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desipramine and Bulimia

desipramine has been researched along with Bulimia in 22 studies

Desipramine: A tricyclic dibenzazepine compound that potentiates neurotransmission. Desipramine selectively blocks reuptake of norepinephrine from the neural synapse, and also appears to impair serotonin transport. This compound also possesses minor anticholinergic activity, through its affinity to muscarinic receptors.
desipramine : A dibenzoazepine consisting of 10,11-dihydro-5H-dibenzo[b,f]azepine substituted on nitrogen with a 3-(methylamino)propyl group.

Bulimia: Eating an excess amount of food in a short period of time, as seen in the disorder of BULIMIA NERVOSA. It is caused by an abnormal craving for food, or insatiable hunger also known as ox hunger.

Research Excerpts

ExcerptRelevanceReference
"A comparison of cognitive-behavior therapy alone, desipramine alone, and cognitive-behavior therapy combined with desipramine was made in the treatment of bulimia nervosa."9.07Comparison of cognitive-behavior therapy and desipramine in the treatment of bulimia nervosa. ( Detzer, MJ; Leitenberg, H; Rosen, JC; Srebnik, D; Vara, LS; Wolf, J, 1994)
"The cardiovascular effects of desipramine were assessed in 74 young women with bulimia nervosa participating in a 6-week double-blind, placebo-controlled study."9.07Increased pulse and blood pressure associated with desipramine treatment of bulimia nervosa. ( Hadigan, CM; Walsh, BT; Wong, LM, 1992)
"Twenty-three women with nonpurging bulimia underwent a 12-week, double-blind, placebo-controlled trial of desipramine hydrochloride."9.06Successful treatment of nonpurging bulimia nervosa with desipramine: a double-blind, placebo-controlled study. ( Agras, WS; McCann, UD, 1990)
"Desipramine was significantly more effective than placebo in reducing the frequency of weekly binding, weekly vomiting, and the fatigue scale of the POMS."6.66Treatment of bulimia with desipramine: a double-blind crossover study. ( Barlow, J; Blouin, A; Blouin, J; Perez, E, 1988)
"At 1-year follow-up, both the combined 24-week treatment and CBT alone were significantly superior in reducing binge eating to desipramine given for 16 weeks."5.07One-year follow-up of psychosocial and pharmacologic treatments for bulimia nervosa. ( Agras, WS; Arnow, B; Bruce, B; Koran, LM; Raeburn, SD; Rossiter, EM; Telch, CF, 1994)
"A comparison of cognitive-behavior therapy alone, desipramine alone, and cognitive-behavior therapy combined with desipramine was made in the treatment of bulimia nervosa."5.07Comparison of cognitive-behavior therapy and desipramine in the treatment of bulimia nervosa. ( Detzer, MJ; Leitenberg, H; Rosen, JC; Srebnik, D; Vara, LS; Wolf, J, 1994)
"The Personality Disorders Examination (PDE) was administered to 71 bulimia nervosa patients at baseline assessment in a study comparing the effectiveness of cognitive-behavioral treatment with desipramine or the combination of both treatments."5.07Cluster B personality disorder characteristics predict outcome in the treatment of bulimia nervosa. ( Agras, WS; Rossiter, EM; Schneider, JA; Telch, CF, 1993)
"The cardiovascular effects of desipramine were assessed in 74 young women with bulimia nervosa participating in a 6-week double-blind, placebo-controlled study."5.07Increased pulse and blood pressure associated with desipramine treatment of bulimia nervosa. ( Hadigan, CM; Walsh, BT; Wong, LM, 1992)
"This study examined the relative effectiveness of desipramine, cognitive-behavioral therapy, and their combination in the treatment of bulimia nervosa, together with the effects of withdrawing medication after two different lengths of treatment."5.07Pharmacologic and cognitive-behavioral treatment for bulimia nervosa: a controlled comparison. ( Agras, WS; Arnow, B; Bruce, B; Koran, LM; Perl, M; Raeburn, SD; Rossiter, EM; Schneider, JA; Telch, CF, 1992)
"The study documents a beneficial effect of desipramine in the treatment of bulimia nervosa when compared to placebo."5.07Long-term outcome of antidepressant treatment for bulimia nervosa. ( Devlin, MJ; Gladis, M; Hadigan, CM; Roose, SP; Walsh, BT, 1991)
"To determine the value of total serum amylase levels and salivary and pancreatic isoenzyme levels as biologic indices of behavioral disturbance in bulimia nervosa, the authors monitored these levels in 40 bulimic patients participating in a placebo-controlled trial of desipramine and in 25 controls."5.06Hyperamylasemia in bulimia nervosa. ( Bodourian, SH; Hadigan, CM; Pesce, MA; Walsh, BT; Wong, LM, 1990)
"Twenty-three women with nonpurging bulimia underwent a 12-week, double-blind, placebo-controlled trial of desipramine hydrochloride."5.06Successful treatment of nonpurging bulimia nervosa with desipramine: a double-blind, placebo-controlled study. ( Agras, WS; McCann, UD, 1990)
"We conducted an exploratory post hoc study that compared the cost effectiveness of five treatments for bulimia nervosa: 15 weeks of cognitive behavioral therapy (CB) followed by three monthly sessions, 16 weeks (Med16) and 24 weeks (Med24) of desipramine (< or = 300 mg/day), and CB combined with desipramine for those durations (Combo16 and Combo24)."3.69Comparing the cost effectiveness of psychiatric treatments: bulimia nervosa. ( Agras, WS; Arnow, B; Bruce, B; Koran, LM; Kraemer, HC; Perl, M; Raeburn, S; Rossiter, EM; Schneider, JA; Telch, CF, 1995)
"Although patients with a history of substance abuse reported higher levels of anxiety and depression at presentation for treatment than patients without such histories, the two groups reported a similar age of onset of their bulimia nervosa and similar severity of eating pathology with regards to binge and vomit frequencies and measures of concern about body shape and weight."2.67The impact of prior substance abuse on treatment outcome for bulimia nervosa. ( Pike, KM; Strasser, TJ; Walsh, BT, 1992)
"Desipramine was significantly more effective than placebo in reducing the frequency of weekly binding, weekly vomiting, and the fatigue scale of the POMS."2.66Treatment of bulimia with desipramine: a double-blind crossover study. ( Barlow, J; Blouin, A; Blouin, J; Perez, E, 1988)

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19906 (27.27)18.7374
1990's16 (72.73)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Agras, WS5
Rossiter, EM4
Arnow, B3
Telch, CF4
Raeburn, SD2
Bruce, B3
Koran, LM3
Leitenberg, H1
Rosen, JC1
Wolf, J1
Vara, LS1
Detzer, MJ1
Srebnik, D1
Walsh, BT8
Giardina, EG1
Sloan, RP1
Greenhill, L1
Goldfein, J1
Ziff, H1
Kominars, K1
Wasserman, C1
Soucar, E1
Schneider, JA3
Raeburn, S1
Perl, M2
Kraemer, HC1
Devlin, MJ4
Wilson, GT2
Loeb, KL2
Pike, KM2
Roose, SP3
Fleiss, J1
Waternaux, C2
Labouvie, E1
Petkova, E1
Liu, X1
Strasser, TJ2
Ames-Frankel, J1
Sadik, C1
Oldham, JM1
Hadigan, CM3
Wong, LM2
Pesce, MA1
Bodourian, SH1
Gladis, M1
McCann, UD1
Blouin, J2
Blouin, A2
Perez, E2
Barlow, J2
Mitchell, JE1
Pyle, RL1
Eckert, ED1
Hatsukami, D1
Pomeroy, C1
Zimmerman, R1
Blouin, AG1
Blouin, JH1
Perez, EL1
Bushnik, T1
Zuro, C1
Mulder, E1
Weiss, RD1
Hughes, PL1
Wells, LA1
Cunningham, CJ1

Reviews

1 review available for desipramine and Bulimia

ArticleYear
Assessment and treatment of binge-eating disorder.
    The Psychiatric clinics of North America, 1996, Volume: 19, Issue:4

    Topics: Adult; Anorexia Nervosa; Antidepressive Agents; Bulimia; Cognitive Behavioral Therapy; Combined Moda

1996

Trials

16 trials available for desipramine and Bulimia

ArticleYear
One-year follow-up of psychosocial and pharmacologic treatments for bulimia nervosa.
    The Journal of clinical psychiatry, 1994, Volume: 55, Issue:5

    Topics: Adolescent; Adult; Aged; Body Weight; Bulimia; Cognitive Behavioral Therapy; Combined Modality Thera

1994
Comparison of cognitive-behavior therapy and desipramine in the treatment of bulimia nervosa.
    Behaviour research and therapy, 1994, Volume: 32, Issue:1

    Topics: Adolescent; Adult; Bulimia; Cognitive Behavioral Therapy; Combined Modality Therapy; Desipramine; Fe

1994
Cluster B personality disorder characteristics predict outcome in the treatment of bulimia nervosa.
    The International journal of eating disorders, 1993, Volume: 13, Issue:4

    Topics: Adolescent; Adult; Body Image; Borderline Personality Disorder; Bulimia; Cognitive Behavioral Therap

1993
Medication and psychotherapy in the treatment of bulimia nervosa.
    The American journal of psychiatry, 1997, Volume: 154, Issue:4

    Topics: Adolescent; Adult; Bulimia; Cognitive Behavioral Therapy; Combined Modality Therapy; Desipramine; Do

1997
Psychological versus pharmacological treatments of bulimia nervosa: predictors and processes of change.
    Journal of consulting and clinical psychology, 1999, Volume: 67, Issue:4

    Topics: Adolescent; Adult; Antidepressive Agents; Bulimia; Cognitive Behavioral Therapy; Desipramine; Female

1999
The impact of prior substance abuse on treatment outcome for bulimia nervosa.
    Addictive behaviors, 1992, Volume: 17, Issue:4

    Topics: Adolescent; Adult; Body Weight; Bulimia; Depressive Disorder; Desipramine; Double-Blind Method; Fema

1992
Personality disorder diagnoses in patients with bulimia nervosa: clinical correlates and changes with treatment.
    The Journal of clinical psychiatry, 1992, Volume: 53, Issue:3

    Topics: Adult; Ambulatory Care; Body Weight; Borderline Personality Disorder; Bulimia; Desipramine; Double-B

1992
Increased pulse and blood pressure associated with desipramine treatment of bulimia nervosa.
    Journal of clinical psychopharmacology, 1992, Volume: 12, Issue:3

    Topics: Adolescent; Adult; Aging; Bulimia; Desipramine; Dose-Response Relationship, Drug; Double-Blind Metho

1992
Hyperamylasemia in bulimia nervosa.
    The Journal of clinical psychiatry, 1990, Volume: 51, Issue:9

    Topics: Adolescent; Adult; Ambulatory Care; Amylases; Body Weight; Bulimia; Desipramine; Female; Humans; Iso

1990
Pharmacologic and cognitive-behavioral treatment for bulimia nervosa: a controlled comparison.
    The American journal of psychiatry, 1992, Volume: 149, Issue:1

    Topics: Adolescent; Adult; Aged; Ambulatory Care; Bulimia; Cognitive Behavioral Therapy; Combined Modality T

1992
Long-term outcome of antidepressant treatment for bulimia nervosa.
    The American journal of psychiatry, 1991, Volume: 148, Issue:9

    Topics: Adult; Bulimia; Desipramine; Double-Blind Method; Female; Follow-Up Studies; Humans; Medical Records

1991
Successful treatment of nonpurging bulimia nervosa with desipramine: a double-blind, placebo-controlled study.
    The American journal of psychiatry, 1990, Volume: 147, Issue:11

    Topics: Appetite; Bulimia; Desipramine; Double-Blind Method; Eating; Female; Humans; Hunger; Outcome and Pro

1990
Bulimia: independence of antibulimic and antidepressant properties of desipramine.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1989, Volume: 34, Issue:1

    Topics: Adult; Bulimia; Clinical Trials as Topic; Depressive Disorder; Desipramine; Dexamethasone; Double-Bl

1989
Response to alternative antidepressants in imipramine nonresponders with bulimia nervosa.
    Journal of clinical psychopharmacology, 1989, Volume: 9, Issue:4

    Topics: Adolescent; Adult; Antidepressive Agents; Bulimia; Clinical Trials as Topic; Desipramine; Feeding Be

1989
Treatment of bulimia with fenfluramine and desipramine.
    Journal of clinical psychopharmacology, 1988, Volume: 8, Issue:4

    Topics: Adolescent; Adult; Body Weight; Bulimia; Clinical Trials as Topic; Depression; Desipramine; Double-B

1988
Treatment of bulimia with desipramine: a double-blind crossover study.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1988, Volume: 33, Issue:2

    Topics: Adult; Bulimia; Clinical Trials as Topic; Desipramine; Double-Blind Method; Follow-Up Studies; Human

1988

Other Studies

5 other studies available for desipramine and Bulimia

ArticleYear
Effects of desipramine on autonomic control of the heart.
    Journal of the American Academy of Child and Adolescent Psychiatry, 1994, Volume: 33, Issue:2

    Topics: Adolescent; Adult; Arousal; Attention Deficit Disorder with Hyperactivity; Autonomic Nervous System;

1994
Pharmacologic and cognitive-behavioral treatment for bulimia nervosa.
    The American journal of psychiatry, 1993, Volume: 150, Issue:10

    Topics: Bulimia; Cognitive Behavioral Therapy; Combined Modality Therapy; Desipramine; Humans; Research Desi

1993
Comparing the cost effectiveness of psychiatric treatments: bulimia nervosa.
    Psychiatry research, 1995, Sep-08, Volume: 58, Issue:1

    Topics: Adolescent; Adult; Antidepressive Agents, Tricyclic; Bulimia; Cognitive Behavioral Therapy; Combined

1995
Relapse to cocaine abuse after initiating desipramine treatment.
    JAMA, 1988, Nov-04, Volume: 260, Issue:17

    Topics: Adult; Bulimia; Cocaine; Depressive Disorder; Desipramine; Female; Humans; Male; Recurrence; Substan

1988
The dexamethasone suppression test in bulimia before and after successful treatment with desipramine.
    The Journal of clinical psychiatry, 1986, Volume: 47, Issue:10

    Topics: Adolescent; Adult; Body Weight; Bulimia; Depressive Disorder; Desipramine; Dexamethasone; Female; Hu

1986