Page last updated: 2024-10-25

desipramine and Breast Neoplasms

desipramine has been researched along with Breast Neoplasms in 3 studies

Desipramine: A tricyclic dibenzazepine compound that potentiates neurotransmission. Desipramine selectively blocks reuptake of norepinephrine from the neural synapse, and also appears to impair serotonin transport. This compound also possesses minor anticholinergic activity, through its affinity to muscarinic receptors.
desipramine : A dibenzoazepine consisting of 10,11-dihydro-5H-dibenzo[b,f]azepine substituted on nitrogen with a 3-(methylamino)propyl group.

Breast Neoplasms: Tumors or cancer of the human BREAST.

Research Excerpts

ExcerptRelevanceReference
"This study compared the efficacy and safety of paroxetine and desipramine with those of placebo in the treatment of depressive disorders in adult women with breast cancer, stages I-IV."9.12A double-blind, multicenter, parallel-group study of paroxetine, desipramine, or placebo in breast cancer patients (stages I, II, III, and IV) with major depression. ( Evans, DL; Goodkin, R; Guo, Y; Lawson, D; Lawson, K; Lewison, B; Manatunga, AK; Musselman, DL; Nemeroff, CB; Penna, S; Porter, M; Somerset, WI, 2006)
"This study compared the efficacy and safety of paroxetine and desipramine with those of placebo in the treatment of depressive disorders in adult women with breast cancer, stages I-IV."5.12A double-blind, multicenter, parallel-group study of paroxetine, desipramine, or placebo in breast cancer patients (stages I, II, III, and IV) with major depression. ( Evans, DL; Goodkin, R; Guo, Y; Lawson, D; Lawson, K; Lewison, B; Manatunga, AK; Musselman, DL; Nemeroff, CB; Penna, S; Porter, M; Somerset, WI, 2006)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's2 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Germain, AR1
Carmody, LC1
Nag, PP1
Morgan, B1
Verplank, L1
Fernandez, C1
Donckele, E1
Feng, Y1
Perez, JR1
Dandapani, S1
Palmer, M1
Lander, ES1
Gupta, PB1
Schreiber, SL1
Munoz, B1
Szpunar, MJ1
Burke, KA1
Dawes, RP1
Brown, EB1
Madden, KS1
Musselman, DL1
Somerset, WI1
Guo, Y1
Manatunga, AK1
Porter, M1
Penna, S1
Lewison, B1
Goodkin, R1
Lawson, K1
Lawson, D1
Evans, DL1
Nemeroff, CB1

Trials

1 trial available for desipramine and Breast Neoplasms

ArticleYear
A double-blind, multicenter, parallel-group study of paroxetine, desipramine, or placebo in breast cancer patients (stages I, II, III, and IV) with major depression.
    The Journal of clinical psychiatry, 2006, Volume: 67, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antidepressive Agents, Tricyclic; Breast; Breast Neoplasms; Comorbid

2006

Other Studies

2 other studies available for desipramine and Breast Neoplasms

ArticleYear
Cinnamides as selective small-molecule inhibitors of a cellular model of breast cancer stem cells.
    Bioorganic & medicinal chemistry letters, 2013, Mar-15, Volume: 23, Issue:6

    Topics: Amides; Breast Neoplasms; Cell Line, Tumor; Drug Screening Assays, Antitumor; Female; Humans; Neopla

2013
The antidepressant desipramine and α2-adrenergic receptor activation promote breast tumor progression in association with altered collagen structure.
    Cancer prevention research (Philadelphia, Pa.), 2013, Volume: 6, Issue:12

    Topics: Adenocarcinoma; Adrenergic alpha-2 Receptor Agonists; Animals; Antidepressive Agents, Tricyclic; Apo

2013