desipramine has been researched along with Anoxemia in 8 studies
Desipramine: A tricyclic dibenzazepine compound that potentiates neurotransmission. Desipramine selectively blocks reuptake of norepinephrine from the neural synapse, and also appears to impair serotonin transport. This compound also possesses minor anticholinergic activity, through its affinity to muscarinic receptors.
desipramine : A dibenzoazepine consisting of 10,11-dihydro-5H-dibenzo[b,f]azepine substituted on nitrogen with a 3-(methylamino)propyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In the rat vas deferens (preloaded with 3H-noradrenaline, catechol-O-methyl transferase inhibited, calcium-free solution) ouabain, glucose deprivation or the combination of hypoxia plus presence of lactate were found to induce a carrier-mediated (desipramine-sensitive) outward transport of the 3H-amine." | 3.68 | The energy requirements for the basal efflux of 3H-noradrenaline from sympathetically innervated organs. ( Russ, H; Schömig, E; Trendelenburg, U, 1991) |
| "Cardiac ischemia and anoxia induce massive norepinephrine (NE) release, which is mediated by a reverse operation of uptake-1 and can be suppressed by uptake-1 inhibitors." | 1.30 | Protection of neuronal uptake-1 inhibitors in ischemic and anoxic hearts by norepinephrine-dependent and -independent mechanisms. ( Dart, AM; Du, XJ; Esler, MD; Little, PJ; Woodcock, EA, 1998) |
| "Myocardial ischemia was caused by interruption of perfusion flow in rat heart and simulated by anoxic and glucose-free incubation in human and rat atrial tissue." | 1.29 | Two different mechanisms of noradrenaline release during normoxia and simulated ischemia in human cardiac tissue. ( Hagl, S; Kurz, T; Richardt, G; Schömig, A; Seyfarth, M, 1995) |
| "During anoxia, desipramine (0." | 1.29 | Mechanisms of noradrenaline release in the anoxic heart of the rat. ( Dart, AM; Du, XJ, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (12.50) | 18.7374 |
| 1990's | 7 (87.50) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kurz, T | 1 |
| Richardt, G | 1 |
| Hagl, S | 1 |
| Seyfarth, M | 1 |
| Schömig, A | 1 |
| Arregui, A | 1 |
| Hollingsworth, Z | 1 |
| Penney, JB | 1 |
| Young, AB | 1 |
| Du, XJ | 2 |
| Dart, AM | 2 |
| Hatta, E | 1 |
| Yasuda, K | 1 |
| Levi, R | 1 |
| Matsumoto, T | 1 |
| Ebata, J | 1 |
| Tsujioka, K | 1 |
| Ogasawara, Y | 1 |
| Kajiya, F | 1 |
| Woodcock, EA | 1 |
| Little, PJ | 1 |
| Esler, MD | 1 |
| Russ, H | 1 |
| Schömig, E | 1 |
| Trendelenburg, U | 1 |
| Abrahamsen, J | 1 |
| Nedergaard, OA | 1 |
8 other studies available for desipramine and Anoxemia
| Article | Year |
|---|---|
Two different mechanisms of noradrenaline release during normoxia and simulated ischemia in human cardiac tissue.
Topics: Adrenergic Uptake Inhibitors; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Cyanides | 1995 |
Autoradiographic evidence for increased dopamine uptake sites in striatum of hypoxic mice.
Topics: Animals; Autoradiography; Benzamides; Benzazepines; Binding Sites; Corpus Striatum; Desipramine; Dop | 1994 |
Mechanisms of noradrenaline release in the anoxic heart of the rat.
Topics: Animals; Chromatography, High Pressure Liquid; Desipramine; Electric Stimulation; Exocytosis; Gangli | 1993 |
Activation of histamine H3 receptors inhibits carrier-mediated norepinephrine release in a human model of protracted myocardial ischemia.
Topics: Aged; Carrier Proteins; Desipramine; Female; Histamine Release; Humans; Hypoxia; Male; Middle Aged; | 1997 |
Spatial fluctuation of regional myocardial blood flows.
Topics: Animals; Coronary Circulation; Desipramine; Heart Ventricles; Hypoxia; Oxygen; Rabbits; Radiographic | 1997 |
Protection of neuronal uptake-1 inhibitors in ischemic and anoxic hearts by norepinephrine-dependent and -independent mechanisms.
Topics: Adrenergic Uptake Inhibitors; Animals; Cocaine; Desipramine; Dopamine Uptake Inhibitors; Drug Intera | 1998 |
The energy requirements for the basal efflux of 3H-noradrenaline from sympathetically innervated organs.
Topics: Animals; Atrial Function; Biological Transport; Calcium; Catechol O-Methyltransferase Inhibitors; De | 1991 |
Accumulation of 3H-adrenaline by rabbit aorta.
Topics: Animals; Aorta; Catechol O-Methyltransferase Inhibitors; Clonidine; Cocaine; Desipramine; Epinephrin | 1985 |