desipramine has been researched along with Brain Ischemia in 2 studies
Desipramine: A tricyclic dibenzazepine compound that potentiates neurotransmission. Desipramine selectively blocks reuptake of norepinephrine from the neural synapse, and also appears to impair serotonin transport. This compound also possesses minor anticholinergic activity, through its affinity to muscarinic receptors.
desipramine : A dibenzoazepine consisting of 10,11-dihydro-5H-dibenzo[b,f]azepine substituted on nitrogen with a 3-(methylamino)propyl group.
Brain Ischemia: Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Global transient cerebral ischemia was performing with the four-vessels occlusion method." | 1.35 | Behavioral effects of four antidepressants on an ischemic rat model of emotional disturbances. ( Bantsiele, GB; Bentué-Ferrer, D; Bourin, M; Laviolle, B; Reymann, JM; Saïkali, S, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Monjas, L | 1 |
| Arce, MP | 1 |
| León, R | 1 |
| Egea, J | 1 |
| Pérez, C | 1 |
| Villarroya, M | 1 |
| López, MG | 1 |
| Gil, C | 1 |
| Conde, S | 1 |
| Rodríguez-Franco, MI | 1 |
| Bantsiele, GB | 1 |
| Bentué-Ferrer, D | 1 |
| Saïkali, S | 1 |
| Laviolle, B | 1 |
| Bourin, M | 1 |
| Reymann, JM | 1 |
2 other studies available for desipramine and Brain Ischemia
| Article | Year |
|---|---|
Enzymatic and solid-phase synthesis of new donepezil-based L- and d-glutamic acid derivatives and their pharmacological evaluation in models related to Alzheimer's disease and cerebral ischemia.
Topics: Alzheimer Disease; Animals; Brain Ischemia; Calcium Channel Blockers; Cholinesterase Inhibitors; Don | 2017 |
Behavioral effects of four antidepressants on an ischemic rat model of emotional disturbances.
Topics: Analysis of Variance; Animals; Antidepressive Agents; Anxiety Disorders; Behavior, Animal; Brain Isc | 2009 |