desipramine has been researched along with Cardiac Output, Low in 2 studies
Desipramine: A tricyclic dibenzazepine compound that potentiates neurotransmission. Desipramine selectively blocks reuptake of norepinephrine from the neural synapse, and also appears to impair serotonin transport. This compound also possesses minor anticholinergic activity, through its affinity to muscarinic receptors.
desipramine : A dibenzoazepine consisting of 10,11-dihydro-5H-dibenzo[b,f]azepine substituted on nitrogen with a 3-(methylamino)propyl group.
Cardiac Output, Low: A state of subnormal or depressed cardiac output at rest or during stress. It is a characteristic of CARDIOVASCULAR DISEASES, including congenital, valvular, rheumatic, hypertensive, coronary, and cardiomyopathic. The serious form of low cardiac output is characterized by marked reduction in STROKE VOLUME, and systemic vasoconstriction resulting in cold, pale, and sometimes cyanotic extremities.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Xing, J | 1 |
| Koba, S | 1 |
| Kehoe, V | 1 |
| Gao, Z | 1 |
| Rice, K | 1 |
| King, N | 1 |
| Sinoway, L | 1 |
| Li, J | 1 |
| Eisenhofer, G | 1 |
| Esler, MD | 1 |
| Meredith, IT | 1 |
| Dart, A | 1 |
| Cannon, RO | 1 |
| Quyyumi, AA | 1 |
| Lambert, G | 1 |
| Chin, J | 1 |
| Jennings, GL | 1 |
| Goldstein, DS | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Alpha(2)-Adrenoreceptor (AR) Subtype Polymorphisms and Physiological Responses to Alpha(2)-AR Agonist and Antagonist Drugs[NCT00029627] | 200 participants | Observational | 2002-01-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 other studies available for desipramine and Cardiac Output, Low
| Article | Year |
|---|---|
Interstitial norepinephrine concentrations in skeletal muscle of ischemic heart failure.
Topics: Adrenergic Uptake Inhibitors; Animals; Cardiac Output, Low; Chromatography, High Pressure Liquid; Co | 2007 |
Sympathetic nervous function in human heart as assessed by cardiac spillovers of dihydroxyphenylglycol and norepinephrine.
Topics: Cardiac Output, Low; Catechols; Coronary Vessels; Desipramine; Heart Conduction System; Humans; Meth | 1992 |