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desipramine and Childhood Tic Disorders

desipramine has been researched along with Childhood Tic Disorders in 5 studies

Desipramine: A tricyclic dibenzazepine compound that potentiates neurotransmission. Desipramine selectively blocks reuptake of norepinephrine from the neural synapse, and also appears to impair serotonin transport. This compound also possesses minor anticholinergic activity, through its affinity to muscarinic receptors.
desipramine : A dibenzoazepine consisting of 10,11-dihydro-5H-dibenzo[b,f]azepine substituted on nitrogen with a 3-(methylamino)propyl group.

Research Excerpts

ExcerptRelevanceReference
"Treatment with desipramine (mean total daily dose, 3."2.70A double-blind comparison of desipramine and placebo in children and adolescents with chronic tic disorder and comorbid attention-deficit/hyperactivity disorder. ( Bearman, SK; Biederman, J; Coffey, B; Crawford, M; Faraone, SV; Geller, D; Spencer, T; Tarazi, R, 2002)
" In one study, tics limited further dosage increases of methylphenidate."2.58Pharmacological treatment for attention deficit hyperactivity disorder (ADHD) in children with comorbid tic disorders. ( Osland, ST; Pringsheim, T; Steeves, TD, 2018)
"Desipramine and placebo were similar on "all-cause treatment discontinuation" (RD -0."2.50Tricyclic antidepressants for attention deficit hyperactivity disorder (ADHD) in children and adolescents. ( Castells, X; Ehimare, UP; Otasowie, J; Smith, CH, 2014)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19901 (20.00)18.7374
1990's1 (20.00)18.2507
2000's1 (20.00)29.6817
2010's2 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Osland, ST1
Steeves, TD1
Pringsheim, T1
Otasowie, J1
Castells, X1
Ehimare, UP1
Smith, CH1
Rapoport, JL1
Leonard, HL1
Swedo, SE1
Lenane, MC1
Spencer, T1
Biederman, J1
Coffey, B1
Geller, D1
Crawford, M1
Bearman, SK1
Tarazi, R1
Faraone, SV1
Riddle, MA1
Hardin, MT1
Cho, SC1
Woolston, JL1
Leckman, JF1

Reviews

3 reviews available for desipramine and Childhood Tic Disorders

ArticleYear
Pharmacological treatment for attention deficit hyperactivity disorder (ADHD) in children with comorbid tic disorders.
    The Cochrane database of systematic reviews, 2018, 06-26, Volume: 6

    Topics: Adolescent; Atomoxetine Hydrochloride; Attention Deficit Disorder with Hyperactivity; Central Nervou

2018
Tricyclic antidepressants for attention deficit hyperactivity disorder (ADHD) in children and adolescents.
    The Cochrane database of systematic reviews, 2014, Sep-19, Issue:9

    Topics: Adolescent; Antidepressive Agents, Tricyclic; Attention Deficit Disorder with Hyperactivity; Central

2014
Obsessive compulsive disorder in children and adolescents: issues in management.
    The Journal of clinical psychiatry, 1993, Volume: 54 Suppl

    Topics: Adolescent; Age Factors; Behavior Therapy; Child; Child, Preschool; Clomipramine; Comorbidity; Couns

1993

Trials

1 trial available for desipramine and Childhood Tic Disorders

ArticleYear
A double-blind comparison of desipramine and placebo in children and adolescents with chronic tic disorder and comorbid attention-deficit/hyperactivity disorder.
    Archives of general psychiatry, 2002, Volume: 59, Issue:7

    Topics: Adolescent; Age Factors; Antidepressive Agents, Tricyclic; Attention Deficit Disorder with Hyperacti

2002

Other Studies

1 other study available for desipramine and Childhood Tic Disorders

ArticleYear
Desipramine treatment of boys with attention-deficit hyperactivity disorder and tics: preliminary clinical experience.
    Journal of the American Academy of Child and Adolescent Psychiatry, 1988, Volume: 27, Issue:6

    Topics: Attention Deficit Disorder with Hyperactivity; Child; Desipramine; Humans; Male; Tic Disorders

1988