desipramine has been researched along with Body Weight in 78 studies
Desipramine: A tricyclic dibenzazepine compound that potentiates neurotransmission. Desipramine selectively blocks reuptake of norepinephrine from the neural synapse, and also appears to impair serotonin transport. This compound also possesses minor anticholinergic activity, through its affinity to muscarinic receptors.
desipramine : A dibenzoazepine consisting of 10,11-dihydro-5H-dibenzo[b,f]azepine substituted on nitrogen with a 3-(methylamino)propyl group.
Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The current study assessed whether paliperidone, a dopamine D2 receptor and adrenergic alpha-2 receptor antagonist like clozapine, would attenuate alcohol drinking in the alcohol-preferring P rat and the Syrian golden hamster, and whether desipramine, a norepinephrine reuptake inhibitor, would potentiate the ability of paliperidone to attenuate alcohol drinking in the P rat and the Syrian golden hamster." | 7.81 | Desipramine enhances the ability of paliperidone to decrease alcohol drinking. ( Chau, DT; Dawson, R; Green, AI; Gulick, D; Khokhar, JY, 2015) |
| "Twenty-six patients with major depressive disorder were treated with desipramine for 4 weeks to determine the effect of the drug on body weight." | 7.67 | The effect of desipramine on body weight in depression. ( Esche, I; Joffe, RT; Levitt, AJ; Sherret, D, 1987) |
| " The results obtained show that the variables which are most associated with the reduction of enuresis are, in decreasing order: the dosage of imipramine administered, the duration of treatment, compliance and the level/dose ratio for the sum of the drug and metabolite levels." | 5.28 | The influence of clinical and pharmacological factors on enuresis treatment with imipramine. ( Domínguez-Gil, A; Fernández de Gatta, MM; Galindo, P; García, MJ; Gutierrez, J; Rey, F; Tamayo, M, 1990) |
| "Amitriptyline treatment either caused no change in food intake and body weight or slightly reduced levels in comparison to vehicle-treated controls." | 5.27 | Effects of chronic amitriptyline and desipramine on food intake and body weight in rats. ( Coscina, DV; Nobrega, JN, 1987) |
| "At 1-year follow-up, both the combined 24-week treatment and CBT alone were significantly superior in reducing binge eating to desipramine given for 16 weeks." | 5.07 | One-year follow-up of psychosocial and pharmacologic treatments for bulimia nervosa. ( Agras, WS; Arnow, B; Bruce, B; Koran, LM; Raeburn, SD; Rossiter, EM; Telch, CF, 1994) |
| " Three tricyclic antidepressants examined (imipramine, clomipramine and desipramine) did not seem to have the side effect of pathological weight gain in the frequency distribution pattern." | 5.07 | Changes in the frequency distribution pattern of body weight in patients with major depression. ( Kato, T; Murashita, J; Shioiri, T; Takahashi, S; Yamada, N, 1993) |
| "To determine the value of total serum amylase levels and salivary and pancreatic isoenzyme levels as biologic indices of behavioral disturbance in bulimia nervosa, the authors monitored these levels in 40 bulimic patients participating in a placebo-controlled trial of desipramine and in 25 controls." | 5.06 | Hyperamylasemia in bulimia nervosa. ( Bodourian, SH; Hadigan, CM; Pesce, MA; Walsh, BT; Wong, LM, 1990) |
| " The current study assessed whether paliperidone, a dopamine D2 receptor and adrenergic alpha-2 receptor antagonist like clozapine, would attenuate alcohol drinking in the alcohol-preferring P rat and the Syrian golden hamster, and whether desipramine, a norepinephrine reuptake inhibitor, would potentiate the ability of paliperidone to attenuate alcohol drinking in the P rat and the Syrian golden hamster." | 3.81 | Desipramine enhances the ability of paliperidone to decrease alcohol drinking. ( Chau, DT; Dawson, R; Green, AI; Gulick, D; Khokhar, JY, 2015) |
| " In this study we analyzed the effects of the long-term administration of the tricyclic antidepressant desipramine and the reversibility of this treatment following a 15-day washout period on different parameters in parotid gland function in aging rats." | 3.71 | An analysis of parotid salivary gland function with desipramine and age in female NIA Fischer 344 rats. ( Cowman, RA; Humphreys-Beher, MG; Koller, MM; Scarpace, PJ, 2001) |
| "Twenty-six patients with major depressive disorder were treated with desipramine for 4 weeks to determine the effect of the drug on body weight." | 3.67 | The effect of desipramine on body weight in depression. ( Esche, I; Joffe, RT; Levitt, AJ; Sherret, D, 1987) |
| " The significant findings were: (1) triazolam and DMI given alone and in combination were synergistic with pentobarbital (PB) hypnosis; (2) repeated treatment with DMI alone repressed body weight gain; triazolam potentiated this anorectic effect; (3) triazolam induced muscle relaxation acutely, but was not affected by concomitant DMI treatment; and (4) triazolam and DMI given in combination produced hypothermia although the drugs given separately did not." | 3.66 | Interaction of triazolam with desipramine. Effects of single and repeated treatment on certain pharmacologic responses and brain catecholamine levels. ( Horikawa, A; Kusaka, M; Maruyama, Y; Meshi, T, 1980) |
| "Although patients with a history of substance abuse reported higher levels of anxiety and depression at presentation for treatment than patients without such histories, the two groups reported a similar age of onset of their bulimia nervosa and similar severity of eating pathology with regards to binge and vomit frequencies and measures of concern about body shape and weight." | 2.67 | The impact of prior substance abuse on treatment outcome for bulimia nervosa. ( Pike, KM; Strasser, TJ; Walsh, BT, 1992) |
| " These include biological factors, such as strain, age, body weight, gender and individual differences between animals; influence of preconditioning before the FST: handling, social isolation or enriched environment, food manipulations, various kinds of stress, endocrine manipulations and surgery; schedule and routes of treatment, dosage and type of the drugs as well as experimental design and laboratory environmental effects." | 2.49 | Factors influencing behavior in the forced swim test. ( Bogdanova, OV; D'Anci, KE; Kanekar, S; Renshaw, PF, 2013) |
| "Thus, overnutrition due to fats may be central to childhood psychological perturbations such as anxiety and ADHD." | 1.39 | Methylphenidate prevents high-fat diet (HFD)-induced learning/memory impairment in juvenile mice. ( Chiu, GS; Freund, GG; Gainey, SJ; Kaczmarczyk, MM; Kelley, KW; Kwakwa, KA; Lawson, MA; Machaj, AS; Martin, SA; Meling, DD; Miller, MJ; Newman, AF; Wang, Y; Woods, JA; York, JM, 2013) |
| " Dose-response assessments demonstrated that rats housed in EE showed reduced sensitivity to the behavioural effects of DZP and DMI but increased sensitivity to the locomotor-enhancing effects of AMP compared to SC and IC; while IC animals exhibited the clearest dose-response effects to increasing doses of DMI." | 1.38 | The effects of isolated and enriched housing conditions on baseline and drug-induced behavioural responses in the male rat. ( Kelly, JP; Simpson, J, 2012) |
| "The respective adverse effects of imipramine and desipramine on serum thyroid hormone levels and their accumulation in thyroid were investigated in male Wistar rats." | 1.30 | Thyroid accumulation and adverse effects of imipramine and desipramine in rats after long-term administration. ( Buxeraud, J; Lachâtre, G; Lagorce, JF; Marquet, P; Raby, C; Rousseau, A; Sauvage, MF, 1998) |
| "Pretreatment with desipramine and mianserin in combination induced the most intense 5-HT syndrome and the greatest fall in colonic temperature after injection of the 5-HT1A agonist 8-hydroxy-2-(di-n-propylamino)-tetralin (8-OH-DPAT)." | 1.29 | Chronic, combined treatment with desipramine and mianserin: enhanced 5-HT1A receptor function and altered 5-HT1A/5-HT2 receptor interaction in rats. ( Lund, A; Mjellem, N, 1993) |
| "In studies of the effect on nociception of chronic administration of antidepressants, the stress of the injections may influence the results." | 1.28 | Chronic administration of desipramine and zimelidine changes the behavioural response in the formalin test in rats. ( Hole, K; Lund, A; Mjellem-Joly, N, 1991) |
| " Complete dose-response functions for cocaine (0." | 1.28 | The effects of cocaine on food intake of baboons before, during, and after a period of repeated desipramine. ( Fischman, MW; Foltin, RW; Nautiyal, C, 1990) |
| " The results obtained show that the variables which are most associated with the reduction of enuresis are, in decreasing order: the dosage of imipramine administered, the duration of treatment, compliance and the level/dose ratio for the sum of the drug and metabolite levels." | 1.28 | The influence of clinical and pharmacological factors on enuresis treatment with imipramine. ( Domínguez-Gil, A; Fernández de Gatta, MM; Galindo, P; García, MJ; Gutierrez, J; Rey, F; Tamayo, M, 1990) |
| "Desipramine-treated rats did not learn the task in contrast to control animals." | 1.28 | Effects of desipramine on rat behavior are prevented by concomitant treatment with ethanol. ( Rommelspacher, H; Widjaja, S; Wolffgramm, J, 1989) |
| "Treatment with prazosin, an alpha 1-noradrenergic receptor antagonist, reduced Na+-K+-ATPase in either control or cafeteria diet-fed rats but did not alter the effect of cafeteria diet feeding." | 1.27 | Caloric intake and Na+-K+-ATPase: differential regulation by alpha 1- and beta-noradrenergic receptors. ( Swann, AC, 1984) |
| "Amitriptyline treatment either caused no change in food intake and body weight or slightly reduced levels in comparison to vehicle-treated controls." | 1.27 | Effects of chronic amitriptyline and desipramine on food intake and body weight in rats. ( Coscina, DV; Nobrega, JN, 1987) |
| " Chronic administration of DMI caused a reduction in pressing under a CRF schedule both in naive and well-trained rats." | 1.27 | Performance and extinction of lever press behavior following chronic administration of desipramine to rats. ( Frazer, A; Lucki, I, 1985) |
| " Following completion of the dose-response determination for the effect of desipramine or water intake, rats were divided into three groups for repeated administration." | 1.26 | The effect of repeated desipramine administration on water intake in rats. ( O'Donnell, JM; Rider, DP; Seiden, LS; Somani, S, 1982) |
| "In imipramine-treated patients this finding was associated with a decreased rate of drug elimination from plasma." | 1.26 | Relationship between age and tricyclic antidepressant plasma levels. ( Cooper, TB; Friedman, MJ; Green, R; Ives, JO; Nies, A; Ravaris, CL; Robinson, DS, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 38 (48.72) | 18.7374 |
| 1990's | 19 (24.36) | 18.2507 |
| 2000's | 14 (17.95) | 29.6817 |
| 2010's | 7 (8.97) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kaczmarczyk, MM | 1 |
| Machaj, AS | 1 |
| Chiu, GS | 1 |
| Lawson, MA | 1 |
| Gainey, SJ | 1 |
| York, JM | 1 |
| Meling, DD | 1 |
| Martin, SA | 1 |
| Kwakwa, KA | 1 |
| Newman, AF | 1 |
| Woods, JA | 1 |
| Kelley, KW | 1 |
| Wang, Y | 1 |
| Miller, MJ | 1 |
| Freund, GG | 1 |
| Bogdanova, OV | 1 |
| Kanekar, S | 1 |
| D'Anci, KE | 1 |
| Renshaw, PF | 1 |
| Listowska, M | 1 |
| Glac, W | 1 |
| Grembecka, B | 1 |
| Grzybowska, M | 1 |
| Wrona, D | 1 |
| Chau, DT | 1 |
| Khokhar, JY | 1 |
| Gulick, D | 1 |
| Dawson, R | 1 |
| Green, AI | 1 |
| Nava, N | 1 |
| Treccani, G | 1 |
| Alabsi, A | 1 |
| Kaastrup Mueller, H | 1 |
| Elfving, B | 1 |
| Popoli, M | 1 |
| Wegener, G | 1 |
| Nyengaard, JR | 1 |
| Mathieu, G | 1 |
| Denis, S | 1 |
| Lavialle, M | 1 |
| Vancassel, S | 1 |
| Getachew, B | 1 |
| Hauser, SR | 1 |
| Taylor, RE | 1 |
| Tizabi, Y | 1 |
| Estrada-Camarena, E | 1 |
| López-Rubalcava, C | 1 |
| Hernández-Aragón, A | 1 |
| Mejía-Mauries, S | 1 |
| Picazo, O | 1 |
| Simpson, J | 1 |
| Kelly, JP | 2 |
| Carson, RP | 1 |
| Diedrich, A | 1 |
| Robertson, D | 1 |
| Kamei, J | 1 |
| Miyata, S | 1 |
| Morita, K | 1 |
| Saitoh, A | 1 |
| Takeda, H | 1 |
| Papakostas, GI | 1 |
| Petersen, T | 1 |
| Iosifescu, DV | 1 |
| Burns, AM | 1 |
| Nierenberg, AA | 1 |
| Alpert, JE | 1 |
| Rosenbaum, JF | 2 |
| Fava, M | 1 |
| Yalcin, I | 1 |
| Aksu, F | 1 |
| Belzung, C | 1 |
| Santibañez, M | 1 |
| Gysling, K | 1 |
| Forray, MI | 1 |
| Gonzalez, MM | 1 |
| Aston-Jones, G | 1 |
| Swann, AC | 1 |
| Kusaka, M | 1 |
| Horikawa, A | 1 |
| Meshi, T | 1 |
| Maruyama, Y | 1 |
| Wood, JM | 1 |
| Lénárd, L | 3 |
| Hahn, Z | 2 |
| O'Donnell, JM | 1 |
| Rider, DP | 1 |
| Somani, S | 1 |
| Seiden, LS | 2 |
| Karádi, Z | 1 |
| Weller, EB | 1 |
| Weller, RA | 1 |
| Preskorn, SH | 1 |
| Glotzbach, R | 1 |
| Willner, P | 3 |
| Theodorou, A | 1 |
| Montgomery, A | 1 |
| Rudorfer, MV | 1 |
| Young, RC | 1 |
| Montgomery, T | 1 |
| Snyder, DL | 1 |
| Gayheart, P | 1 |
| Johnson, MD | 1 |
| Gurdal, H | 1 |
| Roberts, J | 1 |
| Wesson, VA | 1 |
| Levitt, AJ | 2 |
| Joffe, RT | 2 |
| Agras, WS | 1 |
| Rossiter, EM | 1 |
| Arnow, B | 1 |
| Telch, CF | 1 |
| Raeburn, SD | 1 |
| Bruce, B | 1 |
| Koran, LM | 1 |
| Szarek, BL | 1 |
| Brandt, DM | 1 |
| Shioiri, T | 1 |
| Kato, T | 1 |
| Murashita, J | 1 |
| Yamada, N | 1 |
| Takahashi, S | 1 |
| Lund, A | 2 |
| Mjellem, N | 1 |
| Gálosi, R | 1 |
| Hajnal, A | 1 |
| Fendler, K | 1 |
| Rousseau, A | 1 |
| Marquet, P | 1 |
| Lagorce, JF | 1 |
| Sauvage, MF | 1 |
| Buxeraud, J | 1 |
| Lachâtre, G | 1 |
| Raby, C | 1 |
| Ukai, M | 1 |
| Maeda, H | 1 |
| Nanya, Y | 1 |
| Kameyama, T | 1 |
| Matsuno, K | 1 |
| Shen, Y | 1 |
| Connor, TJ | 1 |
| Nolan, Y | 1 |
| Leonard, BE | 1 |
| Glick, SD | 1 |
| Haskew, RE | 1 |
| Maisonneuve, IM | 1 |
| Carlson, JN | 1 |
| Jerussi, TP | 1 |
| Koller, MM | 3 |
| Maeda, N | 1 |
| Scarpace, PJ | 3 |
| Humphreys-Beher, MG | 3 |
| Cowman, RA | 2 |
| D'Aquila, PS | 1 |
| Peana, AT | 1 |
| Carboni, V | 1 |
| Serra, G | 1 |
| Cabassi, A | 1 |
| Vinci, S | 1 |
| Quartieri, F | 1 |
| Moschini, L | 1 |
| Borghetti, A | 1 |
| Ashley, DV | 1 |
| Coscina, DV | 2 |
| Anderson, GH | 1 |
| Breese, GR | 2 |
| Vogel, RA | 1 |
| Mueller, RA | 1 |
| Erinoff, L | 1 |
| MacPhail, RC | 1 |
| Heller, A | 1 |
| Saller, CF | 1 |
| Stricker, EM | 2 |
| Nies, A | 1 |
| Robinson, DS | 1 |
| Friedman, MJ | 1 |
| Green, R | 1 |
| Cooper, TB | 2 |
| Ravaris, CL | 1 |
| Ives, JO | 1 |
| Liu, SJ | 1 |
| Wang, RI | 1 |
| Melchior, CL | 1 |
| Myers, RD | 1 |
| Cooper, BR | 1 |
| Holt, KG | 1 |
| Strasser, TJ | 2 |
| Pike, KM | 1 |
| Walsh, BT | 3 |
| Pappas, BA | 1 |
| Murtha, SJ | 1 |
| Park, GA | 1 |
| Condon, KT | 1 |
| Szirtes, RM | 1 |
| Laventure, SI | 1 |
| Ally, A | 1 |
| Ames-Frankel, J | 1 |
| Devlin, MJ | 1 |
| Sadik, C | 1 |
| Oldham, JM | 1 |
| Roose, SP | 1 |
| Spencer, T | 1 |
| Biederman, J | 1 |
| Wright, V | 1 |
| Danon, M | 1 |
| Wong, LM | 1 |
| Pesce, MA | 1 |
| Hadigan, CM | 1 |
| Bodourian, SH | 1 |
| Mjellem-Joly, N | 1 |
| Hole, K | 1 |
| Foltin, RW | 1 |
| Fischman, MW | 1 |
| Nautiyal, C | 1 |
| Fernández de Gatta, MM | 1 |
| Galindo, P | 1 |
| Rey, F | 1 |
| Gutierrez, J | 1 |
| Tamayo, M | 1 |
| García, MJ | 1 |
| Domínguez-Gil, A | 1 |
| Rommelspacher, H | 1 |
| Wolffgramm, J | 1 |
| Widjaja, S | 1 |
| Cross, JA | 2 |
| Horton, RW | 2 |
| Moor, M | 1 |
| Honegger, UE | 1 |
| Wiesmann, UN | 1 |
| Blouin, AG | 1 |
| Blouin, JH | 1 |
| Perez, EL | 1 |
| Bushnik, T | 1 |
| Zuro, C | 1 |
| Mulder, E | 1 |
| Muscat, R | 1 |
| Towell, A | 1 |
| Stern, SL | 1 |
| Johnson, MH | 1 |
| Jones, BA | 1 |
| Nelson, LD | 1 |
| Smeltzer, DJ | 1 |
| Nobrega, JN | 1 |
| Leshem, M | 1 |
| Kreider, M | 1 |
| Garland, EJ | 1 |
| Remick, RA | 1 |
| Hughes, PL | 1 |
| Wells, LA | 1 |
| Cunningham, CJ | 1 |
| Esche, I | 1 |
| Sherret, D | 1 |
| Lucki, I | 1 |
| Frazer, A | 1 |
| Roffler-Tarlov, S | 1 |
| Schildkraut, JJ | 1 |
| Draskoczy, PR | 1 |
| Ahlskog, JE | 2 |
| Hoebel, BG | 1 |
| Watt, DC | 1 |
| Crammer, JL | 1 |
| Elkes, A | 1 |
| Zigmond, MJ | 1 |
| Aeppli, L | 1 |
2 reviews available for desipramine and Body Weight
| Article | Year |
|---|---|
Factors influencing behavior in the forced swim test.
Topics: Aging; Animals; Antidepressive Agents; Behavior, Animal; Body Weight; Conditioning, Psychological; D | 2013 |
Treatment of outpatients with desipramine.
Topics: Ambulatory Care; Anxiety Disorders; Body Weight; Depressive Disorder; Desipramine; Drug Administrati | 1984 |
8 trials available for desipramine and Body Weight
| Article | Year |
|---|---|
Obesity among outpatients with major depressive disorder.
Topics: Adult; Ambulatory Care; Antidepressive Agents, Second-Generation; Body Mass Index; Body Weight; Depr | 2005 |
One-year follow-up of psychosocial and pharmacologic treatments for bulimia nervosa.
Topics: Adolescent; Adult; Aged; Body Weight; Bulimia; Cognitive Behavioral Therapy; Combined Modality Thera | 1994 |
Changes in the frequency distribution pattern of body weight in patients with major depression.
Topics: Adult; Antidepressive Agents, Tricyclic; Body Weight; Clomipramine; Depressive Disorder; Desipramine | 1993 |
The impact of prior substance abuse on treatment outcome for bulimia nervosa.
Topics: Adolescent; Adult; Body Weight; Bulimia; Depressive Disorder; Desipramine; Double-Blind Method; Fema | 1992 |
Personality disorder diagnoses in patients with bulimia nervosa: clinical correlates and changes with treatment.
Topics: Adult; Ambulatory Care; Body Weight; Borderline Personality Disorder; Bulimia; Desipramine; Double-B | 1992 |
Hyperamylasemia in bulimia nervosa.
Topics: Adolescent; Adult; Ambulatory Care; Amylases; Body Weight; Bulimia; Desipramine; Female; Humans; Iso | 1990 |
Treatment of bulimia with fenfluramine and desipramine.
Topics: Adolescent; Adult; Body Weight; Bulimia; Clinical Trials as Topic; Depression; Desipramine; Double-B | 1988 |
Metabolism, anticholinergic effects, and therapeutic outcome of desmethylimipramine in depressive illness.
Topics: Adult; Aged; Body Weight; Clinical Trials as Topic; Depression; Desipramine; Dose-Response Relations | 1972 |
68 other studies available for desipramine and Body Weight
| Article | Year |
|---|---|
Methylphenidate prevents high-fat diet (HFD)-induced learning/memory impairment in juvenile mice.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antidepressive Agents; Anxiety; Blood Glucose; Body Weight; | 2013 |
Changes in blood CD4+T and CD8+T lymphocytes in stressed rats pretreated chronically with desipramine are more pronounced after chronic open field stress challenge.
Topics: Animals; Antidepressive Agents, Tricyclic; Apoptosis; Body Weight; CD4-Positive T-Lymphocytes; CD8-P | 2015 |
Desipramine enhances the ability of paliperidone to decrease alcohol drinking.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic Uptake Inhibitors; Alcohol Deterrents; Alcohol D | 2015 |
Temporal Dynamics of Acute Stress-Induced Dendritic Remodeling in Medial Prefrontal Cortex and the Protective Effect of Desipramine.
Topics: Actin Depolymerizing Factors; Animals; Antidepressive Agents, Tricyclic; Atrophy; Body Weight; Corti | 2017 |
Synergistic effects of stress and omega-3 fatty acid deprivation on emotional response and brain lipid composition in adult rats.
Topics: Animals; Animals, Newborn; Arachidonic Acid; Behavior, Animal; Body Weight; Brain Chemistry; Depress | 2008 |
Desipramine blocks alcohol-induced anxiety- and depressive-like behaviors in two rat strains.
Topics: Administration, Inhalation; Animals; Antidepressive Agents, Tricyclic; Anxiety; Body Weight; Central | 2008 |
Long-term ovariectomy modulates the antidepressant-like action of estrogens, but not of antidepressants.
Topics: Age Factors; Animals; Antidepressive Agents; Body Weight; Desipramine; Estradiol; Estrus; Female; Fl | 2011 |
The effects of isolated and enriched housing conditions on baseline and drug-induced behavioural responses in the male rat.
Topics: Amphetamine; Analysis of Variance; Animals; Anti-Anxiety Agents; Behavior, Animal; Body Weight; Cent | 2012 |
Autonomic control after blockade of the norepinephrine transporter: a model of orthostatic intolerance.
Topics: Adrenergic Uptake Inhibitors; Animals; Baroreflex; Blood Pressure; Body Weight; Desipramine; Female; | 2002 |
Effects of selective serotonin reuptake inhibitors on immobility time in the tail suspension test in streptozotocin-induced diabetic mice.
Topics: Adrenergic Uptake Inhibitors; Animals; Anti-Anxiety Agents; Blood Glucose; Body Weight; Desipramine; | 2003 |
Effects of desipramine and tramadol in a chronic mild stress model in mice are altered by yohimbine but not by pindolol.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Analgesics, Opioid; Animals; Antidepressi | 2005 |
Desipramine prevents the sustained increase in corticotropin-releasing hormone-like immunoreactivity induced by repeated immobilization stress in the rat central extended amygdala.
Topics: Adrenal Glands; Amygdala; Animals; Antidepressive Agents, Tricyclic; Anxiety; Body Weight; Corticotr | 2006 |
Light deprivation damages monoamine neurons and produces a depressive behavioral phenotype in rats.
Topics: Animals; Apoptosis; Behavior, Animal; Biogenic Amines; Body Weight; Darkness; Depression; Desipramin | 2008 |
Caloric intake and Na+-K+-ATPase: differential regulation by alpha 1- and beta-noradrenergic receptors.
Topics: 4-Nitrophenylphosphatase; Adipose Tissue, Brown; Animals; Body Weight; Desipramine; Diet; Eating; En | 1984 |
Interaction of triazolam with desipramine. Effects of single and repeated treatment on certain pharmacologic responses and brain catecholamine levels.
Topics: Animals; Anti-Anxiety Agents; Body Weight; Brain Chemistry; Catecholamines; Desipramine; Drug Intera | 1980 |
Effect of depletion of brain 5-hydroxytryptamine by 5,7-dihydroxytryptamine on ethanol tolerance and dependence in the rat.
Topics: 5,7-Dihydroxytryptamine; Alcoholism; Animals; Body Weight; Brain Chemistry; Desipramine; Dihydroxytr | 1980 |
Amygdalar noradrenergic and dopaminergic mechanisms in the regulation of hunger and thirst-motivated behavior.
Topics: Amygdala; Animals; Behavior, Animal; Body Weight; Desipramine; Dopamine; Drinking; Eating; Hunger; H | 1982 |
The effect of repeated desipramine administration on water intake in rats.
Topics: Amitriptyline; Animals; Body Weight; Desipramine; Dose-Response Relationship, Drug; Drinking Behavio | 1982 |
Body weight changes after neurochemical manipulations of lateral amygdala: noradrenergic and dopaminergic mechanisms.
Topics: Amygdala; Animals; Body Weight; Brain Mapping; Desipramine; Dopamine; Feeding Behavior; Hydroxydopam | 1982 |
Steady-state plasma imipramine levels in prepubertal depressed children.
Topics: Age Factors; Body Height; Body Weight; Child; Depressive Disorder; Desipramine; Humans; Imipramine; | 1982 |
Subchronic treatment with the tricyclic antidepressant DMI increases isolation-induced fighting in rats.
Topics: Aggression; Agonistic Behavior; Animals; Body Weight; Desipramine; Dose-Response Relationship, Drug; | 1981 |
Plasma desipramine levels after single dosage and at steady state in outpatients.
Topics: Adult; Body Weight; Depression; Desipramine; Humans; Time Factors | 1980 |
Attenuation of amphetamine anorexia in rats following subchronic treatment with a tricyclic antidepressant.
Topics: Amphetamine; Animals; Antidepressive Agents, Tricyclic; Body Weight; Desipramine; Eating; Male; Rats | 1980 |
Prenatal cocaine exposure alters norepinephrine release from cardiac adrenergic nerve terminals.
Topics: Adrenergic Fibers; Animals; Body Weight; Cocaine; Desipramine; Female; Heart; Ionomycin; Male; Myoca | 1995 |
Change in folate status with antidepressant treatment.
Topics: Adult; Body Weight; Cross-Sectional Studies; Depressive Disorder; Desipramine; Erythrocytes; Female; | 1994 |
A comparison of weight changes with fluoxetine, desipramine, and amitriptyline: a retrospective study of psychiatric inpatients.
Topics: Amitriptyline; Body Weight; Desipramine; Dose-Response Relationship, Drug; Drug Therapy, Combination | 1993 |
Chronic, combined treatment with desipramine and mianserin: enhanced 5-HT1A receptor function and altered 5-HT1A/5-HT2 receptor interaction in rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Behavior, Animal; Body Temperature; B | 1993 |
Effect of catecholaminergic lesions of medial prefrontal cortex on regulation of body weight and glucose preference.
Topics: Animals; Appetite; Body Weight; Catecholamines; Desipramine; Drug Combinations; Glucose; Male; Oxido | 1997 |
Thyroid accumulation and adverse effects of imipramine and desipramine in rats after long-term administration.
Topics: Animals; Antidepressive Agents, Tricyclic; Body Weight; Desipramine; Imipramine; Male; Rats; Rats, W | 1998 |
Beneficial effects of acute and repeated administrations of sigma receptor agonists on behavioral despair in mice exposed to tail suspension.
Topics: Animals; Anisoles; Antidepressive Agents; Body Weight; Desipramine; Drug Interactions; Fluoxetine; H | 1998 |
Differential effect of chronic antidepressant treatments on lipopolysaccharide-induced depressive-like behavioural symptoms in the rat.
Topics: Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Beha | 1999 |
Enantioselective behavioral effects of sibutramine metabolites.
Topics: Animals; Appetite Depressants; Behavior, Animal; Biogenic Monoamines; Body Weight; Cyclobutanes; Des | 2000 |
Desipramine changes salivary gland function, oral microbiota, and oral health in rats.
Topics: Adrenergic Uptake Inhibitors; alpha-Amylases; Animals; Body Weight; Desipramine; DNA; Female; Gingiv | 2000 |
An analysis of submandibular salivary gland function with desipramine and age in female NIA Fischer 344 rats.
Topics: Aging; Animals; Antidepressive Agents, Tricyclic; Body Weight; Desipramine; DNA; Female; Organ Size; | 2000 |
An analysis of parotid salivary gland function with desipramine and age in female NIA Fischer 344 rats.
Topics: Aging; Animals; Antidepressive Agents, Tricyclic; Body Weight; Desipramine; DNA; Female; Organ Size; | 2001 |
Different effect of desipramine on locomotor activity in quinpirole-treated rats after repeated restraint and chronic mild stress.
Topics: Animals; Antidepressive Agents, Tricyclic; Body Weight; Desipramine; Dopamine Agonists; Male; Motor | 2000 |
Norepinephrine reuptake is impaired in skeletal muscle of hypertensive rats in vivo.
Topics: Adipose Tissue; Adrenergic Uptake Inhibitors; Age Factors; Animals; Baroreflex; Blood Pressure; Body | 2001 |
Selective decrease in protein intake following brain serotonin depletion.
Topics: 5,7-Dihydroxytryptamine; Animals; Body Weight; Brain; Desipramine; Dietary Proteins; Energy Metaboli | 1979 |
Biochemical and behavioral alterations in developing rats treated with 5,7-dihydroxytryptamine.
Topics: 5-Hydroxytryptophan; 5,7-Dihydroxytryptamine; Aging; Animals; Avoidance Learning; Behavior, Animal; | 1978 |
Age-dependent effects of 6-hydroxydopamine on locomotor activity in the rat.
Topics: Age Factors; Animals; Body Weight; Catecholamines; Desipramine; Female; Hydroxydopamines; Injections | 1979 |
Gastrointestinal motility and body weight gain in rats after brain serotonin depletion by 5, 7-dihydroxytryptamine.
Topics: 5,7-Dihydroxytryptamine; Animals; Biogenic Amines; Body Weight; Brain; Desipramine; Dihydroxytryptam | 1978 |
Relationship between age and tricyclic antidepressant plasma levels.
Topics: Administration, Oral; Adult; Age Factors; Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Bod | 1977 |
Enhanced development of tolerance to pentobarbital by desipramine inhibition of pentobarbital metabolism.
Topics: Animals; Body Weight; Desipramine; Drug Interactions; Drug Tolerance; Male; Microsomes, Liver; Mixed | 1976 |
Genetic differences in ethanol drinking of the rat following injection of 6-OHDA, 5,6-DHT or 5,7-DHT into the cerebral ventricles.
Topics: 5,6-Dihydroxytryptamine; Alcohol Drinking; Animals; Body Weight; Brain Chemistry; Desipramine; Dopam | 1976 |
Behavioral and biochemical interactions of 5,7-dihydroxytryptamine with various drugs when administered intracisternally to adult and developing rats.
Topics: 5,6-Dihydroxytryptamine; Aggression; Animals; Animals, Newborn; Avoidance Learning; Biogenic Amines; | 1975 |
Growth deficits and desipramine.
Topics: Appetite; Attention Deficit Disorder with Hyperactivity; Body Weight; Child; Depressive Disorder; De | 1992 |
Neonatal brain dopamine depletion and the cortical and behavioral consequences of enriched postweaning environment.
Topics: Animals; Animals, Newborn; Anxiety; Behavior, Animal; Body Weight; Brain Chemistry; Catecholamines; | 1992 |
Growth deficits in children treated with desipramine: a controlled study.
Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Body Height; Body Weight; Child; Desipram | 1992 |
Chronic administration of desipramine and zimelidine changes the behavioural response in the formalin test in rats.
Topics: Animals; Behavior, Animal; Body Temperature; Body Weight; Desipramine; Drinking; Male; Pain Measurem | 1991 |
The effects of cocaine on food intake of baboons before, during, and after a period of repeated desipramine.
Topics: Animals; Body Weight; Cocaine; Desipramine; Dose-Response Relationship, Drug; Drug Interactions; Eat | 1990 |
The influence of clinical and pharmacological factors on enuresis treatment with imipramine.
Topics: Adolescent; Age Factors; Body Weight; Child; Child, Preschool; Desipramine; Enuresis; Female; Humans | 1990 |
Effects of desipramine on rat behavior are prevented by concomitant treatment with ethanol.
Topics: 5-Hydroxytryptophan; Adenylyl Cyclases; Albuterol; Animals; Apomorphine; Avoidance Learning; Behavio | 1989 |
Are increases in GABAB receptors consistent findings following chronic antidepressant administration?
Topics: Animals; Antidepressive Agents; Body Weight; Desipramine; Injections, Intraperitoneal; Kinetics; Mal | 1987 |
Effects of chronic oral administration of the antidepressants, desmethylimipramine and zimelidine on rat cortical GABAB binding sites: a comparison with 5-HT2 binding site changes.
Topics: Animals; Antidepressive Agents; Body Weight; Cerebral Cortex; Desipramine; Hippocampus; Ketanserin; | 1988 |
Organ-specific, qualitative changes in the phospholipid composition of rats after chronic administration of the antidepressant drug desipramine.
Topics: Animals; Body Weight; Desipramine; Male; Organ Specificity; Phospholipids; Rats; Rats, Inbred Strain | 1988 |
Changes in dopamine autoreceptor sensitivity in an animal model of depression.
Topics: Animals; Apomorphine; Body Weight; Depression; Desipramine; Disease Models, Animal; Eating; Male; Ra | 1988 |
Lack of weight gain under desipramine.
Topics: Adult; Body Weight; Depressive Disorder; Desipramine; Female; Humans; Male; Middle Aged | 1987 |
Effects of chronic amitriptyline and desipramine on food intake and body weight in rats.
Topics: Amitriptyline; Animals; Body Weight; Deoxyglucose; Desipramine; Feeding Behavior; Female; Infusion P | 1987 |
Brain serotonin depletion and nipple attachment in rat pups.
Topics: 5,7-Dihydroxytryptamine; Animals; Animals, Suckling; Body Weight; Brain; Desipramine; Feeding Behavi | 1987 |
Desipramine and weight gain.
Topics: Body Weight; Depressive Disorder; Desipramine; Humans | 1987 |
The dexamethasone suppression test in bulimia before and after successful treatment with desipramine.
Topics: Adolescent; Adult; Body Weight; Bulimia; Depressive Disorder; Desipramine; Dexamethasone; Female; Hu | 1986 |
The effect of desipramine on body weight in depression.
Topics: Adult; Body Weight; Depressive Disorder; Desipramine; Dose-Response Relationship, Drug; Female; Huma | 1987 |
Performance and extinction of lever press behavior following chronic administration of desipramine to rats.
Topics: Animals; Body Weight; Brain; Conditioning, Operant; Desipramine; Dihydroalprenolol; Extinction, Psyc | 1985 |
Effects of acute and chronic administration of desmethylimipramine on the content of norepinephrine and other monoamines in the rat brain.
Topics: Administration, Oral; Animals; Biogenic Amines; Body Weight; Brain; Brain Chemistry; Desipramine; Do | 1973 |
Food intake and amphetamine anorexia after selective forebrain norepinephrine loss.
Topics: Amphetamine; Animals; Appetite; Body Weight; Brain Chemistry; Cerebral Cortex; Desipramine; Drinking | 1974 |
Overeating and obesity from damage to a noradrenergic system in the brain.
Topics: Animals; Appetite Regulation; Body Weight; Catecholamines; Denervation; Desipramine; Dextroamphetami | 1973 |
Effects on homeostasis of intraventricular injections of 6-hydroxydopamine in rats.
Topics: Animals; Appetite; Avoidance Learning; Body Temperature Regulation; Body Weight; Brain Chemistry; Br | 1974 |
[Teratologic studies with imipramine in rats and rabbits. Planning and interpretation of teratologic studies under consideration of the biochemistry and toxicology of test substance].
Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Animals; Body Weight; Desipramine; Drug Toleranc | 1969 |