986 |
The desipramine cortisol test--a selective noradrenergic challenge (relationship to other cortisol tests in depressives and normals).
Topics: Adult; Depressive Disorder; Desipramine; Female; Humans; Hydrocortisone; Male; Middle Aged | 1986 |
Behavioral depression following clonidine withdrawal: a new animal model of long-lasting depression?
Topics: Animals; Clonidine; Depressive Disorder; Desipramine; Disease Models, Animal; Rats; Substance Withdr | 1986 |
The effect of desipramine on body weight in depression.
Topics: Adult; Body Weight; Depressive Disorder; Desipramine; Dose-Response Relationship, Drug; Female; Huma | 1987 |
Imipramine and tinnitus.
Topics: Adult; Depressive Disorder; Desipramine; Female; Humans; Imipramine; Male; Middle Aged; Retrospectiv | 1987 |
The cortisol response to desipramine in endogenous depressives and normal controls: preliminary findings.
Topics: Adult; Depressive Disorder; Desipramine; Female; Humans; Hydrocortisone; Injections, Intramuscular; | 1985 |
The dexamethasone suppression and TRH stimulation tests in the initial phase of depression treatment.
Topics: Adult; Aged; Depressive Disorder; Desipramine; Dexamethasone; Female; Humans; Hydrocortisone; Male; | 1985 |
The effect of clorgyline on noradrenergic function.
Topics: Adult; Aged; Blood Pressure; Clorgyline; Depressive Disorder; Desipramine; Female; Heart Rate; Human | 1985 |
Abnormal anterior pituitary responsiveness to hypothalamic hormones in depression: neurophysiological correlates and psychopharmacological effects.
Topics: Adult; Aged; Bipolar Disorder; Clomipramine; Depressive Disorder; Desipramine; Female; Gonadotropin- | 1985 |
Are antidepressant trials too short? A case report.
Topics: Depressive Disorder; Desipramine; Female; Humans; Middle Aged; Time Factors | 1986 |
Painful postcoital testicular retraction linked with desipramine.
Topics: Adult; Coitus; Depressive Disorder; Desipramine; Humans; Male; Muscle Contraction; Pain; Spasm; Test | 1986 |
Focal cognitive deficits accentuated by depression.
Topics: Adult; Brain Diseases; Brain Injuries; Cognition Disorders; Depressive Disorder; Desipramine; Humans | 1985 |
Trazodone-induced mania following desipramine-induced mania in major depressive disorders.
Topics: Aged; Bipolar Disorder; Depressive Disorder; Desipramine; Female; Humans; Male; Middle Aged; Piperaz | 1985 |
Nonlinear desipramine pharmacokinetics: a case study.
Topics: Aged; Depressive Disorder; Desipramine; Humans; Kinetics; Male | 1985 |
Tolerance to therapeutic effects of antidepressants.
Topics: Adult; Aged; Amitriptyline; Antidepressive Agents; Chronic Disease; Depressive Disorder; Desipramine | 1985 |
Desipramine and 2-hydroxydesipramine plasma levels in endogenous depressed patients. Lack of correlation with therapeutic response.
Topics: Adolescent; Adult; Depressive Disorder; Desipramine; Female; Humans; Male; Middle Aged; Psychiatric | 1985 |
Desipramine plasma levels and response in elderly melancholic patients.
Topics: Adult; Age Factors; Aged; Depressive Disorder; Desipramine; Female; Humans; Male; Middle Aged | 1985 |
Idiosyncratic pharmacokinetics complicating treatment of major depression in an elderly woman.
Topics: Depressive Disorder; Desipramine; Diphenhydramine; Female; Half-Life; Hospitalization; Humans; Kinet | 1985 |
Effects of antidepressant drugs on a quickly-learned conditioned-suppression response in mice.
Topics: Acridines; Amitriptyline; Animals; Antidepressive Agents; Depressive Disorder; Desipramine; Diphenhy | 1985 |
Nocturnal serum melatonin in major depressive disorder before and after desmethylimipramine treatment.
Topics: Adult; Circadian Rhythm; Depressive Disorder; Desipramine; Humans; Male; Melatonin | 1985 |
Biochemical and diagnostic classification and serum drug levels: relation to antidepressive effect of imipramine.
Topics: Adjustment Disorders; Depressive Disorder; Desipramine; Female; Humans; Imipramine; Male; Middle Age | 1985 |
Acute response to methylphenidate as a predictor of outcome of treatment with TCAs in the elderly.
Topics: Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Depressive Disorder; Desipramine; Emotions; F | 1985 |
Tricyclic blood levels.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Depressive Disorder; Desipramine; Humans | 1985 |
The effect of desipramine upon melatonin and cortisol secretion in depressed and normal subjects.
Topics: Adolescent; Adult; Depressive Disorder; Desipramine; Female; Humans; Hydrocortisone; Male; Melatonin | 1985 |
Growth hormone release after desipramine in depressive illness.
Topics: Adult; Aged; Bipolar Disorder; Depressive Disorder; Desipramine; Female; Growth Hormone; Humans; Mal | 1985 |