Page last updated: 2024-10-25

desipramine and Antisocial Behavior

desipramine has been researched along with Antisocial Behavior in 7 studies

Desipramine: A tricyclic dibenzazepine compound that potentiates neurotransmission. Desipramine selectively blocks reuptake of norepinephrine from the neural synapse, and also appears to impair serotonin transport. This compound also possesses minor anticholinergic activity, through its affinity to muscarinic receptors.
desipramine : A dibenzoazepine consisting of 10,11-dihydro-5H-dibenzo[b,f]azepine substituted on nitrogen with a 3-(methylamino)propyl group.

Antisocial Behavior: Behavior that sharply deviates from social norms and violates rights of others

Research Excerpts

ExcerptRelevanceReference
"Thus, antisocial personality disorder was a poor prognostic factor for treatment retention and continued cocaine abuse, and medication did not improve treatment outcome for the ASP patients, but did for the non-ASP patients."2.67Antisocial personality disorder as a prognostic factor for pharmacotherapy of cocaine dependence. ( Kosten, T; Leal, J; Ziedonis, D, 1994)
"Nortriptyline was reported in one study as superior for men with alcohol dependency on mean number of drinking days and on alcohol dependence, but not for severity of alcohol misuse or on the patient's or clinician's rating of drinking."2.46Pharmacological interventions for antisocial personality disorder. ( Duggan, C; Ferriter, M; Huband, N; Khalifa, N; Lieb, K; Stoffers, J; Völlm, BA, 2010)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19902 (28.57)18.7374
1990's3 (42.86)18.2507
2000's0 (0.00)29.6817
2010's1 (14.29)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
Khalifa, NR1
Gibbon, S1
Völlm, BA2
Cheung, NH1
McCarthy, L1
Khalifa, N1
Duggan, C1
Stoffers, J1
Huband, N1
Ferriter, M1
Lieb, K1
Campbell, JL1
Thomas, HM1
Gabrielli, W1
Liskow, BI1
Powell, BJ1
Leal, J1
Ziedonis, D1
Kosten, T1
Arndt, IO1
McLellan, AT1
Dorozynsky, L1
Woody, GE1
O'Brien, CP1
Kosten, TR1
Schumann, B1
Wright, D1
Carney, MK1
Gawin, FH1
von Schumann, HJ1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Effect of Fluoxetine on Measures of Domestic Violence[NCT00011765]Phase 2104 participants (Actual)Interventional2001-02-22Completed
Medication Development for Cocaine Dependence[NCT00249691]Phase 3180 participants (Anticipated)Interventional2005-10-31Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for desipramine and Antisocial Behavior

ArticleYear
Pharmacological interventions for antisocial personality disorder.
    The Cochrane database of systematic reviews, 2020, 09-03, Volume: 9

    Topics: Adult; Aggression; Alcohol-Related Disorders; Amantadine; Antisocial Personality Disorder; Anxiety;

2020
Pharmacological interventions for antisocial personality disorder.
    The Cochrane database of systematic reviews, 2020, 09-03, Volume: 9

    Topics: Adult; Aggression; Alcohol-Related Disorders; Amantadine; Antisocial Personality Disorder; Anxiety;

2020
Pharmacological interventions for antisocial personality disorder.
    The Cochrane database of systematic reviews, 2020, 09-03, Volume: 9

    Topics: Adult; Aggression; Alcohol-Related Disorders; Amantadine; Antisocial Personality Disorder; Anxiety;

2020
Pharmacological interventions for antisocial personality disorder.
    The Cochrane database of systematic reviews, 2020, 09-03, Volume: 9

    Topics: Adult; Aggression; Alcohol-Related Disorders; Amantadine; Antisocial Personality Disorder; Anxiety;

2020
Pharmacological interventions for antisocial personality disorder.
    The Cochrane database of systematic reviews, 2010, Aug-04, Issue:8

    Topics: Adult; Aggression; Alcohol-Related Disorders; Amantadine; Antisocial Personality Disorder; Anxiety;

2010

Trials

3 trials available for desipramine and Antisocial Behavior

ArticleYear
Impact of desipramine or carbamazepine on patient retention in outpatient cocaine treatment: preliminary findings.
    Journal of addictive diseases, 1994, Volume: 13, Issue:4

    Topics: Ambulatory Care; Antisocial Personality Disorder; Anxiety Disorders; Carbamazepine; Cocaine; Combine

1994
Antisocial personality disorder as a prognostic factor for pharmacotherapy of cocaine dependence.
    Drug and alcohol dependence, 1994, Volume: 35, Issue:1

    Topics: Adult; Amantadine; Antisocial Personality Disorder; Cocaine; Combined Modality Therapy; Comorbidity;

1994
Desipramine treatment for cocaine dependence. Role of antisocial personality disorder.
    The Journal of nervous and mental disease, 1994, Volume: 182, Issue:3

    Topics: Adult; Antisocial Personality Disorder; Cocaine; Comorbidity; Desipramine; Humans; Male; Methadone;

1994

Other Studies

2 other studies available for desipramine and Antisocial Behavior

ArticleYear
A preliminary study of desipramine in the treatment of cocaine abuse in methadone maintenance patients.
    The Journal of clinical psychiatry, 1987, Volume: 48, Issue:11

    Topics: Adult; Antisocial Personality Disorder; Black or African American; Cocaine; Desipramine; Female; Hum

1987
[Pertofrane in psychopathy].
    Medizinische Monatsschrift, 1966, Volume: 20, Issue:6

    Topics: Adult; Antisocial Personality Disorder; Desipramine; Female; Humans; Male; Psychopharmacology

1966