desipramine has been researched along with Dementia Praecox in 35 studies
Desipramine: A tricyclic dibenzazepine compound that potentiates neurotransmission. Desipramine selectively blocks reuptake of norepinephrine from the neural synapse, and also appears to impair serotonin transport. This compound also possesses minor anticholinergic activity, through its affinity to muscarinic receptors.
desipramine : A dibenzoazepine consisting of 10,11-dihydro-5H-dibenzo[b,f]azepine substituted on nitrogen with a 3-(methylamino)propyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Among the more important recent discoveries are the efficacy of the tricyclic antidepressants for panic disorder and agoraphobia with panic attacks; the use of the monoamine oxidase inhibitors for the above disorders and for atypical depression and hysteroid dysphoria; the use of propranolol for anxiety disorders and for uncontrollable violent outbursts; the antianxiety and antipanic effects of clonidine; and the usefulness of lithium in treating schizophrenia and schizoaffective disorder and for emotionally unstable character disorders." | 4.76 | Newer uses for older psychotropic medications. ( Liebowitz, MR, 1982) |
| " To develop an animal model for the negative symptoms of schizophrenia, in particular, the depressive symptoms, the effect of phencyclidine (PCP) on immobility in the forced swimming test was investigated in mice, since PCP produces negative symptoms-like behavioral changes in humans." | 3.69 | [Behavioral assessment of neuroleptics (3)--Schizophrenia negative symptoms-like model induced by PCP]. ( Nabeshima, T; Noda, Y, 1996) |
| "We have previously found that repeated phencyclidine (PCP) treatment enhances the immobility induced by forced swimming and suggested that this behavioral change could be used as a model of the negative symptoms, particularly depression, of schizophrenia." | 3.69 | Effects of antidepressants on phencyclidine-induced enhancement of immobility in a forced swimming test in mice. ( Furukawa, H; Mamiya, T; Nabeshima, T; Noda, Y, 1997) |
| "Desipramine 50 mg/day was coadministered for 1 week, and blood samplings and clinical ratings were performed before and after the coadministration." | 2.68 | No interaction between desipramine and bromperidol. ( Inoue, Y; Ishida, M; Kaneko, S; Kondo, T; Mihara, K; Otani, K; Suzuki, A; Yasui, N, 1996) |
| "Ziprasidone was tested as a positive control." | 1.33 | Effects of acute treatment with antidepressant drugs on sensorimotor gating deficits in rats. ( Andersen, MP; Hogg, S; Pouzet, B, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 27 (77.14) | 18.7374 |
| 1990's | 5 (14.29) | 18.2507 |
| 2000's | 2 (5.71) | 29.6817 |
| 2010's | 1 (2.86) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Preskorn, SH | 1 |
| Scornaiencki, R | 1 |
| Cantrup, R | 1 |
| Rushlow, WJ | 1 |
| Rajakumar, N | 1 |
| ALNAES, R | 1 |
| KRISTIANSEN, J | 1 |
| PALESTINE, ML | 1 |
| Pouzet, B | 1 |
| Andersen, MP | 1 |
| Hogg, S | 1 |
| Liebowitz, MR | 1 |
| Enna, SJ | 1 |
| Hogarty, GE | 1 |
| McEvoy, JP | 1 |
| Ulrich, RF | 1 |
| DiBarry, AL | 1 |
| Bartone, P | 1 |
| Cooley, S | 1 |
| Hammill, K | 1 |
| Carter, M | 1 |
| Munetz, MR | 1 |
| Perel, J | 1 |
| Noda, Y | 2 |
| Nabeshima, T | 2 |
| Suzuki, A | 1 |
| Otani, K | 1 |
| Ishida, M | 1 |
| Yasui, N | 1 |
| Kondo, T | 1 |
| Mihara, K | 1 |
| Kaneko, S | 1 |
| Inoue, Y | 1 |
| Mamiya, T | 1 |
| Furukawa, H | 1 |
| Perel, JM | 1 |
| Mendlewicz, J | 1 |
| Shostak, M | 1 |
| Kantor, SJ | 1 |
| Glassman, AH | 1 |
| Gram, LF | 1 |
| Ziedonis, D | 1 |
| Richardson, T | 1 |
| Lee, E | 1 |
| Petrakis, I | 1 |
| Kosten, T | 1 |
| Pandey, GN | 1 |
| Janicak, PG | 1 |
| Javaid, JI | 2 |
| Davis, JM | 2 |
| Kramer, MS | 1 |
| Vogel, WH | 1 |
| DiJohnson, C | 1 |
| Dewey, DA | 1 |
| Sheves, P | 1 |
| Cavicchia, S | 1 |
| Little, P | 1 |
| Schmidt, R | 1 |
| Kimes, I | 1 |
| Sharma, R | 1 |
| Janicak, P | 1 |
| Faull, K | 1 |
| Comaty, J | 1 |
| Grahame-Smith, DG | 1 |
| Geaney, DP | 1 |
| Schachter, M | 1 |
| Elliott, JM | 1 |
| Esche, I | 1 |
| Joffe, RT | 1 |
| Blank, DW | 1 |
| Siris, SG | 1 |
| Adan, F | 1 |
| Lee, A | 1 |
| Cooper, TB | 1 |
| Mandeli, J | 1 |
| Casey, E | 1 |
| Prange, AJ | 1 |
| Donlon, PT | 1 |
| Blacker, KH | 1 |
| el-Yousef, MK | 1 |
| Manier, DH | 1 |
| Zingales, I | 1 |
| Zung, WW | 1 |
| Narasimhachari, N | 1 |
| Lin, RL | 1 |
| Fonlupt, V | 1 |
| Gauthier-Lafaye, P | 1 |
| Sichel, JP | 1 |
| Kammerer, M | 1 |
| Wartel, R | 1 |
| Gurfein, L | 1 |
| Weil, J | 1 |
| Wysoki, V | 1 |
| Gelb, F | 1 |
| Arbitman, R | 1 |
| Yurtcu, A | 1 |
| Lehmann, HE | 1 |
| Sterlin, C | 1 |
| Ban, TA | 1 |
| Jarrold, L | 1 |
| Fischer, E | 1 |
| Spatz, H | 1 |
| Saavedra, JM | 1 |
| Reggiani, H | 1 |
| Miró, AH | 1 |
| Heller, B | 1 |
| Yamauchi, I | 1 |
| Huber, G | 1 |
| Wolpowitz, B | 1 |
| Roux, JT | 1 |
| Battegay, R | 1 |
| Poeldinger, W | 1 |
| Giudicelli, S | 1 |
5 reviews available for desipramine and Dementia Praecox
| Article | Year |
|---|---|
Clinical psychopharmacology and medical malpractice: the four Ds.
Topics: Adult; Antidepressive Agents; Antipsychotic Agents; Attention Deficit Disorder with Hyperactivity; C | 2014 |
Newer uses for older psychotropic medications.
Topics: Adrenergic beta-Antagonists; Agoraphobia; Anxiety Disorders; Bipolar Disorder; Clonidine; Depressive | 1982 |
Human platelet 5-hydroxytryptamine receptors: binding of [3H]-lysergic acid diethylamide (LSD). Effects of chronic neuroleptic and antidepressant drug administration.
Topics: Antidepressive Agents; Antipsychotic Agents; Cell Membrane; Desipramine; Humans; Lysergic Acid Dieth | 1988 |
Psychotropic drugs and the thyroid axis: a review of interactions.
Topics: Animals; Body Temperature; Brain; Chlorpromazine; Depressive Disorder; Desipramine; Drug Interaction | 1985 |
The pharmacology of disordered sleep: a laboratory approach.
Topics: Amitriptyline; Anxiety; Arousal; Barbiturates; Brain; Cerebral Cortex; Depression; Desipramine; Huma | 1970 |
5 trials available for desipramine and Dementia Praecox
| Article | Year |
|---|---|
Pharmacotherapy of impaired affect in recovering schizophrenic patients.
Topics: Adolescent; Adult; Ambulatory Care; Antipsychotic Agents; Anxiety Disorders; Basal Ganglia Diseases; | 1995 |
No interaction between desipramine and bromperidol.
Topics: Adult; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Chromatography, High Pressure Liquid; | 1996 |
Antidepressants in 'depressed' schizophrenic inpatients. A controlled trial.
Topics: Adolescent; Adult; Amitriptyline; Benztropine; Clinical Trials as Topic; Depressive Disorder; Desipr | 1989 |
[Clinical experimentation with desipramine with statistical control].
Topics: Adult; Aged; Anorexia Nervosa; Barbiturates; Bipolar Disorder; Chlordiazepoxide; Chlorpromazine; Cli | 1968 |
Protrptyline in the treatment of chronic schizophrenic patients.
Topics: Adolescent; Adult; Clinical Trials as Topic; Desipramine; Dibenzocycloheptenes; Female; Humans; Male | 1970 |
25 other studies available for desipramine and Dementia Praecox
| Article | Year |
|---|---|
Prefrontal cortical D1 dopamine receptors modulate subcortical D2 dopamine receptor-mediated stress responsiveness.
Topics: Animals; Behavior, Animal; Benzazepines; Desipramine; Dopamine; Dopamine Agonists; Dopamine Antagoni | 2009 |
[DESMETHYLIMIPRAMINE (PERTOFRAN) IN THE TREATMENT OF DEPRESSIONS. A CLINICAL AND PSYCHODYNAMIC APPRAISAL].
Topics: Antidepressive Agents; Biomedical Research; Bipolar Disorder; Chlorpromazine; Depression; Depressive | 1963 |
DESIPRAMINE IN THE TREATMENT OF LONG STANDING PSYCHOTIC DISORDERS.
Topics: Depression; Desipramine; Drug Therapy; Hypnotics and Sedatives; Phenothiazines; Psychotic Disorders; | 1965 |
Effects of acute treatment with antidepressant drugs on sensorimotor gating deficits in rats.
Topics: Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents; Antipsychotic Agents; Bupropion; Cital | 2005 |
Brain serotonin receptors and neuropsychiatric disorders.
Topics: Animals; Brain; Desipramine; Fluoxetine; Humans; Imipramine; Kinetics; Lysergic Acid Diethylamide; M | 1981 |
[Behavioral assessment of neuroleptics (3)--Schizophrenia negative symptoms-like model induced by PCP].
Topics: Animals; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Clozapine; Desipramine; Disease Mod | 1996 |
Effects of antidepressants on phencyclidine-induced enhancement of immobility in a forced swimming test in mice.
Topics: Animals; Antidepressive Agents; Depression; Desipramine; Hallucinogens; Hydroxyindoleacetic Acid; Ma | 1997 |
Plasma levels of imipramine in depression. Environmental and genetic factors.
Topics: Adult; Binding Sites; Biological Availability; Depression; Desipramine; Humans; Hydroxylation; Imipr | 1976 |
Effects of perphenazine on imipramine metabolism in man.
Topics: Adult; Desipramine; Drug Interactions; Female; Glucuronates; Humans; Imipramine; Male; Middle Aged; | 1975 |
Adjunctive desipramine in the treatment of cocaine abusing schizophrenics.
Topics: Adult; Cocaine; Desipramine; Female; Humans; Male; Schizophrenia; Schizophrenic Psychology; Substanc | 1992 |
Increased 3H-clonidine binding in the platelets of patients with depressive and schizophrenic disorders.
Topics: Bipolar Disorder; Blood Platelets; Clonidine; Depressive Disorder; Desipramine; Humans; Imidazoline | 1989 |
Plasma and CSF HVA before and after pharmacological treatment.
Topics: Adult; Brain; Desipramine; Female; Homovanillic Acid; Humans; Lithium; Male; Psychiatric Status Rati | 1989 |
Erythrocyte electrolytes in psychiatric illness.
Topics: Adult; Bipolar Disorder; Depressive Disorder; Desipramine; Erythrocytes; Female; Humans; Male; Menta | 1988 |
Patterns of plasma imipramine-desipramine concentrations in patients receiving concomitant fluphenazine decanoate.
Topics: Adult; Depressive Disorder; Desipramine; Dose-Response Relationship, Drug; Drug Interactions; Drug T | 1988 |
Stages of schizophrenic decompensation and reintegration.
Topics: Adult; Affect; Aggression; Antipsychotic Agents; Anxiety; Depression; Desipramine; Fear; Female; Flu | 1973 |
Letter: Tricyclic antidepressants and phenothiazines.
Topics: Desipramine; Drug Interactions; Drug Therapy, Combination; Humans; Phenothiazines; Schizophrenia | 1974 |
Systematic identification of psychotropic drugs by thin layer chromatography. II.
Topics: Amitriptyline; Chlorpromazine; Chlorprothixene; Chromatography, Thin Layer; Desipramine; Female; Hum | 1968 |
A possible mechanism for the antischizophrenic action of chlorpromazine: inhibition of the formation of dimethyltryptamine by chlorpromazine metabolites.
Topics: Animals; Carbon Radioisotopes; Chlorpromazine; Chromatography, Gas; Chromatography, Thin Layer; Desi | 1974 |
[The combination chlomipramine-desipramine in various forms of developing schizophrenia].
Topics: Adult; Desipramine; Dibenzazepines; Drug Therapy, Combination; Humans; Infusions, Parenteral; Propyl | 1973 |
Urinary elimination of phenethylamine.
Topics: Chromatography, Gas; Depression; Desipramine; Dibenzazepines; Epilepsy, Temporal Lobe; Humans; Menta | 1972 |
[The effects of psychotropic drugs upon the photically driven theta response of EEG].
Topics: Desipramine; Electrocardiography; Humans; Light; Reserpine; Schizophrenia; Spiro Compounds; Tranquil | 1971 |
[Cenesthetic schizophrenia as a significant type in schizophrenic diseases].
Topics: Adult; Affective Symptoms; Amitriptyline; Brain Stem; Desipramine; Diagnosis, Differential; Electroe | 1971 |
[Parenteral treatment of depressive diseases].
Topics: Antidepressive Agents; Bipolar Disorder; Dementia; Depression; Depressive Disorder, Major; Desiprami | 1970 |
[Comparative clinical experiences with dibenzazepine and dibenzodiazepine derivatives].
Topics: Antidepressive Agents; Depression; Desipramine; Dibenzazepines; Humans; Imipramine; Middle Aged; Sch | 1967 |
[Apropos of 60 patients treated with Pertofran].
Topics: Adult; Depression; Desipramine; Female; Humans; Male; Middle Aged; Schizophrenia | 1968 |