desipramine has been researched along with Coronary Disease in 15 studies
Desipramine: A tricyclic dibenzazepine compound that potentiates neurotransmission. Desipramine selectively blocks reuptake of norepinephrine from the neural synapse, and also appears to impair serotonin transport. This compound also possesses minor anticholinergic activity, through its affinity to muscarinic receptors.
desipramine : A dibenzoazepine consisting of 10,11-dihydro-5H-dibenzo[b,f]azepine substituted on nitrogen with a 3-(methylamino)propyl group.
Coronary Disease: An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (80.00) | 18.7374 |
| 1990's | 3 (20.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| HALL, GF | 1 |
| Dart, AM | 3 |
| Schömig, A | 3 |
| Dietz, R | 1 |
| Mayer, E | 1 |
| Kübler, W | 2 |
| Meredith, IT | 2 |
| Eisenhofer, G | 2 |
| Lambert, GW | 1 |
| Dewar, EM | 1 |
| Jennings, GL | 2 |
| Esler, MD | 2 |
| Shindo, T | 1 |
| Akiyama, T | 1 |
| Yamazaki, T | 1 |
| Ninomiya, I | 1 |
| Cox, HS | 1 |
| Brush, JE | 1 |
| Goldstein, DS | 1 |
| Forfar, JC | 1 |
| Russell, DC | 1 |
| Riemersma, RA | 3 |
| Knopf, H | 1 |
| Theising, R | 1 |
| Hirche, H | 1 |
| Daugherty, A | 1 |
| Frayn, KN | 1 |
| Redfern, WS | 1 |
| Woodward, B | 1 |
| Carlsson, L | 2 |
| Abrahamsson, T | 1 |
| Graefe, KH | 1 |
| Trendelenburg, U | 1 |
| Maxwell, MP | 1 |
| Hearse, DJ | 1 |
| Yellon, DM | 1 |
| Kuz'min, AI | 1 |
| Shul'zhenko, VS | 1 |
| Medvedev, OS | 1 |
| Kapel'ko, VI | 1 |
| Ungar, A | 1 |
| Senges, J | 1 |
15 other studies available for desipramine and Coronary Disease
| Article | Year |
|---|---|
COMBINING ANTIDEPRESSANT DRUGS.
Topics: Antidepressive Agents; Coronary Disease; Desipramine; Heart Failure; Phenelzine; Toxicology | 1965 |
Release of endogenous catecholamines in the ischemic myocardium of the rat. Part B: Effect of sympathetic nerve stimulation.
Topics: Animals; Coronary Disease; Desipramine; Extracellular Space; Myocardium; Norepinephrine; Rats; Sympa | 1984 |
Cardiac sympathetic nervous activity in congestive heart failure. Evidence for increased neuronal norepinephrine release and preserved neuronal uptake.
Topics: Coronary Disease; Desipramine; Dihydroxyphenylalanine; Heart; Heart Failure; Humans; Male; Middle Ag | 1993 |
Regional myocardial interstitial norepinephrine kinetics during coronary occlusion and reperfusion.
Topics: Animals; Blood Pressure; Cats; Coronary Disease; Desipramine; Dialysis; Heart Rate; Kinetics; Myocar | 1996 |
Differences in the neuronal removal of circulating epinephrine and norepinephrine.
Topics: Animals; Coronary Circulation; Coronary Disease; Desipramine; Epinephrine; Female; Humans; Infusions | 1990 |
Control of myocardial catecholamine release during acute ischemia.
Topics: Adenosine; Animals; Coronary Disease; Desipramine; Dogs; Electric Stimulation; Female; Heart; Male; | 1985 |
The effect of desipramine on ischemia-induced changes in extracellular K+, Na+, and H+ concentrations and noradrenaline release in the isolated rat heart during global ischemia.
Topics: Animals; Coronary Disease; Desipramine; Heart; Hydrogen; In Vitro Techniques; Male; Myocardium; Nore | 1988 |
The role of catecholamines in the production of ischaemia-induced ventricular arrhythmias in the rat in vivo and in vitro.
Topics: Adrenal Medulla; Adrenalectomy; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthesi | 1986 |
Characterization of the inhibitory effect of some antidepressant drugs on the outward transport of norepinephrine in the ischemic myocardium.
Topics: Animals; Antidepressive Agents; Biological Transport, Active; Chromatography, High Pressure Liquid; | 1988 |
Origins of endogenous noradrenaline overflow during reperfusion of the ischaemic rat heart.
Topics: Animals; Coronary Disease; Desipramine; Heart; In Vitro Techniques; Male; Models, Cardiovascular; My | 1988 |
Early intraneuronal mobilization and deamination of noradrenaline during global ischemia in the isolated perfused rat heart.
Topics: Animals; Calcium; Coronary Circulation; Coronary Disease; Deamination; Desipramine; Heart; In Vitro | 1987 |
Is there a component of coronary collateral flow which cannot be detected by radiolabelled microspheres?
Topics: Animals; Cats; Cesium Radioisotopes; Collateral Circulation; Coronary Circulation; Coronary Disease; | 1987 |
[Relationship between adenine nucleotide breakdown and catecholamine losses in myocardial ischemia and the recovery of contractile function during reperfusion].
Topics: Adenine Nucleotides; Animals; Catecholamines; Cesium; Chlorides; Coronary Disease; Desipramine; Guin | 1987 |
Metabolic requirements for release of endogenous noradrenaline during myocardial ischaemia and anoxia.
Topics: Animals; Calcium; Coronary Disease; Desipramine; Electric Stimulation; Exocytosis; Ganglia, Sympathe | 1987 |
The conduction and cardiac sympathetic systems: metabolic aspects.
Topics: Animals; Atrioventricular Node; Catecholamines; Cattle; Coronary Disease; Desipramine; Glycolysis; H | 1985 |