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desipramine and Chronic Motor and Vocal Tic Disorder

desipramine has been researched along with Chronic Motor and Vocal Tic Disorder in 10 studies

Desipramine: A tricyclic dibenzazepine compound that potentiates neurotransmission. Desipramine selectively blocks reuptake of norepinephrine from the neural synapse, and also appears to impair serotonin transport. This compound also possesses minor anticholinergic activity, through its affinity to muscarinic receptors.
desipramine : A dibenzoazepine consisting of 10,11-dihydro-5H-dibenzo[b,f]azepine substituted on nitrogen with a 3-(methylamino)propyl group.

Research Excerpts

ExcerptRelevanceReference
"Desipramine and placebo were similar on "all-cause treatment discontinuation" (RD -0."2.50Tricyclic antidepressants for attention deficit hyperactivity disorder (ADHD) in children and adolescents. ( Castells, X; Ehimare, UP; Otasowie, J; Smith, CH, 2014)
"Only for Tourette's Disorder, Trichotillomania and possibly Sydenham's Chorea have there been convincing biological evidence for continuity with OCD."2.39[The "obsessive-compulsive spectrum": a useful concept?]. ( Rapoport, JL, 1994)
"Because in many patients with Tourette's syndrome (TS) the ADHD symptoms are the major source of disability, alternative nonstimulant treatments are needed."1.29Bupropion exacerbates tics in children with attention-deficit hyperactivity disorder and Tourette's syndrome. ( Biederman, J; Spencer, T; Steingard, R; Wilens, T, 1993)
"As many as 50% of patients with Tourette's syndrome (TS) also meet diagnostic criteria for attention-deficit hyperactivity disorder (ADHD)."1.29Desipramine treatment of children with attention-deficit hyperactivity disorder and tic disorder or Tourette's syndrome. ( Biederman, J; Kerman, K; Spencer, T; Steingard, R; Wilens, T, 1993)
"Therapy for Tourette's syndrome with tricyclic antidepressants has had varied results."1.27A case of Tourette's syndrome with symptoms of attention deficit disorder treated with desipramine. ( Biederman, J; Hoge, SK, 1986)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19904 (40.00)18.7374
1990's4 (40.00)18.2507
2000's1 (10.00)29.6817
2010's1 (10.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Otasowie, J1
Castells, X1
Ehimare, UP1
Smith, CH1
Rojas-Corrales, MO1
Gibert-Rahola, J1
Mico, JA1
Singer, HS1
Brown, J1
Quaskey, S1
Rosenberg, LA1
Mellits, ED1
Denckla, MB1
Rapoport, JL2
Spencer, T2
Biederman, J3
Steingard, R2
Wilens, T2
Kerman, K1
Sweeney, D1
Pickar, D1
Redmond, DE1
Maas, J1
Caine, ED1
Polinsky, RJ1
Ebert, MH1
Mikkelsen, EJ1
Hoge, SK1
Linet, LS1

Reviews

2 reviews available for desipramine and Chronic Motor and Vocal Tic Disorder

ArticleYear
Tricyclic antidepressants for attention deficit hyperactivity disorder (ADHD) in children and adolescents.
    The Cochrane database of systematic reviews, 2014, Sep-19, Issue:9

    Topics: Adolescent; Antidepressive Agents, Tricyclic; Attention Deficit Disorder with Hyperactivity; Central

2014
[The "obsessive-compulsive spectrum": a useful concept?].
    L'Encephale, 1994, Volume: 20 Spec No 4

    Topics: Adolescent; Adult; Clinical Trials as Topic; Clomipramine; Desipramine; Female; Humans; Male; Neuroc

1994

Trials

2 trials available for desipramine and Chronic Motor and Vocal Tic Disorder

ArticleYear
The treatment of attention-deficit hyperactivity disorder in Tourette's syndrome: a double-blind placebo-controlled study with clonidine and desipramine.
    Pediatrics, 1995, Volume: 95, Issue:1

    Topics: Adolescent; Analysis of Variance; Attention Deficit Disorder with Hyperactivity; Child; Clonidine; D

1995
Trial of chlorimipramine and desipramine for Gilles de la Tourette syndrome.
    Annals of neurology, 1979, Volume: 5, Issue:3

    Topics: Adolescent; Adult; Clinical Trials as Topic; Clomipramine; Desipramine; Dibenzazepines; Double-Blind

1979

Other Studies

6 other studies available for desipramine and Chronic Motor and Vocal Tic Disorder

ArticleYear
Role of atypical opiates in OCD. Experimental approach through the study of 5-HT(2A/C) receptor-mediated behavior.
    Psychopharmacology, 2007, Volume: 190, Issue:2

    Topics: 5-Hydroxytryptophan; Analgesics, Opioid; Animals; Clozapine; Desipramine; Disease Models, Animal; Do

2007
Bupropion exacerbates tics in children with attention-deficit hyperactivity disorder and Tourette's syndrome.
    Journal of the American Academy of Child and Adolescent Psychiatry, 1993, Volume: 32, Issue:1

    Topics: Attention Deficit Disorder with Hyperactivity; Bupropion; Child; Clonidine; Desipramine; Female; Hum

1993
Desipramine treatment of children with attention-deficit hyperactivity disorder and tic disorder or Tourette's syndrome.
    Journal of the American Academy of Child and Adolescent Psychiatry, 1993, Volume: 32, Issue:2

    Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Child; Child, Preschool; Comorbidity; Des

1993
Noradrenergic and dopaminergic mechanisms in Gilles de la Tourette syndrome.
    Lancet (London, England), 1978, Apr-22, Volume: 1, Issue:8069

    Topics: Brain; Desipramine; Dopamine; Female; Humans; Middle Aged; Norepinephrine; Tourette Syndrome

1978
A case of Tourette's syndrome with symptoms of attention deficit disorder treated with desipramine.
    The Journal of clinical psychiatry, 1986, Volume: 47, Issue:9

    Topics: Attention Deficit Disorder with Hyperactivity; Child; Desipramine; Humans; Male; Tourette Syndrome

1986
Tourette's syndrome with symptoms of attention deficit disorder treated with desipramine.
    The Journal of clinical psychiatry, 1987, Volume: 48, Issue:11

    Topics: Attention Deficit Disorder with Hyperactivity; Child; Desipramine; Humans; Male; Tourette Syndrome

1987