desipramine has been researched along with Autonomic Failure, Progressive in 2 studies
Desipramine: A tricyclic dibenzazepine compound that potentiates neurotransmission. Desipramine selectively blocks reuptake of norepinephrine from the neural synapse, and also appears to impair serotonin transport. This compound also possesses minor anticholinergic activity, through its affinity to muscarinic receptors.
desipramine : A dibenzoazepine consisting of 10,11-dihydro-5H-dibenzo[b,f]azepine substituted on nitrogen with a 3-(methylamino)propyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Desipramine treatment was associated with decreased 6-(18)F-fluorodopamine-derived radioactivity in the heart, renal cortex, and thyroid gland but not in the liver, spleen, renal pelvis, or salivary glands." | 2.71 | Cardiac and extracardiac sympathetic denervation in Parkinson's disease with orthostatic hypotension and in pure autonomic failure. ( Goldstein, DS; Tipre, DN, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Carson, RP | 1 |
| Diedrich, A | 1 |
| Robertson, D | 1 |
| Tipre, DN | 1 |
| Goldstein, DS | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effects of Supplementing Tyrosine on Blood Pressure in Parkinson's Disease[NCT01676103] | Phase 1/Phase 2 | 40 participants (Actual) | Interventional | 2012-09-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for desipramine and Autonomic Failure, Progressive
| Article | Year |
|---|---|
Cardiac and extracardiac sympathetic denervation in Parkinson's disease with orthostatic hypotension and in pure autonomic failure.
Topics: Adult; Aged; Autonomic Nervous System; Autonomic Nervous System Diseases; Desipramine; Dopamine; Flu | 2005 |
1 other study available for desipramine and Autonomic Failure, Progressive
| Article | Year |
|---|---|
Autonomic control after blockade of the norepinephrine transporter: a model of orthostatic intolerance.
Topics: Adrenergic Uptake Inhibitors; Animals; Baroreflex; Blood Pressure; Body Weight; Desipramine; Female; | 2002 |