desipramine has been researched along with Colonic Neoplasms in 5 studies
Desipramine: A tricyclic dibenzazepine compound that potentiates neurotransmission. Desipramine selectively blocks reuptake of norepinephrine from the neural synapse, and also appears to impair serotonin transport. This compound also possesses minor anticholinergic activity, through its affinity to muscarinic receptors.
desipramine : A dibenzoazepine consisting of 10,11-dihydro-5H-dibenzo[b,f]azepine substituted on nitrogen with a 3-(methylamino)propyl group.
Colonic Neoplasms: Tumors or cancer of the COLON.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In this study, we investigated the effects of fluoxetine, desipramine, and mirtazapine on the liver metastasis of murine C26 colon carcinoma (cc)." | 8.31 | Stimulatory effect of fluoxetine and desipramine, but not mirtazapine on C26 colon carcinoma hepatic metastases formation: association with cytokines. ( Arteta, B; Curzytek, K; Grygier, B; Kubera, M; Maes, M; Malicki, S, 2023) |
| " In this study, we investigated the effects of fluoxetine, desipramine, and mirtazapine on the liver metastasis of murine C26 colon carcinoma (cc)." | 4.31 | Stimulatory effect of fluoxetine and desipramine, but not mirtazapine on C26 colon carcinoma hepatic metastases formation: association with cytokines. ( Arteta, B; Curzytek, K; Grygier, B; Kubera, M; Maes, M; Malicki, S, 2023) |
| "Preclinical studies have suggested that the long-term use of antidepressants may result in the initiation and/or promotion of tumor in the gastrointestinal tract." | 1.33 | Characterization of cytotoxic actions of tricyclic antidepressants on human HT29 colon carcinoma cells. ( Arimochi, H; Morita, K, 2006) |
| "Treatment with desipramine significantly increased the incidence, but not the number, of colon tumors in week 35." | 1.29 | Enhancement by the tricyclic antidepressant, desipramine, of experimental carcinogenesis in rat colon induced by azoxymethane. ( Baba, M; Iishi, H; Taniguchi, H; Tatsuta, M, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kubera, M | 1 |
| Arteta, B | 1 |
| Grygier, B | 1 |
| Curzytek, K | 1 |
| Malicki, S | 1 |
| Maes, M | 1 |
| Kabolizadeh, P | 1 |
| Engelmann, BJ | 1 |
| Pullen, N | 1 |
| Stewart, JK | 1 |
| Ryan, JJ | 1 |
| Farrell, NP | 1 |
| Arimochi, H | 2 |
| Morita, K | 2 |
| Iishi, H | 1 |
| Tatsuta, M | 1 |
| Baba, M | 1 |
| Taniguchi, H | 1 |
5 other studies available for desipramine and Colonic Neoplasms
| Article | Year |
|---|---|
Stimulatory effect of fluoxetine and desipramine, but not mirtazapine on C26 colon carcinoma hepatic metastases formation: association with cytokines.
Topics: Animals; Antidepressive Agents; Carcinoma; Colonic Neoplasms; Cytokines; Desipramine; Fluoxetine; Li | 2023 |
Platinum anticancer agents and antidepressants: desipramine enhances platinum-based cytotoxicity in human colon cancer cells.
Topics: Antidepressive Agents; Antineoplastic Agents; Apoptosis; Cell Proliferation; Colonic Neoplasms; Desi | 2012 |
Characterization of cytotoxic actions of tricyclic antidepressants on human HT29 colon carcinoma cells.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Apoptosis; Cell Cycle; Cell Proliferation; Cell Sur | 2006 |
Desipramine induces apoptotic cell death through nonmitochondrial and mitochondrial pathways in different types of human colon carcinoma cells.
Topics: Adenocarcinoma; Apoptosis; Cell Death; Cell Line, Tumor; Colonic Neoplasms; Desipramine; Dose-Respon | 2008 |
Enhancement by the tricyclic antidepressant, desipramine, of experimental carcinogenesis in rat colon induced by azoxymethane.
Topics: Animals; Azoxymethane; Colonic Neoplasms; Desipramine; Drug Synergism; Male; Norepinephrine; Rats; R | 1993 |