desipramine has been researched along with Cardiomyopathies in 2 studies
Desipramine: A tricyclic dibenzazepine compound that potentiates neurotransmission. Desipramine selectively blocks reuptake of norepinephrine from the neural synapse, and also appears to impair serotonin transport. This compound also possesses minor anticholinergic activity, through its affinity to muscarinic receptors.
desipramine : A dibenzoazepine consisting of 10,11-dihydro-5H-dibenzo[b,f]azepine substituted on nitrogen with a 3-(methylamino)propyl group.
Cardiomyopathies: A group of diseases in which the dominant feature is the involvement of the CARDIAC MUSCLE itself. Cardiomyopathies are classified according to their predominant pathophysiological features (DILATED CARDIOMYOPATHY; HYPERTROPHIC CARDIOMYOPATHY; RESTRICTIVE CARDIOMYOPATHY) or their etiological/pathological factors (CARDIOMYOPATHY, ALCOHOLIC; ENDOCARDIAL FIBROELASTOSIS).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Desipramine treatment produced significant NE uptake inhibition as evidence by an exaggerated pressor response and a greater increase of myocardial interstitial NE in response to intravenous NE infusion but no significant effects on cardiac function or hemodynamics in sham-operated or CHF animals." | 5.33 | Cardiac sympathetic neuroprotective effect of desipramine in tachycardia-induced cardiomyopathy. ( Fukuoka, S; Iwai, C; Liang, CS; Mao, W; Stevens, SY, 2006) |
| "Desipramine treatment produced significant NE uptake inhibition as evidence by an exaggerated pressor response and a greater increase of myocardial interstitial NE in response to intravenous NE infusion but no significant effects on cardiac function or hemodynamics in sham-operated or CHF animals." | 1.33 | Cardiac sympathetic neuroprotective effect of desipramine in tachycardia-induced cardiomyopathy. ( Fukuoka, S; Iwai, C; Liang, CS; Mao, W; Stevens, SY, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Liang, CS | 1 |
| Mao, W | 1 |
| Iwai, C | 1 |
| Fukuoka, S | 1 |
| Stevens, SY | 1 |
| Takatsu, H | 1 |
| Uno, Y | 1 |
| Fujiwara, H | 1 |
2 other studies available for desipramine and Cardiomyopathies
| Article | Year |
|---|---|
Cardiac sympathetic neuroprotective effect of desipramine in tachycardia-induced cardiomyopathy.
Topics: Animals; Cardiac Pacing, Artificial; Cardiomyopathies; Desipramine; Heart; Neuroprotective Agents; N | 2006 |
Modulation of left ventricular iodine-125-MIBG accumulation in cardiomyopathic Syrian hamsters using the renin-angiotensin system.
Topics: 3-Iodobenzylguanidine; Animals; Cardiomyopathies; Cilazapril; Coronary Circulation; Cricetinae; Desi | 1995 |