desipramine has been researched along with Autism in 2 studies
Desipramine: A tricyclic dibenzazepine compound that potentiates neurotransmission. Desipramine selectively blocks reuptake of norepinephrine from the neural synapse, and also appears to impair serotonin transport. This compound also possesses minor anticholinergic activity, through its affinity to muscarinic receptors.
desipramine : A dibenzoazepine consisting of 10,11-dihydro-5H-dibenzo[b,f]azepine substituted on nitrogen with a 3-(methylamino)propyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To determine whether clomipramine hydrochloride, a serotonin reuptake blocker with unique anti-obsessional properties, is differentially effective for obsessive-compulsive and stereotyped motor behaviors in autistic disorder compared with placebo and with the noradrenergic tricyclic antidepressant agent, desipramine hydrochloride." | 9.07 | A double-blind comparison of clomipramine, desipramine, and placebo in the treatment of autistic disorder. ( Gordon, CT; Hamburger, SD; Nelson, JE; Rapoport, JL; State, RC, 1993) |
| "Clomipramine, a serotonin reuptake blocker that has unique antiobsessional properties, was hypothesized to have a different effect from that of desipramine, a tricyclic antidepressant with selective adrenergic effects, for the stereotyped, repetitive behaviors in autism." | 9.07 | Differential response of seven subjects with autistic disorder to clomipramine and desipramine. ( Gordon, CT; Hamburger, SD; Mannheim, GB; Rapoport, JL; State, RC, 1992) |
| "To determine whether clomipramine hydrochloride, a serotonin reuptake blocker with unique anti-obsessional properties, is differentially effective for obsessive-compulsive and stereotyped motor behaviors in autistic disorder compared with placebo and with the noradrenergic tricyclic antidepressant agent, desipramine hydrochloride." | 5.07 | A double-blind comparison of clomipramine, desipramine, and placebo in the treatment of autistic disorder. ( Gordon, CT; Hamburger, SD; Nelson, JE; Rapoport, JL; State, RC, 1993) |
| "Clomipramine, a serotonin reuptake blocker that has unique antiobsessional properties, was hypothesized to have a different effect from that of desipramine, a tricyclic antidepressant with selective adrenergic effects, for the stereotyped, repetitive behaviors in autism." | 5.07 | Differential response of seven subjects with autistic disorder to clomipramine and desipramine. ( Gordon, CT; Hamburger, SD; Mannheim, GB; Rapoport, JL; State, RC, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gordon, CT | 2 |
| State, RC | 2 |
| Nelson, JE | 1 |
| Hamburger, SD | 2 |
| Rapoport, JL | 2 |
| Mannheim, GB | 1 |
2 trials available for desipramine and Autism
| Article | Year |
|---|---|
A double-blind comparison of clomipramine, desipramine, and placebo in the treatment of autistic disorder.
Topics: Adolescent; Adult; Ambulatory Care; Autistic Disorder; Child; Clomipramine; Desipramine; Double-Blin | 1993 |
Differential response of seven subjects with autistic disorder to clomipramine and desipramine.
Topics: Adolescent; Anger; Autistic Disorder; Child; Clomipramine; Compulsive Behavior; Desipramine; Double- | 1992 |