desipramine has been researched along with Chemical Dependence in 82 studies
Desipramine: A tricyclic dibenzazepine compound that potentiates neurotransmission. Desipramine selectively blocks reuptake of norepinephrine from the neural synapse, and also appears to impair serotonin transport. This compound also possesses minor anticholinergic activity, through its affinity to muscarinic receptors.
desipramine : A dibenzoazepine consisting of 10,11-dihydro-5H-dibenzo[b,f]azepine substituted on nitrogen with a 3-(methylamino)propyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Thirteen patients meeting DSM-III-R criteria for panic disorder with or without agoraphobia that started during or shortly after cocaine exposure were treated in the UCLA Anxiety Disorders Program (Los Angeles, CA)." | 7.68 | Low dose desipramine treatment of cocaine-related panic attacks. ( Ackerman, DL; Bystritsky, A; Pasnau, RO, 1991) |
| "Desipramine has been added to methadone maintenance in an attempt to reduce dependence on both substances." | 3.76 | Pharmacological and behavioral treatments of cocaine dependence: controlled studies. ( Arndt, IO; Childress, AR; Maany, I; McLellan, AT; O'Brien, CP; Woody, GE, 1988) |
| "Thirteen patients meeting DSM-III-R criteria for panic disorder with or without agoraphobia that started during or shortly after cocaine exposure were treated in the UCLA Anxiety Disorders Program (Los Angeles, CA)." | 3.68 | Low dose desipramine treatment of cocaine-related panic attacks. ( Ackerman, DL; Bystritsky, A; Pasnau, RO, 1991) |
| "Concerning the comorbid substance use, all the studies have included patients with alcohol use, none of them have dealt with cocaine, cannabis or nicotine use." | 2.82 | Clinical practice guideline on pharmacological and psychological management of adult patients with an anxiety disorder and comorbid substance use. ( Arranz, B; Arrojo, M; Becoña, E; Bernardo, M; Castells, X; Cunill, R; Flórez, G; Fonseca, F; Garriga, M; Goikolea, JM; González-Pinto, A; López, A; Sáiz, PA; San, L; Tirado-Muñoz, J; Torrens, M; Zorrilla, I, 2022) |
| "Desipramine was an effective antidepressant in this sample and was associated with significantly greater reduction in depressive symptoms than was placebo; however, desipramine treatment was not associated with greater reductions in cocaine use for either the depressed or euthymic subgroup." | 2.68 | Differential symptom reduction in depressed cocaine abusers treated with psychotherapy and pharmacotherapy. ( Carroll, KM; Nich, C; Rounsaville, BJ, 1995) |
| "Although patients with a history of substance abuse reported higher levels of anxiety and depression at presentation for treatment than patients without such histories, the two groups reported a similar age of onset of their bulimia nervosa and similar severity of eating pathology with regards to binge and vomit frequencies and measures of concern about body shape and weight." | 2.67 | The impact of prior substance abuse on treatment outcome for bulimia nervosa. ( Pike, KM; Strasser, TJ; Walsh, BT, 1992) |
| " Mean plasma concentration of desipramine in a subsample of our subjects was less than that recommended for treatment of depression, thus the dosage of desipramine may have been subtherapeutic." | 2.67 | Comparison of amantadine and desipramine combined with psychotherapy for treatment of cocaine dependence. ( Brown, BS; Haertzen, CA; Hess, JM; Jaffe, JH; Kolar, AF; Mahaffey, JR; Weddington, WW, 1991) |
| "Informing drug abusers in treatment regarding positive HIV-serostatus was not associated with a lower treatment-retention rate or adverse psychological reactions when counseling regarding HIV issues was integrated with drug abuse treatment." | 2.67 | Psychological reactions and retention by cocaine addicts during treatment according to HIV-serostatus: a matched-control study. ( Brown, BS; Haertzen, CA; Hess, JM; Weddington, WW, 1991) |
| "Desipramine blood levels were taken at weeks 2 (inpatient), 3, and 8." | 2.67 | Continuity of care and desipramine in primary cocaine abusers. ( Banys, P; Clark, HW; Hall, SM; Presti, D; Stewart, P; Triffleman, E; Tunis, S; Tusel, D, 1994) |
| "Thus, antisocial personality disorder was a poor prognostic factor for treatment retention and continued cocaine abuse, and medication did not improve treatment outcome for the ASP patients, but did for the non-ASP patients." | 2.67 | Antisocial personality disorder as a prognostic factor for pharmacotherapy of cocaine dependence. ( Kosten, T; Leal, J; Ziedonis, D, 1994) |
| "Desipramine-treated subjects attained contiguous periods of abstinence substantially more frequently than subjects receiving lithium or placebo." | 2.66 | Desipramine facilitation of initial cocaine abstinence. ( Byck, R; Gawin, FH; Jatlow, PI; Kleber, HD; Kosten, TR; Morgan, C; Rounsaville, BJ, 1989) |
| "Treatment with bromocriptine was significantly more effective than placebo in alleviating withdrawal symptoms." | 2.66 | Bromocriptine-desipramine protocol in treatment of cocaine addiction. ( Billett, W; Giannini, AJ, 1987) |
| "Lithium carbonate was effective only in cyclothymic subjects." | 2.65 | Cocaine abuse treatment. Open pilot trial with desipramine and lithium carbonate. ( Gawin, FH; Kleber, HD, 1984) |
| "Pretreatment with bromocriptine (0." | 1.30 | Effects of proposed treatments for cocaine addiction on hemodynamic responsiveness to cocaine in conscious rats. ( Gan, Q; Knuepfer, MM, 1997) |
| "Desipramine treatment (3." | 1.28 | Desipramine effects on cocaine self-administration by rhesus monkeys. ( Bree, MP; Lukas, SE; Mello, NK; Mendelson, JH, 1990) |
| " Chronic administration of desipramine may have therapeutic efficacy in treating cocaine abuse only in subjects attempting to refrain from cocaine who are aided in their passage through a withdrawal phase by desipramine." | 1.28 | Schedule-induced oral self-administration of cocaine and ethanol solutions: lack of effect of chronic desipramine. ( Falk, JL; Tang, M, 1990) |
| "Desipramine was administered to 8 amphetamine- and 14 cocaine-dependent persons to assist withdrawal." | 1.27 | Cocaine and amphetamine dependence treated with desipramine. ( Rawson, RA; Tennant, FS, 1983) |
| "Desipramine quickly reversed the withdrawal symptoms in both patients, although it did not prevent their future use of cocaine." | 1.27 | Desipramine in the treatment of hypersomnolence following abrupt cessation of cocaine use. ( Baxter, LR, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 31 (37.80) | 18.7374 |
| 1990's | 46 (56.10) | 18.2507 |
| 2000's | 4 (4.88) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (1.22) | 2.80 |
| Authors | Studies |
|---|---|
| Sáiz, PA | 1 |
| Flórez, G | 1 |
| Arrojo, M | 1 |
| Bernardo, M | 1 |
| González-Pinto, A | 1 |
| Goikolea, JM | 1 |
| Zorrilla, I | 1 |
| Cunill, R | 1 |
| Castells, X | 1 |
| Becoña, E | 1 |
| López, A | 1 |
| Torrens, M | 1 |
| Fonseca, F | 1 |
| Tirado-Muñoz, J | 1 |
| Arranz, B | 1 |
| Garriga, M | 1 |
| San, L | 1 |
| Gasior, M | 1 |
| Bergman, J | 1 |
| Kallman, MJ | 1 |
| Paronis, CA | 1 |
| Amitai, Y | 1 |
| Frischer, H | 1 |
| Jasinski, DR | 1 |
| Faries, DE | 1 |
| Moore, RJ | 1 |
| Schuh, LM | 1 |
| Allen, AJ | 1 |
| Tennant, FS | 3 |
| Rawson, RA | 3 |
| Gawin, FH | 9 |
| Kleber, HD | 3 |
| Baxter, LR | 1 |
| McCann, M | 1 |
| Vasiliades, J | 1 |
| Carroll, KM | 4 |
| Nich, C | 4 |
| Rounsaville, BJ | 5 |
| Shoptaw, S | 1 |
| McCann, MJ | 1 |
| Obert, JL | 1 |
| Campbell, JL | 1 |
| Thomas, HM | 1 |
| Gabrielli, W | 1 |
| Liskow, BI | 1 |
| Powell, BJ | 1 |
| Piotrowski, NA | 1 |
| Clark, HW | 2 |
| Hall, SM | 2 |
| Tunis, S | 1 |
| Triffleman, E | 1 |
| Banys, P | 1 |
| Tusel, D | 1 |
| Stewart, P | 1 |
| Presti, D | 1 |
| Gordon, LT | 2 |
| Wirtz, PW | 1 |
| Gawin, F | 2 |
| Kaminer, Y | 2 |
| Leal, J | 1 |
| Ziedonis, D | 2 |
| Kosten, T | 4 |
| Arndt, IO | 4 |
| McLellan, AT | 5 |
| Dorozynsky, L | 3 |
| Woody, GE | 3 |
| O'Brien, CP | 6 |
| Jatlow, P | 4 |
| Bisighini, RM | 1 |
| Kosten, TR | 8 |
| Johnson, DN | 1 |
| Vocci, FJ | 1 |
| Rowe, JB | 1 |
| Sullivan, PF | 1 |
| Mulder, RT | 1 |
| Joyce, PR | 1 |
| Foltin, RW | 3 |
| Fischman, MW | 3 |
| Schottenfeld, RS | 3 |
| Higgins, ST | 1 |
| Budney, AJ | 1 |
| Knuepfer, MM | 1 |
| Gan, Q | 1 |
| Fuchs, RA | 1 |
| Tran-Nguyen, LT | 1 |
| Specio, SE | 1 |
| Groff, RS | 1 |
| Neisewander, JL | 1 |
| Treisman, GJ | 1 |
| Angelino, AF | 1 |
| Hutton, HE | 1 |
| Petit, JM | 1 |
| Biggs, JT | 1 |
| Kolar, AF | 3 |
| Brown, BS | 4 |
| Weddington, WW | 5 |
| Haertzen, CC | 1 |
| Michaelson, BS | 1 |
| Jaffe, JH | 2 |
| Brooke, D | 1 |
| Fudala, PJ | 1 |
| Johnson, RE | 1 |
| See, RE | 1 |
| Adams-Curtis, L | 1 |
| Chapman, MA | 1 |
| Silverman, DG | 1 |
| Fleming, J | 2 |
| Compton, M | 1 |
| Byck, R | 4 |
| Morgan, CM | 1 |
| Falcione, J | 1 |
| Meyer, RE | 1 |
| Delucchi, KL | 1 |
| Richardson, T | 1 |
| Lee, E | 1 |
| Petrakis, I | 1 |
| Strasser, TJ | 1 |
| Pike, KM | 1 |
| Walsh, BT | 1 |
| Bystritsky, A | 1 |
| Ackerman, DL | 1 |
| Pasnau, RO | 1 |
| Ziedonis, DM | 1 |
| Levin, FR | 1 |
| Lehman, AF | 1 |
| Giannini, AJ | 3 |
| Haertzen, CA | 3 |
| Hess, JM | 3 |
| Mahaffey, JR | 2 |
| Pickett, G | 1 |
| Silverman, D | 1 |
| Kosten, TA | 1 |
| Morgan, CH | 1 |
| Goeders, NE | 1 |
| Bienvenu, OJ | 1 |
| De Souza, EB | 1 |
| Mello, NK | 4 |
| Lukas, SE | 1 |
| Bree, MP | 1 |
| Mendelson, JH | 4 |
| Teoh, SK | 2 |
| Weiss, R | 1 |
| McElroy, S | 1 |
| McAfee, B | 2 |
| Morgan, C | 2 |
| Nelson, JC | 1 |
| Tang, M | 1 |
| Falk, JL | 1 |
| Maany, I | 2 |
| Dhopesh, V | 1 |
| Burke, W | 1 |
| Woody, G | 2 |
| Jatlow, PI | 1 |
| Arndt, I | 1 |
| McElroy, SL | 1 |
| Weiss, RD | 2 |
| Alterman, A | 1 |
| Walter, D | 1 |
| Childress, AR | 2 |
| Clark, RJ | 1 |
| Dackis, CA | 2 |
| Gold, MS | 2 |
| Pottash, AL | 1 |
| Bozarth, MA | 1 |
| Wise, RA | 1 |
| Tarver, A | 1 |
| Pumphrey, E | 1 |
| Seecof, R | 1 |
| Schumann, B | 2 |
| Millman, RB | 1 |
| Billett, W | 1 |
| Tennant, F | 1 |
| Berman, ML | 1 |
| Barnes, DM | 1 |
| Malone, DA | 1 |
| Giannini, MC | 1 |
| Price, WA | 1 |
| Loiselle, RH | 1 |
| Wright, D | 1 |
| Carney, MK | 1 |
| Liu, SJ | 1 |
| Wang, RI | 1 |
| Milner, G | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Four Models of Telephone Support for Stimulant Recovery[NCT00744068] | 302 participants (Actual) | Interventional | 2006-04-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
11 reviews available for desipramine and Chemical Dependence
| Article | Year |
|---|---|
Clinical practice guideline on pharmacological and psychological management of adult patients with an anxiety disorder and comorbid substance use.
Topics: Adult; Anxiety Disorders; Desipramine; Humans; Naltrexone; Paroxetine; Substance-Related Disorders | 2022 |
Clinical and research perspectives on cocaine abuse: the pharmacotherapy of cocaine abuse.
Topics: Buprenorphine; Clinical Trials as Topic; Cocaine; Desipramine; Humans; Substance-Related Disorders | 1993 |
Medications development at the National Institute on Drug Abuse: focus on cocaine.
Topics: Bromocriptine; Cocaine; Desipramine; Humans; Substance Withdrawal Syndrome; Substance-Related Disord | 1993 |
Cocaine self-administration research: treatment implications.
Topics: Animals; Choice Behavior; Clinical Trials as Topic; Cocaine; Desipramine; Dose-Response Relationship | 1994 |
From the initial clinic contact to aftercare: a brief review of effective strategies for retaining cocaine abusers in treatment.
Topics: Antidepressive Agents; Appointments and Schedules; Clinical Trials as Topic; Cocaine; Desipramine; F | 1997 |
New pharmacotherapies for cocaine dependence ... revisited.
Topics: Alcoholism; Cocaine; Desipramine; Disease Models, Animal; Double-Blind Method; Heroin Dependence; Hu | 1992 |
Meta-analysis of desipramine as an adjunct in the treatment of cocaine addiction.
Topics: Cocaine; Combined Modality Therapy; Desipramine; Humans; Meta-Analysis as Topic; Substance-Related D | 1991 |
Clinical investigations of drug effects in women.
Topics: Buprenorphine; Cocaine; Desipramine; Female; Heroin Dependence; Humans; Male; Naltrexone; Opioid-Rel | 1986 |
Pharmacological and behavioral treatments of cocaine dependence: controlled studies.
Topics: Animals; Behavior Therapy; Clinical Trials as Topic; Cocaine; Conditioning, Classical; Desipramine; | 1988 |
Evaluation and clinical management of cocaine abusers.
Topics: Acquired Immunodeficiency Syndrome; Antidepressive Agents, Tricyclic; Cocaine; Desipramine; Humans; | 1988 |
Pharmacological approaches to cocaine addiction.
Topics: Brain Chemistry; Bromocriptine; Cocaine; Desipramine; Dopamine; Euphoria; Humans; Receptors, Dopamin | 1985 |
33 trials available for desipramine and Chemical Dependence
| Article | Year |
|---|---|
Abuse liability assessment of atomoxetine in a drug-abusing population.
Topics: Adrenergic Uptake Inhibitors; Adult; Arousal; Atomoxetine Hydrochloride; Central Nervous System Stim | 2008 |
Cocaine abuse treatment. Open pilot trial with desipramine and lithium carbonate.
Topics: Adult; Clinical Trials as Topic; Cocaine; Cyclothymic Disorder; Desipramine; Female; Humans; Lithium | 1984 |
Differential symptom reduction in depressed cocaine abusers treated with psychotherapy and pharmacotherapy.
Topics: Adult; Cocaine; Cognitive Behavioral Therapy; Combined Modality Therapy; Comorbidity; Depressive Dis | 1995 |
The Matrix model of outpatient stimulant abuse treatment: evidence of efficacy.
Topics: Adult; Ambulatory Care; Cocaine; Combined Modality Therapy; Desipramine; Double-Blind Method; Female | 1994 |
Impact of desipramine or carbamazepine on patient retention in outpatient cocaine treatment: preliminary findings.
Topics: Ambulatory Care; Antisocial Personality Disorder; Anxiety Disorders; Carbamazepine; Cocaine; Combine | 1994 |
Treatment research with crack-cocaine-dependent male veterans: the efficacy of different recruitment strategies.
Topics: Adolescent; Adult; Aged; Ambulatory Care; Combined Modality Therapy; Crack Cocaine; Desipramine; Hum | 1994 |
Continuity of care and desipramine in primary cocaine abusers.
Topics: Adult; Ambulatory Care; Cocaine; Continuity of Patient Care; Costs and Cost Analysis; Counseling; De | 1994 |
One-year follow-up of psychotherapy and pharmacotherapy for cocaine dependence. Delayed emergence of psychotherapy effects.
Topics: Adaptation, Psychological; Adult; Ambulatory Care; Behavior Therapy; Cocaine; Cognitive Behavioral T | 1994 |
Antisocial personality disorder as a prognostic factor for pharmacotherapy of cocaine dependence.
Topics: Adult; Amantadine; Antisocial Personality Disorder; Cocaine; Combined Modality Therapy; Comorbidity; | 1994 |
Desipramine treatment for cocaine dependence. Role of antisocial personality disorder.
Topics: Adult; Antisocial Personality Disorder; Cocaine; Comorbidity; Desipramine; Humans; Male; Methadone; | 1994 |
Psychotherapy and pharmacotherapy for ambulatory cocaine abusers.
Topics: Adult; Ambulatory Care; Analysis of Variance; Cocaine; Cognitive Behavioral Therapy; Combined Modali | 1994 |
Blind man's bluff: effectiveness and significance of psychotherapy and pharmacotherapy blinding procedures in a clinical trial.
Topics: Cocaine; Combined Modality Therapy; Desipramine; Double-Blind Method; Humans; Psychotherapy; Substan | 1994 |
The effect of a history of conduct disorder in adult major depression.
Topics: Adolescent; Adult; Alcoholism; Antidepressive Agents, Tricyclic; Child; Child Behavior Disorders; Cl | 1996 |
Treatment of cocaine dependence in methadone maintenance clients: a pilot study comparing the efficacy of desipramine and amantadine.
Topics: Adolescent; Adult; Amantadine; Baltimore; Cocaine; Desipramine; Female; Follow-Up Studies; Humans; M | 1992 |
Weighing up the pros and cons: help-seeking by drug misusers in Baltimore, USA.
Topics: Adult; Bromocriptine; Buprenorphine; Cocaine; Desipramine; Fear; Female; Fluoxetine; Humans; Male; M | 1992 |
Intravenous cocaine challenges during desipramine maintenance.
Topics: Adult; Cardiovascular System; Cocaine; Desipramine; Dose-Response Relationship, Drug; Female; Humans | 1992 |
Desipramine treatment of cocaine dependence in methadone-maintained patients.
Topics: Adult; Cocaine; Comorbidity; Desipramine; Double-Blind Method; Drug Therapy, Combination; Follow-Up | 1992 |
Pharmacotherapy for cocaine-abusing methadone-maintained patients using amantadine or desipramine.
Topics: Adult; Amantadine; Cocaine; Desipramine; Double-Blind Method; Female; Humans; Male; Methadone; Opioi | 1992 |
The impact of prior substance abuse on treatment outcome for bulimia nervosa.
Topics: Adolescent; Adult; Body Weight; Bulimia; Depressive Disorder; Desipramine; Double-Blind Method; Fema | 1992 |
Depression as a prognostic factor for pharmacological treatment of cocaine dependence.
Topics: Adult; Amantadine; Cocaine; Depression; Desipramine; Female; Humans; Male; Prognosis; Psychiatric St | 1991 |
Comparison of amantadine and desipramine combined with psychotherapy for treatment of cocaine dependence.
Topics: Adult; Amantadine; Cocaine; Combined Modality Therapy; Desipramine; Dose-Response Relationship, Drug | 1991 |
Amantadine and desipramine in the treatment of cocaine abusing methadone maintained patients.
Topics: Adult; Amantadine; Cocaine; Desipramine; Double-Blind Method; Female; Humans; Male; Methadone; Opioi | 1990 |
Psychological reactions and retention by cocaine addicts during treatment according to HIV-serostatus: a matched-control study.
Topics: Adaptation, Psychological; Adult; Affect; AIDS Serodiagnosis; Amantadine; Baltimore; Cocaine; Combin | 1991 |
Hyperprolactinemia and risk for relapse of cocaine abuse.
Topics: Adult; Cocaine; Desipramine; Double-Blind Method; Female; Humans; Hyperprolactinemia; Male; Prolacti | 1990 |
Desipramine facilitation of initial cocaine abstinence.
Topics: Adult; Ambulatory Care; Clinical Trials as Topic; Cocaine; Desipramine; Double-Blind Method; Female; | 1989 |
Desipramine treatment of cocaine abuse in methadone maintenance patients.
Topics: Clinical Trials as Topic; Cocaine; Combined Modality Therapy; Desipramine; Double-Blind Method; Huma | 1989 |
Comparison of amantadine and desipramine combined with psychotherapy for treatment of cocaine dependence.
Topics: Amantadine; Clinical Trials as Topic; Cocaine; Combined Modality Therapy; Desipramine; Follow-Up Stu | 1989 |
Desipramine treatment for relapse prevention in cocaine dependence.
Topics: Adult; Cocaine; Desipramine; Double-Blind Method; Female; Humans; Length of Stay; Male; Personality | 1989 |
Evaluation of treatment for cocaine dependence.
Topics: Adult; Behavior Therapy; Cocaine; Combined Modality Therapy; Desipramine; Double-Blind Method; Human | 1989 |
Double-blind comparison of desipramine and placebo for treatment of phencyclidine or amphetamine dependence.
Topics: Amphetamines; Clinical Trials as Topic; Desipramine; Double-Blind Method; Humans; Phencyclidine; Pla | 1986 |
Pharmacological and behavioral treatments of cocaine dependence: controlled studies.
Topics: Animals; Behavior Therapy; Clinical Trials as Topic; Cocaine; Conditioning, Classical; Desipramine; | 1988 |
Bromocriptine-desipramine protocol in treatment of cocaine addiction.
Topics: Adult; Bromocriptine; Clinical Trials as Topic; Cocaine; Desipramine; Drug Therapy, Combination; Hum | 1987 |
Treatment of depression in chronic cocaine and phencyclidine abuse with desipramine.
Topics: Adult; Clinical Trials as Topic; Cocaine; Depression; Desipramine; Humans; Male; Phencyclidine; Plac | 1986 |
39 other studies available for desipramine and Chemical Dependence
| Article | Year |
|---|---|
Evaluation of the reinforcing effects of monoamine reuptake inhibitors under a concurrent schedule of food and i.v. drug delivery in rhesus monkeys.
Topics: Adrenergic Uptake Inhibitors; Animals; Atomoxetine Hydrochloride; Attention Deficit Disorder with Hy | 2005 |
Excess fatality from desipramine in children and adolescents.
Topics: Adolescent; Amitriptyline; Child; Desipramine; Doxepin; Humans; Imipramine; Incidence; Mortality; No | 2006 |
Cocaine and amphetamine dependence treated with desipramine.
Topics: Adult; Amphetamine; Cocaine; Desipramine; Female; Humans; Male; Substance-Related Disorders | 1983 |
Desipramine in the treatment of hypersomnolence following abrupt cessation of cocaine use.
Topics: Adult; Cocaine; Desipramine; Female; Humans; Sleep Wake Disorders; Substance Withdrawal Syndrome; Su | 1983 |
Withdrawal from chronic phencyclidine (PCP) dependence with desipramine.
Topics: Adolescent; Adult; Desipramine; Female; Humans; Male; Phencyclidine; Substance Withdrawal Syndrome; | 1981 |
Identification of misused drugs in the clinical laboratory. I. Tricyclics.
Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Chromatography, Gas; Chromatography, Thin La | 1980 |
Cocaine craving.
Topics: Adolescent; Amitriptyline; Cocaine; Desipramine; Humans; Hypotension, Orthostatic; Male; Risk Factor | 1994 |
Clinical trials of pharmacologic treatments in pregnant women--methodologic considerations.
Topics: Bromocriptine; Buprenorphine; Clinical Trials as Topic; Desipramine; Dopamine Agonists; Female; Huma | 1995 |
Effects of proposed treatments for cocaine addiction on hemodynamic responsiveness to cocaine in conscious rats.
Topics: Animals; Bromocriptine; Buprenorphine; Cocaine; Desipramine; Diazepam; Dizocilpine Maleate; Hemodyna | 1997 |
Predictive validity of the extinction/reinstatement model of drug craving.
Topics: Adrenergic Uptake Inhibitors; Animals; Cocaine; Desipramine; Male; Rats; Rats, Sprague-Dawley; Self | 1998 |
Psychiatric issues in the management of patients with HIV infection.
Topics: Adult; Antidepressive Agents; Attention Deficit Disorder with Hyperactivity; Depressive Disorder, Ma | 2001 |
Tricyclic antidepressant overdoses in adolescent patients.
Topics: Adolescent; Affective Symptoms; Amitriptyline; Antidepressive Agents, Tricyclic; Desipramine; Dose-R | 1977 |
Desipramine facilitation of cocaine abstinence in an adolescent.
Topics: Adolescent; Cocaine; Depressive Disorder; Desipramine; Humans; Male; Personality Inventory; Substanc | 1992 |
Assessment of dopamine release by in vivo microdialysis in the nucleus accumbens of rats following acute and chronic administration of desipramine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Desipramine; Dialysis; Dopamine; Homovanillic Acid; Hydroxy | 1992 |
A laboratory model for evaluating potential treatment medications in humans.
Topics: Cocaine; Desipramine; Humans; Models, Theoretical; Substance-Related Disorders | 1992 |
Research on desipramine in the treatment of cocaine abuse: a critique of Levin and Lehman's meta-analysis.
Topics: Clinical Trials as Topic; Cocaine; Desipramine; Humans; Meta-Analysis as Topic; Research Design; Sub | 1992 |
Adjunctive desipramine in the treatment of cocaine abusing schizophrenics.
Topics: Adult; Cocaine; Desipramine; Female; Humans; Male; Schizophrenia; Schizophrenic Psychology; Substanc | 1992 |
Self-administration of cocaine by humans: a laboratory perspective.
Topics: Choice Behavior; Cocaine; Desipramine; Humans; Laboratories; Self Administration; Substance-Related | 1992 |
Low dose desipramine treatment of cocaine-related panic attacks.
Topics: Adult; Cocaine; Desipramine; Drug Administration Schedule; Drug Evaluation; Female; Humans; Male; Mi | 1991 |
Innovations in use of pharmacological treatments.
Topics: Cocaine; Desipramine; Humans; Peer Review; Psychiatry; Psychotropic Drugs; Substance-Related Disorde | 1991 |
Concurrent effects of acute intravenous cocaine in context of chronic desipramine in humans.
Topics: Adult; Blood Pressure; Cocaine; Desipramine; Drug Interactions; Heart Rate; Humans; Injections, Intr | 1990 |
Chronic cocaine administration alters corticotropin-releasing factor receptors in the rat brain.
Topics: Animals; Autoradiography; Brain; Cerebral Ventricles; Cocaine; Corticotropin-Releasing Hormone; Desi | 1990 |
Use of unproven and unapproved drugs to treat cocaine addiction.
Topics: Clinical Protocols; Cocaine; Desipramine; Drugs, Investigational; Humans; Informed Consent; Substanc | 1990 |
Desipramine effects on cocaine self-administration by rhesus monkeys.
Topics: Animals; Appetitive Behavior; Cocaine; Conditioning, Operant; Desipramine; Dose-Response Relationshi | 1990 |
Evidence for altered desipramine disposition in methadone-maintained patients treated for cocaine abuse.
Topics: Adult; Cocaine; Depressive Disorder; Desipramine; Dose-Response Relationship, Drug; Female; Humans; | 1990 |
Schedule-induced oral self-administration of cocaine and ethanol solutions: lack of effect of chronic desipramine.
Topics: Alcohol Drinking; Alcoholism; Animals; Cocaine; Desipramine; Dose-Response Relationship, Drug; Drug | 1990 |
Increase in desipramine serum levels associated with methadone treatment.
Topics: Adult; Cocaine; Desipramine; Drug Interactions; Drug Therapy, Combination; Humans; Male; Methadone; | 1989 |
The treatment of chemical dependence.
Topics: Cocaine; Desipramine; Humans; Substance-Related Disorders | 1989 |
Central stimulant abuse: neurochemistry and pharmacotherapy.
Topics: Antipsychotic Agents; Brain; Bromocriptine; Cocaine; Desipramine; Dopamine; Euphoria; Humans; Recept | 1986 |
Involvement of the ventral tegmental dopamine system in opioid and psychomotor stimulant reinforcement.
Topics: Animals; Cocaine; Desipramine; Dopamine; Heroin; Heroin Dependence; Hydroxydopamines; Oxidopamine; P | 1986 |
Treating cocaine abusing methadone maintenance patients with desipramine.
Topics: Acquired Immunodeficiency Syndrome; Adult; Cocaine; Desipramine; Female; Heroin Dependence; Humans; | 1988 |
Relapse to cocaine abuse after initiating desipramine treatment.
Topics: Adult; Bulimia; Cocaine; Depressive Disorder; Desipramine; Female; Humans; Male; Recurrence; Substan | 1988 |
Stepwise detoxification from cocaine. A promising regimen.
Topics: Adolescent; Adult; Amantadine; Bromocriptine; Cocaine; Desipramine; Drug Therapy, Combination; Femal | 1988 |
Breaking the cycle of addiction.
Topics: Behavior Therapy; Cocaine; Desipramine; Humans; Mental Disorders; Psychotherapy; Recurrence; Substan | 1988 |
Desipramine augmentation of cocaine abstinence: initial results.
Topics: Cocaine; Desipramine; Double-Blind Method; Drug Evaluation; Humans; Lithium; Psychotherapy; Substanc | 1986 |
A preliminary study of desipramine in the treatment of cocaine abuse in methadone maintenance patients.
Topics: Adult; Antisocial Personality Disorder; Black or African American; Cocaine; Desipramine; Female; Hum | 1987 |
New uses of antidepressants in cocaine abuse.
Topics: Antidepressive Agents; Cocaine; Combined Modality Therapy; Desipramine; Humans; Lithium; Substance-R | 1986 |
Enhanced development of dispositional tolerance to methadone by desipramine given together with methadone.
Topics: Analgesia; Animals; Desipramine; Drug Interactions; Humans; Male; Methadone; Rats; Rats, Inbred Stra | 1985 |
The effect of antidepressants and "tranquilizers" on the response of mice to ethanol.
Topics: Accidents, Traffic; Amitriptyline; Animals; Antidepressive Agents; Chlorpromazine; Coma; Desipramine | 1968 |