Page last updated: 2024-10-25

desipramine and Anesthesia

desipramine has been researched along with Anesthesia in 16 studies

Desipramine: A tricyclic dibenzazepine compound that potentiates neurotransmission. Desipramine selectively blocks reuptake of norepinephrine from the neural synapse, and also appears to impair serotonin transport. This compound also possesses minor anticholinergic activity, through its affinity to muscarinic receptors.
desipramine : A dibenzoazepine consisting of 10,11-dihydro-5H-dibenzo[b,f]azepine substituted on nitrogen with a 3-(methylamino)propyl group.

Anesthesia: A state characterized by loss of feeling or sensation. This depression of nerve function is usually the result of pharmacologic action and is induced to allow performance of surgery or other painful procedures.

Research Excerpts

ExcerptRelevanceReference
"The incidence of halothane-epinephrine arrhythmias increases after the short-term administration of imipramine, probably because of enhanced noradrenergic transmission."7.67Halothane-epinephrine arrhythmias and adrenergic responsiveness after chronic imipramine administration in dogs. ( Maze, M; Smith, CM; Spiss, CK, 1984)
"The incidence of halothane-epinephrine arrhythmias increases after the short-term administration of imipramine, probably because of enhanced noradrenergic transmission."3.67Halothane-epinephrine arrhythmias and adrenergic responsiveness after chronic imipramine administration in dogs. ( Maze, M; Smith, CM; Spiss, CK, 1984)
"Treatment with desipramine did not affect the bradycardia evoked by intrahypothalamic injection of phenylephrine (10 micrograms)."1.27Effects of desipramine on cardiovascular responses of rats to stimulation of the baroreceptor reflex and of central adrenoceptors. ( Poole, S; Stephenson, JD, 1985)
" Acute and chronic administration of various antidepressant agents was examined."1.27Chronic and acute administration of typical and atypical antidepressants on activity of brain noradrenaline systems in the rat thiopentone anaesthesia model. ( Angel, A; Mason, ST, 1984)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-199011 (68.75)18.7374
1990's5 (31.25)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mason, ST1
Angel, A1
Spiss, CK1
Smith, CM1
Maze, M1
Majewski, H2
Hedler, L2
Starke, K2
Filippelli, A1
Cuparencu, B1
Falciani, M1
de Novellis, V1
Safta, L1
Arustei, V1
Rossi, F1
Koganei, H1
Takeuchi, A1
Kimura, T1
Satoh, S1
Abrahams, TP1
Varner, KJ1
Ozawa, H1
Chen, CS1
Watanabe, H1
Uematsu, T1
Halbrügge, T1
Friedgen, B1
Thyen, A1
Graefe, KH1
Blaha, CD1
Phillips, AG1
Daugherty, A1
Frayn, KN1
Redfern, WS1
Woodward, B1
Ensinger, H1
Kalén, P1
Kokaia, M1
Lindvall, O1
Björklund, A1
Yamaguchi, N1
Lamontagne, D1
Boudreau, G1
Nadeau, R1
de Champlain, J1
Poole, S1
Stephenson, JD1
Antonaccio, MJ1
Gisler, RH1

Other Studies

16 other studies available for desipramine and Anesthesia

ArticleYear
Chronic and acute administration of typical and atypical antidepressants on activity of brain noradrenaline systems in the rat thiopentone anaesthesia model.
    Psychopharmacology, 1984, Volume: 84, Issue:3

    Topics: Anesthesia; Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Behavior, Animal; Brai

1984
Halothane-epinephrine arrhythmias and adrenergic responsiveness after chronic imipramine administration in dogs.
    Anesthesia and analgesia, 1984, Volume: 63, Issue:9

    Topics: Anesthesia; Animals; Arrhythmias, Cardiac; Desipramine; Dogs; Drug Interactions; Epinephrine; Female

1984
The noradrenaline rate in the anaesthetized rabbit: facilitation by adrenaline.
    Naunyn-Schmiedeberg's archives of pharmacology, 1982, Volume: 321, Issue:1

    Topics: Anesthesia; Animals; Blood Pressure; Catecholamines; Desipramine; Epinephrine; Heart Rate; Kinetics;

1982
Effects of the intracerebroventricular administration of ketamine on centrogenic arrhythmias in anesthetized rats.
    Research communications in chemical pathology and pharmacology, 1994, Volume: 84, Issue:3

    Topics: Anesthesia; Animals; Arrhythmias, Cardiac; Aspartic Acid; Cerebral Ventricles; Desipramine; Electroc

1994
Effects of yohimbine and desipramine on adrenal catecholamine release in response to splanchnic nerve stimulation in anesthetized dogs.
    Biological & pharmaceutical bulletin, 1995, Volume: 18, Issue:9

    Topics: Adrenal Glands; Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Anesthesia; Animals; Cat

1995
Effects of cocaine on adrenal sympathetic nerve discharge in anesthetized rats.
    Physiology & behavior, 1998, Feb-15, Volume: 63, Issue:4

    Topics: Adrenal Glands; Anesthesia; Animals; Blood Pressure; Cocaine; Desipramine; Dose-Response Relationshi

1998
Effect of clonidine on blood pressure, heart rate and body temperature in conscious rats.
    Japanese journal of pharmacology, 1977, Volume: 27, Issue:1

    Topics: Anesthesia; Animals; Atropine; Blood Pressure; Body Temperature; Chlorpromazine; Clonidine; Desipram

1977
The involvement of desipramine-sensitive processes in the extraction of various catecholamines from plasma in the anaesthetized rabbit.
    Journal of neural transmission. Supplementum, 1990, Volume: 32

    Topics: Anesthesia; Animals; Catecholamines; Desipramine; Dopamine; Epinephrine; Female; Isoproterenol; Male

1990
Application of in vivo electrochemistry to the measurement of changes in dopamine release during intracranial self-stimulation.
    Journal of neuroscience methods, 1990, Volume: 34, Issue:1-3

    Topics: Anesthesia; Animals; Brain; Desipramine; Dopamine; Electrochemistry; Male; Neurotransmitter Uptake I

1990
The role of catecholamines in the production of ischaemia-induced ventricular arrhythmias in the rat in vivo and in vitro.
    British journal of pharmacology, 1986, Volume: 87, Issue:1

    Topics: Adrenal Medulla; Adrenalectomy; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthesi

1986
Neuronal and postjunctional components in the blood pressure effects of dopamine and bromocriptine in rabbits.
    The Journal of pharmacology and experimental therapeutics, 1985, Volume: 234, Issue:3

    Topics: Anesthesia; Animals; Benzazepines; Blood Pressure; Bromocriptine; Clonidine; Decerebrate State; Desi

1985
Basic characteristics of noradrenaline release in the hippocampus of intact and 6-hydroxydopamine-lesioned rats as studied by in vivo microdialysis.
    Brain research, 1988, Dec-06, Volume: 474, Issue:2

    Topics: Anesthesia; Animals; Desipramine; Dialysis; Female; Halothane; Hippocampus; Hydroxydopamines; Inject

1988
Effects of yohimbine and desipramine on cardiac noradrenaline release and ventricular arrhythmias during acute coronary artery occlusion and reperfusion in anesthetized dogs.
    Canadian journal of physiology and pharmacology, 1987, Volume: 65, Issue:11

    Topics: Anesthesia; Animals; Arrhythmias, Cardiac; Blood Pressure; Coronary Circulation; Coronary Vessels; D

1987
Effects of desipramine on cardiovascular responses of rats to stimulation of the baroreceptor reflex and of central adrenoceptors.
    Neuropharmacology, 1985, Volume: 24, Issue:9

    Topics: Adenylyl Cyclases; Administration, Oral; Anesthesia; Animals; Blood Pressure; Brain; Desipramine; He

1985
Paradoxical vagal tachycardia in ganglion-blocked anesthetized dogs.
    European journal of pharmacology, 1974, Volume: 28, Issue:1

    Topics: Adrenergic beta-Antagonists; Anesthesia; Animals; Atropine; Blood Pressure; Bretylium Compounds; Chl

1974
Stress and the hormonal regulation of the immune response in mice.
    Psychotherapy and psychosomatics, 1974, Volume: 23, Issue:1-6

    Topics: Acceleration; Adrenal Cortex Hormones; Adrenal Glands; Adrenalectomy; Adrenocorticotropic Hormone; A

1974