desipramine has been researched along with Benign Neoplasms, Brain in 5 studies
Desipramine: A tricyclic dibenzazepine compound that potentiates neurotransmission. Desipramine selectively blocks reuptake of norepinephrine from the neural synapse, and also appears to impair serotonin transport. This compound also possesses minor anticholinergic activity, through its affinity to muscarinic receptors.
desipramine : A dibenzoazepine consisting of 10,11-dihydro-5H-dibenzo[b,f]azepine substituted on nitrogen with a 3-(methylamino)propyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Treatment of rat C6 glioma cells with the tricyclic antidepressant desipramine induces opioid binding." | 7.69 | A monoclonal anti-idiotypic antibody to opioid receptors labels desipramine-induced opioid binding sites on rat C6 glioma cells and attenuates thymidine incorporation into DNA. ( Barg, J; Belcheva, MM; Coscia, CJ; Johnson, FE; Levy, R; McHale, RJ; McLachlan, JA; Vogel, Z, 1994) |
| "Treatment of rat C6 glioma cells with the tricyclic antidepressant desipramine induces opioid binding." | 3.69 | A monoclonal anti-idiotypic antibody to opioid receptors labels desipramine-induced opioid binding sites on rat C6 glioma cells and attenuates thymidine incorporation into DNA. ( Barg, J; Belcheva, MM; Coscia, CJ; Johnson, FE; Levy, R; McHale, RJ; McLachlan, JA; Vogel, Z, 1994) |
| " We report here an early and important decrease in sphingomyelinase activity in C6 glioma cells cultured in the presence of imipramine or desipramine at final concentrations of 0." | 3.66 | Effect of tricyclic antidepressants on sphingomyelinase and other sphingolipid hydrolases in C6 cultured glioma cells. ( Albouz, S; Baumann, N; Boutry, JM; Hauw, JJ; Le Saux, F; Vanier, MT, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zou, F | 1 |
| Pusch, S | 1 |
| Hua, J | 1 |
| Ma, T | 1 |
| Yang, L | 1 |
| Zhu, Q | 1 |
| Xu, Y | 1 |
| Gu, Y | 1 |
| von Deimling, A | 1 |
| Zha, X | 1 |
| Staudacher, I | 1 |
| Jehle, J | 1 |
| Staudacher, K | 1 |
| Pledl, HW | 1 |
| Lemke, D | 1 |
| Schweizer, PA | 1 |
| Becker, R | 1 |
| Katus, HA | 1 |
| Thomas, D | 1 |
| Golan, M | 1 |
| Schreiber, G | 1 |
| Avissar, S | 1 |
| Albouz, S | 1 |
| Vanier, MT | 1 |
| Hauw, JJ | 1 |
| Le Saux, F | 1 |
| Boutry, JM | 1 |
| Baumann, N | 1 |
| Barg, J | 1 |
| Belcheva, MM | 1 |
| Levy, R | 1 |
| McHale, RJ | 1 |
| McLachlan, JA | 1 |
| Johnson, FE | 1 |
| Coscia, CJ | 1 |
| Vogel, Z | 1 |
5 other studies available for desipramine and Benign Neoplasms, Brain
| Article | Year |
|---|---|
Identification of novel allosteric inhibitors of mutant isocitrate dehydrogenase 1 by cross docking-based virtual screening.
Topics: Allosteric Site; Blood-Brain Barrier; Brain Neoplasms; Dose-Response Relationship, Drug; Drug Evalua | 2018 |
HERG K+ channel-dependent apoptosis and cell cycle arrest in human glioblastoma cells.
Topics: Apoptosis; Brain Neoplasms; Caspase 9; Cell Cycle Checkpoints; Cell Line, Tumor; Cytoprotection; Des | 2014 |
Antidepressants elevate GDNF expression and release from C₆ glioma cells in a β-arrestin1-dependent, CREB interactive pathway.
Topics: Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents; Antimanic Agents; Antipsychotic Agents | 2011 |
Effect of tricyclic antidepressants on sphingomyelinase and other sphingolipid hydrolases in C6 cultured glioma cells.
Topics: Animals; Brain; Brain Neoplasms; Culture Techniques; Desipramine; Dose-Response Relationship, Drug; | 1983 |
A monoclonal anti-idiotypic antibody to opioid receptors labels desipramine-induced opioid binding sites on rat C6 glioma cells and attenuates thymidine incorporation into DNA.
Topics: Animals; Antibodies, Monoclonal; Brain Neoplasms; Cell Division; Cell Membrane; Colorimetry; Densito | 1994 |