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desipramine and Agoraphobia

desipramine has been researched along with Agoraphobia in 11 studies

Desipramine: A tricyclic dibenzazepine compound that potentiates neurotransmission. Desipramine selectively blocks reuptake of norepinephrine from the neural synapse, and also appears to impair serotonin transport. This compound also possesses minor anticholinergic activity, through its affinity to muscarinic receptors.
desipramine : A dibenzoazepine consisting of 10,11-dihydro-5H-dibenzo[b,f]azepine substituted on nitrogen with a 3-(methylamino)propyl group.

Agoraphobia: Obsessive, persistent, intense fear of open places.

Research Excerpts

ExcerptRelevanceReference
"Fourteen patients who met DSM-III criteria for agoraphobia with panic attacks received 200 mg desipramine (DMI) per day for 12 to 16 weeks on an open basis."7.67Desipramine in agoraphobia with panic attacks: an open, fixed-dose study. ( Lydiard, RB, 1987)
" Among the more important recent discoveries are the efficacy of the tricyclic antidepressants for panic disorder and agoraphobia with panic attacks; the use of the monoamine oxidase inhibitors for the above disorders and for atypical depression and hysteroid dysphoria; the use of propranolol for anxiety disorders and for uncontrollable violent outbursts; the antianxiety and antipanic effects of clonidine; and the usefulness of lithium in treating schizophrenia and schizoaffective disorder and for emotionally unstable character disorders."4.76Newer uses for older psychotropic medications. ( Liebowitz, MR, 1982)
"Fourteen patients who met DSM-III criteria for agoraphobia with panic attacks received 200 mg desipramine (DMI) per day for 12 to 16 weeks on an open basis."3.67Desipramine in agoraphobia with panic attacks: an open, fixed-dose study. ( Lydiard, RB, 1987)
"Ten cases are presented--two in detail--in which clonazepam was used successfully in patients with treatment-resistant panic disorder with or without agoraphobia."3.67Successful use of clonazepam in patients with treatment-resistant panic disorder. ( Rosenbaum, JF; Tesar, GE, 1986)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-199010 (90.91)18.7374
1990's1 (9.09)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Liebowitz, MR3
Mavissakalian, M2
Perel, JM1
Michelson, L2
Perel, J1
Fyer, AJ2
Gorman, JM2
Dillon, D2
Appleby, IL1
Levy, G1
Anderson, S1
Levitt, M1
Palij, M1
Davies, SO1
Sheehan, DV1
Kalus, O1
Asnis, GM1
Rubinson, E1
Kahn, R1
Friedman, JM1
Iqbal, N1
Grosz, D1
van Praag, H1
Cahn, W1
Cohen, BS1
Klein, DF1
Lydiard, RB2
Tesar, GE1
Rosenbaum, JF1

Reviews

2 reviews available for desipramine and Agoraphobia

ArticleYear
Newer uses for older psychotropic medications.
    Hospital & community psychiatry, 1982, Volume: 33, Issue:4

    Topics: Adrenergic beta-Antagonists; Agoraphobia; Anxiety Disorders; Bipolar Disorder; Clonidine; Depressive

1982
Current concepts in psychiatry. Panic attacks and phobias.
    The New England journal of medicine, 1982, Jul-15, Volume: 307, Issue:3

    Topics: Adolescent; Adult; Agoraphobia; Antidepressive Agents; Anxiety Disorders; Behavior Therapy; Clinical

1982

Trials

3 trials available for desipramine and Agoraphobia

ArticleYear
The relationship of plasma imipramine and N-desmethylimipramine to improvement in agoraphobia.
    Journal of clinical psychopharmacology, 1984, Volume: 4, Issue:1

    Topics: Adult; Agoraphobia; Desipramine; Female; Humans; Imipramine; Male; Phobic Disorders

1984
Current concepts in psychiatry. Panic attacks and phobias.
    The New England journal of medicine, 1982, Jul-15, Volume: 307, Issue:3

    Topics: Adolescent; Adult; Agoraphobia; Antidepressive Agents; Anxiety Disorders; Behavior Therapy; Clinical

1982
Desipramine treatment in panic disorder.
    Journal of affective disorders, 1991, Volume: 21, Issue:4

    Topics: Adult; Agoraphobia; Anxiety Disorders; Arousal; Desipramine; Female; Humans; Male; Panic; Personalit

1991

Other Studies

7 other studies available for desipramine and Agoraphobia

ArticleYear
The relationship of plasma imipramine and N-desmethylimipramine to improvement in agoraphobia.
    Psychopharmacology bulletin, 1984,Winter, Volume: 20, Issue:1

    Topics: Agoraphobia; Desipramine; Humans; Imipramine; Phobic Disorders

1984
Lactate provocation of panic attacks. I. Clinical and behavioral findings.
    Archives of general psychiatry, 1984, Volume: 41, Issue:8

    Topics: Adult; Agoraphobia; Anxiety Disorders; Clonidine; Desipramine; Fear; Female; Humans; Imipramine; Lac

1984
The course of panic attacks and agoraphobia.
    Archives of general psychiatry, 1988, Volume: 45, Issue:5

    Topics: Agoraphobia; Anxiety; Chronic Disease; Desipramine; Fear; Follow-Up Studies; Humans; Panic; Phobic D

1988
Antipanic drug effects during lactate infusion in lactate-refractory panic patients.
    Psychiatry research, 1987, Volume: 21, Issue:3

    Topics: Adult; Agoraphobia; Alprazolam; Clonidine; Desipramine; Fear; Female; Fluoxetine; Humans; Imipramine

1987
Preliminary results of an open, fixed-dose study of desipramine in panic disorder.
    Psychopharmacology bulletin, 1987, Volume: 23, Issue:1

    Topics: Adult; Aged; Agoraphobia; Desipramine; Fear; Female; Humans; Male; Middle Aged; Panic; Phobic Disord

1987
Desipramine in agoraphobia with panic attacks: an open, fixed-dose study.
    Journal of clinical psychopharmacology, 1987, Volume: 7, Issue:4

    Topics: Adult; Aged; Agoraphobia; Desipramine; Fear; Female; Humans; Male; Middle Aged; Panic; Phobic Disord

1987
Successful use of clonazepam in patients with treatment-resistant panic disorder.
    The Journal of nervous and mental disease, 1986, Volume: 174, Issue:8

    Topics: Adult; Agoraphobia; Alprazolam; Anxiety Disorders; Benzodiazepines; Benzodiazepinones; Clonazepam; D

1986