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desipramine and Cognition Disorders

desipramine has been researched along with Cognition Disorders in 6 studies

Desipramine: A tricyclic dibenzazepine compound that potentiates neurotransmission. Desipramine selectively blocks reuptake of norepinephrine from the neural synapse, and also appears to impair serotonin transport. This compound also possesses minor anticholinergic activity, through its affinity to muscarinic receptors.
desipramine : A dibenzoazepine consisting of 10,11-dihydro-5H-dibenzo[b,f]azepine substituted on nitrogen with a 3-(methylamino)propyl group.

Cognition Disorders: Disorders characterized by disturbances in mental processes related to learning, thinking, reasoning, and judgment.

Research Excerpts

ExcerptRelevanceReference
"Desipramine treatment significantly reduced immobility in the tail suspension and forced swim tests, restored sociability in the three-chambered social approach task and reversed impairments in contextual fear conditioning in En2−/− mice."5.40Chronic desipramine treatment rescues depression-related, social and cognitive deficits in Engrailed-2 knockout mice. ( Brielmaier, J; Crawley, JN; DiCicco-Bloom, E; Matteson, PG; Millonig, JH; Senerth, JM; Silverman, JL, 2014)
"Desipramine treatment significantly reduced immobility in the tail suspension and forced swim tests, restored sociability in the three-chambered social approach task and reversed impairments in contextual fear conditioning in En2−/− mice."1.40Chronic desipramine treatment rescues depression-related, social and cognitive deficits in Engrailed-2 knockout mice. ( Brielmaier, J; Crawley, JN; DiCicco-Bloom, E; Matteson, PG; Millonig, JH; Senerth, JM; Silverman, JL, 2014)
"Milnacipran is a serotonin-norepinephrine reuptake inhibitor (SNRI) with moderate preference for blocking norepinephrine reuptake."1.39Effects of milnacipran on cognitive flexibility following chronic stress in rats. ( Banerjee, P; Morilak, DA; Naegeli, KJ; O'Connor, JA, 2013)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19902 (33.33)18.7374
1990's0 (0.00)18.2507
2000's1 (16.67)29.6817
2010's3 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Naegeli, KJ1
O'Connor, JA1
Banerjee, P1
Morilak, DA2
Brielmaier, J1
Senerth, JM1
Silverman, JL1
Matteson, PG1
Millonig, JH1
DiCicco-Bloom, E1
Crawley, JN1
Nikiforuk, A1
Popik, P1
Lapiz, MD1
Bondi, CO1
Frances, A1
Teusink, P1
Fogel, BS1
Sparadeo, FR1

Other Studies

6 other studies available for desipramine and Cognition Disorders

ArticleYear
Effects of milnacipran on cognitive flexibility following chronic stress in rats.
    European journal of pharmacology, 2013, Mar-05, Volume: 703, Issue:1-3

    Topics: Adrenergic Uptake Inhibitors; Animals; Cognition Disorders; Cyclopropanes; Desipramine; Male; Milnac

2013
Chronic desipramine treatment rescues depression-related, social and cognitive deficits in Engrailed-2 knockout mice.
    Genes, brain, and behavior, 2014, Volume: 13, Issue:3

    Topics: Adrenergic Uptake Inhibitors; Animals; Cognition Disorders; Depression; Desipramine; Fear; Homeodoma

2014
Long-lasting cognitive deficit induced by stress is alleviated by acute administration of antidepressants.
    Psychoneuroendocrinology, 2011, Volume: 36, Issue:1

    Topics: Animals; Antidepressive Agents; Attention; Behavior, Animal; Citalopram; Cognition Disorders; Desipr

2011
Chronic treatment with desipramine improves cognitive performance of rats in an attentional set-shifting test.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2007, Volume: 32, Issue:5

    Topics: Adrenergic Uptake Inhibitors; Animals; Attention; Cognition; Cognition Disorders; Depressive Disorde

2007
Elderly patient's confusion confounds diagnosis and treatment of depression.
    Hospital & community psychiatry, 1984, Volume: 35, Issue:11

    Topics: Adjustment Disorders; Aged; Antipsychotic Agents; Cognition Disorders; Confusion; Dementia; Depressi

1984
Focal cognitive deficits accentuated by depression.
    The Journal of nervous and mental disease, 1985, Volume: 173, Issue:2

    Topics: Adult; Brain Diseases; Brain Injuries; Cognition Disorders; Depressive Disorder; Desipramine; Humans

1985