Page last updated: 2024-10-25

desipramine and Decerebrate Posturing

desipramine has been researched along with Decerebrate Posturing in 18 studies

Desipramine: A tricyclic dibenzazepine compound that potentiates neurotransmission. Desipramine selectively blocks reuptake of norepinephrine from the neural synapse, and also appears to impair serotonin transport. This compound also possesses minor anticholinergic activity, through its affinity to muscarinic receptors.
desipramine : A dibenzoazepine consisting of 10,11-dihydro-5H-dibenzo[b,f]azepine substituted on nitrogen with a 3-(methylamino)propyl group.

Research Excerpts

ExcerptRelevanceReference
"Continuous infusions of 5-hydroxytryptamine (5-HT) inhibit the tachycardiac responses to preganglionic (C7-T1) sympathetic stimulation in pithed rats pretreated with desipramine."3.72Pharmacological profile of the 5-HT-induced inhibition of cardioaccelerator sympathetic outflow in pithed rats: correlation with 5-HT1 and putative 5-ht5A/5B receptors. ( Arulmani, U; Centurión, D; Sánchez-Lopez, A; Saxena, PR; Vázquez, E; Villalón, CM, 2003)
"treatment with desipramine (50 micrograms/kg)."1.295-hydroxytryptamine inhibits pressor responses to preganglionic sympathetic nerve stimulation in pithed rats. ( Castillo, C; Contreras, J; López-Muñoz, FJ; Perusquía, M; Ramŕiez-San Juan, E; Terrón, JA; Villalón, CM, 1995)
"It is likely that these drugs reduce decerebrate rigidity by inhibiting fusimotor activity."1.25A comparison of the actions of some drugs on decerebrate rigidity, muscle spindle activity and alpha-adrenoceptors. ( Maxwell, DR; Sumpter, EA, 1974)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-199013 (72.22)18.7374
1990's3 (16.67)18.2507
2000's1 (5.56)29.6817
2010's1 (5.56)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Vacher, B1
Funes, P1
Chopin, P1
Cussac, D1
Heusler, P1
Tourette, A1
Marien, M1
Sánchez-Lopez, A2
Centurión, D2
Vázquez, E1
Arulmani, U1
Saxena, PR1
Villalón, CM3
Contreras, J1
Ramŕiez-San Juan, E1
Castillo, C1
Perusquía, M1
López-Muñoz, FJ1
Terrón, JA1
del Mar Fernández, M1
Morán, A1
Neal, H2
Bradley, PB2
Key, BJ1
Krzywosinski, L1
Bymaster, FB1
Perry, KW1
Fuller, RW1
Wong, DT1
Rawlow, A1
King, RG1
Majewski, H2
Midol-Monnet, M1
Heimburger, M1
Davy, M1
Beslot, F1
Cohen, Y1
Szabo, B1
Hedler, L2
Starke, K2
Göthert, M1
Schlicker, E1
Kollecker, P1
Ensinger, H1
Finberg, JP1
Kopin, IJ1
Sinclair, JG1
Sastry, BS1
Maxwell, DR2
Sumpter, EA2

Other Studies

18 other studies available for desipramine and Decerebrate Posturing

ArticleYear
Rigid analogues of the α2-adrenergic blocker atipamezole: small changes, big consequences.
    Journal of medicinal chemistry, 2010, Oct-14, Volume: 53, Issue:19

    Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Antihypertensive Age

2010
Pharmacological profile of the 5-HT-induced inhibition of cardioaccelerator sympathetic outflow in pithed rats: correlation with 5-HT1 and putative 5-ht5A/5B receptors.
    British journal of pharmacology, 2003, Volume: 140, Issue:4

    Topics: Animals; Autonomic Fibers, Preganglionic; Blood Pressure; Decerebrate State; Desipramine; Disease Mo

2003
5-hydroxytryptamine inhibits pressor responses to preganglionic sympathetic nerve stimulation in pithed rats.
    Life sciences, 1995, Volume: 57, Issue:8

    Topics: Animals; Autonomic Fibers, Preganglionic; Decerebrate State; Desipramine; Electric Stimulation; Hemo

1995
5-Hydroxytryptamine inhibits the tachycardia induced by selective preganglionic sympathetic stimulation in pithed rats.
    Life sciences, 1999, Volume: 64, Issue:20

    Topics: Animals; Autonomic Fibers, Preganglionic; Decerebrate State; Desipramine; Dose-Response Relationship

1999
Electrophysiological studies with a new anti-depressant drug: comparison of the effects of viloxazine (ICI 58,834) with three tricyclic anti-depressants in the encéphale isolé.
    Neuropharmacology, 1978, Volume: 17, Issue:10

    Topics: Animals; Antidepressive Agents, Tricyclic; Cats; Decerebrate State; Desipramine; Electroencephalogra

1978
Electrocortical changes in the encéphale isolé cat following chronic treatment with antidepressant drugs.
    Neuropharmacology, 1979, Volume: 18, Issue:7

    Topics: Acoustic Stimulation; Amitriptyline; Animals; Antidepressive Agents; Cats; Decerebrate State; Desipr

1979
Comparison of the electrocortical changes induced by (+)-amphetamine and chlorpromazine when perfused directly into the dorsal raphé nucleus of the cat.
    British journal of pharmacology, 1978, Volume: 63, Issue:4

    Topics: Animals; Cats; Chlorpromazine; Decerebrate State; Desipramine; Dextroamphetamine; Drug Interactions;

1978
Nisoxetine prevents the 6-hydroxydopamine induced decrease in post-decapitation convulsions.
    Life sciences, 1977, Jan-15, Volume: 20, Issue:2

    Topics: Animals; Brain Stem; Cerebral Cortex; Decerebrate State; Desipramine; Dose-Response Relationship, Dr

1977
The effects of desipramine (DMI) and alpha-2 adrenoceptor agonists on flexor reflex activity (FRA) in the spinalized and decerebrate rat.
    Journal of neural transmission. General section, 1991, Volume: 84, Issue:1-2

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Cordotomy; Decerebrate State; Desi

1991
Angiotensin II and noradrenergic transmission in the pithed rat.
    Journal of cardiovascular pharmacology, 1989, Volume: 14, Issue:4

    Topics: Angiotensin II; Animals; Captopril; Decerebrate State; Desipramine; Epinephrine; Female; Hemodynamic

1989
Study on the mechanism of 5-HT-induced tachycardia in the pithed rat.
    General pharmacology, 1989, Volume: 20, Issue:6

    Topics: Animals; Chromatography, High Pressure Liquid; Decerebrate State; Desipramine; Heart Rate; Hemodynam

1989
Dopamine1 receptor agonist and alpha-2 adrenoceptor antagonist effects of fenoldopam in rabbits.
    The Journal of pharmacology and experimental therapeutics, 1986, Volume: 239, Issue:3

    Topics: Adrenergic alpha-Antagonists; Animals; Benzazepines; Clonidine; Decerebrate State; Desipramine; Domp

1986
Receptor-mediated effects of serotonin and 5-methoxytryptamine on noradrenaline release in the rat vena cava and in the heart of the pithed rat.
    Naunyn-Schmiedeberg's archives of pharmacology, 1986, Volume: 332, Issue:2

    Topics: 5-Methoxytryptamine; Animals; Blood Pressure; Decerebrate State; Desipramine; Electric Stimulation;

1986
Neuronal and postjunctional components in the blood pressure effects of dopamine and bromocriptine in rabbits.
    The Journal of pharmacology and experimental therapeutics, 1985, Volume: 234, Issue:3

    Topics: Anesthesia; Animals; Benzazepines; Blood Pressure; Bromocriptine; Clonidine; Decerebrate State; Desi

1985
Chronic clorgyline treatment enhances release of norepinephrine following sympathetic stimulation in the rat.
    Naunyn-Schmiedeberg's archives of pharmacology, 1986, Volume: 332, Issue:3

    Topics: Animals; Blood Pressure; Blood Vessels; Clorgyline; Decerebrate State; Desipramine; Electric Stimula

1986
The blockade of bulbospinal inhibition by imipramine, desipramine and pargyline.
    Neuropharmacology, 1974, Volume: 13, Issue:7

    Topics: Animals; Cats; Caudate Nucleus; Decerebrate State; Desipramine; Electric Stimulation; Electrodes, Im

1974
Noradrenergic receptors and the control of fusimotor activity.
    The Journal of physiology, 1972, Volume: 222, Issue:2

    Topics: Animals; Cats; Decerebrate State; Desipramine; Methotrimeprazine; Moxisylyte; Muscle Spindles; Neuro

1972
A comparison of the actions of some drugs on decerebrate rigidity, muscle spindle activity and alpha-adrenoceptors.
    British journal of pharmacology, 1974, Volume: 50, Issue:3

    Topics: Animals; Blood Pressure; Cats; Chlorpromazine; Decerebrate State; Desipramine; Dimethylamines; Dose-

1974